SUPPLEMENTARY DATA

Participating centers

AustriaBregenz: Institut fur Reproduktionsmedizin und EndokrinologieDobl: Kinderwunschinstitut SchenkFeldkirch: Kinderwunschzentrum Landeskrankenhaus FeldkirchGraz: Institut fur In-Vitro-Fertilisierung und Endokrinologie; Institutfur Hormonstorungen Wechselbeschwerden und Kinderwunsch;A. o. Landeskrankenhaus GrazHorn: Landesklinikum Waldviertel HornInnsbruck: Landeskrankenhaus-Universitatskliniken Innsbruck; PrivateKinderwunschklinik Dr Josef Zech GmbH; WOMED TherapiezentrumKinderwunsch GmbHKlagenfurt: Sterignost Kinderwunschbehandlungs GmbHKrumpendorf: Privatkrankenanstalt ParkvillaLinz: Landes-Frauen- und KinderklinikOberpullendorf: A. O. Krankenhaus OberpullendorfSt. Polten: Landesklinikum St. PoltenSalzburg: IVF-Zentren Prof. Zech Salzburg GmbH; LandeskrankenhausSalzburg—Universitatsklinikum der PMU; Babywunsch-Klinik Dr ZajcGmbHVienna: Allgemeines Krankenhaus der Stadt Wien; Goldenes Kreuz;GYNANDRON Dr Freude; Krankenhaus Hietzing mit NeurologischemZentrum Rosenhugel; Wunschbaby-Zentrum, Institut fur Kinder-wunsch; Adebar—Institut fur Reproduktionsmedizin und Psychosoma-tik der Sterilitat; Privat Klinik Wien Wahring; Fertilitatszentrum DoblingWels-Thalheim: Die KinderWunschKlinik Dr Loimer GmbH

BelgiumAntwerpen: Dienst Fertiliteit, Algemeen Ziekenhuis MiddelheimBraine—L’alleud: Centre de Fecondation C.H. Interregional Edith Cavell(CHIREC),Brugge: BIRTH—Fertiliteitskliniek, Algemeen Ziekenhuis Sint-JanBrussel: Centrum voor Reproductieve Geneeskunde, UZ Brussel; Clin-ique de Procreation Medicalement Assistee, Hopital Universitaire Saint-Pierre—U.L.B.; Service de Gynecologie, Cliniques UniversitairesSaint-Luc—U.C.L.; Centre de FIV de l’U.L.B.—Hopital ErasmeCharleroi: Service Gyn/Obst, Clinique Notre DameEdegem: Centrum voor Reproductieve Geneeskunde, Universitair Zie-kenhuis Antwerpen—U.I.A.,Genk: Centre for Reproductive Medicine, Ziekenhuis Oost-Limburg—St. Jan

Gent: Vrouwenkliniek- Infertiliteitscentrum, U.Z.—Gent; Centrumvoor Fertiliteitstherapie, A.Z. Jan PalfijnLeuven: dienst Gynaecologie, Universitaire Zieknhuizen K.U.LeuvenGasthuisberg; Unit Reproductieve Geneeskunde, Regionaal ZiekenhuisHeilig HartLibramont: Centre d’Infertilite, Centre Hospitalier de l’ArdenneLiege: Centre de FIV, Centre Hospitalier Regional de la CitadelleNamur: Service Gyneco, Centre Hospitalier Regional de NamurRocourt: Centre Liegeois pour l’etude et le traitement de la sterilite,Clinique Saint Vincent

BulgariaPleven: Clinical Institute for Reproductive MedicinePlovdiv: Medical center ‘BORA’Sofia: In Vitro Gynecological center ‘Todorov Brothers’; In Vitro Medicalcenter ‘J Dimitrov’; Ob/Gyn Hospital ‘Dr Shterev’Varna: Medical Center for assisted reproduction ‘Varna’; Medical Center‘Olimed’; Medical Center ‘Maichin Dom’

Czech RepublicBrno: MUDr. Ales Bourek; REPROMEDA, s.r.o.; Sanatorium HELIOS,s.r.o.; CAR01 Brno, Gyn.—por. klinika FN Brno; UNICA, s.r.o.; ReprofitInternational s.r.o.Ceske Budejovice: Sanatorium ART, s.r.o.Hradec Kralove: SANUS, s.r.o.Jihlava: Sanus JihlavaKarlovy Vary: Institut reprodukcnı medicıny a genetiky, s.r.o.; PronatalSPA, s.r.o.Kostelec nad Orlicı: ARLETA IVF, s.r.o.Liberec: Gennet LiberecOlomouc: Fakultni nemocnice Olomouc, CAR, Por.-gyn. Klinika; FER-TIMED, s.r.o.Ostrava: GYNCENTRUM Ostrava, s.r.o.Pardubice: SANUS PardubicePlzen: Fakultnı nemocnice Plzen, CAR, Gyn.-por. Klinika; IVF—ZentrenProf. Zech—Pilsen s.r.o.; NATALART, s.r.oPraha: Fakultnı nemocnice v Motole, CAR, Gyn.- por. klinika 2. LF UK;GENNET, s.r.o. Praha; GEST, s.r.o.; ISCARE I.V.F., a.s.; PRAGUEFERTILITY CENTRE s.r.o.; Pronatal Plus, s.r.o.; PRONATAL, s.r.o.;Ustav pro peci o matku a dıte; Vseobecna fakultnı nemocnice v Praze,CAR, Gyn.- por. klinika 1. LF UK

& The Author 2014. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email:journals.permissions@oup.com

Human Reproduction, Vol.0, No.0 pp. 1–33, 2014doi:10.1093/humrep/deu175_suppl

Teplice: Pronatal Nord, s.r.oZlın: IVF Czech Republic, s.r.o.

