INSTAND - 00 complete databaseinterlab.lt/image/data/PDF/Instand 2020.pdf · Molecular genetics 01...

2020

Program

of External Quality Assessment Schemes in Medical Laboratories

Version: 01.10.2019

INSTAND Gesellschaft zur Förderungder Qualitätssicherung in medizinischen Laboratorien e. V.

Ubierstr. 2040223 Düsseldorf, Germany

Postfach 25 02 11 40093 Düsseldorf, Germany

T +49 [0] 211 1592 13-0

F +49 [0] 211 1592 13-30 E [email protected] I www.instand-ev.de

Prof. Dr. med. Michael Spannagl President of INSTAND e. V.

Prof. Dr. rer. nat. Ingo Schellenberg Vice President of INSTAND e. V.

Prof. Dr. med. Klaus-Peter Hunfeld Vice President of INSTAND e. V.

PREFACE

INSTAND, the Society for Promoting Quality Assurance in Medical Laboratories, has been conducting EQA testing in the field of hematology since 1968 and in all areas of in vitro diagnostic testing since 1970. Our roughly 30 staff members provide you with more than 370 EQA tests for external quality assurance in laboratory diagnostics, which are in line with the current guidelines of the German Medical Association (Rili-BÄK). We send out around 165,000 samples annually to the approximately 12,500 laboratories participating in our EQA tests.

Please refer to pages 10–16 in our program booklet for the mandatory participation parameters in accordance with the regulations of the German Medical Association (B 1, B 2, B 3 and B 5). They are marked orange in the EQA section. The current guideline of the German Medical Association can be found on the Internet (www.baek.de).

Our online system for EQA tests has proven to be an easy and user-friendly way to place orders and enter values online: https://rv-online.instandev.de/ The widespread acceptance of our online platform means that most of our paper forms will be replaced by online data entry by July 2020.

As an indication of our consistent professional and scientific development, nine more EQA tests will be offered in 2020:

Group 427: Mycobacteria diagnostics 01 – Sensitivity testing of non-tuberculous mycobacteria Group 404: Virus genome detection – Borna disease viruses Group 405: Virus genome detection – Human herpesvirus 6 (HHV-6) Group 406: Virus genome detection – Human herpesvirus 8 (HHV-8) Group 407: Virus genome detection – Parechovirus Group 408: Virus genome detection – Torque teno virus (TTV) Group 415: Virus immunology – Borna disease viruses (AB) Group 433: Virus genome detection – Panel for viral meningitis / encephalitis for multiplex tests

and in cooperation with the Reference Institute for Bioanalytics (RfB): Group 785: Newborn screening.

Please be sure to observe the deadlines for registering and deregistering, otherwise we cannot guarantee that you will be registered for the EQA. If you already have a subscription, you will not receive a registration form. You can also download the form from our website: www.instand-ev.de.

We look forward to continuing our good and pleasant working relationship with you.

3/156

INSTAND – External Quality Assessment Program 2020

4/156

German Society for Extracellular Vesicles

Sektion Immunhämatologie/-genetik

Gemeinsames Jahressymposium

01.

–

03. März 2018

Kap Europa. Messe Frankfurt.

Weitere Informationen und Anmeldeformular ab Herbst 2017 auf www.igld.de

SAVE THE DATE

Common annual symposium

Kap Europa. Trade fair Frankfurt.05. – 07. March 2020

Further information and application form: autumn 2019 on www.igld.de

Save The Date_IGLD_Frankfurt 2019_180727.indd 2 27.07.2018 13:10:57

5/156

Contents

According to the Guidelines of the Federal Medical Association of Germany of Quality Assurance in Medical Laboratories the mandatory analytes of the EQA schemes are color–coded in this brochure.

No. Survey EQAS Expert Page

ListofRili–BÄKparameterssubjecttospecificpartsofB1,B2,B3andB5 10–15

720 Allergy Diagnostic Schellenberg/Zouboulis 16

AutoImmuneDiseases

251–275 AutoimmuneDiseases01–13 Blüthner/Stern/Seelig 16–19

653 BasophilActivationTest Sack/Boldt 19

CellularImmunodeficiencyDiagnostic(Cytometry) Sack/Boldt 20

25–28

21–23Immunogenetics–HLA

Moleculargenetics01

Moleculargenetics02

23,24

28,29

Moleculargenetics03 29–34

Moleculargenetics04 34,35

Lachmann/Zaralioglu

Flörke/KappertFlörke/

KappertChristensen/

KappertMaly/Fried

Kreuzer/Kleinert

Frömmel/Méndez

35

Haematology01–BloodCellCount Dorn–Beineke/Nebe 36

Haematology07–BloodSmearAnalysis Diem/Baurmann 36

Haematology09–BoneMarrowCytology Haferlach/Gassmann 36

Haematology16–FreeHaemoglobin vonAhsen/Klouche 37

Haematology03–BloodCellCount–QBCSystem Dorn–Beineke/Nebe 37

Haematology04–ReticulocyteAnalysis02 Nebe/Gutensohn 37

(Machine–BasedAnalysis)

Haematology06–DifferentialBloodCount Dorn–Beineke/Nebe 37

(Machine–BasedAnalysis)

Haematology14–Immunophenotyping03 Humpe/Gutensohn 38

(T,BandNKcellsincellularproducts)

Haematology05–ReticulocyteAnalysis01 Nebe/Gutensohn 38

(Microscopy)

Haematology10–Immunophenotyping01 Kern/Schabath 38

Haematology11–Stem/ProgenitorCells(CD34) Gutensohn/Humpe 38

Haematology12–Immunophenotyping02 Schabath/Kern 39

Haematology15–Haemoglobinopathies Frömmel/Méndez 39

Haematology13–PNHDiagnostics Höchsmann/Nebe 39

Haemostasis01 Spannagl/Dick 40

Haemostasis02–05,07 Spannagl/Dick 40,41

Haemostasis06–D–Dimer Spannagl/Peetz/Dick 41

Haemostasis10,12–15 Peetz/Spannagl/Dick 41,42

Haemostasis17–Compact Spannagl/Dick 43

Haemostasis20–FunctionalAPCResistance Spannagl/Dick 43

651

Genetics

440–445

730–735

739–749,793,

738,790–792

770–784,786–788

765–769,

794

Haematology

211

212

218

236

209

216

612,912

617

215

213

217

214

210

616,916,917

Haemostasis

221

222–225,227

226

230,280–283

285

288

501–504 Haemostasis21–23,25 Peetz/Spannagl/Dick 43,44

509 Haemostasis31–ROTEMSigma Spannagl/Dick 44

505 Haemostasis32–Edoxaban Peetz/Spannagl/Dick 44

6/156

Contents


286 Haemostasis18–POCT Giebl/Spannagl 45

220,228,287, Haemostasis08,11,19,24,26,27,30 Spannagl/Dick/Kiefel 45–48

289,510,511,514

512–513 Haemostasis28,29– Spannagl/Dick 49

BleedingDisorderCaseStudy+DNAfor512

630 ACE(Angiotensin–Converting–Enzyme) Durner/N.N. 50

ClinicalChemistryandLaboratoryMedicine

750,751 MarkersofEthanolAbuse01+02 Luppa/Schneider 50

710 AminoAcidAnalysis N.N./Schadewaldt 51

118 Ammonia Falck/Nauck 51

322 InfectionSerology–C–ReactiveProtein Hunfeld/N.N. 51

185 BiogenicAmineinPlasma Schneider/Luppa 52

760 MyocardialMarkers Baum/Peetz 52

761 MyocardialMarkersBNP Baum/Peetz 52

141 SerumProteins/Electrophoresis Niederau/Schellenberg 52

700 Ethanol Schellenberg/Falck 53

130 FecalDiagnostics01 Durner/Spannagl 53

131 FecalDiagnostics02 Durner/Spannagl 53

146 Fructosamine Niederau/Kaiser 53

243 Gammopathies Peetz/Niederau 54

111 Glucose–ConventionalAnalysis Niederau/Falck 54

500 UrinaryStoneAnalyses Neubeck/Reuner 54

244 IgGSubclasses Schellenberg/Falck 54

102 CapillaryZoneElectrophoresis Niederau/Schellenberg 55

100 ClinicalChemistry–ConventionalAnalysis Falck/Niederau 55

151 Lipids/Lipoproteins Niederau/N.N. 55

110 NeonatalBilirubin Niederau/Falck 56

181 PhotometerControls Kaiser/Kramer 56

241 Plasmaproteins01 Schellenberg/Falck 56

242 Plasmaproteins02–Cystatin–C Schellenberg/Falck 56

240 Plasmaproteins03–hsCRP Schellenberg/Falck 57

292 TumorMarkers Holdenrieder/Peetz 57

299 TumorMarkers–Calcitonin/Pro–Gastrin–ReleasingPeptide Holdenrieder/Peetz 57

293 TumorMarkers–PSAandTestosterone Holdenrieder/Peetz 57

290 Vitamins01(Serum) Niederau/Schellenberg 58

291 Vitamins02(WholeBlood) Niederau/Schellenberg 58

296 Vitamins03–VitaminC Niederau/Schellenberg 58

187 Vitamins04–MethylmalonicAcid Niederau/Schellenberg 58

245,246 ComplementAnalysis01+02 Prohaszka/Kirschfink 59

247–250 ComplementAnalysis03–06 Prohaszka/Kirschfink 59,60

145 HbA1c Kaiser/Kramer 60

205–208 TraceElements01–04 Kaiser/Kramer 61

TraceElements

304 Hormones–Aldosterone Luppa/Schneider 62

Hormones

301 Hormones–CalciumMetabolism/SpecialThyroid Durner/Luppa 62

297 Hormones–Fertility Maly/Lutz 62

7/156

188 SystematicToxicologicalAnalysis(STA) Hallbach/Schneider 77

193 Antibacterials–Teicoplanin Steimer/Schneider 68

Contents


298 Hormones–AdrenalGland/Pituitary Luppa/Schneider 62

300 Hormones–Pancreas/GastrointestinalTract Durner/Luppa 63

294 Hormones–ThyroidHormones Durner/Luppa 63

295 Hormones–ThyroidGlandAntibodies Durner/Luppa 63

302 Hormones–SteroidHomones,ThyroidGland Luppa/Schneider 63

309 Hormones–Virilization Maly/Lutz 64

305 Hormones–Gravidity–1stTrimesterScreening Maly/Lutz 64

306 Hormones–Gravidity–2ndTrimesterScreening Maly/Lutz 64

626 HematopoeticGrowthFactors Wenzel/Geisen 64

625 PreeclampsiaMarker Luppa/Schneider 65

460,462–464 CerebrospinalFluidAnalysis01–04 Uhr/Zimmermann/Reiber 66,67

CSF

465 CerebrospinalFluidAnalysis05–Neuroborreliosis Zimmermann/Uhr 67

466 CerebrospinalFluidAnalysis06–DementiaMarkers Uhr/Zerr/Reiber 67

194 ParacetamolandNSAIDs Steimer/Schneider 68

TDM/DrugsofAbuseTesting

190 Antiarrhytmics–Amiodaron Steimer/Schneider 68

870 RespiratoryStimulants–Caffeine Steimer/Schneider 68

890 Antibacterials02 Schneider/Steimer 69

191,192,871,872 Anticonvulsants01–04 Steimer/Schneider 69,70

198 Antifungals/Chloramphenicol Steimer/Schneider 70

602 Antifungals/Immunosuppressants vonAhsen/Kaiser 70

200,873–875 AntipsychoticDrugs01–04 Steimer/Schneider 70,71

876–878 Benzodiazepines01–03 Steimer/Schneider 72

601 Immunosuppressants vonAhsen/Kaiser 72

195 TDM01 Steimer/Schneider/Kaiser 73

197 TDM02 Steimer/Schneider/Kaiser 73

860–863 PsychotherapeuticDrugs01–04 Haen/Ridders 73,74

879 Psychostimulants–ADHS–Treatment Steimer/Schneider 74

202 Tri–/TetracyclicAntidepressants03– Steimer/Schneider 74

QuantitativeinSerum

199 TricyclicAntidepressants01–QuantitativeinSerum Steimer/Schneider 75

201 TricyclicAntidepressants02–QuantitativeinSerum Steimer/Schneider 75

203 TricyclicAntidepressants04–QualitativeinSerum Steimer/Schneider 75

204 TricyclicAntidepressants05–QualitativeinUrine Steimer/Schneider 75

850 Antivirals Schneider/Steimer 71

174,176,177 DrugsofAbuseinHumanUrine01–03 Steimer/Niederau 76

(Qualitative+Quantitative)

785 NewbornScreening Hallbach/Spannagl 77

InCooperation

8/156

Contents


171 UrineChemistry01(Qualitative) Fried/Niederau 80

UrineAnalysis

173 UrineChemistry02(Quantitative) Fried/Falck 80

175 UrineChemistry03(BiogeneAmines) Schneider/Lutz 80

178 UrineChemistry04(Porphyrins) Kaiser/Kramer 81

179 UrineChemistry05(Hormones) Kaiser/Kramer 81

172 UrineChemistry06(SedimentPictures) Fried/Niederau 81

530–547 Bacterial Genome Detection Reischl/Ehrenschwender/ 82–86

Microbiology

Fingerle / Anders / Maaß /

Baier / Frangoulidis / Grass /

vonButtlar/Scholz/Dumke

580 BacterialGenomeDetection– Gessner/Reischl 86

MolecularGeneticAnalysisoftheHumanMicrobiome

560 FungalGenomeDetection–Pneumocystisjirovecii Reischl/Reiter–Owona 86

412 Bacteriology–5Samples Schlüter/Ziesing 87

411 Bacteriology–3Samples Schlüter/Ziesing 87

413 Bacteriology – Gram Stain Schlüter/Ziesing 88

310–321,324, InfectionSerology Hunfeld/N.N. 88–92

325,331,332,334

323 InfectionSerology–RheumatoidFactor Hunfeld/N.N. 91

650 InterferonGammaReleaseAssay(IGRA) Sack/Boldt 93

490 Mycology01(Mucorales,Yeasts,Coelomycetes, Haase/Geißdörfer/Schoerner 93

Hyphomycetes,Basidiomycetes)

491 Mycology02(Dermatophytes,Yeasts,MouldFungus) Gräser/Nenoff/Haase 93

480 Mycoserology01–Candida(Antigen+Antibodies) Weig/Bader 94

481 Mycoserology02–Cryptococcusneoformans/ Rickerts/Wilmes 94

CryptococcusgattiiAntigen

492 GenomeDetectionofDermatophytes Gräser/Nenoff 94

456 ParasiteMicroscopy(Blood) Tannich/Loderstädt/ 94

Hörauf/Reiter–Owona

451 ParasiteMicroscopy(Stool) Tannich/Loderstädt 95

452,454,455 ParasiteSerology Hörauf/Reiter–Owona 95

457 DetectionofToxoplasmaDNA(PCR) Hörauf/Reiter–Owona 96

421–426 Mycobacteriology01–06 Hillemann/Andres 96,97

427 Mycobacteriadiagnostics01–DrugSusceptibility Hillemann/Andres 97

Testingofnontuberculousmycobacteria

161 Blood Gas Analysis Luppa/Schneider 78

POCT

162 BloodGasAnalysis–Haemoglobin Dorn–Beineke/Nebe 78

163 BloodGasAnalysis–OPTISystems Luppa/Schneider 78

800 DryChemistry01–POCT:Glucose Petersmann/Nauck 79

810 DryChemistry02–POCT:AbaxisPiccoloSystem Falck/Nauck 79

120 DryChemistry03–POCT:ReflotronSystems Falck/Nauck 79

9/156

399

349,383,384,397, VirusGenomeDetection–ResistanceDetermination Zeichhardt/Kammel 104,107,109,111

368,378,379,382 VirusGenomeDetection–TrainingProgram Zeichhardt/Kammel 104,107,108,110

359,370 VirusDetection(Genome/Antigen) Zeichhardt/Kammel 114,117

Contents


VirusDiagnostics

InformationonVirusDiagnostics 101

340,360–367,369, VirusGenomeDetection Zeichhardt/Kammel 102–119

371–377,380,381,

385–396,400,401,

335–339,341–348, VirusImmunology Zeichhardt/Kammel 122–129

350–358,402,415

430–433 VirusGenomeDetectionforMultiplexTests Zeichhardt/Kammel 120,121

403–408

AddressesoftheEQASchemeExpertsandAssistants 133–145

Index 146–151

Incooperationwith/Imprint 152

ContentsbyGroupno. 153

INSTANDe.V.Calendar2020

When participating in INSTAND EQA schemes our “General Terms and Conditions for Participation in INSTAND External Quality Assessment Schemes” apply exclusively. These are available at www.instand-ev.de/gtc and will be sent to the participant upon request.

231,232 Immunohaematology01+02 Wagner/Geisen 98

TransfusionMedicine

237,238 Immunohaematology05+07(Machine–BasedAnalysis) Wagner/Geisen 98,99

235 Immunohaematology06–MolecularDiagnostic Bein/Flegel/Sachs 99

233 Immunohaematology03–PlateletImmunology Kiefel/Bux/Kroll 99

234 Immunohaematology04–GranulocyteImmunology Bux/Kiefel/Kroll 100

10/156

List of Rili-BÄK parameters subject to specific parts of B 1, B 2, B 3 and B 5

According to the Guidelines of the Federal Medical Association of Germany of Quality Assurance in Medical Laboratories (only for German participants) the mandatory analytes of the EQA schemes are color-coded in this brochure.

Activated partial thromboplastin time (aPTT) QuarterAlanine aminotransferase (ALT or GPT) EC 2.6.1.2 QuarterAlbumin QuarterAlkaline phosphatase (AP) EC 3.1.3.1 QuarterAlpha fetoprotein (AFP) QuarterAspartarte aminotransferase (AST or GOT) EC 2.6.1.1 QuarterBilirubin (total) QuarterCA 15-3 QuarterCalcium (total) QuarterCalcium (ionised) QuarterCarbamazepine QuarterCarcino embryonic antigen (CEA) QuarterChloride QuarterCholesterol (total) QuarterCortisol QuarterCreatine kinase (CK) EC 2.7.3.2 QuarterC-reactive protein (CRP) QuarterDigitoxin QuarterErythrocytes QuarterEstradiol, 17-beta QuarterEthanol clinical toxicology QuarterFerritin QuarterFSH QuarterGamma glutamyl transferase (?-GT) EC 2.3.2.2 QuarterGlucose QuarterHaematocrit QuarterHaemoglobin QuarterHaemoglobin A 1c (HbA1c) QuarterUric acid QuarterUrea QuarterHuman chorionic gonadotropin (hCG) QuarterImmunoglobulin IgA QuarterImmunoglobulin IgG QuarterImmunoglobulin IgM Quarter

QuarterQuarterQuarterQuarterQuarterQuarterQuarterQuarterQuarterQuarterQuarterQuarterQuarterQuarterQuarter

PotassiumCreatinineLactateLactate dehydrogenase (LDH) EC 1.1.1.27LeucocytesLithiumMagnesiumSodiumpCO2PhenobarbitalPhenytoinpO2ProgesteroneProstate-speci ic antigen (PSA)Protein (total)

221, 285, 286100, 120, 810100, 141, 810100, 120, 810

292, 306100, 120, 810

100, 110, 120, 810292

100, 810161, 163

195292

100, 161, 163, 810100, 120, 151, 810

302100, 120, 810241, 322, 810

197211, 612

302700241297

100, 120, 810100, 111, 120, 161, 800, 810

209, 211, 612162, 163, 209, 211, 612

145100, 120, 810

100, 120, 161, 163, 810 292, 306100, 241100, 241100, 241

100, 120, 161, 163, 810 100, 120, 161, 810100, 161, 163, 810

100, 810209, 211, 612100, 161, 195100, 161, 810

100, 161, 163, 810161, 163

195195

100, 810302

292, 293100, 141, 810

>>

Analytes in Plasma / Serum / Whole blood Frequency Group no.B 1a

11/156


Thyroxine, free (fT4) Quarter 294, 302Transferrin Quarter 100, 241Triglycerides Quarter 100, 120, 151, 810Triiodothyronine, free (fT3) Quarter 294, 302Troponin I Quarter 760Valproic acid Quarter 195Vancomycin Quarter 197

>>Testosterone Quarter 293, 302Theophylline Quarter 195Thromboplastin time (Quick) Quarter 221, 285, 286Thrombocytes Quarter 209, 211, 612Thyrotropic hormone (TSH) Quarter 294, 302

Analytes in Plasma / Serum / Whole blood Frequency Group no.B 1a

Albumin Quarter 173Calcium Quarter 173Glucose Quarter 173Uric acid Quarter 173Urea Quarter 173Potassium Quarter 173Creatinine Quarter 173Sodium Quarter 173Protein (total) Quarter 173

Analytes in Urine Frequency Group no.B 1b

Albumin Quarter 460Glucose Quarter 464Immunoglobulin IgA Quarter 460Immunoglobulin IgG Quarter 460Immunoglobulin IgM Quarter 460Lactate Quarter 464Protein (total) Quarter 460

Analytes in Cerebrospinali Fluid

Frequency Group no.B 1c

17-Hydroxyprogesterone Quarter 785IRT Quarter 785PAP Quarter 785TSH Quarter 785

Analytes in dry blood Frequency Group no.B 1d

AB0 characteristics Quarter 231, 232, 237, 238Borrelia burgdorferi, antibodies against (in serum) Half-year 332Borrelia burgdorferi, antibodies against (in CSF) Half-year 465Candida albicans, antibodies against Half-year 480Cannabinoids Quarter 177CD4-T cells Half-year 213CD8-T cells Half-year 213Chromatographic analysis with identification Half-year 188

of the active substance (STA)>>

Qualitative laboratory testing Frequency Group no.B 2

12/156


>>Cocaine and metabolites Quarter 174Differential, blood smear Quarter 212Direct Coombs test Quarter 231, 232, 237, 238dsDNA, autoantibodies against Half-year 251Echinococcus, antibodies against Calendar year 455Entamoeba histolytica, antibodies against Calendar year 455Erythrocyte antigens, antibodies against (Coombs test) Quarter 231, 232, 237, 238Glutaminase, antibodies against Half-year 271HBc antigen, antibodies against Half-year 344HBe antigen, antibodies against Half-year 345HBs antigen, antibodies against Half-year 344Hepatitis-A virus, antibodies against Half-year 343Hepatitis-C virus, antibodies against Half-year 346HIV, antibodies against Half-year 335IgE antibodies, allergen-specific single allergen test; Half-year 720 method-specific control on a rotational basis with 6 chief allergens from the following groups: a) seasonal inhaled allergen, b) year-round inhaled allergen, c) food allergen, d) insect poison allergenImmunoglobulin, oligoclonal (oligoclonal bands) Half-year 462Nuclei (ANA) autoantibodies against Half-year 251

Half-year 357Methadone and metabolites Quarter 176

Half-year 356Opiates Quarter 174Plasmodium, antibodies against Calendar year 454Rhesus type Quarter 231, 232, 237, 238Rheumatoid factor (RF) Quarter 273, 323Rubella virus, antibodies against Half-year 341Schistosoma, antibodies against Calendar year 454Streptococci desoxyribonuclease, antibodies against Half-year 321Streptolysin O, antibodies against Half-year 321Toxoplasmosis gondii, antibodies Half-year 452Treponema pallidum, antibodies against Half-year 311Tricyclic antidepressants Quarter 203, 204Urine sediment Calendar year 172

Half-year 353Cytoplasmatic components of neutrophil granulocytes Half-year 257 (cANCA/pANCA), autoantibodies against

Qualitative laboratory testing Frequency Group no.B 2

13/156


Bacteria

Gram stain Half-year 413Cultivation, identification and sensitivity testing of bacteria Half-year 411, 412Cultivation, identification and sensitivity testing of Half-year 411, 412

fast-growing bacteria and detection of accompanying bacterial flora of the urogenital systemBordetella pertussis, genome detection Half-year 532Borrelia burgdorferi sensu lato, genome detection Half-year 535Chlamydia pneumoniae, genome detection Half-year 540Chlamydia trachomatis, antigen detection Half-year 313, 316Chlamydia trachomatis, genome detection Half-year 530, 531Clostiridium difficile (Toxin Gene), genome detection Half-year 545EHEC/STEC (Shiga toxin), genome detection Half-year 534Helicobacter pylori, genome detection Half-year 533Legionella pneumophila, genome detection Half-year 536Listeria monocytogenes, genome detection Half-year 538Methicillin resistance Staphylococcus aureus (MRSA), Half-year 539

genome detectionMycoplasma pneumoniae, genome detection Half-year 541Neisseria gonorrhoeae, genome detection Half-year 530Salmonella enterica, genome detection Half-year 537Coxiella burnetii, genome detection Half-year 542Francisella tularensis, genome detection Half-year 543

Mycobacteria

Microscopic detection of mycobacteria Half-year 421Cultivation of mycobacteria Half-year 422Differentiation of tuberculosis bacteria Half-year 422Sensitivity test of tuberculosis bacteria Half-year 425, 426Identification of mycobacteria Half-year 423Tuberculosis bacteria, genome detection Half-year 424

Parasites

ParasitesParasites in the blood, microscopic detection Half-year 456Parasites in the stool, microscopic detection Half-year 451Toxoplasma gondii, genome detection Half-year 457

Yeasts

Cultivation and identification of yeasts and hyphomycetes Half-year 490Identification of dermatophytes, yeasts and moulds Half-year 491 (pathogens of dermatomycoses and mucosal yeast infections)Candida, antigen detection Half-year 480Cryptococcus neoformans, antigen detection Half-year 481

>>

Group no.Direct detection and characterisation of infectious agents

Frequency B 3

14/156


Viruses

Adeno viruses, genome detection Half-year 371Cytomegalovirus, genome detection Half-year 365Enteroviruses, genome detection Half-year 372Epstein Barr virus, genome detection Half-year 376Hepatitis A virus, genome detection Half-year 377Hepatitis B virus, genome detection Half-year 361Hepatitis B virus, HBs antigen detection Half-year 344Hepatitis B virus, HBe antigen detection Half-year 345Hepatitis C virus, genome detection Half-year 362Hepatitis C virus genotyping, genome detection Half-year 375Hepatitis C virus, HCV antigen detection Half-year 346Hepatitis E Virus, genome detection Half-year 380Herpes simplex virus type 1/type 2, genome detection Half-year 363HIV 1 (RNA), genome detection Half-year 360HIV 1, p24 antigen detection Half-year 337Human papilloma viruses, genome detection Half-year 373Influenza-A- and -B viruses, genome detection Half-year 370Influenza-A- and -B viruses, antigen detection Half-year 370Measles Virus, genome detection Half-year 386Mumps Virus, genome detection Half-year 387Norovirus, genome detection Half-year 381Parvovirus B19, genome detection Half-year 367Respiratory syncytial virus, genome detection Half-year 359Respiratory syncytial virus, antigen detection Half-year 359Rubella Virus, genome detection Half-year 389Varicella zoster virus, genome detection Half-year 366West Nile Virus, genome detection Half-year 391

>>

Group no.Direct detection and characterisation of infectious agents

Frequency B 3

15/156


Analysis Gene, Gene, Frequency Group no.

