Cluster Biomedizintechnik Kooperationsmodell und ......MedTech Training Center: part of the...

Vision. Konzept. Realisierung Februar 2015

Cluster Biomedizintechnik

Kooperationsmodell und Forschungstrends

RWTH Aachen Campus Seite 2

Die RWTH Aachen University:

Eine der stärksten MINT-Universitäten Deutschlands

Quellen: RWTH Aachen Dezernat 6.0 Abteilung 6.3 (2014), Rankingreport der RWTH 2014

Studierende nach Wissenschaftsbereichen

7%

57%

23%

Natur-

wissenschaften

Ingenieur-

wissenschaften Medizin

Geistes-,

Gesellschafts-

und Wirtschafts-

wissenschaften

Finanzvolumen 2013: 894 Mio. €

davon Drittmittel: 354 Mio. €

An-Institute: 66 Mio. €

Studierende: >42 Tsd.

Professuren: 512

Institute, davon 260

Großinstitute 22

Fraunhofer 4

Graduiertenprogramme 25

Wirtschaftswoche 2014

2. Platz Maschinenbau

1. Platz Elektrotechnik

2. Platz Wirtschaftsingenieure

1. Platz Naturwissenschaften

2. Platz Informatik

Wettbewerber:

Karlsruhe, Darmstadt, München

DFG-Förderranking

2012 (€ Mio.)

Hochschulrankings Statistik

278 264 251

RWTHAachen

LMUMünchen

FU Berlin

13%


Die Maßnahme: Ein zusammenhängender Campus für

Forschen. Lernen. Entwickeln. Leben.

Campus West

Campus Mitte

Campus Melaten

Existierender Campus Campus-Erweiterung

AC Zentrum

Uniklinik

Das Campus-Projekt sichert das

weitere Wachstum der RWTH

Aachen University

Es folgt dem Leitsatz

„Forschung braucht Fläche“

Ein zusammenhängender

Campus entsteht, der in das

öffentliche Leben integriert ist

Die Fläche wächst um

800.000 m² auf 2,5 km²

Das Investitionsvolumen

beträgt ca. 2 Mrd. €

10.000 Arbeitsplätze werden

direkt und indirekt geschaffen © StädteRegion Aachen/RWTH Aachen Campus GmbH


Der Fokus: Relevante Fragen in 19 Forschungsclustern

Nachhaltige

Entergie

n.n.

Biomedizin-

technik

Logistik

Verfahrens-

technik

Photonik

Produktions-

technik

Molekulare

Technologie

& Katalyse

Kfz-Antriebs-

stränge

Schwerlast-

antriebe

Kunststoff-

technik

Alternative

Kraftstoffe

Faser-

verbundwerk-

stoffe

n.n.

Georessour-

cen/

Advanced

Metals and

Processes

Informations-

&

Kommunika-

tionstechno-

logie

n.n.

Weiße &

Grüne Bio-

technologie

Ultra High

Speed Mobile

Information &

Communi-

cation Geplantes Cluster

Startcluster


Der Anspruch:

Relevante Themen schnell mit visionären Ideen angehen

© Shutterstock


RWTH Aachen Campus:

catalyst for research and trigger for innovation

Research today • Long development times

• Narrow scope for solution

Solution Space

time

Knowing,

who knows

what.

Research yesterday • Long development times

• Narrow scope for solutions

Solution Space

time

Knowing,

where it

is written.

Research tomorrow • Shortened development times

• Ample room for solutions

Solution Space

time

Knowing,

where

knowledge

is created.


“Enrollment of companies“: Cooperation model

to strengthen cooperation between industry and university

Research & Development

Advanced (vocational)

training

Industry

Research questions, resources, qualified staff

Research results,

resources, qualified staff

Development

RWTH

Lecturers, visiting professors, cases, resources

Qualified staff, certificates,

masters, doctorates

Enrollment

As a precondition for the constant and sustainable generation of third-party funds, there need to be

enough space for research and development.

Integrated and systemic research

Integration of competences and

disciplines in line with demand

Attractive range of services on

offer

Stabilize cooperation

Clear assignment of roles and

responsibilities

Access to resources and

technologies

Exploitation of synergistic effects

and economies of scale

RWTH Aachen Campus Symbiosis of science and

industry


RWTH Aachen Campus: Aktuelle Entwicklungen

Cluster

Logistik

eLab – Fertigstellung

Sommer 2015

© LP12

Cluster

Nachhaltige Energie

E.ON Energy

Research Center

Cluster

Photonik

Fertigstellung

Herbst 2015

© KPF

Bilinguale

Kindertagesstätte

Bezug

Dezember 2014

© Campus GmbH

Cluster

Schwerlastantriebe

CWD – Bezug

Frühjahr 2015

© BLB NRW

Cluster

Produktionstechnik

Fertigstellung

Herbst 2016

© Henn

1 2

3

4

5

6

© RWTH Campus/Peter Winandy

Cluster

Biomedizintechnik

CBMS – Baubeginn

Frühjahr 2015

© C&P © RKW

7

1 2 3 4 5 6 7


Cluster Biomedizintechnik: Erweiterung 2015 bis 2017

CBMS

ZBMT

C+P

Helmholtz Institute Biomedical Engineering

NGP2

University Hospital

ZBMT II

Leibniz

Institute Interactive

Materials

MTZ MedTech

Training

Center

© AME/RWTH


ZMBT is a cornerstone of the

Campus activities.