DenmarkAalborg: Faurskov Fertilitet og UltralydAarhus: Aagaard Fertilitetsklinik; Privathospitalet Ciconia; Fertilitetskli-nikken Skejby Sygehus; Maigaards FertilitetsklinikBrædstup: Fertilitetsklinikken Brædstrup SygehusCopenhagen: Dansk Fertilitetsklinik; Fertilitetsklinikken IVF; Fertilitetsk-linikken Herlev Sygehus; Fertilitetsklinikken Hvidovre Hospital; Fertili-tetsklinikken Rigshospitalet; Fertilitetsklinikken Trianglen; CopenhagenFertility Center; VitaNovaDronninglund: Fertilitetsklinikken DronninglundFredericia: IVF-SYDHolbæk: Fertilitetsklinikken Holbæk SygehusOdense: Fertilitetsklinikken Odense Universitetshospital; OdenseIVF-KlinikSkive: Fertilitetsklinikken Skive Sygehus

FinlandHelsinki: Family Federation of Finland Helsinki; Felicitas; Fertinova;Graviditas; Helsinki University Central HospitalJoensuu: Northern Carelia Central HospitalJyvaskyla: In-Tiimi JyvaskylaKuopio: In-Tiimi Kuopio; Kuopio University Central HospitalLappeenranta: FelicitasOulu: Family Federation of Finland Oulu; Oulu University CentralHospitalTampere: AVA Tampere; Ovumia; Tampere University Central HospitalTurku: AVA Turku; Family Federation of Finland Turku; Turku UniversityCentral Hospital

FranceAgen: LBM G 2 BIO; LBM Olivot MariottiAix en Provence: Site d’Aix en Provence, lbm Celse l’Hoste; Lbm SoletLlorca, site Aix en Provence, Lbm CardinalAmiens: Groupe Sante Victor Pauchet; Centre De Gyneco ObstetriqueCHU AmiensAngers: C.H.U. D’ Angers; Lbm AndebioAngouleme: Laboratoire Labio 16 (2)Annecy: Lbm Biolac site Annecy; Labm Goguey Lorenter JouvalAnnemasse: Hopital de Bonneville, lbm BioalpAntibes: Lbm SoleauAntony: Labm Selas Laboratoires Velpeau; Lbm Novescia SiteVelpeauArgenteuil: Centre Hospitalier Victor DupouyAuxerre Lbm Selas des Cordeliers ClairionsAvignon: Polyclinique Urbain V, Lbm Biotop site Maison d’ AsclepiosBagnolet: Clinique de La Dhuys, Selafa Labm ZTPBar le Duc: Lbm ‘Syndibio’ MonvoisinBastia: Lbm Vialle site de LupinoBayonne: Capio Clinique Lafargue, lbm ‘Ax Bio Ocean’Beaumont: Clinique La ChataigneraieBergerac: Lbm NovabioBesancon: CHU Saint Jacques; Polyclinique de Franche-Comte

Beziers: Lbm Labosud OC Biologie Beziers BITERRBollene: Labm Martin Pertris BolleneBondy: Hopital Jean VerdierBordeaux: Groupe Hospitalier Pellegrin CHU; Polyclinique Jean Villar,Lbm ‘Bioffice’Bourg en Bresse: Labm Bretin MegevandBrest: CHRU hopital Morvan; Clinique Pasteur LanrozeBrive la Gaillarde: Lbm Bioreze Brive Berthelot; Labo Leymarie LabroChambonBron: Hopital femme Mere EnfantBussy Saint Georges: Lbm ‘Bio vsm lab’Caen: CHU Cote De Nacre CAEN; Labm MalherbeCalais: CH Calais; Laboratoire Principal Centre biologiqueCannes: Labm DemesCastres: Lbm Novescia Midi-PyreneesCayenne: Centre Hospitalier de CayenneCernay: Labm MonnierChalon sur Saone: Biolab Unilabs Chalon BoucicautChambery: Lbm MS Laboschambery Chambery SiegeChambray-Les-Tours: Pole Sante Leonard de Vinci/ Lbm l’Abo+Chambray Leonard de VinciChampigny Sur Marne: CHI de Creteil, lbm BiomegaCharleville-Mezieres: Hopital Manchester CH Charleville; Lbm BioArd’AisneCholet: Lbm Xlabs; Lbm BiomelisClamart: Hopital Antoine Beclere; Labm Benhaim site Jean JauresClermont-Ferrand: CHU EstaingColmar: Lbm Barrand AlsaceCompiegne: Lbm Biocome Compiegne BernardCormeilles En Parisis: Clinique du ParisisCoutances: Lbm Multi sites BiocentreCreteil: Lbm Bio Epine Site Creteil SoleilDax: Lbm Forte BioDijon: Hopital Le Bocage CHU Dijon; Lbm Biopole 21 dijon Vaillant; LbmBruant DijonDraguignan: Labm Cammilleri Poillon VilleDreux: CH DreuxDunkerque: Laboratoire PrincipalEnghien Les Bains: Lbm Bio Paris Ouest Site EnghieneEpinal: Clinique L’Arc en cielEqueudreville Hainneville: Polyclinique du CotentinErmont: Clinique Claude BernardFlers: CH Jacques Monod FlersHenin Beaumont: Laboratoire Secondaire Griere LobryKaysersberg: Lbm Cab site VignobleLa Roche sur Yon: Lbm BiorylisLa Rochelle: Clinique du Mail La RochelleLa Tronche: Hopital NordLannion: Labm. Labazur ArmoriqueLaval: Lbm BiolarisLe Blanc Mesnil: Hopital Prive De La Seine Saint Denis/Lbm ClementFresnais Hamidi MinzLe Chesnay: Centre Medico Chirurgical de Parly IILe Coudray: CH Chartres Louis Pasteur Le CoudrayLe Havre: Hopital Jacques Monod Ch Le Havre/Labm Rocaboy andChevallier HelasLe Mans: Clinique du Tertre Rouge