Trivial Name HGNC-Name

Alpha1-Antitrypsin AAT, PI1 SERPINA1 Half-year 743Apolipoprotein B 100 APOB APOB Half-year 771Apolipoprotein E APOE APOE Half-year 734, 744Cytochrome p450 2C9 (CYP2C9) CYP2C9 CYP2C9 Half-year 775Cytochrome p450 2C19 (CYP2C19) CYP2C19 CYP2C19 Half-year 777Cytochrome p450 2D6 (CYP2D6) CYP2D6 CYP2D6 Half-year 777Factor V (Leiden) FV Leiden F5 Half-year 730, 740Hereditary haemochromatosis HLA-H HFE Half-year 733, 741HLA-B27 HLA-B HLA-B Half-year 440Lactase-phlorizin-hydrolase LPH LCT Half-year 770Methylenetetrahydrofolate reductase MTHFR MTHFR Half-year 732, 747Plasminogen activator inhibitor I PAI1 SERPINE1 Half-year 735, 748Prothrombin FII F2 Half-year 731, 746Thiopurine S methyltransferase TPMT TPMT Half-year 775Uridyl glucuronyl transferase-1A UGT1 UGT1A1 Half-year 742Vitamin K epoxide reductase VKORC1 VKORC-1 Half-year 775Cystic fibrosis, mucoviscidosis CFTR CFTR Calendar year 778Familial breast/ovarian cancer (BRCA) BRCA1, BRCA2 BRCA1, BRCA2 Calendar year 77921-Hydroxylase deficiency P450-C21 CYP21A2 Calendar year 773

(congenital adrenal hyperplasia)Duchenne and Becker muscular dystrophy Dystrophin DMD Calendar year 780Fragile X syndrome FRAXA FMR1 Calendar year 781Severe hearing impairment Connexin 26 GJB2 Calendar year 782Hereditary nonpolyposis colorectal cancer HNPCC MSH2, MLH1 Calendar year 783Huntington’s disease Huntingtin HTT Calendar year 784Prader-Willi and Angelman syndrome Chr. 15q11-q13 ANCR Calendar year 786Spinal muscle atrophy SMA SMN1 Calendar year 787Wilson’s disease ATPase ATP7B Calendar year 745Y chromosome, microdeletions Azoospermia factor AZF Calendar year 788

Molecular genetic testingB 5

Autoimmune Diseases16/156

AUTO IMMUNE DISEASES

1 set of samples: 5 x lyophilised samples of 1.0 or 0.5 ml serum

participation according to Rili-BÄK: half-yearly

4 samples for determination of inhaled allergens, food allergens and insect poison allergens 1 sample for determination of total IgE

EQA results can only be submitted online!

Deadline for registration Shipment Deadline for receipt of data

Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

07.02.20 06.05.20 20.05.20

July (4)

03.04.20 01.07.20 15.07.20

Oct. (6)

10.07.20 07.10.20 21.10.20

. 720 Allergy Diagnostic Schellenberg / Zouboulis

2 samples of 0.3 ml, serum


Antibodies against cell nuclei (antinuclear antibodies)

ANA anti – DFS70/LEDGF anti – ds-DNA


Mar. (2)

10.01.20 04.03.20 18.03.20

Sep. (5)

26.06.20 26.08.20 09.09.20

. 251 Autoimmune Diseases 01 – Connective Tissue Diseases (ANA) Blüthner / Seelig


anti – Actin anti – H+/K+-ATPase anti – Microsomes (LKM 1) anti – Mitochondria anti – Parietal Cells anti – Smooth Muscle


Mar. (2)

10.01.20 04.03.20 18.03.20

Sep. (5)

26.06.20 26.08.20 09.09.20

. 253 Autoimmune Diseases 02 – Hepatic Syndromes Blüthner / Seelig

Autoimmune Diseases 17/156


Antibodies against ENA

anti – Jo 1 (Histidyl-tRNA-Synthetase) anti – PM / Scl anti – SSA / Ro anti – SSA / Ro (52kD – Proteins) anti – SSA / Ro (60kD – Proteins) anti – SSB / La anti – Sm anti – Sm (D) anti – Topoisomerase-1 (Scl 70) anti – U1 -snRNP (Anti – U1 -70K)


Sep. (5)

26.06.20 26.08.20 09.09.20

. 255 Autoimmune Diseases 03 – Connective Tissue Diseases (ENA) Blüthner / Seelig



Antibodies against neutrophilic granulocytes (ANCA)

anti – MPO anti – PR3 anti – glomerular basement membrane (GBM) c-ANCA p-ANCA


Mar. (2)

10.01.20 04.03.20 18.03.20

Sep. (5)

26.06.20 26.08.20 09.09.20

. 257 Autoimmune Diseases 04 – Vasculitis/Glomerulopathies Blüthner / Seelig


anti-BPAg-1 anti-BPAg-2 anti-Desmoglein-1 anti-Desmoglein-3 anti-Desmoplakin anti-Desmosomes anti-Hemidesmosomes


Mar. (2)

10.01.20 04.03.20 18.03.20

. 259 Autoimmune Diseases 05 – Autoimmune Dermatitis Blüthner / Seelig


anti – Glutamic Acid Decarboxylase (GAD) anti – Islet Cells (ICA) anti – Insulin (IAA) anti – Tyrosine Phosphatase (IA2) anti – Zinc Transporter 8 (ZnT8A)


Sep. (5)

26.06.20 26.08.20 09.09.20

. 261 Autoimmune Diseases 06 – Diabetes mellitus Blüthner / Seelig



anti – Adrenal Cortex anti – P450 C17 -Hydroxylase anti – P450 C21 -Hydroxylase anti – P450 ssc -Hydroxylase


Sep. (5)

26.06.20 26.08.20 09.09.20

. 263 Autoimmune Diseases 07 – Autoimmune Endocrinopathies Blüthner / Seelig


anti – Amphiphysin 1 anti – Glia Cell Nuclear Antibody (AGNA) anti – HuD anti – Neuronal Nuclei anti – Purkinje Cells anti – Ri / Nova 1 anti – SOX1 anti – Ta (Ma 2) anti – Yo (CDR62)


Mar. (2)

10.01.20 04.03.20 18.03.20

. 265 Autoimmune Diseases 08 – Paraneoplastic Neuropathies Blüthner / Seelig


anti – Asialoganglioside (AGA1) anti – Disialoganglioside (GD1a) anti – Disialoganglioside (GD1b) anti – Monosialoganglioside (GM1) anti – Monosialoganglioside (GM2) anti – Monosialoganglioside (GM3) anti – Myelin-associated Glycoprotein (MAG) anti – Quadrosialoganglioside (GQ1b) anti – Trisialoganglioside (GT1b)


Mar. (2)

10.01.20 04.03.20 18.03.20

. 267 Autoimmune Diseases 09 – Peripheral Neuropathies Blüthner / Seelig


anti – Acetylcholin Receptors anti – Musclespecific Receptor Tyrosinkinase (MuSK) anti – Skeletal Muscle anti – Titin


Mar. (2)

10.01.20 04.03.20 18.03.20

. 269 Autoimmune Diseases 10 – Myasthenia gravis Blüthner / Seelig

Autoimmune Diseases 19/156



anti – Endomysium IgA anti – Gliadin IgA anti – Gliadin IgG anti – Transglutaminase IgA anti – deamidated Gliadin IgA anti – deamidated Gliadin IgG


Mar. (2)

10.01.20 04.03.20 18.03.20

Sep. (5)

26.06.20 26.08.20 09.09.20

. 271 Autoimmune Diseases 11 – Gluten-Sensitive Enteropathies Blüthner / Stern / Seelig


participation according to Rili-BÄK: quarterly

Rheumatoid Factor anti – CCP (cyclic citrulline peptide) anti – MCV (mutated citrullinated Vimentin)

Additional terms see EQA No. 323!


Mar. (2)

10.01.20 04.03.20 18.03.20

Sep. (5)

26.06.20 26.08.20 09.09.20

. 273 Autoimmune Diseases 12 – Rheumatoid Arthritis Blüthner / Seelig


anti – Cardiolipin (IgG) anti – Cardiolipin (IgM) anti – ß2-Glycoprotein (IgG) anti – ß2-Glycoprotein (IgM)


Sep. (5)

26.06.20 26.08.20 09.09.20

. 275 Autoimmune Diseases 13 – Antiphospholipid Syndrome Blüthner / Seelig

2 samples of 2.6 ml EDTA whole blood, not stabilized, overnight shippingadditional sample not available

Basophil activation by allergens

No shipping outside Germany possible!



May (3)

20.03.20 18.05.20 26.05.20

Oct. (6)

28.08.20 21.10.20 28.10.20

. 653 Basophil Activation Test Sack / Boldt


EDTA whole blood, not stabilized, overnight shippingadditional sample not available

T, NK and B cell subpopulations including naive, memory, effector, activated, TH1/2 and Treg




May (3)

20.03.20 18.05.20 26.05.20

Oct. (6)

28.08.20 21.10.20 28.10.20

. 651 Cellular Immunodeficiency Diagnostic (Cytometry) Sack / Boldt

Genetics 21/156

GENETICS

5 blood samplesadditional sample not available


Determination of HLA-B27 by molecular and/or serological means


Feb. (1)

08.11.19 20.01.20 12.02.20

Apr. (3)

31.01.20 30.03.20 22.04.20

Aug. (4)

22.05.20 20.07.20 12.08.20

Nov. (6)

04.09.20 02.11.20 25.11.20

. 440 Immunogenetics 01 – HLA-B27 Determination Lachmann / Zaralioglu


Serological typing of HLA class I (HLA A, B) (441-1) and/or HLA class II (HLA-DR, DQ) (441-2); optional determination of HLA-C (441-1)


Feb. (1)

08.11.19 20.01.20 12.02.20

Apr. (3)

31.01.20 30.03.20 22.04.20

Aug. (4)

22.05.20 20.07.20 12.08.20

Nov. (6)

04.09.20 02.11.20 25.11.20

. 441 Immunogenetics 02 – Serology HLA Typing Class I and II Lachmann / Zaralioglu

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

5.6

Genetics22/156


DNA typing of HLA class II: generic HLA-DRB1 (optional -DRB3,4,5) typing (442-1), generic HLA-DQB1 typing (442-2), high-resolution HLA-DRB1 typing (442-3), high-resolution HLA-DQB1 typing (442-4), Rheumatoid-shared epitopes of HLA-DRB1 (442-5), generic to high resolution HLA-DQA1 typing (442-6), generic to high resolution HLA-DPA1 and -DPB1 (442-7)


Feb. (1)

08.11.19 20.01.20 12.02.20

Apr. (3)

31.01.20 30.03.20 22.04.20

Aug. (4)

22.05.20 20.07.20 12.08.20

Nov. (6)

04.09.20 02.11.20 25.11.20

. 442 Immunogenetics 03 – DNA-Based Typing of HLA Class II Lachmann / Zaralioglu

5 samples (buffy coat)additional sample not available

DNA typing of HLA class I: generic HLA-A typing (444-1), generic HLA-B typing (444-2), generic HLA-C typing (444-3), high resolution HLA-A typing (444-4), high resolution HLA-B typing (444-5), high resolution HLA-C typing (444-6), determination of HLA-B*57:01 (444-7)


Feb. (1)

08.11.19 20.01.20 12.02.20

Apr. (3)

31.01.20 30.03.20 22.04.20

Aug. (4)

22.05.20 20.07.20 12.08.20

Nov. (6)

04.09.20 02.11.20 25.11.20

. 444 Immunogenetics 05 – DNA-Based HLA Typing Class I Lachmann / Zaralioglu

5 serum samples

Maximum order: 2 sets of samplesHLA antibody determination: HLA antibody screening by complement-dependent cytotoxicity test (CDC) (445-1) and/or with solid phase immunoassays (445-2), antibody specification by CDC (445-3) and/or antibody specification by solid phase immunoassays (ELISA, Luminex) (445-4), education scheme on HLA antibody detection/specification (445-5)


Feb. (1)

08.11.19 20.01.20 26.02.20

Aug. (4)

22.05.20 20.07.20 26.08.20

. 445 Immunogenetics 06 – HLA Antibody Screening and Specification Lachmann / Zaralioglu

Genetics 23/156

1 serum set (20 Sera) / yearadditional sample not available

HLA crossmatching (lymphocytotoxic crossmatching)

Group 443: only in block with No. 441 August. Registration deadline: 08.11.2019 and shipment of serum samples on 20.01.2020. The HLA crossmatching should be done with the shipping of the group 441 August.


Aug. (4)

08.11.19 20.01.20 26.08.20

. 443 Immunogenetics 04 – HLA Crossmatching Lachmann / Zaralioglu

2 samples of 0.5 ml human blood additional sample not available


Apo E (genotypes 2, 3, 4)


Apr. (2)

17.01.20 18.03.20 15.04.20

Oct. (5)

17.07.20 23.09.20 21.10.20

. 734 Apolipoprotein E (E2, E3, E4) Flörke / Kappert

Molecular genetics 01

2 samples of 0.5 ml human bloodadditional sample not available


Factor V-Leiden


Apr. (2)

17.01.20 18.03.20 15.04.20

Oct. (5)

17.07.20 23.09.20 21.10.20

. 730 Factor V-Leiden-Mutation Flörke / Kappert

Genetics24/156



HFE: C 282 Y HFE: H 63 D HFE: S 65 C


Apr. (2)

17.01.20 18.03.20 15.04.20

Oct. (5)

17.07.20 23.09.20 21.10.20

. 733 HFE H63D, C282Y (optional: S65C) Flörke / Kappert



MTHFR (A 1298 C) MTHFR (C 677 T)


Apr. (2)

17.01.20 18.03.20 15.04.20

Oct. (5)

17.07.20 23.09.20 21.10.20

. 732 MTHFR C677T (optional: A1298C) Flörke / Kappert



Plasminogenactivator-Inhibitor (PAI-1): 4G, 5G


Apr. (2)

17.01.20 18.03.20 15.04.20

Oct. (5)

17.07.20 23.09.20 21.10.20

. 735 PAI-1 (4G/5G) Flörke / Kappert



Prothrombin G20210A


Apr. (2)

17.01.20 18.03.20 15.04.20

Oct. (5)

17.07.20 23.09.20 21.10.20

. 731 Prothrombin G20210A Flörke / Kappert

Genetics 25/156

3 samples, DNA (in 20 µl water) isolated from human leukocytesadditional sample not available


Coagulation:

Factor V-Leiden


Feb. (1)

08.11.19 15.01.20 14.02.20

June (3)

06.03.20 06.05.20 05.06.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 740 Set 01-A – Factor V-Leiden-Mutation Flörke / Kappert



Coagulation:

HPA: 1a, 1b


Feb. (1)

08.11.19 15.01.20 14.02.20

June (3)

06.03.20 06.05.20 05.06.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 749 Set 01-B – Fibrinogen Receptor HPA 1a/1b Flörke / Kappert


Coagulation:

Collagen receptor GP Ia/IIa (C 807 T)


Feb. (1)

08.11.19 15.01.20 14.02.20

June (3)

06.03.20 06.05.20 05.06.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 739 Set 01-C – Collagen Receptor C807T Flörke / Kappert

Genetics26/156



Coagulation:

MTHFR (A 1298 C) MTHFR (C 677 T)


Feb. (1)

08.11.19 15.01.20 14.02.20

June (3)

06.03.20 06.05.20 05.06.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 747 Set 01-D – MTHFR C677T (optional A1298C) Flörke / Kappert



Coagulation:

Plasminogenactivator-Inhibitor (PAI-1): 4G, 5G


Feb. (1)

08.11.19 15.01.20 14.02.20

June (3)

06.03.20 06.05.20 05.06.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 748 Set 01-E – PAI-1 (4G/5G) Flörke / Kappert



Coagulation:

Prothrombin G20210A


Feb. (1)

08.11.19 15.01.20 14.02.20

June (3)

06.03.20 06.05.20 05.06.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 746 Set 01-F – Prothrombin G20210A Flörke / Kappert


Hereditary fructose intolerance:

Aldolase B: A 149 P Aldolase B: A 174 D Aldolase B: N 334 K


Feb. (1)

08.11.19 15.01.20 14.02.20

June (3)

06.03.20 06.05.20 05.06.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 793 Set 02-A – Aldolase B (A149P, A174D, N334K) Flörke / Kappert

Genetics 27/156



Enzyme inhibitors:

Alpha-1 antitrypsin S-Locus Alpha-1 antitrypsin Z-Locus


Feb. (1)

08.11.19 15.01.20 14.02.20

June (3)

06.03.20 06.05.20 05.06.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 743 Set 02-B – alpha1-Antitrypsin (PiM, PiS, PiZ) Flörke / Kappert



Lipoproteins:

Apo E (genotypes 2, 3, 4)


Feb. (1)

08.11.19 15.01.20 14.02.20

June (3)

06.03.20 06.05.20 05.06.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 744 Set 02-C – Apolipoprotein E (Genotypes 2, 3, 4) Flörke / Kappert


participation according to Rili-BÄK: yearly

M. Wilson:

ATP 7 B: H 1069 Q


Feb. (1)

08.11.19 15.01.20 14.02.20

June (3)

06.03.20 06.05.20 05.06.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 745 Set 02-D – Copper-Binding Protein: ATP7B (H1069Q) Flörke / Kappert



Haemochromatosis:

HFE: C 282 Y HFE: H 63 D HFE: S 65 C


Feb. (1)

08.11.19 15.01.20 14.02.20

June (3)

06.03.20 06.05.20 05.06.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 741 Set 02-E – HFE: H63D, C282Y (optional S65C) Flörke / Kappert

Genetics28/156



Hyperbilirubinaemia:

UDP-glucuronyl transferase (TA)6, (TA)7


Feb. (1)

08.11.19 15.01.20 14.02.20

June (3)

06.03.20 06.05.20 05.06.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 742 Set 02-F – UDP-Glucuronyltransferase 1 Flörke / Kappert

3 samples, DNA suspended in wateradditional sample not available

Antithrombin (AT3; SERPINC1) (3 exons as specified)


Feb. (1)

08.11.19 15.01.20 14.02.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 792 Set 03-A – Antithrombin (AT3; SERPINC1) Christensen / Kappert

3 samples, DNA (in 20 µl water) isolated from human leukocytes

Ret Proto-oncogene, exon 10-16


Feb. (1)

08.11.19 15.01.20 14.02.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 738Set 03-B – Ret Proto-Oncogene (Multiple Endocrine Neoplasia Type 2A – MEN2A)

Christensen / Kappert

3 samples, DNA suspended in wateradditional sample not available

Protein C(3 exons as specified)


Feb. (1)

08.11.19 15.01.20 14.02.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 790 Set 03-C – Protein C Christensen / Kappert

additional sample not available

Genetics 29/156

3 samples, DNA suspended in water additional sample not available

Protein S (3 exons as specified)


Feb. (1)

08.11.19 15.01.20 14.02.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 791 Set 03-D – Protein S Christensen / Kappert

2 samples of 20 µl DNA in Tris-EDTA


Lactase-Gene (LCT) (T -13910 C)



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 770 Set 01 – Lactase-gene (LCT) Maly / Fried



HLA DQA1*05 HLA DQB1*02 HLA DQB1*03:02



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 772 Set 03 – HLA-DQ Maly / Fried



Apo B 100 (R 3500 Q)



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 771 Set 02 – ApoB Maly / Fried

Genetics30/156



Cyp21A2 gene (Del 8bp) Cyp21A2 gene (E6 Cluster) Cyp21A2 gene (F306 +T) Cyp21A2 gene (I 172 N) Cyp21A2 gene (I2 G) Cyp21A2 gene (P 30 L) Cyp21A2 gene (P 453 S) Cyp21A2 gene (Q 318 X) Cyp21A2 gene (R 356 W) Cyp21A2 gene (V 281 L)



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 773 Set 04 – CYP21A2 21-Hydroxylase Maly / Fried


NOD2 (G 908 R) NOD2 (L 1007fs InsC) NOD2 (R 702 W)



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 774 Set 05 – NOD2 Maly / Fried



CYP2C19*2 Allele: G 681 A CYP2C19*3 Allele: G 636 A CYP2C9*2 Allele: C 430 T CYP2C9*3 Allele: A 1075 C TPMT (nt. A 719 G) TPMT (nt. G 460 A) TPMT*2 Allele (nt. G 238 C) VKORC1: C 1173 T VKORC1: G -1639 A



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 775 Set 06 – CYP2C9 CYP2C19 VKORC1 TPMT Maly / Fried

Genetics 31/156


K-ras Codon 12 mutation K-ras Codon 12 mutation type K-ras Codon 12/13 mutation K-ras Codon 13 mutation K-ras Codon 13 mutation type K-ras Codon 61 mutation K-ras Codon 61 mutation type



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 776 Set 07 – K-ras Codon 12/13/61 Maly / Fried



CYP2D6 Gene Duplication CYP2D6*3: A2637 del CYP2D6*4: G 1934 A CYP2D6*5: complete Deletion CYP2D6*6: T1795 del DPD (exon 14 skipping) IL-28B C/T: rs 12979860



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 777 Set 08 – CYP2D6 DPD IL28B Maly / Fried



CFTR gene (1078 del T) CFTR gene (1342-2 A>C) CFTR Gen (1677 delTA) CFTR gene (1717-1 G>A) CFTR Gen (2143 del T) CFTR gene (2183A A>G) CFTR Gen (2184 delA) CFTR gene (2184 ins A) CFTR gene (2789+5 G>A) CFTR gene (3272-26 A>G) CFTR gene (3659 del C) CFTR gene (3849+10kb C>T) CFTR Gen (3905insT) CFTR gene (394 del TT) CFTR gene (621+1 G>T) CFTR Gen (A455E) CFTR Gen (E 60 X) CFTR Gen (E 92 X) CFTR gene (G 542 X) CFTR gene (G 551 D) CFTR gene (G 85 E) CFTR gene (I 148 T) CFTR gene (I 336 K) CFTR gene (I 507 del) CFTR gene (Intron 8 (Polypyrimidine Tract)) CFTR gene (M 1101 K) CFTR gene (N 1303 K) CFTR gene (R 1162 X) CFTR gene (R 117 H) CFTR gene (R 334 W) CFTR gene (R 347 P) CFTR gene (R 553 X) CFTR gene (W 1282 X) CFTR gene (Y 1092 X (C>A)) CFTR gene (dele2,3 (21kb)) CFTR gene (delta F 508)



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 778 Set 09 – CFTR Common Mutations Maly / Fried

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

5.8

aurelijaz

Highlight

aurelijaz

Sticky Note

5.9

Genetics32/156



Dystrophin – mutation Dystrophin – mutation type



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 780 Set 11 – Dystrophin (Becker-Duchenne) Maly / Fried



Allele 1 FMR1 CGG repeats in 5’ UTR Allele 2 FMR1 CGG repeats in 5’ UTR Evaluation



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 781 Set 12 – FMR1 Fragile X Maly / Fried



GJB2 35del G (Connexin 26)



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 782 Set 13 – GJB2 Connexin 26 Maly / Fried



BRCA1 mutation BRCA1 mutation type BRCA2 mutation BRCA2 mutation type



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 779 Set 10 – BRCA1 BRCA2 Maly / Fried

aurelijaz

Highlight

aurelijaz

Sticky Note

5.10

Genetics 33/156



MLH1 mutation MLH1 mutation type MSH2 mutation MSH2 mutation type



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 783 Set 14 – MSH2 MLH1 (HNPCC) Maly / Fried

2 samples of 40 µl DNA in Tris-EDTA2


HTT Gen – evaluation allele 1 HTT Gen – evaluation allele 2 HTT Gen – CAG repeats allele 1 HTT Gen – CAG repeats allele 2



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 784 Set 15 – HTT Huntingtin Maly / Fried



SMN1 Gen – exon 7 deletion SMN1 Gen – exon 8 deletion



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 787 Set 17 – SMN1 (Spinal Muscular Atrophy) Maly / Fried



SNRPN gene – diagnosis SNRPN gene – maternal allele SNRPN gene – paternal allele



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 786 Set 16 – ANCR (Prader-Willi, Angelman) Maly / Fried

aurelijaz

Highlight

aurelijaz

Sticky Note

5.11

aurelijaz

Highlight

aurelijaz

Sticky Note

5.12

Genetics34/156



Y-Chromosome AZFa deletion Y-Chromosome AZFb deletion Y-Chromosome AZFc deletion



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 04.11.20

. 788 Set 18 – AZF (Y-Chromosome Microdeletions) Maly / Fried

2 DNA samples

CALR Exon 9 Mutation(s) CALR Specification



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 768 CALR Kreuzer / Kleinert


2 DNA samples

p.D816V



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 767 KIT Kreuzer / Kleinert

2 DNA samples

p.L265P



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 766 MYD88 Kreuzer / Kleinert

aurelijaz

Highlight

aurelijaz

Sticky Note

5.13

Genetics 35/156

2 DNA samples

STAT3 Exon 21 Mutation(s) STAT3 Nomenclature



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 769 STAT3 Kreuzer / Kleinert

2 DNA samples

TP53 Mutation(s) TP53 Nomenclature



Apr. (2)

10.01.20 04.03.20 01.04.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 765 TP53 Kreuzer / Kleinert

2 samples DNA

Report alpha-Globin – Evaluation alpha-Globin – Genotype alpha-Globin – Mutation 1 alpha-Globin – Mutation 2 alpha-Globin – Mutation 3 alpha-Globin – Mutation 4 beta-Globin – Evaluation beta-Globin – Genotype beta-Globin – Mutation 1 beta-Globin – Mutation 2 beta-Globin – Mutation 3 beta-Globin – Mutation 4


June (3)

06.03.20 06.05.20 05.06.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 794 Alpha-Globin and beta-Globin Frömmel / Méndez

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

5.7

Haematology36/156

HAEMATOLOGY

2 specimen of 2 ml, stabilized control blood


Analysis of Haemoglobin with HemoCue systems is possible!

Erythrocytes Haematocrit el.count Haematocrit centrif. Haemoglobin Leucocytes MCV Thrombocytes


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 211 Haematology 01 – Blood Cell Count Dorn-Beineke / Nebe

2 peripheral blood smears

In addition to the two preparations, you usually receive an additional and difficult preparation (free of charge) which is not part of the EQA scheme, but is only intended for educational purposes. participation according to Rili-

BÄK: quarterlyBlood Cell Differentiation in % Diagnostic comment Morphology of erys, leucos and platelets



Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

212 Haematology 07 – Blood Smear Analysis Diem / Baurmann

2 digital slides in a virtual microscope of bone marrow aspirateadditional sample not available

Evaluation and diagnosis


No samples will be sent!


Mar. (2)

10.01.20 04.03.20 18.03.20

Sep. (5)

26.06.20 26.08.20 09.09.20

. 218 Haematology 09 – Bone Marrow Cytology Haferlach / Gassmann

Haematology 37/156

2 samples of erythrocytes preparation, lyophilised

Haemoglobin (free)

The samples are not suitable for methods based on photometric measurements of the oxyhaemoglobin peaks around 540 nm and/or 577 nm. The Harboe method (415 nm peak) is not affected. The quantitative hemolysis index from automated chemistry analysers can also provide a suitable result.


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 236 Haematology 16 – Free Haemoglobin von Ahsen / Klouche

2 samples of control blood

participation according to Rili-BÄK: quarterlyHaematocrit centrif. Haemoglobin Leucocytes Thrombocytes


Mar. (2)

10.01.20 04.03.20 11.03.20

May (3)

06.03.20 06.05.20 13.05.20

July (4)

30.04.20 01.07.20 08.07.20

Oct. (6)

07.08.20 07.10.20 14.10.20

. 209 Haematology 03 – Blood Cell Count – QBC System Dorn-Beineke / Nebe

2 samples for automated reticulocyte counting by cell analysers


Jan. (1)

08.11.19 21.01.20 29.01.20

May (3)

13.03.20 12.05.20 20.05.20

Sep. (5)

10.07.20 08.09.20 16.09.20

Oct. (6)

14.08.20 13.10.20 21.10.20

. 216 Haematology 04 – Reticulocyte Analysis 02 (Machine-Based Analysis) Nebe / Gutensohn

2 samples of fresh whole blood from blood bank, overnight shipping


Basophilic Granulocytes Eosinophilic Granulocytes Erythrocytes Haematocrit el.count Haematocrit centrif. Haemoglobin large unstained cells Leucocytes Lymphocytes MCV Monocytes Neutrophilic Granulocytes Thrombocytes immature granulocytes

Due to high demand two different sets of samples will be sent (Gr. 612 = Gr. 912). The group number you receive will be set by INSTAND e.V. before each EQAS shipment. Both groups are equivalent.