The ZMBT is a joint project of

the City of Aachen, AGIT and

Campus GmbH.

GFA : 4.100 m²

- 25% of the space for newly

founded companies

- 75% of the space for

Campus companies

Tenants: 10 companies with a

total of 120 employees

The Center for Bio-Medical Engineering (ZBMT)

was the first new Campus building to be completed in July 2011

Source: Carpus + Partner AG, Aachen


The first company moved into a second building on Biomedical

Engineering Cluster in 2011

This building for a planning and consultancy company specializing in life sciences is embedded in the

Bio-Medical Engineering Cluster

Headquarters of the firm of

Carpus + Partner AG with

around 200 employees

Specialization in Life

Sciences and High-Tech

Industries

Internationally operative

planning and consultancy

company

Open space office with more

than 3.700 square meters of

gross floor area for around

140 employees




Biohybrid Implants (Cardiovascular and Lung)

Biohybrid Nanocarriers (Tumor Therapy)

System Labs: Prototype Production Lines

Experimental Imaging Facility

Completed by Feb. 2017

Center for Biohybrid Medical Systems - CBMS


System Labs

Center for Biohybrid Medical Systems - CBMS


sketch: rha reicher haase + associierte, Aachen

MedTech Training Center: part of the Biomedical Engineering Cluster

University Hospital

BME Cluster

MedTech

Training Center

Lehrgebäude

2.500 m² (brutto)

Dienstleister

500 m² (brutto)

Fort- und Weiterbildung

500 m² (brutto)

Multifunktionssaal

500 m² (brutto)


Cluster Biomedizintechnik: Forschungsthemen

• Medizinische Bildgebung & Bildgeführte Therapie

• Organunterstützung & Intelligente Implantate

• Biohybride Systeme & Tissue Engineering

• Personal Health Care & Telemonitoring

26.02.2

015

Folie Nr.

16

I3-Assist

Individual, Interactive & Integrated

Cardiopulmonary Assist

• Tailored gas exchanger by

modularity of components

• Adaption to individual disease-

specific course

26.02.20

15

Folie Nr.

17

MiGi

Multifunctional Image

Guided Interventions

MRI-safe guide wire

Marker Technology

Coating Technology

Micro-Pullwinding Technology

MiGi – Multifunctional Image Guided Interventions

0

10

20

30

40

0 10 20 30 40 50

Young's

modulu

s [G

Pa

]

Winding angle [°]

Adaptation of mechanical properties

in continuous process

Optimization

of marker setup

(different marker

materials,

concentrations

and distances)

Coeff

icie

nt of

slid

e f

rictio

n

Cycle no.

Evaluation of optimum

coating process

(pretreatment, friction

coefficient, wear

resistance)

Successful

in-vivo

testing with

real-time MRI

sequence

Soft tip Rigid shaft

Hydrophilic

coating MRI markers

3-layered

body

26.02.20

15

Folie Nr.

19

HyTher

Interventionelle Hybridtherapie

HyTher

Image-guided interventional

hybrid therapy

Planning / Navigation Software, 3D-Visualization

3D Beschleunigungssensor

Auflagefläche



aufgespannte Ebene

w/o breathing detection with breathing detection

Movement / Breathing Compensation

Navigated placement of ballon-mounted stent

into right renal artery

Electromagnetically navigated in-situ fenestration

BioMon - HF

Biomonitoring in heart failure

• Detection of heart insufficiency and

concomittant diseases (hypertension,

atrial fibrillation, sleep apnea)

• Solution: Multisensor approach

Folie Nr. 23

TemRas

Telemedical Rescue Assistance System

26.02.2015

Telemedizinisches Rettungsassistenzsystem

Realisierung einer umfassenden, nahtlosen und situationsgerechten

Versorgungskette kardiovaskulärer Notfälle durch Telemedizin

26.02.2

015

Folie Nr.

25

PATIM

Generation & imaging

of patient customized implants

Tissue Eng Part A 2009, Biomaterials 2010

GoreTex Graft Biohybrid Implant

subtotal stenosis

Ovine Model, Carotid Artery, Explantation after 6 Month

technical:

textile scaffold

biological:

fibrin gel + cells

Biohybrid Vascular Graft - In Vivo Study

Imaging of Patient Customized Biohybrid Implants

Integration of biomarkers

In vivo monitoring of implants

Hemocompatibility

Inflammation

„Fate“ of implanted cells:

Integration

Remodelling

Degradation

PET-MRI


Products & Spin-off Companies

Medos HIA VAD

Medos DeltaStream Impella® Recover® Circulite Synergy

28


Vielen Dank für Ihre Aufmerksamkeit

© rha

Prof. Dr. Thomas Schmitz-Rode

Clusterleiter Biomedizintechnik

Institut für Angewandte Medizintechnik

RWTH Aachen University

Pauwelsstraße 20

52074 Aachen

Tel. 0241 – 80 87111

E-Mail [email protected]

URL www.rwth-campus.com

www.ame-hia.de

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