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Le Port: Clinique Jeanne d’ArcLens: CH LensLes Abymes: CHU de Pointe a Pitre/AbymesLibourne: Lbm AquilabLille: Polyclinique du Bois; Hop Jeanne de Flandre CHR Lille; LaboratoireSecondaire BiolilleLimoges: CHU Dupuytren Limoges; Labm BiolyssL’Isle d’Abeau: Lbm NovialeLorient: Centre Hospitalier Bretagne SudLyon 2ieme: Lbm DyomedeaLyon 7ieme: Clinique Du Val d’Ouest Vendome, laboratoire Biomnis;Clinique du Tonkin, Laboratoire biomnisLyon 8ieme: Hop Prive Mere Enfant Natecia/Lbm Novescia RhoneAlpesMacon: Lbm MedilabsMarseille 5ieme: APHM Hopital de la ConceptionMarseille 8ieme: Hopital St Joseph; Clinique Bouchard, Lbm GiorgettiMarseille 12ieme: Lbm JS BioMetz: Hopital Maternite de Metz,/Labm ‘Espacebio’ Stahl KuntzelMont de Marsan: Lbm Landes Biologie MedicaleMontauban: Lbm Bio FusionMontpellier: Hopital Araud de Villeneuve CHU MPT; Polyclinique SaintRoch;Mulhouse: Clinique Diaconat Roosevelt, Lbm du Diaconat; Lbm Cab sitePegon; Hopital Emile MullerNancy: Polyclinque Majorelle; Maternite Regionale A Pinard; CHUNantes site Hotel Dieu Hme; Clinique Breteche; Clinique J.Verne PoleHosp mutualisteNantes: C.H.U. Nantes Hotel Dieu et hoe; Clinique Breteche Viaud SiteBreteche; Clinique J. Verne Pole Hosp mutualisteNeuilly sur Seine: Hopital Americain; CH de Courbevoie Neuilly PuteauxNevers: Lbm Scp G.Ferrand NeversNice: Labm Delpech Zerbib; Clinique Saint Georges; Chu De NiceHopital De L’archetNimes: Groupe Hospitalier Caremeau CHU Nimes; Lab.FourquetGoulesque; Laboratoire Bebin CabrolNiort: Laboratoire Medilab Group (4) SOrleans: Centre Hospitalier regional d’Orleans; Labm SELASBiosyntheseParis 5ieme: Lbm Selas Sante Bio Site Saint GermainParis 9ieme: Hopital Des Diaconesses/Labm Drouot; Hopital PierreRouques ‘Les Bluets’/Labm DrouotParis 10ieme: Labm MagentaParis 13ieme: Groupe Hosp. Pitie SalpetriereParis 14ieme: Hopital Cochin St Vincent Paul; Institut mutualiste Mon-tsouris; Lbm Bio Epine Site Denfert; Lbm Selas Cbcv Site Bd Saint JacquesParis 15ieme: Lbm La ScalaParis 16ieme: Clinique de La Muette; Lbm Eylau Unilabs Site Saint Didier;Ctre Chirurgical Pierre Cherest/Lbm Eylau Unilabs Site Saint DidierParis 18ieme: G.I.H. Bichat/Claude BernardParis 19ieme: Lbm Bio Path CrimeeParis 20ieme: Hopital TenonPau: Polyclinique de NavarrePerigueux: Polyclinique FranchevillePerpignan: Clinique Saint PierrePointe a Pitre: Laboratoire Espiand GirardPoissy: C.H. Int. De Poissy/St Germain en Laye

Poitiers: CHU La MiletrieQuimper: Chic. Quimper; Lbm Ty BioReims: Polyclinique de Courlancy/Lbm ‘Courlancy’; Polyclinique deCourlancy/Lbm de la Porte de Paris; Hopital Maison Blanche CHRReims; Hopital Manchester CH Charleville/Lbm de la Porte de ParisRennes: C.H.R. Hopital Sud; Clinique mutualiste La SagesseRoanne: Ch De Roanne/Lbm Glbm Roanne/TanneriesRodez: Lbm Cayrou Gorse BourjeiliRouen: Hopital Charles Nicolle CHU Rouen; Clinique Mathilde Rouen/Lbm Multi Sites Bio SeineSaint Brieuc: Labo. Curunet GeoffroySaint Herblain: Polyclinique de L’AtlantiqueSaint Malo: Lbm Bio Emeraude St Malo DesillesSaint-Martin de Boulogne: SAS Centre M.C.O. Cote D’OpaleSaint Martin d’Heres: Clinique BelledonneSaint Nazaire: Centre hospitalier de St. NazaireSaint Pierre: GHRS ReunionSaint Priest en Jarez: Hopital NordSaintes: Laboratoire Cerdibio CharentesSarreguemines: Labm ‘Medilab est’Schiltigheim: SIHCUS/CMCOSchoelcher: Clinique Sainte MarieSenlis: CH GHPSO Senlis/Lbm Biomag SenlisSens: Labm Dehenry MelinSevres: Ch Des 4 Villes Site SevresSoissons: Centre Hospitalier de SoissonsStrasbourg: Lbm des Vosges; Lbm KlumppTarbes: Lbm Top BioThiais: Lbm Bio EpineToulon: Clinique Saint Michel/Labm Cohen BilliemazToulouse: Hopitaux Mere & Enfants Chu Tlse/Hopitaux Mere & EnfantsChu Tlse; Clinique De L’union/Lbm Montagut Rousselle De Mas; LbmCedibio Unilabs; Clinique Saint Jean Languedoc/Lbm MontagutRousselle De MasTours: C.H.R.U. Bretonneau ToursTroyes: Labm BiolaviValence: Clinique Pasteur/Labm de ClercqValenciennes: Clinique du Parc/Laboratoire Principal BiogroupVannes: Lbm Ocealab Site Kerlann VannesVillefranche sur Saone: Labm Ingels VignonVitry Sur Seine: Clinique des Noriets/Lbm Bio Path VitryS/Seine

GermanyAachen: Frauenarztpraxis mit Schwerpunkt Gynakologische Endokrino-logie und Reproduktionsmedizin, Dr med. Klaus-Michael Grunwald,Aachen; Universitats-Frauenklinik fur Gynakologische Endokrinologieund Reproduktionsmedizin, Med. Fakultat der RWTH Aachen, Prof.Dr med. Joseph Neulen, Dr med. Benjamin Rosing, Dr rer. nat. UteWeißenborn, AachenAalen: Aalener IVF-Zentrum, Dr Rainer Rau, Dr Birgit Schroppel,Dr Roland Eid (Biologe), AalenAugsburg: IVF-Zentrum Augsburg, Dr med. K.-F. Hiller, Dr med. T. H.Bauer, Dr H. Kraus, AugsburgBad Munder: Deutsche Klinik Bad Munder, Zentrum fur Reproduktions-medizin, MVZ wagnerstibbe GmbH, Bispink, Chandra, Breitbach,Hinrichsen, Peper, Bad Munder