Jan. (1)

08.11.19 21.01.20 29.01.20

May (3)

13.03.20 12.05.20 20.05.20

Sep. (5)

10.07.20 08.09.20 16.09.20

Oct. (6)

14.08.20 13.10.20 21.10.20

. 612 Haematology 06 – Differential Blood Count (Machine-Based Analysis) Dorn-Beineke / Nebe

Haematology38/156

2 samples, cellular products

For flow cytometric determination of T, B and NK cells in cellular products only



May (3)

13.03.20 12.05.20 20.05.20

Oct. (6)

14.08.20 13.10.20 21.10.20

. 617Haematology 14 – Immunophenotyping 03 (T, B and NK cells in cellular products)

Humpe / Gutensohn

2 samples, control blood


Lymphocyte-immunophenotyping – peripheral blood:

B-Lymphocytes CD4 pos. lymphocytes with CD3-expression (%) CD4 pos. lymphocytes with CD3-expression (/nl) CD8 pos. lymphocytes with CD3-expression Leucocytes Lymphocytes NK-cells without CD3-expression T-Lymphocytes



Mar. (2)

10.01.20 10.03.20 18.03.20

Sep. (5)

10.07.20 08.09.20 16.09.20

. 213 Haematology 10 – Immunophenotyping 01 Kern / Schabath

2 blood smears for microscopic analysis


Jan. (1)

08.11.19 21.01.20 29.01.20

July (4)

08.05.20 07.07.20 15.07.20

. 215 Haematology 05 – Reticulocyte Analysis 01 (Microscopy) Nebe / Gutensohn

2 samples, human blood

For flow cytometric determination of CD34+ stem and progenitor cells; vitality measurements


Jan. (1)

08.11.19 21.01.20 29.01.20

Mar. (2)

10.01.20 10.03.20 18.03.20

July (4)

08.05.20 07.07.20 15.07.20

Sep. (5)

10.07.20 08.09.20 16.09.20

. 217 Haematology 11 – Stem/Progenitor Cells (CD 34) Gutensohn / Humpe

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.17 Hematologija 10 - Imunofenotipavimas 01

aurelijaz

Sticky Note

Limfocitų imunofenotipavimas periferiniame kraujyje

Haematology 39/156

Sample I and II: bone marrow or blood smears and leukaemia or lymphoma cells

Immunophenotyping of leukamiaes/lymphomas

Immunophenotyping of Hematologic Neoplasms



Mar. (2)

10.01.20 10.03.20 18.03.20

Sep. (5)

10.07.20 08.09.20 16.09.20

. 214 Haematology 12 – Immunophenotyping 02 Schabath / Kern

2 samples, EDTA blood

GPI-deficient cells

Due to high demand 3 different sets of samples will be sent (No. 616 = No. 916 or No. 917). The group number you receive will be set by INSTAND e.V. before each EQAS shipment. All groups are equivalent!


May (3)

06.03.20 05.05.20 20.05.20

Oct. (6)

07.08.20 06.10.20 21.10.20

. 616 Haematology 13 – PNH Diagnostics Höchsmann / Nebe

2 samples of whole bloodadditional sample not available

Evaluation and diagnosis


June (3)

06.03.20 06.05.20 05.06.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 210 Haematology 15 – Haemoglobinopathies Frömmel / Méndez

Haemostasis40/156

HAEMOSTASIS

2 samples of 1 ml plasma, lyophilised

Maximum order: 2 sets of samples


Global test I: PT (PTZ, Quick), aPTT

No. 221 is only for measuring in plasma samples. For measurements of whole blood in POCT systems, please register for No. 286!


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 221 Haemostasis 01 – TPT, INR, aPTT Spannagl / Dick


Maximum order: 2 sets of samplesGlobal test II: TZ, FIB, FSP screening FSP screening, using batroxobin time or heparin-independent thrombin time


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 222 Haemostasis 02 – FIB, TZ, FSP Spannagl / Dick


Maximum order: 2 sets of samplesSingle factors A (via PT): factor II, factor V, factor VII, factor X


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 223 Haemostasis 03 – Factor II, V, VII,X Spannagl / Dick


Maximum order: 2 sets of samplesSingle factors B (via APTT, etc.): factor IX, factor XI, factor XII, factor XIII


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 224 Haemostasis 04 – Factor IX, XI, XII, XIII Spannagl / Dick

Haemostasis 41/156


Maximum order: 2 sets of samplesInhibitors (AT, PC, PS)

Antithrombin C1-Inhibitor Total Protein C Protein S total Free Protein S funct. (act.) Free Protein S immun. (conc.)


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 225 Haemostasis 05 – AT, Protein C, Protein S, C1-Inhibitor Spannagl / Dick

2 samples of 0.5 ml or 1 ml plasma, lyophilised

Maximum order: 2 sets of samplesD-Dimer (qualitative) D-Dimer (quantitative)


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 226 Haemostasis 06 – D-Dimer Spannagl / Peetz / Dick


Maximum order: 2 sets of samplesFactor VIII akt. Willebrand fact. Ag Willebrand fact. activity Willebrand fact. CBA Willebrand fact. RiCof


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 227 Haemostasis 07 – Factor VIII, WF Spannagl / Dick


Maximum order: 2 sets of samplesArgatroban Thrombin time aPTT


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 230 Haemostasis 10 – Argatroban Peetz / Spannagl / Dick

Haemostasis42/156


Maximum order: 2 sets of samplesThrombin time UF Heparin aPTT


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 280 Haemostasis 12 – UF Heparin Peetz / Spannagl / Dick


Maximum order: 2 sets of samplesLMW Heparin


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 281 Haemostasis 13 – LMW Heparin Peetz / Spannagl / Dick


Maximum order: 2 sets of samplesOrgaran


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 282 Haemostasis 14 – Orgaran Peetz / Spannagl / Dick


Maximum order: 2 sets of samplesExtrinsic: A20 [mm] Extrinsic: CT[s] r[min] Intrinsic: A20 [mm] Intrinsic: CT[s] r[min]


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 283 Haemostasis 15 – TEG/ROTEM Spannagl / Dick

Haemostasis 43/156




Antithrombin D-Dimer (quantitative) Fibrinogen PTZ, Quick TPZ INR Thrombin time aPTT


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 285 Haemostasis 17 – Compact Spannagl / Dick


Functional APC resistance

APC resistance Diagnostic comments


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 288 Haemostasis 20 – Functional APC Resistance Spannagl / Dick


Maximum order: 2 sets of samplesFondaparinux


May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 501 Haemostasis 21 – Fondaparinux Peetz / Spannagl / Dick


Maximum order: 2 sets of samplesDabigatran


May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 502 Haemostasis 22 – Dabigatran Peetz / Spannagl / Dick

aurelijaz

Highlight

aurelijaz

Sticky Note

2.26 Hemostazė 17 - Compact

Haemostasis44/156


Maximum order: 2 sets of samplesRivaroxaban


May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 503 Haemostasis 23 – Rivaroxaban Peetz / Spannagl / Dick


Maximum order: 2 sets of samplesApixaban


May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 504 Haemostasis 25 – Apixaban Peetz / Spannagl / Dick

2*3 samples of 1 ml plasma, lyophilised

Maximum order: 2 sets of samplesExtrinsic: A20 [mm] Extrinsic: CT[s] r[min] Intrinsic: A20 [mm] Intrinsic: CT[s] r[min]

Participation only for device Rotem Sigma!


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 509 Haemostasis 31 – ROTEM Sigma Spannagl / Dick


Maximum order: 2 sets of samplesEdoxaban


May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 505 Haemostasis 32 – Edoxaban Peetz / Spannagl / Dick

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.27 Hemostazė 31 - ROTEM Sigma

Haemostasis 45/156

2 samples of whole blood



Due to different detection techniques that are applied, not every sample material can be guarenteed to be suitable for every POCT machine. The machine microINR by the company Axon Lab is not suitable for this EQAS!

ACT PTZ, Quick TPZ INR aPTT



Jan. (1)

13.12.19 21.01.20 23.01.20

May (3)

03.04.20 12.05.20 14.05.20

Sep. (5)

31.07.20 08.09.20 10.09.20

Nov. (6)

25.09.20 03.11.20 05.11.20

. 286 Haemostasis 18 – POCT Giebl / Spannagl

1 sample of plasmaadditional sample not available

Lupus anticoagulant


Samples and evaluation by ECAT, Voorschoten, Netherlands. Only annual subscription possible! An evaluation by INSTAND e.V. does not take place and is not part of the accreditation of INSTAND e.V.!

Please note: Cancelation of the order will not be possible with the end of the registration date!


This EQAS will be carried out on four dates with sample dispatch on March 10th, 2020, May 26th 2020, August 25th, 2020 and November 3th, 2020. The deadline for registration ends on Decem-ber 9th, 2019.

. 228 Haemostasis 08 – Lupus Anticoagulant Spannagl / Dick

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.25 Hemostazė 18 - (POCT)

aurelijaz

Highlight

Haemostasis46/156

2 samples of plasmaadditional sample not available

Factor VIII Inhibitor


Samples and evaluation by ECAT, Voorschoten, Netherlands. Only annual subscription

possible!

An evaluation by INSTAND e.V. does not take place and is not part of the accreditation of

INSTAND e.V.! Please note: Cancelation of the order will not be possible with the end of the

registration date! EQA results can only be submitted online!

This EQAS will be carried out on two dates with sample dispatch on May 26th, 2020 and November 3th, 2020. The deadline for registration ends on December 9th, 2019.

. 220 Haemostasis 11 – Factor VIII Inhibitor Spannagl / Dick


Different quantity on detection of antibodies or functional test.


Samples and evaluation by ECAT, Voorschoten, Netherlands. Only annual subscription

possible!



registration date! EQA results can only be submitted online!

This EQAS will be carried out on one date with sample dispatch on August 25th, 2020. The deadline for registration ends on December 9th, 2019.

. 287 Haemostasis 19 – HIT-I (Immunological Testing) Spannagl / Kiefel

Haemostasis 47/156


Thrombin generation test


Samples and evaluation by ECAT, Voorschoten, Netherlands. Only annual subscription possible!



registration date!


This EQAS will be carried out on two dates with sample dispatch on May 26th, 2020 and Novem-ber 3th, 2020. The deadline for registration ends on December 9th, 2019.

. 289 Haemostasis 24 – Thrombin Generation Test Spannagl / Dick


ADAMTS13 (activity and antigen)


Samples and evaluation by ECAT, Voorschoten, Netherlands. Only annual subscription possible! An evaluation by INSTAND e.V. does not take place and is not part of the accreditation of INSTAND e.V.!

Please note: Cancelation of the order will not be possible with the end of the registration date!


This EQAS will be carried out on four dates with sample dispatch on March 10th, 2020, May 26th, 2020, August 25th, 2020 and November 3th 2020. The deadline for registration ends on Decem-ber 9th 2019.

. 510 Haemostasis 26 – ADAMTS13-I (Activity/Antigen) Spannagl / Dick

Haemostasis48/156

2 samples of plasma additional sample not available

ADAMTS13 (Antibodies)





registration date!


This EQAS will be carried out on two dates with sample dispatch on May 26th, 2020 and Novem-ber 3th, 2020. The deadline for registration ends on December 9th, 2019.

. 511 Haemostasis 27 – ADAMTS13-II (Antibodies) Spannagl / Dick


Factor IX Inhibitor





registration date!


This EQAS will be carried out on two dates with sample dispatch on March 10th, 2020 and August 25th, 2020. The deadline for registration ends on December 9th, 2019.

. 514 Haemostasis 30 – Factor IX Inhibitor Spannagl / Dick

Haemostasis 49/156

In cooperation with ECAT, Voorschoten, Netherlands. Only available in German! International version available at www.ecat.nl

An evaluation by INSTAND e.V. does not take place and is not part of the accreditation of INSTAND e.V.!


. 512 Haemostasis 28 – Bleeding Disorder Case Study Spannagl / Dick

In cooperation with ECAT, Voorschoten, Netherlands. Only available in German! International version available at www.ecat.nl


. 513 Haemostasis 29 – DNA for EQAS 512 (optional) Spannagl / Dick

Clinical Chemistry and Laboratory Medicine50/156

CLINICAL CHEMISTRY AND LABORATORY MEDICINE

2 samples of 0,5 ml serum, liquid, stabilzedadditional sample not available

ACE


Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 630 ACE (Angiotensin-Converting-Enzyme) Durner / N.N.

2 samples of serum, lyophilised

Asialotransferrin Carbohydrate-deficient transferrin+Asialotransferrin Disialotransferrin


Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 750 Markers of Ethanol Abuse 01 Luppa / Schneider

2 samples of 1 ml urine, lyophilised

Ethylglucuronid


Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 751 Markers of Ethanol Abuse 02 Luppa / Schneider

Clinical Chemistry and Laboratory Medicine 51/156

2 samples of 1 ml, plasma, lyophilised

4-Hydroxyproline (free) Alanine Arginine Argininosuccinic acid Asparagine Aspartic acid Interpretation of results Citrulline Cystathionine Cysteine-Homocysteine-disulfide Cystine Glutamine Glutamic acid Glycine Histidine Isoleucine Leucine Lysine Methionine Ornithine Phenylalanine Phosphoethanolamine Proline Sarcosine Serine Taurine Threonine Tryptophan Tyrosine Valine allo-Isoleucine alpha-Aminoadipic acid b-Alanine



May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 710 Amino Acid Analysis N.N. / Schadewaldt

2 samples of 1 ml, liquid controls

Ammonia


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 118 Ammonia Falck / Nauck

2 samples of 0.4 ml, serumadditional sample not available


C-reactive protein (qualitative) C-Reactive Protein (quantitative)


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 322 Infection Serology – C-Reactive Protein Hunfeld / N.N.

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.19 Amoniakas


2 samples of plasma

Epinephrine Dopamine Norepinephrine Serotonin


Mar. (2)

10.01.20 04.03.20 18.03.20

Sep. (5)

26.06.20 26.08.20 09.09.20

. 185 Biogenic Amine in Plasma Schneider / Luppa

2 samples of 2 ml serum / plasma, lyophilised


CK-MB (activity) CK-MB (mass) CK-MB (qualitative) Myoglobin Myoglobin (qualitative) NT-pro BNP Troponin I Troponin I (qualitative) Troponin T Troponin T (qualitative)


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 760 Myocardial Markers Baum / Peetz

2 samples serum / plasma, lyophilised

BNP


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 761 Myocardial Markers BNP Baum / Peetz

2 samples of 5 ml serum, lyophilised


Albumin Albumin (electrophoresis) Protein a1-Globulins a2-Globulins beta-Globulins gamma-Globulins


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 141 Serum Proteins/Electrophoresis Niederau / Schellenberg

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.22 Miokardo žymenys BNP

aurelijaz

Highlight

aurelijaz

Sticky Note

2.23 Miokardo žymenys

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

Troponinas I, Troponinas I (kokybinis)



Fructosamine


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 146 Fructosamine Niederau / Kaiser

2 fecal samples of 0.5-1 ml, lyophilisedadditional sample not available

Calprotectin Calprotectin (qualitative) Fecal elastase Fecal elastase (qualitative)


Mar. (2)

10.01.20 04.03.20 18.03.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 130 Fecal Diagnostics 01 Durner / Spannagl

2 fecal samples of 0.5-1 ml, lyophilisedadditional sample not available

Haemoglobin Haemoglobin (qualitative) Hemoglobin-Haptoglobin-complex Hemoglobin-Haptoglobin-complex (qualitative)


Mar. (2)

10.01.20 04.03.20 18.03.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 131 Fecal Diagnostics 02 Durner / Spannagl

2 samples of 2 ml, serum or plasma

participation according to Rili-BÄK: quarterlyEthanol


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 700 Ethanol Schellenberg / Falck

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.1 Išmatų diagnostika 02

aurelijaz

Highlight

aurelijaz

Sticky Note

Hemoglobinas, Hemoglobinas (kokybinis)Hemoglobino-Haptoglobino kompleksas, Hemoglobino-Haptoglobino kompleksas (kokybinis)


2 samples of 1 ml, plasma

Free light chains type kappa (quantitative) Free light chains type lambda (quantitative) Gammopathies IgA IgG IgM kappa/lambda (ratio)


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 243 Gammopathies Peetz / Niederau


participation according to Rili-BÄK: quarterlyGlucose


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 111 Glucose – Conventional Analysis Niederau / Falck

2 samples of pulverized material


May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 500 Urinary Stone Analyses Neubeck / Reuner

2 samples of 1 ml, serum

IgG1 IgG2 IgG3 IgG4


May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 244 IgG Subclasses Schellenberg / Falck




AP Albumin Albumin (electrophoresis) Aldolase Bilirubin Bilirubin conj. CK Calcium Chloride Cholesterol CHE Iron binding capacity Iron Protein GGT GLDH GOT GPT Acid phosphatase Glucose HBDH Urea Uric Acid IgA IgG IgM Potassium Creatinine Copper LDH Lactate Lipase Lithium Magnesium Sodium Osmolality Pancreas amylase Phosphate Prostatic acid Posphatase Transferrine Triglycerides alpha-Amylase gamma-Globulins


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 100 Clinical Chemistry – Conventional Analysis Falck / Niederau



Apolipoprotein A1 Apolipoprotein B Apolipoprotein E Cholesterol HDL-cholesterol Homocystein LDL-cholesterol Lp (a) Phospholipids Triglycerides


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 151 Lipids/Lipoproteins Niederau / N.N.

2 samples of serum (liquid)

Albumin (electrophoresis) a1-Globulins a2-Globulins beta-Globulins gamma-Globulins


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 102 Capillary Zone Electrophoresis Niederau / Schellenberg


2 samples serum of 2 ml, lyophilised

participation according to Rili-BÄK: quarterlyNeonatal Bilirubin


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 110 Neonatal Bilirubin Niederau / Falck

2 samples of potassium picrate solution

Wavelengths 334, 340, 365, 405 and 436 nm


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 181 Photometer Controls Kaiser / Kramer



C3-Complement C4-Complement C-Reactive Protein (quantitative) Coeruloplasmin Ferritin Haptoglobin Hemopexin IGE IgA IgG IgM sTfR Transferrine a1-Antitrypsine a1-Glycoprotein a2-Makroglobulin


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 241 Plasmaproteins 01 Schellenberg / Falck

2 samples, serumadditional sample not available

Cystatine-C


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 242 Plasmaproteins 02 – Cystatin-C Schellenberg / Falck


2 samples of serum


AFP beta-2-Microglobulin CA 125 CA 15-3 CA 19-9 CA 72-4 CEA CYFRA 21-1 HE4 HER2/new NSE PSA, free PSA, total ROMA-Score S100 SCC TPA TPS Thyreoglobulin hCG intact hCG intact +beta-hCG free


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 292 Tumor Markers Holdenrieder / Peetz

2 samples of serum

Calcitonin Progastrin-releasing Peptide


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 299 Tumor Markers – Calcitonin/Pro-Gastrin-Releasing Peptide Holdenrieder / Peetz

2 samples of serum

participation according to Rili-BÄK: quarterlyPSA, free PSA, total Testosterone


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 293 Tumor Markers – PSA and Testosterone Holdenrieder / Peetz

2 samples, serumadditional sample not available

hsCRP


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 240 Plasmaproteins 03 – hsCRP Schellenberg / Falck



1,25-OH Cholecalciferol 25-OH CCF (Vitamin D) Biotin (Vitamin H) Cobalamin (Vitamin B12) Folic acid Holotranscobalamine Pantothenic acid (Vitamin B5) Pyridoxal-5-phosphate (Vitamin B6) Retinol (Vitamin A) Riboflavin (Vitamin B2) Thiamine total (Vitamin B1) Tocopherol (Vitamin E)


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 290 Vitamins 01 (Serum) Niederau / Schellenberg

2 samples of 2 ml haemolysates, lyophilised

Flavine Adenine Dinucleotide (FAD) Flavine mononucleotid (FMN) Pyridoxal-5-phosphate (Vitamin B6) Riboflavin (Vitamin B2) Thiamine total (Vitamin B1) Thiaminpyrophosphat (TPP)


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 291 Vitamins 02 (Whole Blood) Niederau / Schellenberg

2 samples of 0,5 ml plasma

Ascorbic acid (Vitamin C)


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 296 Vitamins 03 – Vitamin C Niederau / Schellenberg


Methylmalonic acid


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 187 Vitamins 04 – Methylmalonic Acid Niederau / Schellenberg


2 samples of 1 ml serum (lyophilised)

Maximum order: 3 sets of samplesAlternative pathway C1 inhibitor: activity C1 inhibitor: proteine C1q proteine C3-Complement C4-Complement Classical pathway Complement factor H Complement factor I Lectin pathway

Anaylsis of the total function of the 3 complement activation pathways (classical, alternative and lectin pathways) either by functional ELISA (WIELISA), by haemolytic (CH50, AH50) or by liposome-based assay (CH50). Participation with one parameter (e.g. CH50) is possible.


Apr. (2)

10.01.20 04.03.20 03.04.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 246 Complement Analysis 02 (Functions and proteins) Prohaszka / Kirschfink

2 samples of 500 µl plasma (lyophilised)

Maximum order: 3 sets of samplesC3a, C3d, Bb, sC5b-9


Nov. (6)

07.08.20 07.10.20 06.11.20

. 247 Complement Analysis 03 (Complement activation products) Prohaszka / Kirschfink

2 samples of 150 µl serumadditional sample not available

C3-nephritic factor (qualitative) C3-nephritic factor (quantitative)


Nov. (6)

07.08.20 07.10.20 06.11.20

. 248 Complement Analysis 04 (C3 – nephritic factor) Prohaszka / Kirschfink


Auto-anti C1q (IgG) Auto-anti C1q (IgG) (qualitative)


Apr. (2)

10.01.20 04.03.20 03.04.20

Nov. (6)

07.08.20 07.10.20 06.11.20

. 245 Complement Analysis 01 (Auto-anti-C1q) Prohaszka / Kirschfink



Auto-anti FH-(qualitative) Auto-anti-FH (quantitative)


Nov. (6)

07.08.20 07.10.20 06.11.20

. 249 Complement Analysis 05 (Auto-anti FH) Prohaszka / Kirschfink


Auto-anti-C1 inhibitor IgA (qualitative) Auto-anti-C1 inhibitor IgA (quantitative) Auto-anti-C1 inhibitor IgG (qualitative) Auto-anti-C1 inhibitor IgG (quantitative) Auto-anti-C1 inhibitor IgM (qualitative) Auto-anti-C1 inhibitor IgM (quantitative)


Nov. (6)

07.08.20 07.10.20 06.11.20

. 250 Complement Analysis 06 (anti – C1 inhibitor) Prohaszka / Kirschfink

2 samples of EDTA whole blood, 0.3 ml (not stabilized)


HbA1c

The samples must be measured within 2 days of receipt!


Jan. (1)

08.11.19 21.01.20 24.01.20

Mar. (2)

24.01.20 24.03.20 27.03.20

May (3)

13.03.20 12.05.20 15.05.20

July (4)

08.05.20 07.07.20 10.07.20

Sep. (5)

17.07.20 15.09.20 18.09.20

Oct. (6)

28.08.20 27.10.20 30.10.20

. 145 HbA1c Kaiser / Kramer

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.15 HbA1c

Trace Elements 61/156

TRACE ELEMENTS

2 samples of 10 ml, urine, lyophilised

Aluminium Arsenic Lead Chromium Iron Fluoride Iodine Cadmium Cobalt Copper Manganese Nickel Mercury Selenium Zinc


Mar. (2)

10.01.20 04.03.20 25.03.20

Oct. (6)

07.08.20 07.10.20 28.10.20

. 205 Trace Elements 01 (Urine) Kaiser / Kramer

2 samples of 5 ml, plasma, lyophilised

Aluminium Arsenic Chromium Iron Fluoride Gold Iodine Cadmium Cobalt Copper Manganese Nickel Platin Selenium Zinc


Mar. (2)

10.01.20 04.03.20 25.03.20

Oct. (6)

07.08.20 07.10.20 28.10.20

. 206 Trace Elements 02 (Plasma) Kaiser / Kramer

2 samples of 5 ml, serum, lyophilised

Antimon Beryllium Bismuth Molybdaen Vanadium Tin


Mar. (2)

10.01.20 04.03.20 25.03.20

Oct. (6)

07.08.20 07.10.20 28.10.20

. 207 Trace Elements 03 (Serum) Kaiser / Kramer

2 samples of 5 ml whole blood, lyophilised

Antimon Arsenic Lead Chromium Cadmium Cobalt Magnesium Manganese Nickel Mercury Selenium Zinc


Mar. (2)

10.01.20 04.03.20 25.03.20

Oct. (6)

07.08.20 07.10.20 28.10.20

. 208 Trace Elements 04 (Whole Blood) Kaiser / Kramer

Hormones62/156

HORMONES

2 samples of serum

Aldosterone


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 304 Hormones – Aldosterone Luppa / Schneider


1-84 PTH Calcitonin Thyreoglobulin


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 301 Hormones – Calcium Metabolism / Special Thyroid Durner / Luppa


participation according to Rili-BÄK: quarterlyanti-Mullerian hormone FSH LH


Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 297 Hormones – Fertility Maly / Lutz

2 samples of 3 or 5 ml serum / plasma, lyophilised

1-39 ACTH DHEA DHEA-S HGH Prolactin(3.IS)


Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 298 Hormones – Adrenal Gland/Pituitary Luppa / Schneider

Hormones 63/156


C-Peptide Gastrin Glucagon Insulin Pro-insuline


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 300 Hormones – Pancreas/Gastrointestinal Tract Durner / Luppa

2 samples of 5 ml of serum / plasma, lyophilised

participation according to Rili-BÄK: quarterlyT3total T4total(thyroxine) TSH free T3 free T4


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 294 Hormones – Thyroid Hormones Durner / Luppa

2 samples of 1 ml of serum / plasma, lyophilised

anti-mikrosomen anti-TPO anti-tyreoglobulin TRAK/THYBIA


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 295 Hormones – Thyroid Gland Antibodies Durner / Luppa



17-beta-Estradiol Cortisol T3total T4total(thyroxine)Progesterone TSH Testosterone free T3 free T4


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 302 Hormones – Steroid Homones, Thyroid Gland Luppa / Schneider

Hormones64/156

2 samples of serum / plasma

17-Hydroxyprogesterone Androstendion


Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 309 Hormones – Virilization Maly / Lutz


participation according to Rili-BÄK: quarterlyFree beta-chain hCG PAPP-A


Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 305 Hormones – Gravidity – 1st Trimester Screening Maly / Lutz


participation according to Rili-BÄK: quarterlyAFP hCG intact hCG intact +beta-hCG free


Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 306 Hormones – Gravidity – 2nd Trimester Screening Maly / Lutz

2 samples of 1 ml serum, lyophilisedadditional sample not available

Erythropoietin Thrombopoietin


May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 626 Hematopoetic Growth Factors Wenzel / Geisen

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.15 Hormonai - Nėštumas - 1-ojo trimestro tyrimas

aurelijaz

Sticky Note

2.16 Hormonai - Nėštumas - 2-ojo trimestro tyrimas

aurelijaz

Highlight

Hormones 65/156

2 samples of 1 ml serum, lyophilisedadditional sample not available

PLGF(placentalgrowthfactor)sFLT-1(solublefms-liketyrosinekinase-1)


May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 625 Preeclampsia Marker Luppa / Schneider

CSF66/156

CSF

2 sets = CSF + serumadditional sample not available


(Evaluation of CSF/serum quotients in diagrams and age-related interpretation)

Albumin Albumin – CSF Protein – CSF IgA IgA – CSF IgG IgG – CSF IgM IgM – CSF

Sample volumes in the CSF proficiency tests (No. 460-466) are limited as it is difficult to acquire large volumes of CSF.



Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 460 Cerebrospinal Fluid Analysis 01 – Protein Analysis Uhr / Zimmermann / Reiber

1 set of samples, CSF + serumadditional sample not available


(paired analysis of samples and interpretation)

Interpretation of the report Oligoclonal IgG

The acquisition of samples is demanding, as it is not possible to use pooled CSF, i.e. the samples are from individual patients (catheter, drainage, etc.).



May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 462 Cerebrospinal Fluid Analysis 02 – Oligoclonal IgG Uhr / Zimmermann / Reiber


Antibodies against Measles viruses, Rubella viruses, Varicella zoster viruses, Herpes simplex viruses (1+2). Analysis of virus-specific antibodies in CSF and serum for detection of specific antibody response in central nervous system (MRZ reaction).

Detection of titers is not suitable. Evaluation as antibody index and interpretation of combined data.



May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 463 Cerebrospinal Fluid Analysis 03 – MRZ Reaction Uhr / Zimmermann / Reiber

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.24 Cerebrospinalinio skysčio analizė 02 - Oligokloninis IgG

CSF 67/156

2 samples of 0.5 mladditional sample not available


Glucose – diagnostic comment Glucose quotient (CSF/Serum) Glucose quotient – diagnostic comment Glucose – CSF Interpretation of the report Lactate – CSF Lactate – diagnostic comment

Calculation of the CSF/serum ratio of glucose. Interpretation with respect to the reference range.



Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 464 Cerebrospinal Fluid Analysis 04 – Lactate/ Glucose Uhr / Zimmermann / Reiber



Borrelia IgG Antibody Index (AI) calculation Interpretation of the report

Detection of titers is not suitable. Calculation of antibody index and interpretation.



May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 465 Cerebrospinal Fluid Analysis 05 – Neuroborreliosis Zimmermann / Uhr

1 CSF sampleadditional sample not available

Amyloid ß Peptid 40 (Aß40) Amyloid ß Peptid 42 (Aß42) Amyloid ß Peptid Ratio (Aß 42/40) Total Tau Protein (Tau) PhosphoTau Protein (pTau)

Neurochemical dementia diagnostics: Support for differential diagnosis of dementia by interpretation of the combined analysis of different marker proteins in CSF.



May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 466 Cerebrospinal Fluid Analysis 06 – Dementia Markers Uhr / Zerr / Reiber

TDM / Drugs of Abuse Testing68/156

TDM / DRUGS OF ABUSE TESTING


Paracetamol Salicylic acid


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 194 Paracetamol and NSAIDs Steimer / Schneider


Amiodarone Desethylamiodarone


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 190 Antiarrhytmics – Amiodaron Steimer / Schneider

2 samples of 2.5 ml serum, lyophilised

Caffeine


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 870 Respiratory Stimulants – Caffeine Steimer / Schneider


Teicoplanin


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 193 Antibacterials – Teicoplanin Steimer / Schneider

TDM / Drugs of Abuse Testing 69/156


Ampicillin Cefepime Ceftazidime Linezolid Meropenem Piperacilline Sulbactam Tazobactam


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 890 Antibacterials 02 Schneider / Steimer


Lamotrigine Levetiracetam Sulthiame


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 191 Anticonvulsants 01 Steimer / Schneider


10-OH-Carbamazepine Carbamazepine-epoxide N-Desmethylmethsuximide


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20



Eslicarbazepine Felbamate Lacosamide Rufinamide


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20




Gabapentin Pregabalin Tiagabine Topiramate Vigabatrin Zonisamide


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20


2 samples of 5 ml serum, lyophilised (+ 2 samples of 3 ml antibiotics)

Chloramphenicol Fluconazole Flucytosine Posaconazole Voriconazole


May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 198 Antifungals / Chloramphenicol Steimer / Schneider


Hydroxy-Itraconazole Itraconazole Mycophenolic acid


Mar. (2)

10.01.20 04.03.20 18.03.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 602 Antifungals / Immunosuppressants von Ahsen / Kaiser


Clozapine N-Desmethylclozapine


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 200 Antipsychotic Drugs 01 Steimer / Schneider



Amisulpride Desmethyl sertraline Fluvoxamine Levomepromazine Pipamperone Reboxetine Sertraline Ziprasidone


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20



Desmethyl fluoxetine Fluoxetine Mianserine Perazine


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20



Chlorprotixene Desmethyl olanzapine Olanzapine Paroxetine


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20


2 samples of 1 – 3 ml, serum, lyophilised

We will inform you in time about the current parameters for the determination from the list below.

Atazanavir Darunavir Dolutegravir Efavirenz Elvitegravir Etravirine Lopinavir Maraviroc Nevirapine Raltegravir Ribavirine Rilpivirin Ritonavir


Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 850 Antivirals Schneider / Steimer



Alprazolam Chlordiazepoxide Desalkylflurazepam Diazepam Nordiazepam Oxazepam Trazodone


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 876 Benzodiazepines 01 Steimer / Schneider


Clonazepam Flunitrazepam Flurazepam Nitrazepam Temazepam


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20



Bromazepam Clobazam (Clobazepam) Lorazepam


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20


3 samples of whole blood, lyophilised.

Cyclosporine A Everolimus Sirolimus Tacrolimus


Mar. (2)

10.01.20 04.03.20 18.03.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 601 Immunosuppressants von Ahsen / Kaiser




Carbamacepine Digoxin Ethosuximid Lithium Phenobarbital Phenytoin Primidon Theophylline Valproic Acid


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 195 TDM 01 Steimer / Schneider / Kaiser



Amicacin Digitoxin Gentamicin Methotrexate Tobramycin Vancomycin


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 197 TDM 02 Steimer / Schneider / Kaiser

2 samples of 5 ml serum

10-OH-Carbamazepine Aripiprazole Citalopram Lamotrigine O-Desmethylvenlafaxine Perazine Quetiapine Venlafaxine


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 860 Psychotherapeutic Drugs 01 Haen / Ridders


Amisulpride Escitalopram Mirtazapine O-Desmethylvenlafaxine Quetiapine Venlafaxine


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20




9-OH-Risperidone / Paliperidone Clozapine Duloxetine Haloperidol N-Desmethylclozapine Olanzapine Quetiapine Risperidone Ziprasidone


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20



Amitriptyline Clomipramine Clozapine Desipramine Doxepin Imipramine Maproptiline N-Desmethylclozapine Norclomipramine Nordoxepin Nortriptyline Trimipramine


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20



Atomoxetine Methylphenidate Ritalinic acid


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 879 Psychostimulants – ADHS-Treatment Steimer / Schneider

2 samples of 2,5 ml serum, lyophilised

Desipramine Imipramine Maproptiline Normaproptiline Tricyclic Antidepressants – Screen


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 202 Tri-/Tetracyclic Antidepressants 03 – Quantitative in Serum Steimer / Schneider



Amitriptyline Clomipramine Norclomipramine Nortriptyline Tricyclic Antidepressants – Screen


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 199 Tricyclic Antidepressants 01 – Quantitative in Serum Steimer / Schneider


Doxepin Nordoxepin Nortrimipramine Trimipramine Tricyclic Antidepressants – Screen


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 201 Tricyclic Antidepressants 02 – Quantitative in Serum Steimer / Schneider



May contain the following substances:

Amitriptyline Clomipramine Desipramine Doxepin Imipramine Norclomipramine Nordoxepin Nortrimipramine Nortriptyline Trimipramine Tricyclic Antidepressants (qualitative)- Screening


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 203 Tricyclic Antidepressants 04 – Qualitative in Serum Steimer / Schneider



May contain the following substances:

Amitriptyline Clomipramine Desipramine Doxepin Imipramine Norclomipramine Nordoxepin Nortrimipramine Nortriptyline Trimipramine Tricyclic Antidepressants (qualitative)- Screening


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 204 Tricyclic Antidepressants 05 – Qualitative in Urine Steimer / Schneider




Amphetamine (qualitative) Amphetamine (quantitative) Barbiturate-phenobarbiturate (qualitative) Barbiturate-phenobarbiturate (quantitative) Benzoylecgonine (qualitative) Benzoylecgonine (quantitative) Opiate / Morphin (qualitative) Opiate / Morphin (quantitative)


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 174 Drugs of Abuse in Human Urine 01 (Qualitative+Quantitative) Steimer / Niederau



(d-)Methamphetamine (qualitative) (d-)Methamphetamine (quantitative) Buprenorphine (qualitative) Buprenorphine (quantitative) LSD (qualitative) LSD (quantitative) Methadone (qualitative) Methadone (quantitative)


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20




delta-9-THC-COOH (qualitative) delta-9-THC-COOH (quantitative) Benzodiazepine Lorazepam (qualitative) Benzodiazepine Lorazepam (quantitative) EDDP (qualitative) EDDP (quantitative) MDMA (qualitative) MDMA (quantitative)


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20


In Cooperation 77/156

IN COOPERATION

filter papers, each with 2 dried blood spots


17-Hydroxyprogesterone IRT PAP TSH



Samples and evaluation by Reference Institute for Bioanalytics, Bonn.


Feb. (1)

06.01.20 22.01.20 15.02.20

May (3)

03.03.20 07.04.20 02.05.20

July (4)

15.06.20 01.07.20 25.07.20

Oct. (6)

31.08.20 16.09.20 10.10.20

. 785 Newborn screening Hallbach / Spannagl NEW

2 samples of 10 ml urine (lyophilised)


Chromatographic analysis with identification of the active substance (STA)



From a list of 30 substances, the proof of 6 – 8 substances with chromatographic methods is required in both samples. Samples and evaluation by Reference Institute for Bioanalytics, Bonn.


May (3)

24.02.20 15.04.20 09.05.20

Sep. (5)

22.06.20 12.08.20 05.09.20

. 188 Systematic Toxicological Analysis (STA) Hallbach / Schneider

POCT78/156

POCT

2 samples of 2.5 ml, liquid controls


Chloride Glucose Urea Potassium Creatinine Lactate Magnesium Sodium pCO2 pO2 ionized Calcium pH


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 161 Blood Gas Analysis Luppa / Schneider


participation according to Rili-BÄK: quarterlyFraction CO-Hb Fraction Met-Hb Fraction O2-Hb Haemoglobin


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 162 Blood Gas Analysis – Haemoglobin Dorn-Beineke / Nebe



Chloride Urea Haemoglobin Potassium Lactate Sodium pCO2 pO2 ionized Calcium pH sO2


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 163 Blood Gas Analysis OPTI Systems Luppa / Schneider

POCT 79/156



AP Albumin Bilirubin Bilirubin conj. CK Calcium Chloride Cholesterol Protein GGT GOT GPT Glucose HDL-cholesterol Urea Uric Acid Potassium Creatinine LDH LDL-cholesterol Lactate Magnesium Sodium Phosphate Triglycerides VLDL-cholesterol alpha-Amylase tCO2


Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 810 Dry Chemistry 02 – POCT: Abaxis Piccolo System Falck / Nauck

2 samples of serum, plasma, lyophilised


AP Bilirubin CK Cholesterol GGT GOT GPT Glucose HDL-cholesterol Urea Uric Acid Potassium Creatinine Pancreas amylase Triglycerides alpha-Amylase


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 120 Dry Chemistry 03 – POCT: Reflotron Systems Falck / Nauck

2 samples of plasma or whole blood


Glucose

Point of Care Testing Systems


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 800 Dry Chemistry 01 – POCT: Glucose Petersmann / Nauck

Urine Analysis80/156

URINE ANALYSIS

2 samples urine, lyophilised / liquid

Albumin – Urine Ascorbic acid Bilirubin Protein Erythrocytes Glucose Ketone bodies Leucocytes Nitrite Urobilinogen hCG pH specific gravity


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 171 Urine Chemistry 01 (Qualitative) Fried / Niederau

2 samples urine, lyophilised / liquid


Albumin – Urine beta-2-Microglobulin Calcium Chloride Protein total Protein – Urine Glucose Urea Uric Acid IgG Potassium Creatinine Copper Magnesium Microalbumin Sodium Osmolality Pancreas amylase Phosphate Transferrine alpha-1-Microglobulin alpha-Amylase


Jan. (1)

08.11.19 15.01.20 29.01.20

Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 173 Urine Chemistry 02 (Quantitative) Fried / Falck


3-Methoxytyramine 5-Hydroxyindolea acid Epinephrine Dopamine Homovanillic acid Metanephrines Norepinephrine Normetanephrine Serotonin Vanillylmandelic acid


Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 175 Urine chemistry 03 (Biogene Amines) Schneider / Lutz

aurelijaz

Highlight

aurelijaz

Sticky Note

2.2 Šlapimo chemija 01 (Kokybinė)

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.21 Šlapimo chemija 02 (Kiekybinė)

Urine Analysis 81/156


Aminolaevulinic acid Heptaprorphyrin Hexaporphyrin Coproporphyrin 1 Coproporphyrin 3 Coproporphyrin total Pentaporphyrin Porphobilinogen Porphyrins total Uroporphorin


May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 178 Urine Chemistry 04 (Porphyrins) Kaiser / Kramer


Aldosterone Cortisol free hCG intact


May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 179 Urine Chemistry 05 (Hormones) Kaiser / Kramer



Sediment pictures

Also available online in digital microscopy!


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 172 Urine Chemistry 06 (Sediment Pictures) Fried / Niederau

Microbiology82/156

MICROBIOLOGY

1 set = 4 samples of 0.3 ml, lyophilised


PCR or other procedures for nucleic acid amplification/detection of specific DNA



May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 532 Bacterial Genome Detection – Bordetella pertussis Reischl / Ehrenschwender






May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 535 Bacterial Genome Detection – Borrelia burgdorferi Reischl / Fingerle





May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 544 Bacterial Genome Detection – Carbapenemase-Genes Reischl / Anders






May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 530 Bacterial Genome Detection – Chlamydia trachomatis & Neisseria gonorrhoeae Reischl / Baier

Microbiology 83/156






May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 540 Bacterial Genome Detection – Chlamydia pneumoniae Reischl / Maaß






May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 531 Bacterial Genome Detection – Chlamydia trachomatis Reischl / Baier






May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 545 Bacterial Genome Detection – Clostridium difficile (Toxin Gene) Reischl / Ehrenschwender






May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 542 Bacterial Genome Detection – Coxiella burnetii & Bacillus anthracis Reischl / Frangoulidis / Grass

Microbiology84/156






May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 534 Bacterial Genome Detection – EHEC / STEC Reischl / Ehrenschwender






May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 543 Bacterial Genome Detection – Francisella tularensis & Brucella spp. Reischl / von Buttlar / Scholz






May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 533 Bacterial Genome Detection – Helicobacter pylori Reischl / Ehrenschwender






May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 536 Bacterial Genome Detection – Legionella pneumophila Reischl / Ehrenschwender

Microbiology 85/156






May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 538 Bacterial Genome Detection – Listeria spp. Reischl / Ehrenschwender






May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 539 Bacterial Genome Detection – MRSA or cMRSA Reischl / Ehrenschwender






May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 541 Bacterial Genome Detection – Mycoplasma pneumoniae Reischl / Dumke






May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 537 Bacterial Genome Detection – Salmonella enterica Reischl / Ehrenschwender

Microbiology86/156





May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 547 Bacterial Genome Detection – Urogenital Panel Reischl / N.N.





May (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 546 Bacterial Genome Detection – VRE (Vancomycin Resistant Enterococci) Reischl / Ehrenschwender

Standardized stool samples – delivered with dry ice!additional sample not available

NGS-Analysis (next generation sequencing)

Variant shipment possible!


July (3)

13.03.20 13.05.20 23.07.20

. 580Bacterial Genome Detection – Molecular Genetic Analysis of the Human Microbiome

Gessner / Reischl


Polymerase chain reaction (PCR) and other procedures for detection of specific DNA



June (3)

13.03.20 13.05.20 05.06.20

Nov. (6)

21.08.20 21.10.20 11.11.20

. 560 Fungal Genome Detection – Pneumocystis jirovecii Reischl / Reiter-Owona

Microbiology 87/156

Please fill in page 04 of the order form for handling of infectious samples for EQAS unless you already returned your completed form 04 to INSTAND e. V. when you registered for recent EQA schemes. Without your confirmation we cannot send you the EQAS samples.

5 samples, lyophilised


Gram staining and cultivation, identification and susceptibility testing of bacteria

Participants in the EQA schemes in bacteriology will get a certificate for Gram staining when successful in this part.

Additional participation in EQA scheme No. 413 ´Gram Stain´ is not required.


A letter will only be sent in advance should the panel of antibioticas to be tested be changed:

Ampicillin Cefotaxim Ceftazidim Cefuroxim Ciprofloxacin Erythromycin Gentamicin Meropenem Oxacillin Penicillin Piperacillin/Tazobactam Tetracyclin Tobramycin Trimethoprim/Sulfamethoxazol Vancomycin Pivmecillinam Nitroxolin


Feb. (1)

13.12.19 12.02.20 21.02.20

Sep. (5)

17.07.20 09.09.20 18.09.20

. 412 Bacteriology (5 Samples) Schlüter / Ziesing

3 samples (drying process)


Gram staining and cultivation, identification and susceptibility testing of fast-growing bacteria and accompanying bacterial flora of the urogenital tract, incl. yeasts

Participants in the EQA schemes in bacteriology will get a certificate for Gram staining when successful in this part.

Additional participation in EQA scheme No. 413 ´Gram Stain´ is not required.


A letter will only be sent in advance should the panel of antibioticas to be tested be changed:

Ampicillin Ampicillin/Sulbactam Cefpodoximproxetil Ceftazidim Ciprofloxacin Fosfomycin-Trometamol Gentamicin Meropenem Nitrofurantoin Oxacillin Penicillin Trimethoprim/Sulfamethoxazol


Jan. (1)

08.11.19 22.01.20 31.01.20

Apr. (3)

07.02.20 01.04.20 15.04.20

July (4)

15.05.20 08.07.20 17.07.20

Nov. (6)

25.09.20 18.11.20 27.11.20

. 411 Bacteriology (3 Samples) Schlüter / Ziesing

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.6 Bakteriologija (5 mėginiai)

aurelijaz

Highlight

aurelijaz

Sticky Note

Dažymas Gramo būdu ir kultyvacija, identifikacija ir bakterijų jautrumo tyrimas

Microbiology88/156

3 slides (heat-fixed)


Evaluation of morphology and staining characteristics

Participants of the EQA schemes in bacteriology No. 411 or 412 will get a certificate for gram staining if they are successful in this part.

Additional participation in EQA scheme No. 413 ´Gram Stain´ is NOT required. EQA results can only be submitted online!


Mar. (2)

31.01.20 18.03.20 27.03.20

Oct. (6)

28.08.20 07.10.20 16.10.20

. 413 Bacteriology – Gram Stain Schlüter / Ziesing


Antibodies against Bordetella pertussis


Nov. (6)

07.08.20 21.10.20 04.11.20

. 317 Infection Serology – Bordetella pertussis Antibodies Hunfeld / N.N.



Antibodies against Borrelia


May (3)

13.03.20 13.05.20 28.05.20

Nov. (6)

07.08.20 21.10.20 04.11.20

. 332 Infection Serology – Borrelia burgdorferi Antibodies Hunfeld / N.N.


Antibodies against Campylobacter


May (3)

13.03.20 13.05.20 28.05.20

. 319 Infection Serology – Campylobacter Antibodies Hunfeld / N.N.

Microbiology 89/156


Antibodies against Chlamydia pneumoniae


May (3)

13.03.20 13.05.20 28.05.20

Nov. (6)

07.08.20 21.10.20 04.11.20

. 314 Infection Serology – Chlamydia pneumoniae (Chlamydophila) Antibodies Hunfeld / N.N.

2 slidesadditional sample not available


Direct detection of Chlamydia trachomatis antigen (dir. IFA)


May (3)

13.03.20 13.05.20 28.05.20

Nov. (6)

07.08.20 21.10.20 04.11.20

. 316 Infection Serology – Chlamydia trachomatis Direct Detection (Slide) Hunfeld / N.N.


Antibodies against Chlamydia trachomatis


May (3)

13.03.20 13.05.20 28.05.20

Nov. (6)

07.08.20 21.10.20 04.11.20

. 312 Infection Serology – Chlamydia trachomatis Antibodies Hunfeld / N.N.

2 samples of 0.3 ml, serumdditional sample not available

Antibodies against Coxiella burnetii


Nov. (6)

07.08.20 21.10.20 04.11.20

. 325 Infection Serology – Coxiella burnetii Antibodies Hunfeld / N.N.

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.4 Infekcinė serologija - Chlamydia pneumoniae (Chlamydophila) antikūnai

Microbiology90/156


Antibodies against Diphtheria toxoid


May (3)

13.03.20 13.05.20 28.05.20

Nov. (6)

07.08.20 21.10.20 04.11.20

. 318 Infection Serology – Diphtheria Toxoid Antibodies Hunfeld / N.N.


Antibodies against Helicobacter pylori


May (3)

13.03.20 13.05.20 28.05.20

Nov. (6)

07.08.20 21.10.20 04.11.20

. 334 Infection Serology – Helicobacter pylori Antibodies Hunfeld / N.N.


Antibodies against Mycoplasma pneumoniae


Nov. (6)

07.08.20 21.10.20 04.11.20

. 324 Infection Serology – Mycoplasma pneumoniae Antibodies Hunfeld / N.N.


Procalcitonin (qualitative) Procalcitonin (quantitative) Procalcitonin (semi-quantitative) Diagnostic comments


May (3)

13.03.20 13.05.20 28.05.20

Nov. (6)

07.08.20 21.10.20 04.11.20

. 320 Infection Serology – Procalcitonin Hunfeld / N.N.

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.3 Infekcinė serologija - Helicobacter pylori antikūnai

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.5 Infekcinė serologija - Mycoplasma pneumoniae antikūnai

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.20 Infekcinė serologija - Prokalcitoninas

Microbiology 91/156


participation according to Rili-BÄK: quarterlyRheumatoid factor (RF) (qualitative) Rheumatoid factor (RF) (semi-quantitative)


Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

13.03.20 13.05.20 28.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Nov. (6)

07.08.20 21.10.20 04.11.20

. 323 Infection Serology – Rheumatoid Factor Hunfeld / N.N.


Antibodies against Salmonella


May (3)

13.03.20 13.05.20 28.05.20

Nov. (6)

07.08.20 21.10.20 04.11.20

. 331 Infection Serology – Salmonella Antibodies Hunfeld / N.N.



anti-streptodornase (aDNase) (qualitative) anti-streptodornase (aDNase) (semi-quantitative) anti-streptolysin O (ASO) (qualitative) anti-streptolysin O (ASO) (semi-quantitative)


May (3)

13.03.20 13.05.20 28.05.20

Nov. (6)

07.08.20 21.10.20 04.11.20

. 321 Infection Serology – Streptococcal AB Hunfeld / N.N.


Antibodies against Tetanus toxoid


May (3)

13.03.20 13.05.20 28.05.20

Nov. (6)

07.08.20 21.10.20 04.11.20

. 310 Infection Serology – Tetanus Toxoid Antibodies Hunfeld / N.N.

Microbiology92/156




Antibodies against Treponema pallidum


May (3)

13.03.20 13.05.20 28.05.20

Nov. (6)

07.08.20 21.10.20 04.11.20

. 311 Infection Serology – Treponema pallidum Antibodies Hunfeld / N.N.


Antibodies against Yersinia


May (3)

13.03.20 13.05.20 28.05.20

. 315 Infection Serology – Yersinia Antibodies Hunfeld / N.N.



Direct detection of Chlamydia trachomatis antigen (ELISA, PCR)


May (3)

13.03.20 13.05.20 28.05.20

Nov. (6)

07.08.20 21.10.20 04.11.20

. 313 Infection Serology – Chlamydia trachomatis Direct Detection (ELISA / PCR) Hunfeld / N.N.

Microbiology 93/156


5 samples


Cultivation and species identification of fungi (yeasts, yeast-like fungi, hyphomycetes) occuring as the causative organism in case of mycosis of the mucosa, mycosis of the organs (deep-seated mycosis), systemic mycosis or mycosis aquired after trauma, as well as fungal contaminants present in human specimens. Furthermore, interpretation of the result should be performed (to some extent) within the framework of the provided information.


Feb. (1)

08.11.19 22.01.20 12.02.20

Oct. (5)

17.07.20 23.09.20 14.10.20

. 490Mycology 01 (Mucorales, Yeasts, Coelomycetes, Hyphomycetes, Basidiomycetes)

Haase / Geißdörfer / Schoerner

4 samples, living cultures


Differentiation of Dermatophytes, Yeasts and Moulds

Living strains of causative agents or contaminantes will be sent, that had been isolated from patients with skin mycoses or mucosal fungal infections.



May (2)

17.01.20 18.03.20 04.05.20

Oct. (5)

17.07.20 16.09.20 28.10.20

. 491 Mycology 02 (Dermatophytes, Yeasts, Mould Fungus) Gräser / Nenoff / Haase

Heparin whole blood, not stabilized, overnight shipping additional sample not available

Interferon Gamma Release Assay (IGRA)



Due to high demand two different sets of samples will be sent (Gr. 650 = Gr. 950).

Please note: This EQA scheme is for the users of TB-ELISPOT and the QuantiFERON-TB Gold test. Users of the QuantiFERON-TB Gold test prepare the samples according to the specification of the manufacturer for handling of Heparin tubes instead of QuantiFERON tubes.