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Bayreuth: Klinik am Hofgarten, Kinderwunschzentrum Bayreuth, DrStefan Todorow, BayreuthBedburg/Erft: Gemeinschaftspraxis Dr med. Dieter Struller, Dr med.Christof Etien, BedburgBerlin: Arbeitsgruppe Endokrinologie & Reproduktionsmedizin imLutzow Center, Dr med. Detlef H.G. Temme and Kollegen, Berlin; Fer-tility Center Berlin, Prof. Dr med. H. Kentenich, Dr med. A. Siemann, Drmed. G. Stief, Dr med. A. Tandler-Schneider, Berlin; FrauenarztpraxisKinderwunschzentrum Helle Mitte, Berlin; Kinderwunschzentrum amInnsbrucker Platz Berlin, Babette Remberg, Dr med. Susanne Tewordt-Thyselius, Gyn. Endokrinologie und Reproduktionsmedizin, Berlin; Kin-derwunschzentrum an der Gedachtniskirche, Dr Matthias Bloechle, DrSilke Marr in Praxisgemeinschaft mit der Gemeinschaftspraxis DrHanadi Awwadeh, Dr Anja Mutz in Praxisgemeinschaft mit derGemeinschaftspraxis Dr Birgit Roth, Carola Kadgien, Berlin; Kinder-wunschzentrum Berlin, Akademische Lehrpraxis der Charite Universi-tatsmedizin, Frauenarztliche Gemeinschaftspraxis Dr med. ReinhardHannen, Dr med. Christian F. Stoll, Berlin; KinderwunschzentrumFERA im Wenckebach-Klinikum, Dr Andreas Jantke, Dr SofiaSpindeldreher, Dr Anna Stegelmann, Dr Manzoor Nowshari, Berlin;Praxisklinik fur Fertilitat, Dr med. Peter Sydow/Dr med. DavidJ. Peet, Dr med. Carmen Sydow, Dr med. Ulrike Bergmann-Hensel,Berlin; Universitatsmedizin Berlin Charite—Kinderwunschzentrum,Dr med. B. Pfuller, Dr med. J. Bartley, Dr med. I. Scheiber, Dr rer.nat. H. Schmiady, BerlinBielefeld: Bielefeld Fertility Center, Paul A. Ebert, Dr Karl Volklein, BeataSzypajlo, Zentrum fur Reproduktionsmedizin und GynakologischeEndokrinologie, Bielefeld; Bielefelder Institut fur Fortpflanzungsmedizin—BIF, Dr Beate Harms, Dr Nabaz Baban, BielefeldBocholt: Fertility Center Munsterland, Dr med. Ulrich Hilland, BocholtBochum: VITRO-MED Kinderwunschzentrum Bochum, YvonneGiesner, BochumBonn: Abteilung fur Gynakologische Endokrinologie und Reproduktions-medizin, Universitatsklinikum Bonn, Prof. Dr med. Hans van der Ven,Prof. Dr med. Katrin van der Ven, Dr med. Ulrike Bohlen, Prof. Dr rer.nat. Markus Montag, Bonn; Praxisklinik fur gynakologische Endokrinolo-gie und Reproduktionsmedizin, Priv.-Doz. Dr med. Gernot Prietl,Bonn-Bad GodesbergBremen: Bremer Zentrum fur Fortpflanzungsmedizin (BZF), Dr OlafDrost, Prof. Dr Ernst Heinrich Schmidt, Bremen; KinderwunschBremen, Dr Achim v. Stutterheim, Tanja Finger, Dr Susanne Meyer-Stroh, BremenChemnitz: Kinderwunschzentrum Leipzig—Chemnitz, Dres. P.Jogschies, D. Geistert, L. Shugair, A. Lahl; Kinderwunschzentrum Prax-isklinik City Leipzig, Standort Chemnitz, Dr med. Astrid Gabert, Drmed. Katharina Bauer, Dr med. Georg SaagerDarmstadt: Kinderwunschzentrum Darmstadt, Prof. Dr med. G.Leyendecker, Dr med. A. Bilgicyildirim, Dr med. M. Inacker, DarmstadtDeggendorf: Kinderwunschzentrum Niederbayern, Dr med. HansJ. Kroiss, Dr med. E. Bernhardt, Dr med. Anja Brauker, Dipl. BiologinHeike Vornehm, Edith Wilhelm, DeggendorfDortmund: Kinderwunschzentren Dortmund u. Siegen, Gemeinschaft-spraxis Prof. Dr med. Stefan Dieterle, Dr med. Andreas Neuer, Prof.Dr med. Robert Greb, Dortmund und SiegenDresden: Praxisklinik Dr med. Hans-Jurgen Held, Dresden; Universi-tatsklinikum Carl Gustav Carus Dresden—Klinik und Poliklinik fur

Frauenheilkunde und Geburtshilfe, Prof. Dr med. W. Distler, Dr rer.nat. G. Keck, Dr med. E. Gouma, DresdenDusseldorf: UniKiD, Universitares interdisziplinares Kinderwunschzen-trum Dusseldorf, Frauenklinik der Heinrich-Heine-Universitat, Prof. Drmed. Jan-Steffen Krussel, Dr med. Alexandra Hess, Dr med. BarbaraMikat-Drozdzynski, Dr med. Andrea Schanz, Dr rer. nat. Jens Hirchen-hain, Dusseldorf; Zentrum fur interdisziplinare Kinderwunschbehan-dlung Dusseldorf, Dr M. Scholtes, Ph. D., Dipl.-med. K. Marx,Priv.-Doz. Dr med. S. Kißler, Dr med. Martina Behler, Drmed. S. Pfeiffer, Dr med. Petra Hubert, Tanja Emde, Dr med. SelmaYildirim-Assaf, DusseldorfErlangen: Gemeinschaftspraxis der Frauenarzte, Zentrum fur Reproduk-tionsmedizin, Dr Miklos Hamori, Dr Rolf Behrens, Dr Andreas Hammel,Erlangen; Kinderwunschzentrum Erlangen, Dr med. J. Van Uem, Erlan-gen; Universitats-Fortpflanzungszentrum Franken (UFF), Prof. Drmed. M. W. Beckmann, PD Dr med. Andreas Muller, Prof. Dr rer. nat.Ralf Dittrich (Biologe), ErlangenEssen: NOVUM—Zentrum fur Reproduktionsmedizin Essen—Duis-burg, Prof. Dr T. Katzorke, Dr Dirk Propping, Dr Susanne Wohlers,Prof. Dr P. Bielfeld, EssenEsslingen: IVF-Zentrum Esslingen, Dr med. J. E. Costea, EsslingenFrankfurt/Main: Fertilitatszentrum und Gynakologische Endokrinologie,Universitatsfrauenklinik Frankfurt am Main, PD Dr med. Inka Wiegratz,Frankfurt am Main; Kinderwunschzentrum Frankfurt am Main, am Kran-kenhaus Nordwest, Prof. Dr med. E. Merz, Frankfurt am Main; Zentrumfur Reproduktionsmedizin, Prof. Dr Ernst Siebzehnrubl, Dr AnjaWeidner, FrankfurtFreiburg: Centrum fur Gynakologische Endokrinologie & Reproduk-tionsmedizin Freiburg (CERF), Gemeinschaftspraxis Dr Weitzell, DrThiemann, PD Dr Wetzka, Prof. F. Geisthovel, Freiburg; Klinik fur Endok-rinologie u. Reproduktionsmedizin, Universitats-Frauenklinik Freiburg,Dr S. Friebel, Dr A. Hanjalic-Beck, Prof. H.P. Zahradnik, FreiburgGelsenkirchen:KinderwunschpraxisGelsenkirchen,Drmed.UteCzeromin,Dr med. Ina Walter-Gobel, Dr med. Kathrin Fißeler, GelsenkirchenGottingen: Georg-August-Universitat Gottingen, Prof. Dr med. DrBernd Hinney, Prof. Dr Hans-Wilhelm Michelmann, Gottingen; Kinder-wunschzentrum Gottingen, Dr Rudiger Moltrecht, Dr Sabine Hubner,Dr Thomas Welcker, Dr Filiz Sakin-Kaindl, Dr Stephanie Mittmann, DrPeter Schulzeck, Gottingen; Kinderwunschpraxis Gottingen, Reproduk-tionsmedizin/Gynakologische Endokrinologie, Dr med. Monica Tobler,Jana Rostek, GottingenGrevenbroich: green-ivf: Grevenbroicher Endokrinologikum & IVF-Zentrum, Dr J. Tigges, Dr K. Friol, PD Dr C. Gnoth, GrevenbroichHalle/Saale: Zentrum fur Reproduktionsmedizin und Andrologie (ZRA),Universitatsklinikum Halle (Saale), Univ.-Prof. Dr med. HermannM. Behre, Dr med. Petra Kaltwaßer, Dr rer. nat. Ewald SeligerHamburg: Endokrinologikum Hamburg, Zentrum fur Hormon- undStoffwechselerkrankungen, Reproduktionsmedizin und PranataleMedizin, Hamburg; Kinderwunschzentrum Altonaer Straße, GMPDres. med. Bispink, Horn, Michel u. Partner, Dr Bispink, Dr Horn, DrMichel, Dr Gohmann, Dr Aytekin, Dr Acar-Nosit, Hamburg; Kinder-wunschzentrum Fleetinsel Hamburg, Dr med. Semsettin Kocak, Drmed. Peter List, Dr med. Uwe Weidner, Hamburg; MVZ FertilityCenter Hamburg GmbH, Dr R. Fischer, HamburgHannover: Kinderwunschzentrum Langenhagen—Wolfsburg, Dr MartinaMuseler-Albers, Horst Peter Arendt, Dr Klaus Buhler, Dr Thilo Schill,

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Langenhagen und Wolfsburg; Med. Hochschule Hannover, IVF-Labor, Fr.Dr Schippert, Fr. Dr Baßler, Hannover; Team Kinderwunsch Hannover,Dr Sayme und Kollegen, Werner Hoppenstedt, HannoverHeidelberg: Kinderwunschzentrum Heidelberg, Dr WaltraudParta-Kehry, Dr Suat Parta, Friederike Tesarz, Dr Daniela Seehaus,Dr Christina Thone, Heidelberg; Universitats-Frauenklinik Heidelberg,Gynakologische Endokrinologie und Fertilitatsstorungen, Prof. DrThomas Strowitzki, PD Dr Bettina Toth, HeidelbergHildesheim: Zentrum fur Reproduktionsmedizin u. Humangenetik Hil-desheim, Dres. med. Algermissen, Justus, Wilke, Graf, HildesheimJena: Reproduktionsmedizinisches Zentrum Jena, Priv.-Doz. Dr med.habil. Heidi Fritzsche, Dipl.-med. Jens-Peter Reiher, Dr med. AngelaHoffmann; Universitatsfrauenklinik Jena, Prof. Dr med. Jurgen Weiss,Dr rer. nat. Ines HoppeKarlsruhe: Karlsruher IVF-Programm, AG fur Fortpflanzungsmedizin,Frauenarztpraxis H.J. Graber, Dr V. Wetzel, Dr F. Tetens, LaborarzteDr M. Linnemann und Kollegen, Humangenetik Dr G. Schluter, KarlsruheKassel: MVZ fur Reproduktionsmedizin am Klinikum Kassel, Dr med.Marc Janos Willi, Dr med. Oswald Schmidt, Prof. Dr med. MiguelHinrichsen, KasselKempten: KWK—KinderWunschKempten, Zentrum fur Reproduk-tionsmedizin, Klinik fur Frauenheilkunde und Geburtshilfe, Klinikum—Kempten gGmbH, Prof. Dr med. Ricardo Felberbaum, OA GerhardAllgayer, Dr med. Daniela Hiltensberger, Dipl. Biol. Mohammad Kou-sehlar, KemptenKiel: fertilitycenterkiel, Priv.-Doz. Dr Soren von Otte, Dr Volker Schulz,Dr Martin Volckers, Dr Heike Eckel, Kiel; Kinderwunschzentrum amUK-SH, Campus Kiel, Dr Andreas Schmutzler, Prof. Dr Ali Salmassi,Kiel; Kinderwunsch Kiel, Dr med. K. Brandenburg, Dr sc.agr. A. Bonhoff, Dr med. A. Carstensen, KielKoln: Kinderwunschzentrum-Koln Praxis und Klinik Schoenhauserstraße,Dr med. Markus Merzenich, Kinderwunschzentrum Koln Eva, Schwahn,Koln; PAN Institut fur Endokrinologie u. Reproduktionsmedizin,Dr Stefan Palm, Dr Irene Putz, Dr Mirko Dannhof, Prof. Dr ChristophKeck, Priv.-Doz. Dolores Foth, Koln; Uniklinik Koln, Klinik und Poliklinikfur Frauenheilkunde und Geburtshilfe, Dr G. Rahimi, Dr C. Moers,I. Orth, KolnLeer: Zentrum fur Reproduktionsmedizin, Gyn, Dr med. Wolfgang vonder Burg, LeerLeipzig: Zentrum fur Reproduktionsmedizin, Gynakologische Endokri-nologie und Sexualmedizin, Prof. Dr med. H. Alexander,Dipl.-Biol. W. Weber; Kinderwunschzentrum Leipzig-Chemnitz, Dres.F.A. Hmeidan, P. Jogschies, D. Geistert L. Shugair, A. Lahl; Kinder-wunschzentrum Praxisklinik City Leipzig, Standort Leipzig, Dr med.Astrid Gabert, Dr med. Katharina Bauer, Dr med. Georg SaagerLubeck: UKL-Universitares Kinderwunschzentrum Lubeck, Zentrum furReproduktionsmedizin und Gynakologische Endokrinologie am Univer-sitatsklinikum Schleswig-Holstein, MVZ Ambulanzzentrum des UK-SHGmbH, Prof. Dr med. G. Griesinger, Priv.-Doz. Dr med. A.Schultze-Mosgau, Prof. Dr med. K. Diedrich, LubeckLudwigshafen: Kinderwunschzentrum Ludwigshafen, Dr med. TobiasSchmidt, Dr med. Claudia Schmidt, Dr rer. nat. Nicole Motzkus,LudwigshafenMagdeburg: Kinderwunschzentrum Magdeburg, Dr med. Ingrid Nickel,Dr med. Evelyn Richter, Magdeburg; Universitatsklinik fur Reproduk-tionsmedizin u. Gyn. Endokrinologie, Prof. Dr med. J. Kleinstein, Drmed. A. B. Brossner, Magdeburg