May (3)

20.03.20 18.05.20 26.05.20

Oct. (6)

28.08.20 21.10.20 28.10.20

. 650 Interferon Gamma Release Assay (IGRA) Sack / Boldt

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.11 Mikologija 02 (Dermatofitai, Mielės, Pelėsinis grybelis)

aurelijaz

Highlight

aurelijaz

Sticky Note

Dermatofitų, mielių ir grybelių diferenciacija

Microbiology94/156

2 samples, serum


Candida antigen Candida total AB Candida IgA Candida IgG Candida IgM


Feb. (1)

08.11.19 22.01.20 05.02.20

Oct. (5)

24.07.20 23.09.20 07.10.20

. 480 Mycoserology 01 – Candida (Antigen+Antibodies) Weig / Bader

2 samples, serum or CSF

participation according to Rili-BÄK: half-yearlyDetection of Cryptococcus neoformans / Cryptococcus gattii Antigen


Feb. (1)

08.11.19 22.01.20 05.02.20

Oct. (5)

24.07.20 23.09.20 07.10.20

. 481 Mycoserology 02 – Cryptococcus neoformans/ – gattii Antigen Rickerts / Wilmes

1 set = 4 samples, lyophilised

Polymerase chain reaction (PCR) and other procedures for detection of specific DNA



Apr. (2)

17.01.20 18.03.20 08.04.20

Oct. (5)

17.07.20 16.09.20 07.10.20

. 492 Genome Detection of Dermatophytes Gräser / Nenoff

2 samples, thin blood smear and/or thick blood smear


In March and September: Prof. Hörauf, Bonn; in May and October: Prof. Tannich, Hamburg

Blood parasites – specification


Mar. (2)

10.01.20 04.03.20 18.03.20

May (3)

06.03.20 06.05.20 20.05.20

Sep. (5)

26.06.20 26.08.20 09.09.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 456 Parasite Microscopy ‘‘Blood‘‘ Tannich / Loderstädt / Hörauf / Reiter-Owona

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.14 Parazitų mikroskopija "Kraujas"

Microbiology 95/156

2 samples, fecal suspension or fecal smear

participation according to Rili-BÄK: half-yearlyStool parasites – specification


May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 451 Parasite Microscopy ‘‘Stool‘‘ Tannich / Loderstädt

2 samples variable volumes, serum or plasma

participation according to Rili-BÄK: yearlyAmoebiasis and echinococcosis


Oct. (6)

07.08.20 07.10.20 21.10.20

. 455 Parasite Serology – Amoebiasis and Echinococcosis Hörauf / Reiter-Owona



Malaria infection – clinical interpretation Malaria-Antibodies Schistosomen-Antibodies – IgG Schistosomiasis – clinical interpretation


May (3)

06.03.20 06.05.20 20.05.20

. 454 Parasite Serology – Malaria and Schistosomiasis Hörauf / Reiter-Owona



Toxoplasma-gondii-AB Toxoplasma-gondii-AB IgA Toxoplasma-gondii-AB IgG Toxoplasma-gondii-AB IgG – Avidity Toxoplasma-gondii-AB IgM Toxoplasmosis – clinical interpretation


May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 452 Parasite Serology – Toxoplasmosis Hörauf / Reiter-Owona

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.8 Parazitų serologija - Toksoplazmozė

Microbiology96/156

3 samples, stabilized EDTA-blood (and/or amniotic fluid), buffer


Toxoplasma gondii (DNA) – qualitative



Mar. (2)

10.01.20 04.03.20 18.03.20

Sep. (5)

26.06.20 26.08.20 09.09.20

. 457 Detection of Toxoplasma DNA (PCR) Hörauf / Reiter-Owona

6 samples, microscopic slides


Microscopic Detection of Mycobacteria



Mar. (2)

10.01.20 11.03.20 27.03.20

Sep. (5)

10.07.20 02.09.20 18.09.20

. 421 Mycobacteriology 01 – Microscopy Hillemann / Andres

5 samples, sputum specimensadditional sample not available


Nucleic Acid Amplification of Mycobacteria



Mar. (2)

10.01.20 11.03.20 27.03.20

Sep. (5)

10.07.20 02.09.20 18.09.20

. 424 Mycobacteriology 04 – NAT Hillemann / Andres

5 samples, sputum specimensadditional sample not available


Cultivation of Mycobacteria Differentiation of tuberculosis bacteria



May (2)

10.01.20 11.03.20 22.05.20

Nov. (5)

10.07.20 02.09.20 13.11.20

. 422 Mycobacteriology 02 – Culture Hillemann / Andres

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.7 Mikobakteriologija 01 - Mikroskopija

aurelijaz

Sticky Note

Mikroskopinis mikobakterijų nustatymas

Microbiology 97/156


5 samples, suspensions of mycobacterial strainsadditional sample not available


Identification of Mycobacteria



May (2)

10.01.20 11.03.20 04.05.20

Oct. (5)

10.07.20 02.09.20 23.10.20

. 423 Mycobacteriology 03 – Identification Hillemann / Andres

5 samples, suspensions of Mycobacterium tuberculosis complex strains for phenotypic resistance testing (incl. second-line drugs) additional sample not available


Susceptibility testing of mycobacteria



May (2)

10.01.20 11.03.20 04.05.20

Oct. (5)

10.07.20 02.09.20 23.10.20

. 425 Mycobacteriology 05 – Drug Susceptibility Testing Hillemann / Andres

5 samples, suspensions of Mycobacterium tuberculosis complex strains for molecular resistance testingadditional sample not available


Susceptibility testing of mycobacteria



May (2)

10.01.20 11.03.20 04.05.20

Oct. (5)

10.07.20 02.09.20 23.10.20

. 426 Mycobacteriology 06 – Molecular Drug Susceptibility Testing Hillemann / Andres

5 samples, for resistance testing of nontuberculous mycobacteriaadditional sample not available

Susceptibility Testing of nontuberculous mycobacteria



May (2)

10.01.20 11.03.20 04.05.20

Oct. (5)

10.07.20 02.09.20 23.10.20

. 427Mycobacteria diagnostics 01 – Drug Susceptibility Testing of nontuberculous mycobacteria

Hillemann / Andres NEW

Transfusion Medicine98/156

TRANSFUSION MEDICINE

2 sets of samples: 1 set = 1 x 5 ml serum / 1 x 5 ml erythrocytes suspension


A – Subtyping A B 0 – Typing Kell antigen Rh (D) Factor Rh – Subtyping (without Cw) Direct Antiglobulin Test Antibody Screening



Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 231 Immunohaematology 01 Wagner / Geisen

2 sets of samples: 1 set = 2 x 5 ml serum/1 x 5 ml erythrocytes suspension


A – Subtyping A B 0 – Typing Antibodyidentification Kell antigen Rh (D) Factor Rh – Subtyping (without Cw) Direct Antiglobulin Test Antibody Screening



Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 232 Immunohaematology 02 Wagner / Geisen

2 samples, anticoagulated whole blood (haematocrit 30%)


A – Subtyping A B 0 – Typing AntibodyidentificationKell antigen Rh (D) Factor Rh – Subtyping (without Cw) Direct Antiglobulin Test Antibody Screening



Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 237 Immunohaematology 05 (Machine-Based Analysis) Wagner / Geisen

Transfusion Medicine 99/156

4 DNA samplesadditional sample not available

Red cells: ABO, MNS, RHD, RHD-Deletion, RHCE, LU, KEL (K/k, Kp, Js), FY, JK, DI, YT, DO, CO, LW, KN, VEL.Platelets:HPA-1,2,3,4,5,6,9,15.Granulocytes:HNA-1a,-1b,-1c;HNA-3,HNA-4,HNA-5.

A list of the alleles necessary for successful participation can be found at:

www.instand-ev.de/mandatory-alleles



May (3)

06.03.20 06.05.20 20.05.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 235 Immunohaematology 06 – Molecular Diagnostic Bein / Flegel / Sachs

2 samples, anticoagulated whole blood (haematocrit 30%), 2 samples of plasma


A – Subtyping A B 0 – Typing AntibodyidentificationKell antigen Rh (D) Factor Rh – Subtyping (without Cw) Direct Antiglobulin Test Antibody Screening



Jan. (1)

08.11.19 15.01.20 29.01.20

May (3)

06.03.20 06.05.20 20.05.20

July (4)

30.04.20 01.07.20 15.07.20

Oct. (6)

07.08.20 07.10.20 21.10.20

. 238 Immunohaematology 07 (Machine-Based Analysis) Wagner / Geisen

3 samples of serum/plasma, 2 samples of DNA, 2 samples of platelet suspension

PlateletantibodiesPlateletantigens

This EQA scheme is intended for laboratories which are able to detect platelet alloantibodies and antigens.TheEQAschemeNo.235´Immunohaematology06–MolecularDiagnostic´wasdesignedforlaboratorieswhichonlywanttocarryoutplateletantigengenotyping.


Apr. (2)

10.01.20 04.03.20 01.04.20

Sep. (5)

03.07.20 26.08.20 23.09.20

. 233 Immunohaematology 03 – Platelet Immunology Kiefel / Bux / Kroll

Transfusion Medicine100/156

3 samples of plasma, 2 samples of DNAadditional sample not available

HNA/granulocyte antibodies HNA/granulocyte (neutrophil) antigens

ThisEQAschemeincludesallHNAspecifications.Itisdedicatedtolaboratorieswhichareabletodetectgranulocytealloantibodiesandantigens.

TheEQAschemeNo.235´Immunohaematology06–MolecularDiagnostic´wasdesignedfor laboratorieswhichonlywanttoperformHNAgenotyping.Becauseofthecomplicatedpreparationofthesamples,INSTANDe.V.reservestherighttonolongersupplylaboratorieswithproficiencytestsamples,whichhaverepeatedlynotsentbackanyresults.


Apr. (2)

10.01.20 04.03.20 01.04.20

Sep. (5)

03.07.20 26.08.20 23.09.20

. 234 Immunohaematology 04 – Granulocyte Immunology Bux / Kiefel / Kroll

Virus Diagnostics 101/156

VIRUS DIAGNOSTICS

INFORMATION ON VIRUS DIAGNOSTICS

The INSTAND EQA schemes in virology are carried out in scientific cooperation with the Deutsche Vereinigung zur Bekämpfung der Viruskrankheiten (DVV e.V.), Gesellschaft für Virologie (GfV e.V.) and Deutsche Gesellschaft für Hygiene und Mikrobiologie (DGHM e.V.). Cooperation partners are amongst others: Joint Diagnostic Commission of DVV and GfV, Robert Koch-Institut, Paul-Ehrlich-Institut, Friedrich-Loeffler-Institut, Bernhard-Nocht-Institut, Refe-rence Laboratories incl. National and International Reference Centers and National Consiliary Laboratories and Blood Transfusion Service of German Red Cross (DRK-Blutspendedienst Ost). The characterization of the EQA samples and the determination of the target values/consensus values are carried out in cooperation with the INSTAND Expert Laboratories.

Information for 2020:

(for details please see www.instand-ev.de -> EQAS and EQAS Online)

General remarks on the INSTAND EQA schemes in virus diagnostics

Please note that the samples of the respective EQA scheme are suitable for applying more than one method for the corresponding parameter.

Example: EQA scheme “Virus immunology – HIV-1 / HIV-2“ (335) – The 4 samples of the sample set of the EQA sche-me (335) can be analyzed on virus specific antibodies by different methods such as ELISA, ChLIA and other methods. The results of the respective method should be stated for all 4 samples of the sample set. The results reported for the different methods will be displayed in the participation document “listing and evaluation of the results”.

New EQA schemes 2020

In cooperation with the Joint Diagnostic Commission of DVV and GfV, INSTAND introduces seven new EQA schemes in the year 2020.

(433) Virus Genome Detection – Panel for Viral Meningitis / Encephalitis for Multiplex Tests 

and (404) Virus Genome Detection – Borna Viruses (405) Virus Genome Detection – Human Herpesvirus 6 (HHV-6) (406) Virus Genome Detection – Human Herpesvirus 8 (HHV-8) (407) Virus Genome Detection – Parechovirus (408) Virus Genome Detection – Torque Teno Virus (TTV) (415) Virus Immunology – Borna Viruses (Ab)

Planned EQA schemes

In cooperation with the Joint Diagnostic Commission of DVV and GfV, INSTAND plans to introduce the following new EQA schemes in 2020. Laboratories performing infectious disease diagnostics will be invited for an online survey.

Virus Genome Detection – Astrovirus Virus Genome Detection – Bocavirus Virus Genome Detection – Sapovirus

Schedule changes for EQA schemes

After participants’ feedback, the following INSTAND EQA schemes for virus resistance determination will be preponed to the September term starting in 2020:

(349) Virus Genome Detection – Cytomegalovirus Resistance Determination (397) Virus Genome Detection – Hepatitis B Virus Resistance Determination (399) Virus Genome Detection – Hepatitis C Virus -Resistance Determination (383) Virus Genome Detection – HIV-1 Drug Resistance Determination – Standard Program for Protease and Reverse Transcriptase Inhibitors (384) Virus Genome Detection – HIV-1 Drug Resistance Determination – additional Program 

for Integrase Inhibitors and Tropism Determination

Virus Diagnostics102/156


2 sets of samples; 1 set = 4 samples of 1.1 ml, lyophilised cell culture lysates


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for adenovirus DNA Determination of species of adenovirus Typing of adenovirus



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 371 Virus Genome Detection – Adenoviruses Zeichhardt / Kammel

2 sets of samples; 1 set = 4 samples of 1.1 ml, lyophilised plasma and suspensions of urine, respectively

Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for BK virus DNA


Cooperation with: Nationales Referenzzentrum für Papillom- und Polyomaviren, Institut für Virologie, Uniklinik Köln


Mar. (2)

24.01.20 11.03.20 27.03.20

Sep. (5)

17.07.20 02.09.20 18.09.20

. 364 Virus Genome Detection – BK Virus Zeichhardt / Kammel

2 sets of samples; 1 set = 4 samples of 1.1 ml, lyophilised cell culture lysates (inactivated)

Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for Borna viruses – RNA



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 404 Virus Genome Detection – Borna Viruses Zeichhardt / Kammel NEW



2 sets of samples; 1 set = 4 samples of 1.1 ml, lyophilised plasma and cell culture lysates, respectively (inactivated)

Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for CHIKV RNA


Cooperation with: WHO Collaborating Centre for Arbovirus and Haemorrhagic Fever Reference and Research Nationales Referenzzentrum für tropische Infektionserreger, Bernhard-Nocht-Institut für Tropenmedizin, Hamburg; Nationales Konsiliarlabor für FSME, Institut für Mikrobiologie der Bundeswehr, München


Mar. (2)

24.01.20 11.03.20 27.03.20

Sep. (5)

17.07.20 02.09.20 18.09.20

. 392 Virus Genome Detection – Chikungunya Virus Zeichhardt / Kammel


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for CoV RNA

Option of differentiation between MERS coronavirus and other human coronaviruses (samples which contain the MERS coronavirus are inactivated) other human coronaviruses (RNA) – quantitative other human coronaviruses (RNA) – qualitative MERS coronavirus (RNA) – quantitative MERS coronavirus (RNA) – qualitative


Cooperation with: Nationales Konsiliarlabor für Coronaviren, Institut für Virologie, Charité – Universitätsmedizin Berlin


June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 340 Virus Genome Detection – Coronaviruses Zeichhardt / Kammel

2 sets of samples; 1 set = 4 samples of 1.1 ml, lyophilised plasma and cell culture lysates, respectively


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for CMV DNA



Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 365 Virus Genome Detection – Cytomegalovirus Program 1 Zeichhardt / Kammel




Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for CMV DNA

The training samples will contain virus concentrations which fall outside the requirements of the specified RiliBÄK section B3.

The training program (368) can only be ordered together with the corresponding main EQA scheme (365) for March.

Separate certificates will be issued for the training program (368) and the main EQA scheme (365, subject to RiliBÄK-B3).


Cooperation with: Nationale Konsiliarlabore für Cytomegalievirus (CMV): Institut für Virologie, Universitätsklinikum Ulm; Institut für Medizinische Virologie und Epidemiologie der Viruskrankheiten, Universitätsklinikum Tübingen


Mar. (2)

24.01.20 11.03.20 27.03.20

. 368Virus Genome Detection – Cytomegalovirus Program 2 – additional Training Program (can only be ordered with program 365)

Zeichhardt / Kammel


Polymerase chain reaction (PCR), other nucleic acid amplification techniques (NAT) and sequencing for CMV resistance determination


Cooperation with: Nationale Konsiliarlabore für Cytomegalievirus (CMV): Institut für Virologie, Universitätsklinikum Ulm; Institut für Medizinische Virologie und Epidemiologie der Viruskrankheiten, Universitätsklinikum Tübingen


Sep. (5)

17.07.20 02.09.20 09.10.20

. 349 Virus Genome Detection – Cytomegalovirus Resistance Determination Zeichhardt / Kammel

Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for denguevirus RNA Typing of denguevirus


Cooperation with: WHO Collaborating Centre for Arbovirus and Haemorrhagic Fever Reference and Research Nationales Referenzzentrum für tropische Infektionserreger, Bernhard-Nocht-Institut für Tropenmedizin, Hamburg; Nationales Konsiliarlabor für FSME, Institut der Bundeswehr, München


Mar. (2)

24.01.20 11.03.20 27.03.20

Sep. (5)

17.07.20 02.09.20 18.09.20

. 369 Virus Genome Detection – Dengue Viruses Zeichhardt / Kammel



Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for enterovirus RNA Typing of enterovirus



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 372 Virus Genome Detection – Enteroviruses Zeichhardt / Kammel

1 set = 5 samples of 1.5 ml, suspension of feces additional sample not available

This ring test will only be carried out again in 2022!

Enterovirus types will be detected using polymerase chain reaction (PCR)/ nucleic acid amplification techniques (NAT), virus cultivation and subsequent typing in accordance with the Entero Surveillance Program run by the Robert Koch-Institut (RKI).

Please note: Specification of an enterovirus type is required in this EQA program. This program does NOT replace the EQA scheme “Virus genome detection – Enteroviruses (372)”!

Please note that participation in this special EQA program in accordance with the RKI-Entero Surveillance Program requires virus propagation in cell culture before carrying out virus typing.


Cooperation with: Nationales Referenzzentrum für Poliomyelitis und Enteroviren, Robert Koch-Institut, Berlin


Mar. (2)

24.01.20 11.03.20 17.04.20

. 374Special EQAS in Accordance with the RKI-Entero Surveillance Program Virus Detection – Enterovirus-PCR/Cultivation and Typing (typing required)

Zeichhardt / Kammel

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

5.2





Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for EBV DNA



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 376 Virus Genome Detection – Epstein Barr Virus Zeichhardt / Kammel

2 sets of samples; 1 set = 4 samples of 1.1 ml, lyophilised plasma


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for HAV RNA



Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 377 Virus Genome Detection – Hepatitis A Virus Zeichhardt / Kammel


Polymerase chain reaction (PCR), other nucleic acid amplification techniques (NAT) incl. sequencing for HBV genotyping


Cooperation with: Nationales Referenzzentrum für Hepatitis-B-Virus und Hepatitis-D-Virus, Institut für Medizinische Virologie, Justus-Liebig-Universität Gießen; WHO Collaborating Centre for Blood Products and IVD-Devices, Paul-Ehrlich-Institut, Langen


Nov. (6)

25.09.20 11.11.20 27.11.20

. 396 Virus Genome Detection – Hepatitis B Virus Genotyping Zeichhardt / Kammel





Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for HBV DNA



Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 361 Virus Genome Detection – Hepatitis B Virus Program 1 Zeichhardt / Kammel


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for HBV DNA





Cooperation with: Nationales Referenzzentrum für Hepatitis-B-Virus und Hepatitis-D-Virus, Institut für Medizinische Virologie, Justus-Liebig-Universität Gießen


Mar. (2)

24.01.20 11.03.20 27.03.20

. 378Virus Genome Detection – Hepatitis B Virus Program 2 – additional Training Program (can only be ordered with program 361)

Zeichhardt / Kammel

2 sets of samples; 1 set = 4 samples, plasmids in water and lyophilised plasma, respectively

Polymerase chain reaction (PCR), other nucleic acid amplification techniques (NAT) and sequencing for HBV resistance determination


Cooperation with: Nationales Referenzzentrum für Hepatitis-B-Virus und Hepatitis-D-Virus, Institut für Medizinische Virologie, Justus-Liebig-Universität Gießen


Sep. (5)

17.07.20 02.09.20 09.10.20

. 397 Virus Genome Detection – Hepatitis B Virus Resistance Determination Zeichhardt / Kammel



1 set = 5 samples of 1.1 ml, lyophilised sera and plasma, respectively


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for HCV geno- and subtype differentiation


Cooperation with: Nationales Referenzzentrum für Hepatitis C, Nationales Konsiliarlabor für Tollwut, Institut für Virologie, Universitätsklinikum Essen; Institut für Virologie, Universitätsklinikum Düsseldorf


Sep. (5)

17.07.20 02.09.20 18.09.20

. 375 Virus Genome Detection – Hepatitis C Virus Geno-/Subtyping Zeichhardt / Kammel



Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for HCV RNA



Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 362 Virus Genome Detection – Hepatitis C Virus Program 1 Zeichhardt / Kammel


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for HCV RNA







Mar. (2)

24.01.20 11.03.20 27.03.20

. 379Virus Genome Detection – Hepatitis C Virus Program 2 – additional Training Program (can only be ordered with program 362)

Zeichhardt / Kammel

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

5.3



1 set; 4 samples of 0.5 ml, lyophilised sera and plasma, respectively

Polymerase chain reaction (PCR), other nucleic acid amplification techniques (NAT) and sequencing for HCV resistance determination




Sep. (5)

17.07.20 02.09.20 09.10.20

. 399 Virus Genome Detection – Hepatitis C Virus -Resistance Determination Zeichhardt / Kammel


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for HDV RNA


Cooperation with: Nationales Referenzzentrum für Hepatitis-B-Virus und Hepatitis-D-Virus, Institut für Medizinische Virologie, Justus-Liebig-Universität Gießen; WHO Collaborating Centre for Blood Products and IVD-Devices, Paul-Ehrlich-Institut, Langen


Mar. (2)

24.01.20 11.03.20 27.03.20

Sep. (5)

17.07.20 02.09.20 18.09.20

. 400 Virus Genome Detection – Hepatitis D Virus Zeichhardt / Kammel

2 sets of samples; 1 set = 4 samples of 1.1 ml, lyophilised sera, plasma and suspension of feces, respectively


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for HEV RNA


Cooperation with: Nationales Konsiliarlabor für Hepatitis-A-Virus (HAV) und Hepatitis-E-Virus (HEV), Institut für Medizinische Mikrobiologie und Hygiene, Universität Regensburg


Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 380 Virus Genome Detection – Hepatitis E Virus Zeichhardt / Kammel





Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for differentiation of HSV 1 and HSV 2 DNA



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 363 Virus Genome Detection – Herpes Simplex Virus Type 1/Type 2 Zeichhardt / Kammel



Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for HIV-1 (RNA)



Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 360 Virus Genome Detection – HIV-1 (RNA) Program 1 Zeichhardt / Kammel







Cooperation with: Nationales Referenzzentrum für Retroviren, Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, München; Institut für Medizinische Virologie, Uniklinikum Frankfurt am Main


Mar. (2)

24.01.20 11.03.20 27.03.20

. 382Virus Genome Detection – HIV-1 (RNA) Program 2 – additional Training Program (can only be ordered with program 360)

Zeichhardt / Kammel

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

5.1


2 sets of samples; 1 set = 4 samples of 1.1 ml, buffer and plasma, respectively (non-lyophilised)

Please note: The samples will contain plasmids and heat-inactivated cell culture supernatant viruses respectively!

Polymerase chain reaction (PCR), other nucleic acid amplification techniques (NAT) and sequencing for HIV-1 drug resistance determination of protease inhibitors and reverse transcriptase inhibitors


Cooperation with: Nationales Referenzzentrum für Retroviren, Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, München; IMD Labor Frankfurt; Institut für Medizinische Virologie, Uniklinikum Frankfurt am Main; Institut für Klinische und Molekulare Virologie, Uniklinikum Erlangen; Nationales Referenzzentrum für Papillom- und Polyomaviren, Institut für Virologie, Uniklinik Köln; Medizinisches Infektiologiezentrum Berlin


Sep. (5)

17.07.20 02.09.20 09.10.20

. 383Virus Genome Detection – HIV-1 Drug Resistance Determination – Standard Program for Protease and Reverse Transcriptase Inhibitors

Zeichhardt / Kammel

2 sets of samples; 1 set = 2 samples of 1.1 ml, plasma (non-lyophilised)

Please note: The samples will contain heat-inactivated cell culture supernatant viruses!

Polymerase chain reaction (PCR), other nucleic acid amplification techniques (NAT) and sequencing for HIV-1 drug resistance determination of integrase inhibitors and determination of tropism


Cooperation with: Nationales Referenzzentrum für Retroviren, Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, München; IMD Labor Frankfurt; Institut für Medizinische Virologie, Uniklinikum Frankfurt am Main; Institut für Klinische und Molekulare Virologie, Uniklinikum Erlangen; Nationales Referenzzentrum für Papillom- und Polyomaviren, Institut für Virologie, Uniklinik Köln; Medizinisches Infektiologiezentrum Berlin


Sep. (5)

17.07.20 02.09.20 09.10.20

. 384Virus Genome Detection – HIV-1 Drug Resistance Determination – additional Program for Integrase Inhibitors and Tropism Determination

Zeichhardt / Kammel

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

5.4

aurelijaz

Highlight

aurelijaz

Sticky Note

5.5



2 sets of samples; 1 set = 4 samples of 1.1 ml, lyophilised plasma and sera, respectively



Cooperation with: Nationales Referenzzentrum für Retroviren, Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, München; Institut für Medizinische Virologie, Uniklinikum Frankfurt am Main


June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 395 Virus Genome Detection – HIV-2 (RNA) Zeichhardt / Kammel

2 sets of samples; 1 set = 5 samples of 1.1 ml, lyophilised cell culture lysates and biopsy materials, respectively


Polymerase chain reaction (PCR), other nucleic acid amplification techniques (NAT) and hybridization for HPV DNA Differentiation of ‚high risk‘ and ‚low risk‘ types, and typing of ‚high risk‘ HPV and ‚low risk‘ HPV




June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 373 Virus Genome Detection – Human Papilloma Viruses Zeichhardt / Kammel


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for HRV RNA Typing of human rhinovirus


Cooperation with: Institut für Virologie, Universitätsklinikum Düsseldorf; Institut für Virologie und Immunbiologie, Universität Würzburg; Nationales Konsiliarlabor für respiratorische Syncytialviren (RSV), Parainfluenzaviren, Metapneumoviren, Robert Koch-Institut, Berlin


June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 393 Virus Genome Detection – Human Rhinoviruses Zeichhardt / Kammel




Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for human metapneumovirus RNA




June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 385 Virus Genome Detection – Human Metapneumovirus Zeichhardt / Kammel


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for human herpesvirus 6 (HHV-6) DNA


Cooperation with: Institut für Klinische und Molekulare Virologie, Uniklinikum Erlangen; Institut für Virologie, Universitätsklinikum Bonn


Mar. (2)

24.01.20 11.03.20 27.03.20

Sep. (5)

17.07.20 02.09.20 18.09.20

. 405 Virus Genome Detection – Human Herpesvirus 6 (HHV-6) Zeichhardt / Kammel NEW


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for human herpesvirus 8 (HHV-8) DNA


Cooperation with: Institut für Virologie, Medizinische Hochschule Hannover


Mar. (2)

24.01.20 11.03.20 27.03.20

. 406 Virus Genome Detection – Human Herpesvirus 8 (HHV-8) Zeichhardt / Kammel NEW



1 set = 6 samples of 1.1 ml, lyophilised cell culture lysates and allantoic fluids, respectively


This program may be completed with currently circulating influenza viruses.

Please note: these EQA samples are not suitable for virus propagation and immune fluorescence tests for antigen detection. Some of the samples can contain chemically inactivated avian influenza A viruses.

Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for influenza A and B viruses and antigen testing Option for typing of seasonal and avian influenza A viruses


Cooperation with: Nationales Referenzzentrum für Influenza, Robert Koch-Institut, Berlin; Friedrich-Loeffler-Institut, Bundesforschungsinstitut für Tiergesundheit, Nationales Referenzlabor für Aviäre Influenza, Insel Riems


Mar. (2)

24.01.20 11.03.20 27.03.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 370Virus Detection (Genome/Antigen) – Influenza A and B Viruses incl. Avian Influenza A Viruses

Zeichhardt / Kammel

2 sets of samples; 1 set = 4 samples of 1.1 ml, lyophilised plasma and suspensions of urine, respectively

Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for JC virus DNA




Mar. (2)

24.01.20 11.03.20 27.03.20

Sep. (5)

17.07.20 02.09.20 18.09.20

. 394 Virus Genome Detection – JC Virus Zeichhardt / Kammel


2 sets of samples; 1 set = 4 samples, each on 1 sample disc (FTA card) with immobilized cell culture lysates


Please note: The cell culture lysates are immobilized on sample disks (FTA card). Potentially infectious viruses are chemically inactivated on the sample disk.

Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for mumps virus RNA Typing of mumps virus


Cooperation with: Nationales Referenzzentrum für Masern, Mumps, Röteln, Robert Koch-Institut, Berlin; Institut für Virologie, Universität Leipzig


June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 387 Virus Genome Detection – Mumps Virus Zeichhardt / Kammel

2 sets of samples; 1 set = 4 samples, each on 1 sample disc (FTA card) with immobilized

cell culture lysates

participation according to Rili-BÄK: half-yearlyPlease note: The cell culture lysates are immobilized on sample discs (FTA card).

Potentially infectious viruses are chemically inactivated on the sample disc.

Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for measles virus RNA Typing of measles virus




June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 386 Virus Genome Detection – Measles Virus Zeichhardt / Kammel



2 sets of samples; 1 set = 4 samples of 1.1 ml, lyophilised suspensions of feces


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for norovirus RNA with the option for differentiation in genogroup I and II


Cooperation with: Nationales Konsiliarlabor für Noroviren, Robert Koch-Institut, Berlin; Nationales Konsiliarlabor für Hepatitis-A-Virus (HAV) und Hepatitis-E-Virus (HEV), Institut für Medizinische Mikrobiologie und Hygiene, Universität Regensburg; Institut für Virologie, Medizinische Hochschule Hannover


Mar. (2)

24.01.20 11.03.20 27.03.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 381 Virus Genome Detection – Norovirus Zeichhardt / Kammel


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for parainfluenza virus RNA Typing of parainfluenza virus




Mar. (2)

24.01.20 11.03.20 27.03.20

Sep. (5)

17.07.20 02.09.20 18.09.20

. 388 Virus Genome Detection – Parainfluenza Viruses Zeichhardt / Kammel


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for parechovirus RNA


Cooperation with: Nationales Referenzzentrum für Poliomyelitis und Enteroviren, Robert Koch-Institut, Berlin


Mar. (2)

24.01.20 11.03.20 27.03.20

Sep. (5)

17.07.20 02.09.20 18.09.20

. 407 Virus Genome Detection – Parechovirus Zeichhardt / Kammel NEW





Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for parvovirus B19 DNA



Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 367 Virus Genome Detection – Parvovirus B19 Zeichhardt / Kammel



Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for RSV RNA and RSV antigen testing


Cooperation with: Institut für Virologie und Immunbiologie, Universität Würzburg; Institut für Virologie, Universitätsklinikum Düsseldorf Nationales Konsiliarlabor für respiratorische Syncytialviren (RSV), Parainfluenzaviren, Metapneumoviren, Robert Koch-Institut, Berlin


June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 359 Virus Genome Detection (Genome/Antigen) – Respiratory Syncytial Virus Zeichhardt / Kammel

2 sets of samples; 1 set = 4 samples of 1.1 ml, lyophilised suspension of feces

Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for rotavirus RNA Typing of rotavirus


Cooperation with: Nationales Konsiliarlabor für Rotaviren, Robert Koch-Institut, Berlin


June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 401 Virus Genome Detection – Rotaviruses Zeichhardt / Kammel



2 sets of samples; 1 set = 4 samples, each on 1 sample disc (FTA card) with immobilized cell culture lysates


Please note: The cell culture lysates are immobilized on sample discs (FTA card). Potentially infectious viruses are chemically inactivated on the sample disc.

Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for rubella virus RNA Typing of rubella virus




June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 389 Virus Genome Detection – Rubella Virus Zeichhardt / Kammel

2 sets of samples; 1 set = 4 samples of 1.1 ml, lyophilised samples (inactivated, vaccine)

Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for rabies virus RNA


Cooperation with: Nationales Konsiliarlaboratorium für Tollwut, Nationales Referenzzentrum für Hepatitis-C-Viren, Institut für Virologie, Universitätsklinikum Essen


Sep. (5)

17.07.20 02.09.20 18.09.20

. 390 Virus Genome Detection – Rabies Virus (Tollwutvirus) Zeichhardt / Kammel


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for Torque teno virus (TTV) DNA


Cooperation with: Institut für Virologie, Uniklinik Köln


Sep. (5)

17.07.20 02.09.20 18.09.20

. 408 Virus Genome Detection – Torque Teno Virus (TTV) Zeichhardt / Kammel NEW





Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for VZV DNA



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 366 Virus Genome Detection – Varicella Zoster Virus Zeichhardt / Kammel



Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for West Nile virus RNA Typing of West Nile virus (Lineage)


Cooperation with: WHO Collaborating Centre for Arbovirus and Haemorrhagic Fever Reference and Research Nationales Referenzzentrum für tropische Infektionserreger, Bernhard-Nocht-Institut für Tropenmedizin, Hamburg; Nationales Konsiliarlabor für FSME, Institut für Mikrobiologie der Bundeswehr, München


Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 391 Virus Genome Detection – West Nile Virus Zeichhardt / Kammel

2 sets of samples; 1 set = 4 samples of 1.1 ml, lyophilised cell culture lysates (inactivated)

Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for Zika virus RNA Typing of Zika virus (Lineage)


Cooperation with: WHO Collaborating Centre for Arbovirus and Haemorrhagic Fever Reference and Research Nationales Referenzzentrum für tropische Infektionserreger, Bernhard-Nocht-Institut für Tropenmedizin, Hamburg


Mar. (2)

24.01.20 11.03.20 27.03.20

Sep. (5)

17.07.20 02.09.20 18.09.20

. 403 Virus Genome Detection – Zika Virus Zeichhardt / Kammel



1 set = 3 samples of 1.1 ml, lyophilised suspensions of feces and cell culture lysates, respectively

Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for simultaneous qualitative detection of gastrointestinal adeno, astro, entero, noro, parecho, rota and sapoviruses, respectively.

This program will be completed with currently circulating virus variants.

The requirements of the RiliBÄK (Guidelines of the German Medical Association on quality assurance in medical laboratory testing / Bundesärztekammer) will be considered for the detection of the above-mentioned pathogens.

This EQA scheme will contain each of the above-mentioned pathogens at least once a year. It is recom-mended to participate at both EQA scheme terms.

Please note: Only results of multiplex tests will be accepted for EQA scheme 430

This multiplex EQA scheme is not suitable for (i) ´singleplex´ PCRs, (ii) tests for antigen detection, (iii) testing of sensitivity and (iv) typing. For this purpose, we refer to the INSTAND EQA schemes for the corresponding viruses.



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 430Virus Genome Detection – Gastrointestinal Virus Panel for Multiplex Tests

Zeichhardt / Kammel

1 set = 4 samples of 1.1 ml, lyophilised cell culture lysates

Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for simultaneous qualitative detection of respiratory adeno, boca, corona, entero, human metapneumo, human rhino, influenza A and B viruses incl. avian influenza A viruses, parecho, parainfluenza and respiratory syncytial viruses, respectively.


Some of the samples can contain chemically inactivated avian influenza A viruses.







June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 431Virus Genome Detection – Respiratory Virus Panel 1 for Multiplex Tests

Zeichhardt / Kammel




Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for simultaneous qualitative detection of adenoviruses , cytomegalovirus, enteroviruses , Epstein Barr virus, herpes simplex virus type 1, herpes simplex virus type 2, human herpesvirus 6, parechovirus and varicella zoster virus, respectively.








June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 433Virus Genome Detection – Panel for Viral Meningitis / Encephalitis for Multiplex Tests

Zeichhardt / Kammel NEW


Polymerase chain reaction (PCR) and other nucleic acid amplification techniques (NAT) for simultaneous qualitative detection of influenza A and B viruses incl. avian influenza A viruses and respiratory syncytial viruses (groups A and B).


Some of the samples can contain chemically inactivated avian influenza A viruses.






June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 432Virus Genome Detection – Respiratory Virus Panel 2 for Multiplex Tests

Zeichhardt / Kammel NEW



4 samples of 0.3 ml, serum (inactivated in case of chikungunya virus RNA positive samples)

Anti-CHIKV IgG Anti-CHIKV IgG – avidity Anti-CHIKV IgM




Sep. (5)

17.07.20 02.09.20 18.09.20

. 402 Virus Immunology – Chikungunya Virus (Ab) Zeichhardt / Kammel


Anti-CMV IgG Anti-CMV IgG – avidity Anti-CMV IgM



Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 351 Virus Immunology – Cytomegalovirus (Ab) Zeichhardt / Kammel

10 samples of 100 µl, serum and plasma, respectively

Anti-Borna virus IgG



June (4)

17.04.20 03.06.20 19.06.20

. 415 Virus Immunology – Borna Viruses (Ab) Zeichhardt / Kammel NEW

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.9 Virusų Immunologija - Citomegalovirusas (Ab)



4 samples of 0.3 ml, serum (inactivated in case of dengue virus RNA positive samples)

Anti-dengue virus IgG Anti-dengue virus IgM dengue virus-NS1 Ag clinical interpretation




Mar. (2)

24.01.20 11.03.20 27.03.20

Sep. (5)

17.07.20 02.09.20 18.09.20

. 350 Virus Immunology – Dengue Viruses (Ab and NS1 Antigen) Zeichhardt / Kammel


Antibodies against EBV with and without differentiation of antigen specificity (incl. avidity) and heterophilic antibodies clinical interpretation



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 352 Virus Immunology – Epstein Barr Virus (Ab) Zeichhardt / Kammel


Anti-TBE/FSME virus IgG Anti-TBE/FSME virus IgG – avidity Anti-TBE/FSME virus IgM



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 358 Virus Immunology – Tick-Borne Encephalitis (TBE/FSME) Virus (Ab) Zeichhardt / Kammel

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.10 Virusų imunologija - Erkinio Encefalito (TBE/FSME) Virusas (Ab)



4 samples of 0.5 ml, serum (inactivated in case of Hantavirus RNA positive samples)

Antibodies against hantaviruses (IgG and IgM) and differentiation of serotype specific antibodies Status of hantavirus infection


Cooperation with: Nationales Konsiliarlabor für Hantaviren, Charité – Universitätsmedizin Berlin, Campus Mitte, Institut für Virologie, Berlin


Mar. (2)

24.01.20 11.03.20 27.03.20

Sep. (5)

17.07.20 02.09.20 18.09.20

. 355 Virus Immunology – Hantaviruses (Ab) Zeichhardt / Kammel



Anti-HAV IgG / Anti-HAV total Anti-HAV IgM



Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 343 Virus Immunology – Hepatitis A Virus (Ab) Zeichhardt / Kammel

12 samples of serum


HBsAg (1 ml) Confirmation test HBsAg Anti-HBs (0.75 ml) Anti-HBc (0.75 ml)



Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 344 Virus Immunology – Hepatitis B Virus Program 1 (HBsAg, Anti-HBs, Anti-HBc) Zeichhardt / Kammel





Anti-HBc IgM HBeAg Anti-HBe



Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 345Virus Immunology – Hepatitis B Virus Program 2 (Anti-HBc-IgM, HBeAg, Anti-HBe)

Zeichhardt / Kammel

4 samples of 0.5 ml, serum and plasma, respectively


Screening test anti-HCV and combined detection anti-HCV and HCV antigen HCV antigen Complementary test (blot) anti-HCV



Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 346 Virus Immunology – Hepatitis C Virus (Ab and HCV Antigen) Zeichhardt / Kammel


Anti-HDV IgG / Anti-HDV total Anti-HDV IgM



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 347 Virus Immunology – Hepatitis D Virus (Ab) Zeichhardt / Kammel


Anti-HEV IgG Anti-HEV IgM



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 348 Virus Immunology – Hepatitis E Virus (Ab) Zeichhardt / Kammel




Anti-HSV 1/2 IgG Anti-HSV 1/2 IgG – avidity Anti-HSV 1 IgG Anti-HSV 1 IgG – avidity Anti-HSV 2 IgG Anti-HSV 2 IgG – avidity Anti-HSV 1/2 IgM Anti-HSV 1 IgM Anti-HSV 2 IgM



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 354 Virus Immunology – Herpes Simplex Viruses (Ab) Zeichhardt / Kammel



Screening test anti-HIV-1 / anti-HIV-2 (3rd and 4th Generation) Confirmation test (blot and other confirmatory test) anti-HIV-1 / anti-HIV-2 Confirmation test (blot and other confirmatory test) anti-HIV-1 Confirmation test (blot and other confirmatory test) anti-HIV-2



Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 335 Virus Immunology – HIV-1/HIV-2 (Ab) Zeichhardt / Kammel



HIV-1 p24 Ag HIV-1 p24 Ag Confirmation test



Mar. (2)

24.01.20 11.03.20 27.03.20

June (4)

17.04.20 03.06.20 19.06.20

Sep. (5)

17.07.20 02.09.20 18.09.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 337 Virus Immunology – HIV-1 p24 Antigen Zeichhardt / Kammel




Screening test anti-HTLV-1 / anti-HTLV-2 Confirmation test (Blot and other confirmation test) anti-HTLV-1 / anti-HTLV-2


Cooperation with: Nationales Referenzzentrum für Retroviren, Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, München; Institut für Klinische und Molekulare Virologie, Uniklinikum Erlangen


June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 339 Virus Immunology – HTLV-1/HTLV-2 (Ab) Zeichhardt / Kammel



Anti-measles virus IgG Anti-measles virus IgG – avidity Anti-measles virus IgM



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 357 Virus Immunology – Measles Virus (Ab) Zeichhardt / Kammel



Anti-mumps virus IgG Anti-mumps virus IgG – avidity Anti-mumps virus IgM



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 356 Virus Immunology – Mumps Virus (Ab) Zeichhardt / Kammel

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.12 Virusų imunologija - Tymų virusas (Ab)




Anti-parvovirus B19 IgG Anti-parvovirus B19 IgG – avidity Anti-parvovirus B19 IgM



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 342 Virus Immunology – Parvovirus B19 (Ab) Zeichhardt / Kammel



Anti-rubella virus IgG Anti-rubella virus IgG – avidity Anti-rubella virus IgM



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 341 Virus Immunology – Rubella Virus (Ab) Zeichhardt / Kammel

2 samples of 0.5 ml, serum and plasma, respectively (vaccinee)

Anti-rabies Virus


Cooperation with: Nationales Referenzzentrum für Hepatitis C, Nationales Konsiliarlabor für Tollwut, Institut für Virologie, Universitätsklinikum Essen


Sep. (5)

17.07.20 02.09.20 18.09.20

. 336 Virus Immunology – Rabies Virus (Tollwutvirus) (Ab) Zeichhardt / Kammel

aurelijaz

Highlight

aurelijaz

Highlight

aurelijaz

Sticky Note

2.13 Virusų imunologija - Raudoniukės virusas (Ab)





Anti-VZV IgG Anti-VZV IgG – avidity Anti-VZV IgM



June (4)

17.04.20 03.06.20 19.06.20

Nov. (6)

25.09.20 11.11.20 27.11.20

. 353 Virus Immunology – Varicella Zoster Virus (Ab) Zeichhardt / Kammel

3 samples of 0.3 ml, serum (inactivated in case of Zika virus RNA positive samples)

Anti-ZIKV IgG Anti-ZIKV IgG – avidity Anti-ZIKV IgM




Sep. (5)

17.07.20 02.09.20 18.09.20

. 338 Virus Immunology – Zika Virus (Ab) Zeichhardt / Kammel

Addresses of the EQA Scheme Experts and Assistants

133/156

Nationales Referenzzentrum für gramnegative Krankenhauserreger Abteilung für Medizinische Mikrobiologie Ruhr-Universität Bochum Universitätsstraße 150 44801 Bochum

T +49 234 3227 888 E [email protected]

Dr. med. Agnes Anders

Forschungszentrum Borstel Nationales Referenzzentrum für Mykobakterien Parkallee 18 23845 Borstel

T +49 4537 188 6480 F +49 4537 188 3110 E [email protected]

Dr. Sönke Andres

Institut für Medizinische Mikrobiologie Universität Göttingen Kreuzbergring 57 37075 Göttingen


Dr. rer. nat. Oliver Bader

Institut für Medizinische Mikrobiologie Universitätsklinikum Jena Erlanger Allee 101 7747 Jena


Dr. med. Michael Baier

Institut für Laboratoriumsmedizin, Mikrobiologie und Blutdepot Regionale Kliniken Holding RKH GmbH Posilipostraße 4 71640 Ludwigsburg

T +49 7141 99 65800/01 F +49 7141 99 65819 E [email protected]

Prof. Dr. med. Hannsjörg Baum

HELIOS Klinikum Berlin-Buch Klinik für Hämatologie und Stammzelltransplantation Schwanebecker Chaussee 50 13125 Berlin


Dr. med. Herrad Baurmann

Justus-Liebig-Universität Gießen Institut für Klinische Immunologie und Transfusionsmedizin Langhansstraße 7 35392 Gießen


Prof. Dr. med. Gregor Bein

MVZ Labor PD Dr. Volkmann & Kollegen Kriegsstraße 99 76133 Karlsruhe


Dr. rer. nat. Martin Blüthner


134/156

Universitätsklinikum Leipzig AöR Institut für Klinische Immunologie Johannisallee 30 4103 Leipzig

T +49-341 97 25830 F +49 341 972 5828 E [email protected]

Dr. rer. nat. Andreas Boldt

Linnenkamp 19 58093 Hagen

T +49 170 2714867 F +49 3212 1160527 E [email protected]

Prof. Dr. med. Jürgen Bux

Gerinungszentrum Rhein-Ruhr Konigstraße 13 47051 Duisburg

T +49 203 348 336 24 E [email protected]

Dr. rer. nat. Morten O. Christensen

Klinikum der Universität München Abteilung für Transfusionsmedizin, Zelltherapeutika und Hämostaseologie Marchioninistr. 15d 81377 München


Dr. rer. biol. hum. Andrea Dick

Würmtal-Labor Robert-Koch-Allee 7 82131 Gauting


Dr. med. Heinz Diem

HELIOS Dr. Horst Schmidt Kliniken Wiesbaden Institut für Labordiagnostik und Hygiene Ludwig-Erhard-Straße 100 65199 Wiesbaden

T +49 171 7840475 E [email protected]

Dr. med. Alexandra Dorn-Beineke

Medizinische Fakultät der TU Dresden Institut für Medizinische Mikrobiologie und Hygiene Fetscherstraße 74 1307 Dresden


Dr. Roger Dumke

Labor Becker & Kollegen MVZ GbR Führichstr. 70 81671 München

T +49 89 450 917 349 F +49 89 450 917 6349 E [email protected]

Prof. Dr. rer. nat. Dr. med. Jürgen Durner


135/156

Institut für Klinische Mikrobiologie und Hygiene Universitätsklinik Regensburg (UKR) Franz-Josef-Strauß-Allee 11 93053 Regensburg


PD Dr. med. Dr. rer. nat. Martin Ehrenschwender

University Department of Laboratory Medicine University Milano Bicocca Piazza dell‘Ateneo Nuovo, 1 20126 Milano Italien

T +39 362-385312 F +39 362-383296 E [email protected]

Dr.ssa Rosanna Falbo

Instand e.V. Ubierstr. 20 40223 Düsseldorf


Dr. rer. nat. Manfred Falck

Nationales Referenzzentrum für Borrelien Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit und Lebensmittelsicherheit (LGL) Veterinärstraße 2 85764 Oberschleißheim

T +49 9131 6808 5870 F +49 9131 6808 5197 E volker.fi [email protected]

Dr. med. Volker Fingerle

Chief, Laboratory Services Section DTM/CC/NIH Bethesda MD 20892-1184 USA

T +1 301 5947 401 F +1 301 4969 990 E bill.fl [email protected]

Prof. Dr. med. Willy A. Flegel

Am Lindenbruch 48 45327 Essen

T +49 160 2131 052 E r.fl [email protected]

Dr. rer. nat. Ralf-Rüdiger Flörke

Institut für Mikrobiologie der Bundeswehr Neuherbergstraße 11 80937 München


PD Dr. med. Dimitrios Frangoulidis

MQ Zürich, Universitätsspital Zürich Institut für Klinische Chemie Rämistrasse 100 8091 Zürich Schweiz


Dr. Roman Fried


136/156

MVZ Alexianer Labor GmbH Krausnickstraße 17 10115 Berlin


Dr. med. Claudia Frömmel

St. Marienkrankenhaus Medizinische Klinik III Kampenstr. 51 57072 Siegen


Prof. Dr. med. Winfried Gassmann

Mikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene Universitätsklinikum Erlangen Wasserturmstraße 3-5 91054 Erlangen


Dr. rer. nat. Walter Geißdörfer

DRK-Blutspendedienst Baden-Württemberg-Hessen Sandhofstraße 1 60528 Frankfurt am Main


Dr. med. Christof Geisen

Institut für Medizinische Mikrobiologie und Hygiene Universitätsklinikum Regensburg Franz-Josef-Strauß-Allee 11 93053 Regensburg


Prof. Dr. Dr. med. André Gessner

Klinikum Augsburg Institut für Transfusionsmedizin und Hämostaseologie Stenglinstraße 2 86156 Augsburg


Andreas Giebl

Charité - Universitätsmedizin Berlin Institut für Mikrobiologie und Hygiene, Nationales Konsiliarlabor für Dermatophyten Hindenburgdamm 27, 1. OG, Raum 148 12203 Berlin


Prof. Dr. rer. nat. Yvonne Gräser


T +49 992692 2806 F +49 89 992692 3983 E [email protected]

PD Dr. rer. nat. Gregor Grass


137/156

MVZ aescuLabor Hamburg GmbH - amedes Haferweg 36 22769 Hamburg


Prof. Dr. med. Kai Gutensohn

Labordiagnostisches Zentrum - Bereich Mikrobiologie Universitätsklinikum RWTH Aachen Pauwelsstraße 30 52074 Aachen

T +49 241 8089 515/510 F +49 241 8033 89515/80824 E [email protected]

Prof. Dr. med. Gerhard Haase

Klinische Pharmakologie am Lehrstuhl für Psychiatrie und Psychotherapie und am Lehrstuhl für Pharmakologie und Toxikologie der Universität Universitätsstraße 84 93053 Regensburg


Prof. Dr. med. Dr. rer. nat. Ekkehard Haen

MLL Münchner Leukämielabor GmbH Max-Lebsche-Platz 31 81377 München


Prof. Dr. med. Dr. phil. Torsten Haferlach

Forschungszentrum Borstel Nationales Referenzzentrum für Mykobakterien Parkallee 18 23845 Borstel


Dr. rer. nat. Doris Hillemann

Institut für Klinische Transfusionsmedizin und Immungenetik Ulm (IKT) Helmholtzstraße 10 89081 Ulm


Dr. med. Britta Höchsmann

Institut für Laboratoriumsmedizin Deutsches Herzzentrum München Lazarettstraße 36 80636 München


Prof. Dr. med. Stefan Holdenrieder

Institut für Medizinische Mikrobiologie, Immunologie und Parasitologie Universitätsklinikum Bonn Sigmund-Freud-Straße 25 53127 Bonn


Prof. Dr. med. Achim Hörauf


138/156

Klinikum der Universität München, Campus Großhadern Abteilung für Transfusionsmedizin, Zelltherapeutika und Hämostaseologie Marchioninistr. 15 81377 München


Prof. Dr. med. Andreas Humpe

Zentralinstitut für Labormedizin, Mikrobiologie & Krankenhaushygiene Krankenhaus Nordwest Steinbacher Hohl 2-26 60488 Frankfurt am Main


Prof. Dr. med. Klaus-Peter Hunfeld

INSTAND e.V. Ubierstraße 20 40223 Düsseldorf


Dr. Patricia Kaiser

Institut für Qualitätssicherung in der Virusdiagnostik - IQVD Potsdamer Chaussee 80 14129 Berlin


Dr. rer. nat. Martin Kammel

Gerinnungszentrum Rhein-Ruhr Königstraße 13 47051 Duisburg


Dr. med. Günther Kappert



Prof. Dr. med. Wolfgang Kern

Institut für Transfusionsmedizin Universitätsmedizin Rostock Ernst-Heydemann-Straße 6 18057 Rostock


Prof. Dr. med. Volker Kiefel

Im Gabelacker 18 69120 Heidelberg

T +49 6221 40 0098 E kirschfi [email protected]

Prof. Dr. med. vet. Michael Kirschfi nk


139/156

Universitätsklinikum Köln Innere Medizin 1 Kerpener Straße 62 50937 Köln


Dr. Dipl.-Biol. Fanni Kleinert

Bremer Zentrum für Labormedizin GmbH Friedrich-Karl-Straße 22 28205 Bremen


Prof. Dr. med. Mariam Klouche

INSTAND e. V. Ubierstraße 20 40223 Düsseldorf


Dipl.-Ing. (FH) Udo Kramer

Universitätsklinikum Köln Innere Medizin I Kerpener Straße 62 50937 Köln


Prof. Dr. med. Karl-Anton Kreuzer

Institut für Transfusionsmedizin Dessau DRK-Blutspendedienst NSTOB Altener Damm 50 6847 Dessau


Dr. med. Hartmut Kroll

Charité-Universitätsmedizin Berlin, ZTB-Zentrum für Transfusionsmedizin und Zelltherapie Berlin gGmbH, Gewebetypisierung am Campus Virchow-Klinikum Augustenburger Platz 1 13353 Berlin


Dr.-Ing. Nils Lachmann

Bernhard-Nocht-Institut für Tropenmedizin Nationales Referenzzentrum für Tropische Infektionserreger Bernhard-Nocht-Str. 74 20359 Hamburg

T +49 (0)40-42818-0

Ulrike Loderstädt

Institut für Klinische Chemie und Pathobiochemie Klinikum rechts der Isar Ismaninger Straße 22 81675 München


Prof. Dr. med. Peter B. Luppa


140/156

Medizinische Laboratorien Düsseldorf Nordstraße 44 40477 Düsseldorf


Dr. med. Thomas Lutz

Labor Dr. Heidrich und Kollegen MVZ GmbH Stuvkamp 22 22081 Hamburg


Prof. Dr. med. Matthias Maaß

Am Bärenkamp 22 40589 Düsseldorf


Prof. Dr. med. Friedrich Maly

Kantonsspital Aarau AG Institut für Labormedizin Tellstrasse 25 5001 Aarau Schweiz


Dr. Adriana Méndez

Institut für Klinische Chemie und Laboratoriumsmedizin Universitätsmedizin Greifswald Körperschaft des öffentlichen Rechts Ferdinand-Sauerbruch-Straße 17475 Greifswald


Prof. Dr. med. Matthias Nauck

Hämatologie-Labor Mannheim Hans-Böckler-Straße 1 68161 Mannheim


Dr. med. Thomas Nebe

Labor für medizinische Mikrobiologie Mölbiser Hauptstraße 8 4571 Rötha/OT Mölbis


Prof. Dr. med. Pietro Nenoff

Carl-Thiem-Klinikum Cottbus gGmbH Zentrum für Laboratoriumsmedizin, Mikrobiologie und Krankenhaushygiene Thiemstraße 111 3048 Cottbus


Dr. rer. nat. Stefan Neubeck


141/156

MVZ Labor Dortmund Leopoldstraße GbR Leopoldstraße 10 44147 Dortmund


Dr. med. Christoph Niederau

HELIOS Klinikum Berlin-Buch Institut für Labormedizin Schwanebecker Chaussee 50, Haus 222 13125 Berlin