Mannheim: Kinderwunschzentrum Mannheim, Klinikdirektor Prof. Drmed. M. Sutterlin, Dr med. R. Schaffelder, PD Dr med. St. Bussen Drmed. J. Schuttler, Dr Gentili, MannheimMainz: Kinderwunschzentrum der Universitatsmedizin Mainz,Univ.-Prof. Dr Rudolf Seufert M.Sc., Fr. Dr V. Passuello, Univ. Prof. DrH. Kolbl, Mainz; Kinderwunsch Zentrum Mainz, Dr med. Robert Emig,Dr med. Silke Mettlin, MainzMarburg: Universitatsklinikum Gießen—Marburg GmbH, StandortMarburg Klinik fur Gynakologie, gyn. Endokrinologie u. OnkologieSchwerpunkt gyn. Endokrinologie, Reproduktionsmedizin und Osteolo-gie, Prof. Dr med. Peyman Hadji, Prof. Dr med. Uwe Wagner, Dr med.Volker Ziller, MarburgMinden: Zentrum fur Kinderwunschbehandlung und PranataldiagnostikMinden, Dr med. Dipl.-Biochem. Onno Buurman, Dr med. MichaelDumschat, Dr med. Ralf Menkhaus, Dr med. Barbara Heidecker, MindenMonchengladbach: Kinderwunschzentrum Monchengladbach, Dr med.Georg Dohmen, Dr med. Thomas Schalk, MonchengladbachMunchen: A.R.T. Bogenhausen, Prof. Dr med. Dieter Berg, Dr med.Bernd Lesoine, Munchen; Gynakologische Endokrinologie undReproduktionsmedizin der Uni Munchen—Innenstadt,Ludwig-Maximilians-Universitat (LMU), Frauenklinik Innenstadt, PD Drmed. M.S. Kupka, Dr rer. nat. P. Papadopoulos, Munchen; Hormon-und Kinderwunsch-Zentrum der LMU Munchen-Großhadern, Leiter:Prof. Dr Christian J. Thaler, Leitende Embryologin: Dr rer. nat. Viktoriavon Schonfeldt, Klinik und Poliklinik der Frauenheilkunde und Geburt-shilfe, Direktor: Prof. Dr med. Klaus Friese, Munchen; HormonZentrum Munchen, Dr med. H. Lacher, Dr med. J. Puchta, Drmed. S. Michna, PD Dr med. H.-U. Pauer, Munchen; KinderwunschCentrum Munchen-Pasing, Dr med. Klaus Fiedler, Dr med. Irene vonHertwig, Dr med. Gottfried Krusmann, Prof. Dr med. habil WolfgangWurfel, Ina Laubert, Dr med. Claudia Santjohanser, Sabine Volker,Osama Meri, Dr med. Jan Krusmann, Munchen; Zentrum fur Reproduk-tionsmedizin Munchen, Dr med. Walter Bollmann, Dr Thomas Bruck-ner, Dr med. Ulrich Noss, MunchenMunster: Kinderwunschzentrum Munster, Dr med. L. Belkien, Drmed. C. Niehoff, Facharzte fur Frauenheilkunde u. Geburtshilfe,Munster; Kinderwunschsprechstunde Uniklinik Munster—IVF-Bereich,OA Dr med. Schuring, Prof. Kiesel, Martina Kreimer, Prof. Kliesch,MunsterNeubrandenburg: Kinderwunschzentrum Neubrandenburg, Prof. Drmed. Roland Sudik, Dr med. Konstanze Kissing-Pahl, NeubrandenburgNeuwied: Kinderwunschzentrum Mittelrhein Koblenz und Neuwied, DrJosef Beran, Dr Birgit Muller, Koblenz und NeuwiedNurnberg: Kinderwunsch- und Frauen-Hormon-Centrum Nurnberg, DrBarbara Munzer-Neuwinger, Dr Joachim Neuwinger, Prof. Dr PeterLicht, NurnbergOffenbach: Kinderwunschzentrum am Busing Park, Dr med. K.Manolopoulos, OffenbachOldenburg: Tagesklinik Oldenburg, Zentrum fur Kinderwunschbehan-dlung, Dr med. Jorg Hennefrund, Dr med. Heike Boppert (vormalsOchs-Ring), Dr med. Michael Heeder, Oldenburg; Team KinderwunschOldenburg, Dr med. Saif Jibril, Dr med. Gerhard Pohlig, Facharzte furFrauenheilkunde und Geburtshilfe, OldenburgOsnabruck: Zentrum fur Kinderwunschbehandlung Osnabruck, IreneCoordes, Dr med. Manfred Schneider, OsnabruckPforzheim: Centrum fur Kinderwunsch Pforzheim, Verena Peuten,Pforzheim

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Prien am Chiemsee: Kinderwunsch Centrum Chiemsee, Dr med. SusannBoehm, Dr med. Matthias Lehnert, Prien am Chiemsee.Recklinghausen: Reprovita, Kinderwunschzentrum Recklinghausen,RecklinghausenRegensburg: Kinderwunschzentrum Regensburg, Prof. Dr med. BerndSeifert, Prof. Dr med. Monika Bals-Pratsch, RegensburgRemscheid: Institut fur Gynakologische Endokrinologie und Reproduk-tionsmedizin Remscheid, Dr med. J. Luckhaus, RemscheidRostock: Praxiszentrum Frauenheilkunde, PD Dr med. H. Muller,A. Busecke, A. Bossow, RostockSaarbrucken: Uberregionale Gemeinschaftspraxis IVF-Saar Saarbrucken-Kaiserslautern, Drs med. M. Thaele, L. Happel, A. Giebel, N. Nassar,M. Otte, Saarbrucken und KaiserslauternStuttgart: Frauenarztpraxis mit Tagesklinik, Reproduktionsmedizin, Prof.Dr. med. Ute Fuchs, Stuttgart; Gynakologie und Reproduktionsmedizin,Dr med. Fred Maleika, Dipl. Biol. Dr rer. nat. Silvia Harrer, Stuttgart;Kinderwunsch-Zentrum-Stuttgart, Praxis Villa Haag, Dr D. B.Mayer-Eichberger, StuttgartTrier: Praxisklinik Trier, Zentrum fur Gynakologische Endokrinologie &Reproduktionsmedizin, Dr med. M. Satari, Prof. Dr med. J.P. HankerWissenschaftspark (WIP), TrierTubingen: KinderwunschPraxis Dres. Gohring, Dr med. Ulrich Gohring,Dr med. Ines Gohring, Tubingen; UFK-Tubingen, IVF-Zentrum, DrBarbara Lawrenz, Dr Eva Neunhoeffer, TubingenUlm: Kinderwunschpraxis Ulm, Praxis Dr Gagsteiger, Ulm; PraxisklinikFrauenstraße Ulm, Kinderwunschzentrum Ulm, Prof. Drmed. K. Sterzik, Dr med. E. Strehler, Ulm; Sektion fur GynakologischeEndokrinologie und Reproduktionsmedizin, Universitat Ulm, DrK. Hancke, Dr B. Seemann, Dr E. Isachenko, Dr B. Rosenbusch, UlmViernheim: Viernheimer Institut fur Fertilitat, PD. Dr med. StefanieVolz-Koster, Dr med. Christina Nell, Dr sc. hum. Brigitte Hauff, Viern-heimWetzlar:KinderwunschzentrumMittelhessen,Drmed.A.Hajimohammad,B. Oels, WetzlarWiesbaden: MVZ Kinderwunschzentrum Wiesbaden, Dres.med. M. Schorsch, Th. Hahn, G. Adasz, K. Schilberz, WiesbadenWurzburg: Universitats-Frauenklinik Wurzburg, Kinderwunschzen-trum, Dr med. Torsten Frambach, Dr med. Thomas Bernar, Wurzburg;Zentrum fur Kinderwunsch, Pranataldiagnostik, Medizinische Genetik,Dr med. R. Mai, Dr med. W. Schmitt, Frau Dr med. L. Mulfinger,Wurzburg

GreeceAthens: Eugonia; ‘Neogenesis’ IVF Centre; Embryoland IVF Centre; IVFand Genetics; Fertility institute; EMBRYO A.R.TCrete: Mediterranean Fertility Centre and Genetics ChaniaIoannia: IVF Unit of OB/GYN, Medical school, Ioannia UniversityThessaloniki: Unit of Human Assisted Reproductive medicine, Papageor-giou General Hospital

HungaryBudapest: Division of Assisted Reproduction, 1st Departement of OB/GYN, Semmelweis University, Faculty of Medicine; Department of OB/GYN, St. John’s Hospital; Devai Institute; Forgacs Institute; CIRIS

Budapest—Center for International Reproductive Institute andSystem; Robert Karoly Private Clinic; Versys Clinic; Kaali InstituteDebrecen: Kaali InstituteGyor: Kaali InstitutePecs: Departement of OB/GYN, Pecs University of MedicineSzeged: Kaali Institute

IcelandReykjavik: ART Medica-IVF Iceland

IrelandClane: Assisted Conception Unit, Clane General Hospital, Clane, CoKildareCork: Cork Fertility Centre, Fernhurst House, College Road, CorkDublin: Human Assisted Reproduction Ireland (HARI), Rotunda Hos-pital, Dublin 1; Merrion Fertility Clinic, National Maternity Hospital,Dublin 2Galway: Galway Fertility Unit, Brooklawn House, GalwayKilkenny: The Kilkenny Clinic, Green Hill, Kilkenny

ItalyAbano Terme: Centro PMA—Casa di Cura Abano Terme.Ancona: Centro PMA—Presidio Ospedaliero ‘G. Salesi’Aosta: Centro PMA Valle d’AostaAppiano Gentile: Le Bettulle Casa di Cura s.r.l.—Unita di ProcreazioneMedico AssistitaArco: Centro Provinciale per la Procreazione Medicalmente Assistita—Ospedale Alto Garda e Ledro; Gynepro srlAvellino: Fisiopatologia della Riproduzione e Sterilita di Coppia—A.O.R.N. San Giuseppe Moscati di Avellino.Bari: Centro Medico ‘San Luca’; Centro PMA—Casa di Cura SantaMaria; U.O. di Fisiopatologia della Riproduzione Umana e Congela-mento Gameti—A.O. Policlinico Consorziale di Bari; Centro di Fisiopa-tologia della Riproduzione Umana e PMA—U.O. Ostetricia eGinecologia—Ospedale ‘Di Venere’ di Carbonara)Barletta: Pro Andros s.r.l.Battipaglia: Centro Embryos s.r.l.Benevento: Centro di Fisiopatologia della Riproduzione Umana—AORN ‘G.Rummo’ di BeneventoBergamo: Centro di Procreazione Medico Assistita ‘Enrico Radici′-U.O.Ostetricia e Ginecologia—A.O. Ospedali Riuniti di BergamoBollate: Centro di Sterilita della Coppia—U.O. Ostetricia e Ginecolo-gia—A.O. ‘G. Salvini’ di Garbagnate—P.O. Caduti BollatesiBologna: SISMER—Soc. Italiana Studio Med. Ripr.; Tecnobios Procrea-zione s.r.l.; Poliambulatorio Privato GYNEPRO; Centro di Infertilita eProcreazione Medicalmente Assistita—A.O. di Bologna—Universitadegli studi di Bologna—Policlinico S.Orsola—MalpighiBolzano: Centro Sterilita—Ospedale diBolzanoBra: Centro PMA—Casa di Cura ‘Citta di Bra’Brescia: Centro di Fecondazione Medicalmente Assistita—U.O. Oste-tricia e Ginecologia—Casa di Cura ‘Istituto Clinico Citta di Brescia’Brindisi: Casa di Cura SALUS, PROBIOS s.r.l. GinecologiaBrunico: Centro di medicina della riproduzione umana e crioconserva-zione gameti—Ospedale di Brunico.