Prof. Dr. med. Dirk Peetz

Institut für Klinische Chemie und Laboratoriumsmedizin Universitätsmedizin Greifswald Körperschaft des öffentlichen Rechts Ferdinand-Sauerbruchstraße 17475 Greifswald


Dr. med. Dipl.-Biol. Astrid Petersmann

Semmelweis University IIIrd Department of Medicine, Research Laboratory Kutvölgyi st. 4. 1125 Budapest Ungarn

T +361 3251379 F +361 2129351 E [email protected]

Prof. Zoltan Prohaszka

Mühlenstr. 3c 37073 Göttingen

T +49 176 26349445 E [email protected]

Prof. Dr. rer. nat. Hansotto Reiber

Klinik Bad Trissl GmbH Abteilung für Innere Medizin I und Palliativmedizin Bad-Trissl-Straße 73 83080 Bad Trissl

T +49 80 33 20-285 F +49 080 33 20-310 E [email protected]

Dr. med. Roland Reibke

Institut für Medizinische Mikrobiologie und Hygiene Universitätsklinikum Regensburg Franz-Josef-Strauß-Allee 11 93053 Regensburg


Prof. Dr. rer. nat. Udo Reischl

Institut für Medizinische Mikrobiologie, Immunologie und Parasitologie Universitätsklinikum Bonn Sigmund-Freud-Straße 25 53127 Bonn


Dr. med. vet. Ingrid Reiter-Owona


142/156

Carl-Thiem-Klinikum Cottbus gGmbH Zentrum für Laboratoriumsmedizin, Mikrobiologie und Krankenhaushygiene Thiemstraße 111 3048 Cottbus

T +49 355 46-2480 F +49 355 46-2030 E [email protected]

PD Dr. med. Karl H. Reuner

Robert Koch-Institut FG 16 Erreger von Pilz- und Parasiteninfektionen und Mykobakteriosen Seestraße 10 13353 Berlin


PD Dr. med. Volker Rickerts

Klinische Pharmakologie am Lehrstuhl für Pharmakologie und Toxikologie der Universität Universitätsstr. 31 93053 Regensburg

T +49 941 943 4766 F +49 941 943 5832 E fl [email protected]

Florian Ridders

Synlab MVZ Weiden GmbH MVZ Gera, Betriebstätte Oncoscreen Jena Löbstädter Straße 93 7749 Jena


Dr. med Martin Roskos

Justus-Liebig-Universität Gießen Institut für Klinische Immunologie und Transfusionsmedizin Langhansstraße 7 35392 Gießen


Prof. Dr. med. Ulrich Sachs

Institut für Klinische Immunologie Universitätsklinikum Leipzig AöR Johannisallee 30 4103 Leipzig


Prof. Dr. med. Ulrich Sack



Dr. med. Richard Schabath

Haus Gravener Straße 42a 40764 Langenfeld


Prof. Dr. rer. nat. Peter Schadewaldt


143/156

Hochschule Anhalt Institute of Bioanalytical Sciences (IBAS) Strenzfelder Allee 28 6406 Bernburg


Prof. Dr. rer. nat. Ingo Schellenberg

Medizinische Hochschule Hannover und Krankenhaushygiene Institut für Medizinische Mikrobiologie Carl-Neuberg-Straße 1 30625 Hannover


Prof. Dr. med. Dirk Schlüter

Institut für Klinische Chemie und Pathobiochemie Klinikum rechts der Isar Ismaninger Straße 22 81675 München


Dr. rer. nat. Heike Schneider

Mikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene Universitätsklinikum Erlangen Wasserturmstraße 3-5 91054 Erlangen

T +499131 85-22583 F +499131 85-22117 E [email protected]

Dr. med. Dipl.-Chem. Christoph Schoerner

Institut für Mikrobiologie der Bundeswehr Leiter Konsiliarlabor für Yersinia pestis Abteilung Bakteriologie und Toxinologie Neuherbergstrasse 11 80939 München


Prof. Dr. rer. nat. Holger C. Scholz

Beiertheimer Allee 44 76137 Karlsruhe


Prof. Dr. med. Hans-Peter Seelig

Ludwig-Maximilians-Universität Klinik für Anästhesiologie Ziemssenstraße 1 80336 München


Prof. Dr. med. Michael Spannagl

Institut für Klinische Chemie und Pathobiochemie Klinikum rechts der Isar Ismaningerstraße 22 81675 München


Prof. Dr. med. Werner Steimer


144/156

Universitätskinderklinik Abteilung Kinderheilkunde I Hoppe-Seyler-Straße 1 72076 Tübingen


Prof. Dr. med. Martin Stern

Bernhard-Nocht-Institut für Tropenmedizin Nationales Referenzzentrum für Tropische Infektionserreger Bernhard-Nocht-Straße 74 20359 Hamburg


Prof. Dr. med. Egbert Tannich

Max-Planck-Institut für Psychiatrie Kraepelinstraße 2-10 80804 München

T +49 89-30622-651 /-269 F +49 89 30622 310 E [email protected]

PD Dr. med. Dr. rer. nat. Manfred Uhr

Zentrallaboratorien der Klinikum Bremen-Nord, Bremen-Ost und Links der Weser Klinikum Links der Weser Senator-Weßling-Straße 1 28277 Bremen

T +49 421 879 4557 F +49 421 4971998101 E [email protected]

Prof. Dr. med. Nicolas von Ahsen


T +49 992692 3894 F +49 89 992692 3983 E [email protected]

Dr. med. vet. Heiner von Buttlar

DRK-Blutspendedienst NSTOB Eldagsener Straße 38 31832 Springe


PD Dr. med. Franz F. Wagner

Institut für Medizinische Mikrobiologie Universitätsmedizin Göttingen Kreuzbergring 57 37075 Göttingen


Prof. Dr. med. Michael S. Weig

Fakultät Medical and Life Sciences Campus Villingen-Schwenningen Jakob-Kienzle-Str. 17 78054 Villingen-Schwenningen


Prof. Dr. med. Folker Wenzel


145/156

Robert Koch-Institut FG 16 Erreger von Pilz- und Parasiteninfektionen und Mykobakteriosen Seestraße 10 13353 Berlin


Dr. med. Dunja Wilmes

Instand e.V. Ubierstr. 20 40223 Düsseldorf T +49 211 1592 1341 E [email protected]

Dr. Nathalie Wojtalewicz

Charité-Universitätsmedizin Berlin, ZTB-Zentrum für Transfusionsmedizin und Zelltherapie Berlin gGmbH, Gewebetypisierung am Campus Virchow-Klinikum Augustenburger Platz 1 13353 Berlin


Sükran Zaralioglu

Institut für Qualitätssicherung in der Virusdiagnostik - IQVD Potsdamer Chaussee 80 14129 Berlin


Prof. Dr. rer. nat. Heinz Zeichhardt

Nationales Referenzzentrum für TSE Klinik für Neurologie Universitätsmedizin Göttingen Robert-Koch-Straße 40 37075 Göttingen


Prof. Dr. med. Inga Zerr

Medizinische Hochschule Hannover Institut für Medizinische Mikrobiologie Carl-Neuberg-Straße 1 30625 Hannover


Dr. med. Stefan Ziesing

labopart – Medizinische Laboratorien DC Bauer, Dr. Gerber, Prof. Dr. Bühling Wurzener Straße 5 1127 Dresden


Dr. rer. nat. Thomas Zimmermann

Hochschulklinik für Dermatologie, Venerologie und Allergologie Immunologisches Zentrum Städtisches Klinikum Dessau Medizinische Hochschule Brandenburg Auenweg 38 6847 Dessau


Prof. Dr. med. Christos C. Zouboulis

146/156

Index

Symbols(d-)Methamphetamine (176) 76

11-39 ACTH (298) 621-84 PTH (301) 621,25-OH Cholecalciferol (290) 5810-OH-Carbamazepine (192, 860) 69, 7317-beta-Estradiol (302) 6317-Hydroxyprogesterone (309, 785) 64, 76

221-Hydroxylase (773) 3025-OH CCF (Vitamin D) (290) 58

33-Methoxytyramine (175) 80

44-Hydroxyproline (710) 51

55-Hydroxyindolea acid (175) 80

99-OH-Risperidone (862) 74

AA - Subtyping (231, 232, 237, 238) 98, 99A B 0 - Typing (231, 232, 235, 237, 238) 98, 99a1-Antitrypsine (241) 56a1-AT S-Locus (743) 27a1-AT Z-Locus (743) 27a1-Globulins (102, 141) 52, 55a1-Glycoprotein (241) 56A1298C (732, 747) 24, 26A149P (793) 26A174D (793) 26a2-Globulins (102, 141) 52, 55a2-Makroglobulin (241) 56AB quantitation (238) 99ACE (630) 50Acid phosphatase (100) 55Acid-fast bacilli (421) 96ACT (286) 45ADAMTS13-I (510) 47ADAMTS13-II (511) 48Adenoviruses (371, 430, 431, 433) 102, 120, 121ADHS-Treatment (879) 74aDNase (321) 91Adrenal Gland (298) 62AFP (292, 306) 57, 64Alanine (710) 51Albumin

(100, 102, 141,  171, 460, 810) 52, 55, 66, 79, 80

Aldolase (100) 55Aldolase B (793) 26Aldosterone (179, 304) 62, 81Allergy Diagnostic (653, 720) 16, 19allo-Isoleucine (710) 51alpha-1-Microglobulin (173) 80alpha-Aminoadipic acid (710) 51

alpha-Amylase (100, 120, 173, 810) 55, 79, 80alpha-Globin (794) 35alpha1-Antitrypsin (743) 27Alprazolam (876) 72Aluminium (205, 206) 61Amicacin (197) 73Amino Acid Analysis (710) 51Aminolaevulinic acid (178) 81Amiodarone (190) 68Amisulpride (861, 873) 71, 73Amitriptyline (199, 203, 204, 863) 74, 75Ammonia (118) 51Amoebiasis (455) 95Amphetamine (174) 76Ampicillin (890) 69Amyloid ß Peptid 40 (Aß40) (466) 67Amyloid ß Peptid 42 (Aß42) (466) 67ANA (251) 16ANCR (786) 33Androstendion (309) 64Angiotensin-Converting-Enzyme (630) 50Anti -P450 C17 -Hydroxylase (263) 18Anti - Acetylcholin Receptors (269) 18Anti - Actin (253) 16Anti - Adrenal Cortex (263) 18Anti - Amphiphysin 1 (265) 18Anti - Asialoganglioside (AGA1) (267) 18Anti - Borna virus (415) 122Anti - BPAg-1 (259) 17Anti - BPAg-2 (259) 17Anti - C1 inhibitor (250) 58Anti - Cardiolipin (275) 19Anti - CCP (cyclic citrulline peptide) (273) 19Anti - CHIKV (402) 122Anti - CMV (351) 122Anti - deamidated Gliadin (271) 19Anti - dengue virus (350) 123Anti - Desmoglein-1 (259) 17Anti - Desmoglein-3 (259) 17Anti - Desmoplakin (259) 17Anti - Desmosomes (259) 17Anti - DFS70/LEDGF (251) 16Anti - Disialoganglioside (GD1a) (267) 18Anti - Disialoganglioside (GD1b) (267) 18Anti - ds-DNA (251) 16Anti - Endomysium (271) 19Anti - Glia Cell Nuclear Antibody

(AGNA) (265) 18Anti - Gliadin (271) 19Anti - glomerular basement membrane

(GBM) (257) 17Anti - Glutamic Acid Decarboxylase

(GAD) (261) 17Anti - H+/K+-ATPase (253) 16Anti - HAV (343) 124Anti - HBc (344) 124Anti - HBc-IgM (345) 125Anti - HBe (345) 125Anti - HBs (344) 124Anti - HCV (346) 125Anti - HDV (347) 125Anti - Hemidesmosomes (259) 17Anti - HEV (348) 125Anti - HIV-1 (335) 126Anti - HIV-2 (335) 126Anti - HSV (354) 126Anti - HTLV-1 (339) 127Anti - HTLV-2 (339) 127Anti - HuD (265) 18Anti - Insulin (IAA) (261) 17Anti - Islet Cells (ICA) (261) 17Anti - Jo 1 (Histidyl-tRNA-Synthetase) (255) 17

Anti - MCV (mutated citrullinated Vimentin) (273) 19

Anti - measles virus (357) 127Anti - Microsomes (LKM 1) (253) 16Anti - Mikrosomen (295) 63Anti - Mitochondria (253) 16Anti - Monosialoganglioside (GM1) (267) 18Anti - Monosialoganglioside (GM2) (267) 18Anti - Monosialoganglioside (GM3) (267) 18Anti - MPO (257) 17Anti - Mullerian hormone (297) 62Anti - mumps virus (358) 127Anti - Musclespecific Receptor

Tyrosinkinase (MuSK) (269) 18Anti - Myelin-associated Glycoprotein

(MAG) (267) 18Anti - Neuronal Nuclei (265) 18Anti - P450 C21 -Hydroxylase (263) 18Anti - P450 ssc -Hydroxylase (263) 18Anti - Parietal Cells (253) 16Anti - parvovirus B19 (342) 128Anti - PM / Scl (255) 17Anti - PR3 (257) 17Anti - Purkinje Cells (265) 18Anti - Quadrosialoganglioside (GQ1b) (267) 18Anti - rabies Virus (336) 128Anti - Ri / Nova 1 (265) 18Anti - rubella virus (341) 128Anti - Skeletal Muscle (269) 18Anti - Sm (255) 17Anti - Sm (D) (255) 17Anti - Smooth Muscle (253) 16Anti - SOX1 (265) 18Anti - ß2-Glycoprotein (IgG) (275) 19Anti - ß2-Glycoprotein (IgM) (275) 19Anti - SSA / Ro (255) 17Anti - SSA / Ro (52kD - Proteins) (255) 17Anti - SSA / Ro (60kD - Proteins) (255) 17Anti - SSB / La (255) 17Anti - streptodornase (321) 91Anti - streptolysin O (321) 91Anti - Ta (Ma 2) (265) 18Anti - TBE/FSME (358) 123Anti - Titin (269) 18Anti - Topoisomerase-1 (Scl 70) (255) 17Anti - TPO (295) 63Anti - Transglutaminase IgA (271) 19Anti - Trisialoganglioside (GT1b) (267) 18Anti - Tyreoglobulin (295) 63Anti - Tyrosine Phosphatase (IA2) (261) 17Anti - U1 -snRNP (Anti - U1 -70K) (255) 17Anti - VZV (353) 129Anti - Yo (CDR62) (265) 18Anti - ZIKV (338) 129Anti - Zinc Transporter 8 (ZnT8A) (261) 17Antiarrhytmics (190) 68Antibacterials (193, 890) 68, 69Antibodies against Bordetella pertussis (317) 88Antibodies against Borrelia (332) 88Antibodies against campylobacter (319) 88Antibodies against Chlamydia

pneumoniae (314) 89Antibodies against Chlamydia

trachomatis (312) 89Antibodies against Coxiella burnetii (325) 89Antibodies against diphtheria toxoid (318) 90Antibodies against EBV (352) 123Antibodies against hantaviruses (355) 124Antibodies against Helicobacter pylori (334) 90Antibodies against mycoplasma

pneumoniae (324) 90Antibodies against salmonella (331) 91

147/156

Index

Antibodies against tetanus toxoid (310) 91Antibodies against Treponema

pallidum (311) 92Antibodies against Yersinia (315) 92Antibody ID (232, 237, 238) 98, 99Antibody Screening (231, 232, 237, 238) 98, 99Anticonvulsants (191, 192, 871, 872) 69, 70Antifungals (198, 602) 70Antimon (207, 208) 61Antiphospholipid Syndrome (275) 19Antipsychotic Drugs (200, 873–875) 70, 71Antipsychotic Drugs (200, 873–875) 70, 71Antithrombin (225, 285, 792) 28, 41, 43Antivirals (850) 71AP (100, 120, 810) 55, 79APC resistance (288) 43Apixaban (504) 44ApoB (771) 29Apolipoprotein A1 (151) 55Apolipoprotein B (151) 55Apolipoprotein E (151, 734, 744) 23, 27, 55aPTT (221, 230, 280, 285, 286) 40–43, 45Argatroban (230) 41Arginine (710) 51Argininosuccinic acid (710) 51Aripiprazole (860) 73Arsenic (205, 206, 208) 61Ascorbic acid (171) 80Ascorbic acid (Vitamin C) (296) 58Asialotransferrin (750) 50ASO (321) 91Asparagine (710) 51Aspartic acid (710) 51Astroviruses (430) 120AT (225) 41AT3 (792) 28Atazanavir (850) 71Atomoxetine (879) 74ATP 7 B: H 1069 Q (745) 27Auto-anti C1q (245) 59Auto-anti FH (249) 58Autoimmune Dermatitis (259) 17Autoimmune Diseases

(251, 253, 255, 257, 259, 261, 263,  265, 267, 269, 271, 273, 275) 16–19

Autoimmune Endocrinopathies (263) 18Avian Influenza (370) 114Avidity

(338, 341, 342, 351, 353,  354, 356–358, 402) 122, 123, 126–129

AZF (788) 34

Bb-Alanine (710) 51B-cells (617, 651) 20, 38B-Lymphocytes (213) 38Bacillus anthracis (542) 83Bacterial Genome Detection

(530–547, 580) 82–86Bacteriology (411–413) 87, 88Barbiturate-phenobarbiturate (174) 76Basidiomycetes (490) 93Basophil Activation Test (653) 19Basophilic Granulocytes (612) 37Bb (247) 59Becker-Duchenne (780) 32Benzodiazepine Lorazepam (177) 76Benzodiazepines (876–878) 72Benzoylecgonine (174) 76Beryllium (207) 61beta-2-Microglobulin (173, 292) 57, 80

Beta-Globin (794) 35beta-Globulins (102, 141) 52, 55Bilirubin (100, 110, 120, 171, 810) 55, 56, 79, 80

52, 80586110249

36, 377894

36, 375212036

82, 88102, 12282, 88

673232728476

17

Biogene Amines (175, 185) Biotin (Vitamin H) (290) Bismuth (207) BK Virus (364) Bleeding Disorder (512) Blood Cell Count (209, 211) Blood Gas Analysis (161–163) Blood parasites (456) Blood Smear Analysis

(212, 612) BNP (761) Bocaviruses (431) Bone Marrow Cytology (218) Bordetella pertussis (317, 532) Borna Viruses (404, 415) Borrelia burgdorferi (332, 535) Borrelia IgG Antibody Index

(AI) calculation (465) BRCA1 (779) BRCA2 (779) Bromazepam (878) Brucella spp. (543) Buprenorphine (176)

Cc-ANCA (257)C-Peptide (300) 63C-Reactive Protein (241, 322, 810) 51, 56, 79C1 inhibitor (246) 59C1-Inhibitor (225) 41C1q proteine (246) 59C282Y (733, 741) 24, 27C3 - nephritic factor (248) 59C3-Complement (241, 246) 56, 59C3-nephritic factor (248) 59C3a (247) 59C3d (247) 59C4-Complement (241, 246) 56, 59CA 125 (292) 57CA 15-3 (292) 57CA 19-9 (292) 57CA 72-4 (292) 57Cadmium (205, 206, 208) 61Caffeine (870) 68Calcitonin (299, 301) 57, 62Calcium (100, 173, 810) 55, 79, 80Calcium Metabolism (301) 62Calprotectin (130) 53CALR (768) 34Campylobacter (319) 88Candida antigen (480) 94Capillary Zone Electrophoresis (102) 55Carbamacepine (195) 73Carbamazepine-epoxide (192) 69Carbapenemase-Genes (544) 82Cardiac markers (760) 52Case Study (512, 513) 49CD16+ (651) 20CD19+ (651) 20CD3+ (651) 20CD34 (217) 38CD34+ events (217) 38CD4 (213) 38CD4+ (651) 20CD45+ (617) 38CD45+ events (217) 38CD56+ (651) 20CD8 (213) 38

CEA (292) 57Cefepime (890) 69Ceftazidime (890) 69Cellular Immunodeficiency Diagnostic (651) 20Cerebrospinal Fluid Analysis

(460, 462–466) 66, 67Cerebrospinal Fluid Cytology (470) 131Cerebrospinal Fluid Cytology (470) 131CFTR Common Mutations (778) 31CHE (100) 55Chikungunya Virus (392, 402) 103, 122Chimerism Diagnostics (618) 21Chlamydia pneumoniae (314, 540) 83, 89Chlamydia trachomatis

(312, 313, 316, 530, 531) 82, 83, 89, 92Chloramphenicol (198) 70Chlordiazepoxide (876) 72Chloride (100, 161, 163, 173, 810) 55, 78–80Chlorprotixene (875) 71Cholesterol (100, 120, 151, 810) 55, 79Chromatographic analysis (188) 77Chromium (205, 206, 208) 61Citalopram (860) 73Citrulline (710) 51CK (100, 120, 810) 55, 79CK-MB (760) 52Clobazam (878) 72Clobazepam (878) 72Clomipramine (199, 203, 204, 863) 74, 75Clonazepam (877) 72Clostridium difficile (545) 83Clozapine (200, 862, 863) 70, 74cMRSA (539) 85Cobalamin (Vitamin B12) (290) 58Cobalt (205, 206, 208) 61Coelomycetes (490) 93Coeruloplasmin (241) 56Collagen Receptor C807T (739) 25Collagen receptor GP Ia/IIa (C 807 T) (739) 25

5958, 59

59

Complement activation products (247) Complement Analysis (245–250) Complement factor H (246) Complement factor I (246) 59Concentration of Hb in reticulocytes (216) 37Connective Tissue Diseases (251, 255) 16, 17Connexin 26 (782) 32Copper (100, 173, 205, 206) 55, 61, 80Copper-Binding Protein (745) 27Coproporphyrin (178) 81Coronaviruses (340) 103Coronaviruses (431) 120Cortisol free (179, 302) 63, 81Coxiella burnetii (325, 542) 83, 89Creatinine (100, 120, 161, 173, 810) 55, 78–80Cryptococcus gattii (481) 94Cryptococcus neoformans (481) 94Cyclosporine A (601) 72CYFRA 21-1 (292) 57Cyp21A2 (773) 30CYP2C19 (775) 30CYP2C9 (775) 30CYP2D6 (777) 31Cystathionine (710) 51Cystatin-C (242) 56Cysteine-Homocysteine-disulfide (710) 51Cystine (710) 51Cytomegalovirus

(349, 351, 365, 368, 433) 103, 104, 121, 122

148/156

Index

DD-Dimer (226, 285) 41, 43Dabigatran (502) 43Darunavir (850) 71delta-9-THC-COOH (177) 76Dementia Markers (466) 67Dengue Viruses (350, 369) 105, 123Dermatophytes (491) 93Dermatophytes Genome Detection (492) 94Desalkylflurazepam (876) 72Desethylamiodarone (190) 68Desipramine (202–204, 863) 74, 75Desmethyl fluoxetine (874) 71Desmethyl olanzapine (875) 71Desmethyl sertraline (873) 71Detection of mycobacteria by culture (422) 96DHEA (298) 62DHEA-S (298) 62Diabetes mellitus (261) 17Diazepam (876) 72Digitoxin (197) 73Digoxin (195) 73Diphtheria Toxoid (318) 90Direct Antiglobulin Test

(231, 232, 237, 238) 98, 99Direct detection of Chlamydia

trachomatis antigen (313, 316) 89, 92Disialotransferrin (750) 50Dolutegravir (850) 71Dopamine (175, 185) 52, 80Doxepin (201, 203, 204, 863) 74, 75DPD (777) 31Drug Resistance Determination

(349, 383, 384, 397, 399) 104, 107, 109, 111Drugs of Abuse (174, 176, 177) 76Duloxetine (862) 74Dystrophin (780) 32

EEchinococcosis (455) 95EDDP (177) 76Edoxaban (505) 44Efavirenz (850) 71EHEC (534) 84Elvitegravir (850) 71ENA (255) 17Endocrinopathies (263) 18Engraftment Diagnostics (618) 21Enteroviruses

(372, 374, 430, 431, 433) 105, 120, 121Eosinophilic Granulocytes (612) 37Epinephrine (175, 185) 52, 80Epstein Barr Virus (352, 376, 433) 106, 121, 123Erythrocytes (171, 211, 612) 36, 37, 80Erythropoiesis (218) 36Erythropoietin (626) 64Escitalopram (861) 73Eslicarbazepine (871) 69Ethanol (700) 53Ethosuximid (195) 73Ethylglucuronid (751) 50Etravirine (850) 71Everolimus (601) 72

FFactor II (223) 40Factor IX (224) 40Factor IX Inhibitor (514) 48Factor V (223) 40

Factor V-Leiden (730, 740) 23, 25Factor VII (223) 40Factor VIII (227) 41Factor VIII Inhibitor (220) 46Factor X (223) 40Factor XI (224) 40Factor XII (224) 40Factor XIII (224) 40FDP screening (222) 40Fecal Diagnostics (130, 131) 53Fecal elastase (130) 53Felbamate (871) 69Ferritin (241) 56Fertility (297) 62Fibrinogen (222, 285) 40, 43Fibrinogen Receptor (749) 25Flavine Adenine Dinucleotide (FAD) (291) 58Flavine mononucleotid (FMN) (291) 58Fluconazole (198) 70Flucytosine (198) 70Flunitrazepam (877) 72Fluoride (205, 206) 61Fluoxetine (874) 71Flurazepam (877) 72Fluvoxamine (873) 71FMR1 (781) 32Folic acid (290) 58Fondaparinux (501) 43Food allergen (720) 16Fraction CO-Hb (162) 78Fraction Met-Hb (162) 78Fraction O2-Hb (162) 78Fragile X (781) 32Francisella tularensis (543) 84Free beta-chain hCG (305) 64Free Haemoglobin (236) 37Free light chains (243) 54Fructosamine (146) 53FSH (297) 62Fungal Genome Detection (560) 86

GGabapentin (872) 70gamma-Globulins (100, 102, 141) 52, 55Gammopathies (243) 54Gastrin (300) 63Gastrointestinal Virus Panel (430) 120Gentamicin (197) 73GGT (100, 120, 810) 55, 79GJB2 (782) 32GLDH (100) 55Glomerulopathies (257) 17Glucagon (300) 63Glucose

(100, 111, 120, 161, 171,  173, 464, 800, 810) 54, 55, 67, 78–80

Glutamic acid (710) 51Glutamine (710) 51Gluten-Sensitive Enteropathies (271) 19Glycine (710) 51Gold (206) 61GOT (100, 120, 810) 55, 79GPI deficient cells (616) 39GPT (100, 120, 810) 55, 79Gram Stain (411–413) 87, 88Granulocyte (neutrophil) antigens (234) 100Granulocyte antibodies (234) 100Granulocyte Immunology (234) 100Granulopoiesis (218) 36

HH63D (741) 27Haematocrit (209, 211, 612) 36, 37Haematology

(209–218, 236, 612,  616, 617) 36–39Haemoglobin

(131, 162, 163, 209, 211, 612) 36, 37, 53, 78 Haemoglobin-Haptoglobin-Complex (131) 53 Haemoglobinopathies (210) 39 Haemostasis

(220–228, 230, 280–283, 285–289,  501–505, 509–514) 40–49

Haloperidol (862) 74Hantaviruses (355) 124Haptoglobin (131, 241) 53, 56HbA1c (145) 58HBDH (100) 55HBeAg (345) 125HBsAg (344) 124hCG intact (171, 179, 292, 306) 57, 64, 80, 81HCV Antigen (346) 125HDL-cholesterol (120, 151, 810) 55, 79HE4 (292) 57Helicobacter pylori (334, 533) 84, 90Hematopoetic Growth Factors (626) 64Hemopexin (241) 56Hepatic Syndromes (253) 16Hepatitis A Virus (343, 377) 106, 124Hepatitis B Virus

(344, 345, 361,  378, 396, 397) 106, 107, 124, 125

Hepatitis C Virus (346, 362, 375, 379, 399) 108, 109, 125

Hepatitis D Virus (347, 400) 109, 125Hepatitis E Virus (348, 380) 109, 125Heptaprorphyrin (178) 81HER2/new (292) 57Herpes Simplex Viruses

(354, 363, 433, 463) 66, 110, 121, 126Hexaporphyrin (178) 81HFE (741) 27HFE: C 282 Y (733) 24HFE: H 63 D (733) 24HFE: S 65 C (733) 24HGH (298) 62HHV-6 (405) 113HHV-8 (406) 113Histidine (710) 51HIT-I (287) 46HIV (850) 71HIV-1 (335, 360, 382–384) 110, 111, 126HIV-1 p24 Antigen (337) 126HIV-2 (335, 395) 112, 126HLA Antibody Screening and

Specification (445) 22HLA Crossmatching (443) 23HLA Typing (441, 442, 444) 21, 22HLA-B27 Determination (440) 21HLA-DQ (772) 29HNA (234, 235) 99, 100HNPCC (783) 33Holotranscobalamine (290) 58Homocystein (151) 55Homovanillic acid (175) 80Hormones

(294–298, 300–302, 304–306, 309) 58, 62–64HPA (235, 749) 25, 99hsCRP (240) 57HTLV-1 (339) 127HTLV-2 (339) 127HTT Huntingtin (784) 33

149/156

Index

Human Herpesvirus (405) 113Human Herpesvirus (406) 113Human Metapneumovirus (385) 113Human Papilloma Viruses (373) 112Human Rhinoviruses (393) 112Hydroxy-Itraconazole (602) 70Hyphomycetes (490) 93

IIdentification of mycobacteria (423) 97Identification of tubercle-bacilii (422) 96IgA (100, 241, 243, 460) 54–56, 66IgE (241, 720) 16, 56IgG (100, 173, 241, 243, 460) 54–56, 66, 80IgG Subclasses (244) 54IgM (100, 241, 243, 460) 54–56, 66IGRA (650) 93IL28B (777) 31Imipramine (202–204, 863) 74, 75Immature reticulocytes (216) 37Immunogenetics (440–445) 21–23Immunohaematology

(231–235, 237, 238) 98–100Immunophenotyping (213, 214, 617) 38, 39Immunosuppressants (601, 602) 70, 72Infection Serology

(310–325, 331, 332, 334) 51, 88–92Infektion Serology (332) 88Influenza Viruses (370, 431, 432) 114, 120, 121Inhaled allergen (720) 16INR (221, 285, 286) 40, 43, 45Insect poison allergen (720) 16Insulin (300) 63Integrase Inhibitors (384) 111Interferon Gamma Release Assay (650) 93Iodine (205, 206) 61ionized Calcium (161, 163) 78Iron (100, 205, 206) 55, 61Iron binding capacity (100) 55IRT (785) 76Isoleucine (710) 51Itraconazole (602) 70

JJC Virus (394) 114

KK-ras Codon 12 mutation (776) 31K-ras Codon 13 mutation (776) 31K-ras Codon 61 mutation (776) 31Kell antigen (231, 232, 237, 238) 98, 99Ketone bodies (171) 80KIT (767) 34

LLacosamide (871) 69Lactase-gene (770) 29Lactate (100, 161, 163, 464, 810) 55, 67, 78, 79Lamotrigine (191, 860) 69, 73LCT (770) 29LDH (100, 810) 55, 79LDL-cholesterol (151, 810) 55, 79Lead (205, 208) 61Lectin pathway (246) 59Legionella pneumophila (536) 84Leucine (710) 51

Leucocytes (171, 209, 211, 213, 217, 612, 617) 36–38, 80

Levetiracetam (191) 69Levomepromazine (873) 71LH (297) 62Linezolid (890) 69Lipase (100) 55Lipids (151) 55Lipoproteins (151) 55Listeria spp. (538) 85Lithium (100, 195) 55, 73LMW Heparin (281) 42Lopinavir (850) 71Lorazepam (878) 72Lp (a) (151) 55LSD (176) 76Lupus Anticoagulant (228) 45Lymphocytes (213, 612) 37, 38Lysine (710) 51

MMagnesium

(100, 161, 173, 208, 810) 55, 61, 78–80Malaria (454) 95Manganese (205, 206, 208) 61Maproptiline (202, 863) 74Maraviroc (850) 71Markers of Ethanol Abuse (750, 751) 50MCV (211, 612) 36, 37MDMA (177) 76Measles Virus (357, 386, 463) 66, 115, 127Megakaryopoiesis (218) 36MEN2A (738) 28Mercury (205, 208) 61Meropenem (890) 69MERS (340) 103Metanephrines (175) 80Methadone (176) 76Methionine (710) 51Methotrexate (197) 73Methylmalonic Acid (187) 58Methylphenidate (879) 74Mianserine (874) 71Microalbumin (173) 80Microbiome (580) 86Mirtazapine (861) 73MLH1 (783) 33MNS (235) 99Molybdaen (207) 61Monocytes (612) 37Morphology (413) 88Morphology of erythrocytes (212) 36Morphology of leukocytes (212) 36Morphology of platelets (212) 36Mould Fungus (491) 93MRSA (539) 85MRZ Reaction (463) 66MSH2 (783) 33MTHFR (732) 24MTHFR C677T (732, 747) 24, 26Mucorales (490) 93Multiple Endocrine Neoplasia Type 2A (738) 28Multiplex Test (430–433) 120, 121Mumps Virus (356, 387) 115, 127Myasthenia gravis (269) 18Mycobacteria (421–427) 96, 97Mycology (490, 491) 93Mycophenolic acid (602) 70Mycoplasma pneumoniae (324, 541) 85, 90Mycoserology (480, 481) 94MYD88 (766) 34

Myocardial Markers (760, 761) 52Myoglobin (760) 52

NN-Desmethylclozapine (200, 862, 863) 70, 74N-Desmethylmethsuximide (192) 69N334K (793) 26Neisseria gonorrhoeae (530) 82Neonatal Bilirubin (110) 56Neuroborreliosis (465) 67Neutrophilic Granulocytes (612) 37Nevirapine (850) 71Newborn screening (785) 76Next Generation Sequencing (580) 86NGS-Analysis (580) 86Nickel (205, 206, 208) 61Nitrazepam (877) 72Nitrite (171) 80NK-cells (213, 617, 651) 20, 38NOD2 (774) 30Nontuberculous mycobacteria (427) 97Norclomipramine (199, 203, 204, 863) 74, 75Nordiazepam (876) 72Nordoxepin (201, 203, 204, 863) 74, 75Norepinephrine (175, 185) 52, 80Normaproptiline (202) 74Normetanephrine (175) 80Noroviruses (381, 430) 116, 120Nortrimipramine (201, 203, 204) 75Nortriptyline (199, 203, 204, 863) 74, 75NSAIDs (194) 68NSE (292) 57NT-pro BNP (760) 52

OO-Desmethylvenlafaxine (860, 861) 73Olanzapine (862, 875) 71, 74Oligoclonal IgG (462) 66Opiate (174) 76Orgaran (282) 42Ornithine (710) 51Osmolality (100, 173) 55, 80Oxazepam (876) 72

Pp-ANCA (257) 17p.D816V (767) 34p.L265P (766) 34PAI-1 (4G/5G) (735, 748) 24, 26Paliperidone (862) 74Pancreas (300) 63Pancreas amylase (100, 120, 173) 55, 79, 80Panel for Viral Meningitis (433) 121Pantothenic acid (Vitamin B5) (290) 58PAP (785) 76PAPP-A (305) 64Paracetamol (194) 68Parainfluenza Viruses (388, 431) 116, 120Paraneoplastic Neuropathies (265) 18Parasite Microscopy (451, 456) 94, 95Parasite Serology (452, 454, 455) 95Parasites (451, 452, 454–456) 94, 95Parechovirus (407, 430, 431, 433) 117, 120, 121Paroxetine (875) 71Parvovirus B19 (342, 367) 116, 128pCO2 (161, 163) 78Pentaporphyrin (178) 81Perazine (860, 874) 71, 73Peripheral Neuropathies (267) 18

150/156

Index

pH (161, 163, 171) 78, 80Phenobarbital (195) 73Phenylalanine (710) 51Phenytoin (195) 73Phosphate (100, 173, 810) 55, 79, 80Phosphoethanolamine (710) 51Phospholipids (151) 55PhosphoTau Protein (pTau) (466) 67Photometer Controls (181) 56Pipamperone (873) 71Piperacilline (890) 69Pituitary (298) 62Placental growth factor (625) 65Plasmaprotein (240–242) 56, 57Plasminogenactivator-Inhibitor

(PAI): 4G, 5G (735, 748) 24, 26Platelet antibodies (233) 99Platelet antigens (233) 99Platelet Immunology (233) 99Platin (206) 61PLGF (625) 65Pneumocystis jirovecii (560) 86PNH (616) 39pO2 (161, 163) 78Porphobilinogen (178) 81Porphyrins (178) 81Posaconazole (198) 70Potassium

(100, 120, 161, 163, 173, 810) 55, 78–80Prader-Willi, Angelman (786) 33Preanalytics (901) 131Preeclampsia Marker (625) 65Pregabalin (872) 70Primidon (195) 73Pro-Gastrin-Releasing Peptide (299) 57Pro-insuline (300) 63Procalcitonin (320) 90Progenitor Cells (217) 38Progesterone (302) 63Prolactin (298) 62Proline (710) 51Prostatic acid Posphatase (100) 55Protease Inhibitors (384) 111Protein

(100, 141, 171,  173, 460, 810) 52, 55, 66, 79, 80

Protein Analysis (460) 66Protein S (225, 791) 29, 41Prothrombin G20210A (731, 746) 24, 26PSA (292, 293) 57Psychostimulants (879) 74Psychotherapeutic Drugs (860–863) 73, 74Pyridoxal-5-phosphate (Vitamin B6)

(290, 291) 58

QQuetiapine (860–862) 73, 74Quick (221, 285, 286) 40, 43, 45

RRabies Virus (336, 390) 118, 128Raltegravir (850) 71Reboxetine (873) 71Respiratory Stimulants (870) 68Respiratory Stimulants (870) 68Respiratory Syncytial Virus (359, 432) 117, 121Respiratory Virus Panel (431, 432) 120, 121Ret Proto-Oncogene (738) 28Reticulated Platelets (216) 37Reticulocyte production Index (RPI) (216) 37

Reticulocytes (215, 216) 37, 38Retinol (Vitamin A) (290) 58Reverse Transcriptase Inhibitors (384) 111Rh - Subtyping (231, 232, 237) 98Rh - Subtyping (without Cw) (238) 99Rh (D) Factor (231, 232, 237, 238) 98, 99RHCE (235) 99RHD - Deletion (235) 99RHD - Deletion (235) 99Rheumatoid Arthritis (273) 19Rheumatoid Factor (323) 91Rheumatoid Factors (273) 19Ribavirine (850) 71Riboflavin (Vitamin B2) (290, 291) 58Rilpivirin (850) 71Risperidone (862) 74Ritalinic acid (879) 74Ritonavir (850) 71Rivaroxaban (503) 44ROMA-Score (292) 57Rotaviruses (430) 120Rotaviruses (401) 117Rubella Virus (341, 389, 463) 66, 118, 128Rufinamide (871) 69S100 (292) 57S65C (741) 27Salicylic acid (194) 68Salmonella (331) 91Salmonella enterica (537) 85Sapoviruses (430) 120Sarcosine (710) 51

SsC5b-9 (247) 59SCC (292) 57Schistosomiasis (454) 95Sediment Pictures (172) 81Selenium (205, 206, 208) 61Serine (710) 51Serotonin (175, 185) 52, 80SERPINC1 (792) 28Sertraline (873) 71Serum Proteins (141) 52sFLT-1

(soluble fms-like tyrosine kinase-1) (625) 65Sirolimus (601) 72SMN1 (787) 33SNRPN (786) 33sO2 (163) 78Sodium (100, 161, 163, 173, 810) 55, 78–80specific gravity (171) 80Spinal Muscular Atrophy (787) 33Staining characteristics (411, 412) 87Staining characteristics (413) 88STAT3 (769) 35Status of hantavirus infection (355) 124STEC (534) 84Stem Cells (217) 38Steroid Homones (302) 63sTfR (241) 56Stool parasites (451) 95Streptococcal AB (321) 91Sulbactam (890) 69Sulthiame (191) 69Susceptibility Testing (425–427) 97Susceptibility tests (411, 412) 87Systematic Toxicological Analysis

(STA) (188) 77

TT-Cells (617, 651) 20, 38T-Helper Cells (651) 20T-lymphocytes (213) 38T3 (294, 302) 63T4 (294, 302) 63Tacrolimus (601) 72Taurine (710) 51Tazobactam (890) 69tCO2 (810) 79Teicoplanin (193) 68Temazepam (877) 72Testosterone (293, 302) 57, 63Tetanus Toxoid (310) 91Tetracyclic Antidepressants (202) 74Theophylline (195) 73Thiamine total (Vitamin B1) (291) 58Thiaminpyrophosphat (TPP) (291) 58Threonine (710) 51Thrombin Generation Test (289) 47Thrombin time (222, 230, 280, 285) 40–43Thrombocytes (209, 211, 612) 36, 37Thrombopoietin (626) 64Thyreoglobulin (292, 301) 57, 62Thyroid Gland Antibodies (295) 63Thyroid Hormones (294, 301, 302) 62, 63Thyroxine (294, 302) 63Tiagabine (872) 70Tick-Borne Encephalitis (358) 123Tin (207) 61Tobramycin (197) 73Tocopherol (Vitamin E) (290) 58Topiramate (872) 70Torque Teno Virus (TTV) (408) 118Total Protein C (225, 790) 28, 41Total Tau Protein (Tau) (466) 67Toxin Gene (545) 83Toxoplasm gondii (457) 96Toxoplasmosis (452) 95TP53 (765) 35TPA (292) 57TPMT (775) 30TPS (292) 57TPT (221) 40TPZ (221, 285, 286) 40, 43, 45Trace Elements (205–208) 61Training Course (470, 901, 902) 131, 132Training Program

(368, 378, 379, 382) 104, 107, 108, 110TRAK/THYBIA (295) 63Transferrine (100, 173, 241) 55, 56, 80Trazodone (876) 72Treponema pallidum (311) 92Tricyclic Antidepressants (199, 201–204) 74, 75Triglycerides (100, 120, 151, 810) 55, 79Trijodthyronin (294, 302) 63Trimipramine (201, 203, 204, 863) 74, 75Trockenchemie (800, 810) 79Tropism Determination (384) 111Troponin I (760) 52Troponin T (760) 52Tryptophan (710) 51TSH (294, 302, 785) 63, 76Tuberculosis (421–427) 96, 97Tumor Markers (292, 293, 299) 57Typing of adenovirus (371) 102Typing of Dengue Viruses (369) 105Typing of enterovirus (372) 105Typing of human rhinovirus (393) 112Typing of measles virus (386) 115Typing of mumps virus (387) 115Typing of parainfluenza virus (388) 116

151/156

Index

Typing of rotavirus (401) 117Typing of rubella virus (389) 118Typing of seasonal and

avian influenza A viruses (370) 114Typing of West Nile virus (391) 119Typing of Zika virus (403) 119Tyrosine (710) 51

UUDP-Glucuronyltransferase 1 (742) 28UF Heparin (280) 42Urea (100, 120, 161, 163, 173) 55, 78–80Urea (810) 79Uric Acid (100, 120, 173, 810) 55, 79, 80Urinary Stone (500) 54Urinary Stone Analyses (500) 54Urine Chemistry

(171–173, 175, 178, 179) 80, 81Urine Sediment (902) 132Urobilinogen (171) 80Urogenital Panel (547) 86Uroporphorin (178) 81

VValine (710) 51Valproic Acid (195) 73Vanadium (207) 61Vancomycin (197) 73Vancomycin Resistant Enterococci (546) 86Vanillylmandelic acid (175) 80Varicella Zoster Virus

(353, 366, 433, 463) 66, 119, 121, 129Vasculitis (257) 17Venlafaxine (860, 861) 73Viable CD34+ events (217) 38Viable CD45+ events (217) 38Vigabatrin (872) 70Virilization (309) 64Virus Detection (370) 114Virus Genome Detection

(340, 349, 359–369, 371–373, 375–397, 399–401, 403–408, 415, 430–433) 102–122

Virus Immunology (335–339, 341–348,  350–358, 402, 415) 122–129

Vitamin C (296) 58Vitamins (187, 290, 291) 58VKORC1 (775) 30VLDL-cholesterol (810) 79Voriconazole (198) 70VRE (546) 86

WWest Nile Virus (391) 119Willebrand Factor (227) 41

YY-Chromosome Microdeletions (788) 34Yeasts (490, 491) 93Yersinia (315) 92

ZZika Virus (338, 403) 119, 129Zinc (205, 206, 208) 61Ziprasidone (862, 873) 71, 74Zonisamide (872) 70

152/156

In cooperation with

Ärzteverband Deutscher Allergologen e. V.

Arbeitsgruppe Therapeutisches Drug Monitoring (AGTDM) der Arbeitsgemeinschaft Neuropsychopharmakologie und Pharmakopsychiatrie e. V. (AGNP e. V.)

Arbeitskreis Mykobakterien

Berufsverband Deutscher Dermatologen e. V.

Deutsche Dermatologische Gesellschaft e. V.

Deutsche Gesellschaft für Hämatologie und Onkologie e. V.

Deutsche Gesellschaft für Hygiene und Mikrobiologie e. V.

Deutsche Gesellschaft für Immungenetik

Deutsche Gesellschaft für Innere Medizin e. V.

Deutsche Vereinte Gesellschaft für Klinische Chemie und Laboratoriumsmedizin e.V.

Deutsche Gesellschaft für Liquordiagnostik und Klinische Neurochemie e.V.

Deutsche Gesellschaft für Mineralstoffe und Spurenelemente e.V.

Deutsche Gesellschaft für Parasitologie e. V.

Deutsche Gesellschaft für Transfusionsmedizin und Immunhämatologie e. V.

Deutsche Gesellschaft für Urologie e.V.

Deutsche Gesellschaft für Zytologie e. V.

Deutsche Vereinigung zur Bekämpfung der Viruskrankheiten e. V.

Deutschsprachige Mykologische Gesellschaft e. V.

ECAT, Voorschoten, Niederlande

Gesellschaft für Thrombose- und Hämostaseforschung e.V.

Gesellschaft für Virologie e. V.

MQ, Zürich, Schweiz

QualiCont, Szeged, Ungarn

Imprint

INSTAND Gesellschaft zur Förderung der Qualitätssicherung in medizinischen Laboratorien e. V.

Ubierstr. 20 40223 Düsseldorf, Deutschland

T +49 [0] 211 1592 13-0 F +49 [0] 211 1592 13-30 E [email protected]

Vertreten durch: Vorsitzender: Prof. Dr. med. Michael Spannagl Stellvertretender Vorsitzender: Prof. Dr. rer. nat. Ingo Schellenberg Stellvertretender Vorsitzender: Prof. Dr. med. Klaus-Peter Hunfeld

Registereintrag: Eingetragen im Vereinsregister. Registergericht: Amtsgericht Düsseldorf Registernummer: VR 10969

Umsatzsteuer-Identifkationsnummer nach § 27a Umsatzsteuergesetz: DE119496290

153/156

Contents by Group Numbers

100 Clinical Chemistry – Conventional Analysis  55102 Capillary Zone Electrophoresis  55110 Neonatal Bilirubin  56111 Glucose – Conventional Analysis  54118 Ammonia  51120 Dry Chemistry 03 – POCT: Relotron Systems  79130 Fecal Diagnostics 01  53131 Fecal Diagnostics 02  53141 Serum Proteins/Electrophoresis  52145 HbA1c  58146 Fructosamine  53151 Lipids/Lipoproteins  55161 Blood Gas Analysis  78162 Blood Gas Analysis – Haemoglobin  78163 Blood Gas Analysis OPTI Systems  78171 Urine Chemistry 01 (Qualitative)  80172 Urine Chemistry 06 (Sediment Pictures)  81173 Urine Chemistry 02 (Quantitative)  80174 Drugs of Abuse in Human Urine 01 (Qualitative+Quantitative)  76175 Urine chemistry 03 (Biogene Amines)  80176 Drugs of Abuse in Human Urine 02 (Qualitative+Quantitative)  76177 Drugs of Abuse in Human Urine 03 (Qualitative+Quantitative)  76178 Urine Chemistry 04 (Porphyrins)  81179 Urine Chemistry 05 (Hormones)  81181 Photometer Controls  56185 Biogenic Amine in Plasma  52187 Vitamins 04 – Methylmalonic Acid  58188 Systematic Toxicological Analysis (STA)  77190 Antiarrhytmics – Amiodaron  68191 Anticonvulsants 01  69192 Anticonvulsants 02  69193 Antibacterials – Teicoplanin  68194 Paracetamol and NSAIDs  68195 TDM 01  73197 TDM 02  73198 Antifungals / Chloramphenicol  70199 Tricyclic Antidepressants 01 – Quantitative in Serum  75200 Antipsychotic Drugs 01  70201 Tricyclic Antidepressants 02 – Quantitative in Serum  75202 Tri-/Tetracyclic Antidepressants 03 – Quantitative in Serum  74203 Tricyclic Antidepressants 04 – Qualitative in Serum  75204 Tricyclic Antidepressants 05 – Qualitative in Urine  75205–208 Trace Elements 01–04  61209 Haematology 03 – Blood Cell Count – QBC System  37210 Haematology 15 – Haemoglobinopathies  39211 Haematology 01 – Blood Cell Count  36212 Haematology 07 – Blood Smear Analysis  36213 Haematology 10 – Immunophenotyping 01  38214 Haematology 12 – Immunophenotyping 02  39215 Haematology 05 – Reticulocyte Analysis 01 (Microscopy)  38216 Haematology 04 – Reticulocyte Analysis 02 (Machine-Based Analysis)  37217 Haematology 11 – Stem/Progenitor Cells (CD 34)  38218 Haematology 09 – Bone Marrow Cytology  36220–230 Haemostasis 01–11  41–46231 Immunohaematology 01  98232 Immunohaematology 02  98233 Immunohaematology 03 – Platelet Immunology  99234 Immunohaematology 04 – Granulocyte Immunology  100235 Immunohaematology 06 – Molecular Diagnostic  99236 Haematology 16 – Free Haemoglobin  37237 Immunohaematology 05 (Machine-Based Analysis)  98238 Immunohaematology 07 (Machine-Based Analysis)  99240 Plasmaproteins 03 – hsCRP  57241 Plasmaproteins 01  56242 Plasmaproteins 02 – Cystatin-C  56243 Gammopathies  54244 IgG Subclasses  54245–250 Complement Analysis 01–06  58–59251–275 Autoimmune Diseases 01–13  16–19280–289 Haemostasis 12–15, 17–20, 24  42–47290 Vitamins 01 (Serum)  58291 Vitamins 02 (Whole Blood)  58292 Tumor Markers  57293 Tumor Markers – PSA and Testosterone  57

294 Hormones – Thyroid Hormones  63295 Hormones – Thyroid Gland Antibodies  63296 Vitamins 03 – Vitamin C  58297 Hormones – Fertility  62298 Hormones – Adrenal Gland/Pituitary  62299 Tumor Markers – Calcitonin/Pro-Gastrin-Releasing Peptide  57300 Hormones – Pancreas/Gastrointestinal Tract  63301 Hormones – Calcium Metabolism / Special Thyroid  62302 Hormones – Steroid Homones, Thyroid Gland  63304 Hormones – Aldosterone  62305 Hormones – Gravidity – 1st Trimester Screening  64306 Hormones – Gravidity – 2nd Trimester Screening  64309 Hormones – Virilization  64310–334 Infection Serelogy  51, 88–92335–339, 341–348, 350–358, 402, 415  Virus Immunology  122–129340, 349, 359–397, 399–401, 403–408  Virus Genome Detection  102–121411 Bacteriology – 3 Strains  87412 Bacteriology – 5 Strains  87413 Bacteriology – Gram Stain  88421–426 Mycobacteriology 01–06  96–97427 Mycobacteria Diagnostics 01  97430–433 Multiplex Tests  120–121440–445 Immunogenetics – HLA  21–23451 Parasite Microscopy (Stool)  95452 Parasite Serology – Toxoplasmosis  95454 Parasite Serology – Malaria and Schistosomiasis  95455 Parasite Serology – Amoebiasis and Echinococcosis  95456 Parasite Microscopy (Blood)  94457 Detection of Toxoplasma DNA (PCR)  96460, 462–466 Cerebrospinal Fluid Analysis 01–06  66–67470 Cerebrospinal Fluid Cytology Course  131480 Mycoserology 01 – Candida (Antigen+Antibodies)  94481 Mycoserology 02 – Cryptococcus neoformans/ – gattii Antigen  94490 Mycology 01 (Mucorales, Yeasts, Coelomycetes, Hyphomycetes, Basidiomycetes)  93

939454

43–4982–86

867270373938

656450932019535116

23–2425–29

50505252

34–3529–34

35777979

7173–7468–74

69

491 Mycology 02 (Dermatophytes, Yeasts, Mould Fungus) 492 Genome Detection of Dermatophytes 500 Urinary Stone Analyses 501–505, 509–514  Haemostasis 21–23, 25–32 530–547, 580  Bacterial Genome Detection 560 Fungal Genome Detection – Pneumocystis jirovecii 601 Immunosuppressants 602 Antifungals / Immunosuppressants 612 Haematology 06 – Differential Blood Count (Machine-Based Analysis)  616 Haematology 13 – PNH Diagnostics 617 Hämatologie 14 - Immunphänotypisierung 03 

625 Preeclampsia Marker 626 Hematopoetic Growth Factors 630 ACE (Angiotensin-Converting-Enzyme) 650 Interferon Gamma Release Assay (IGRA) 651 Cellular Immunodeiciency Diagnostic (Cytometry) 653 Basophil Activation Test 700 Ethanol 710 Amino Acid Analysis 720 Allergy Diagnostic 730–735 Molecular genetics 01 738–749,790–793 Molecular genetics 02 750 Markers of Ethanol Abuse 01 751 Markers of Ethanol Abuse 02 760 Myocardial Markers 761 Myocardial Markers BNP 765–769 769 Molecular onkology 770–784,786–788 Molecular genetics 03 794 Molecular genetics 04 785 Newborn Screening 800 Dry Chemistry 01 – POCT: Glucose 810 Dry Chemistry 02 – POCT: Abaxis Piccolo System 

850 Antivirals 860–863 Psychotherapeutic Drugs 01–04 870–879 TDM 890 Antibacterials 02 901–902 Online Training  131–132

Gesellschaft zur Förderung der Qualitätssicherung in medizinischen Laboratorien e. V.

Ubierstr. 20 40223 Düsseldorf, Germany

T +49 [0] 211 1592 13-0

F +49 [0] 211 1592 13-30 E [email protected] I www.instand-ev.de

INSTAND - 00 complete databaseinterlab.lt/image/data/PDF/Instand 2020.pdf · Molecular genetics 01...

Documents

Transcript of INSTAND - 00 complete databaseinterlab.lt/image/data/PDF/Instand 2020.pdf · Molecular genetics 01...