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Cagliari:Centroper laDiagnosi e Curadella sterilita diCoppia—Universitadegli Studi di Cagliari—Ospedale S. Giovanni di Dio di Cagliari; ServizioOstetricia e Ginecologia—Diagnosi Prenatale e Preimpianto—OpedaleRegionale per le Microcitemico di CagliariCampobasso: Centro Procreazione Medico Assistita—OspedaleCardarelliCantu: Centro Fisiopatologia della Riproduzione del P.O. di Cantu—A.O. ‘Sant’Anna’ di ComoCarmagnola: Lisa s.r.l.Caserta: CARAN srl—Medicina e Biologia della Riproduzione; Centro‘Genesis Day-Surgery DTC Societa Consortile s.r.l.’; Fisiopatologiadella Riproduzione—A.O. San Sebastiano di CasertaCastel Volturno: I.D.F. Clinica Pineta GrandeCastelfranco Veneto: ISIDE s.r.l.—Ambulatorio Specialistico per laRiproduzione AssistitaCastelvetrano: Hermes s.r.l. Servizi Sanitari SelinuntiniCatania: A.O. ‘Cannizzaro’—U.O. Ginecologia e Ostetricia—Servizio diPMA; ARNAS Garibaldi S. Luigi ‘Unita di Fertilizzazione in Vitro’—U.O.di Andrologia ed Endocrinologia della Riproduzione—P.O. Garibaldi;Azienda Ospedaliera Universitaria V. Emanuele—FerrarottoS. Bambino—Unita Operativa di Patologia ostetrica del P.O.S. S.Bambino; Casa di Cura Falcidia srl; Centro di Medicina della Riprodu-zione e Infertilita; CRA s.r.l. Centro di Riproduzione Assistita;G.M.R.—Ginecologia e Medicina della RiproduzioneCattolica: Ospedale Cervesi di CattolicaChianciano Terme: CDM Centro Diagnosi Medica s.r.l.; ChiancianoSalute—Centro di Chirurgia AmbulatorialeChieti: Casa di Cura Spatocco—Centro I.E.M.A.—Istituto EuropeoMedicina della Riproduzione AbruzzeseCitta’ Sant’angelo: Casa di Cura Villa Serena del Dott. L. Petruzzi s.r.l.Cittadella: Centro di Fecondazione Medicalmente Assistita di Citta-della—U.O.A. Ostetricia e Ginecologia—Dipartimento Materno Infant-ile—P.O. di Cittadella—ULSS 15 ‘Alta Padovana’Conegliano: Centro Regionale Specializzato di Fisiopatologia della Ripro-duzione—Ospedale Civile di ConeglianoErice: Casa di Cura Sant’Anna Centro di PMAFermo: Casa di Cura Palmatea—Centro satellite SISMERFirenze: Centro di Fisiopatologia della Riproduzione Umana—Universitadegli Studi di Firenze—A.O. Careggi; Centro di Procreazione Assistita‘Demetra’; Florence—Centro di Chirurgia Ambulatoriale ed Infertilita;Futura Diagnostica Medica—Procreazione Medicalmente Assistita s.r.l.Fossano: Centro per la Riproduzione Umana Assistita—Ospedale diFossanoFrattamaggiore: Centro Fecondazione Assistita—P.O. ‘S. Giovanni diDio’—ASL N.3 di Napoli.Frosinone: Centro Medico LifeGenova: Centro di Fisiopatologia della Riproduzione Umana—Dipt.Ostetricia e Ginecologia Padiglione I Ospedale San Martino; Medicinadella Riproduzione——Ospedale Evangelico InternazionaleGioia Tauro: Gatjc—Gioia TauroGiugliano In Campania: Clinic Center HERA—Centro HERA srl.Gragnano: Studio A.G.O.I. del Dott. A. M. IrolloGrosseto: Demetra—Centro Grossetano per la Cura dell’Infertilita’Lamezia Terme: C.I.S. Medicina Della RiproduzioneL’Aquila: Centro di Procreazione Medicalmente Assistita—U.O.S. Dip.FIVET—Ospedale ‘San Salvatore’—L’Aquila

Latina: U.O. Dipartimentale di Andrologia e Fisiopatologia dellaRiproduzione—Ospedale S. Maria GorettiLecce: Casa di Cura ‘Prof Petrucciani’—Centro di Procreazione Medical-mente AssistitaLivorno: Arca Service s.r.l.Lugo: Laboratorio di Fisiopatologia della Riproduzione Umana—P.O. diLugoMaddaloni: IATREION s.r.l.—Medicina PolispecialisticaManerbio: Dipartimento di PMA—U.O. Ostetricia e Ginecologia—A.O. di Desenzano del Garda—P.O. di ManerbioMantova: Centro di Medicina della Riproduzione ed EndocrinologiaGinecologica—U.O. Ostetricia e Ginecologia—A.O. ‘Carlo Poma’Marostica: Salus S.r.l.—Genera MarosticaMazara Del Vallo: Terzo Millenio s.r.l.Merano: EUBIOSMercogliano: Centro di Fisiopatologia della RiproduzioneMessina: Centro Riproduzione Umana—Chirurgia Ambulatoriale—CRU s.r.l.; U.S. Fisiopatologia della Riproduzione Umana—CentroPMA—Azienda Ospedaliera PapardoMilano: Andrologia e Riproduzione Assistita—U.O. Urologia II—A.O.‘San Paolo’ di Milano—P.O. San Paolo; Casa di Cura IGEA—SezioneProcreazione Medico Assistita; Centro di Fecondazione Assisitita—Casa di Cura ‘Citta di Milano s.p.a.’; Centro di Procreazione MedicoAssistita—Istituto Clinico Citta Studi Spa; Centro di Riproduzione Assis-tita—U.O. Ostetricia e Ginecologia—A.O. Luigi Sacco—P.O. LuigiSacco; Centro Scienze della Natalita—I.R.C.C.S. Ospedale San Raffaele;Centro studi e trattamento per disturbi della fertilita—U.O. Ostetricia eGinecologia- A.O. Ospedale Niguarda Ca Granda; ESPA—CentroEndocrinologia, Sterilita e PMA—Ospedale M. Melloni—A.O. Fatebe-nefratelli e Oftalmico—U.O. Ostetricia e Ginecologia; Fondazione Ca’Granda Ospedale Maggiore Policlinico—U.O. Semplice Dipartimentale(UOSD)—Centro Sterilita’; MATRIS—Medici Associati per la Terapia ela Ricerca dell’Infertilita e Sterilita; Servizi Sforza s.r.l.—Medicina dellaRiproduzioneModena: Centro di Medicina della Riproduzione—Dip.to ScienzeMediche e Chirurgiche Materno-Infantili e dell’adulto—Sez. di Ginecolo-gia ed Ostetricia—A.0. Universita di Modena PoliclinicoMolfetta: One Day Surgery di Ginecologia—Ostetricia—InfertilitaMonteriggioni: Centro Servizi Montearioso s.r.l.Montichiari: Centro di Procreazione Assistita—U.O. Ostetricia eGinecologia—A.O. ‘Ospedali Civili’ di Brescia—P.O. di MontichiariMonza: Centro di Medicina della Riproduzione BIOGENESI- IstitutiClinici ZucchiNapoli: Biologia della Riproduzione ‘Crm—Napoli’ presso casa di curaVilla del Sole; Centro di Fecondazione Assistita Villa Bianca; Centro diPMA—Clinica Mediterranea; Centro di Sterilita—Az. Univ. Policlinico—Universita degli Studi di Napoli Federico I; Centro di Sterilita ed Inferti-lita—Ospedale Internazionale Casa di Cura s.r.l.; Centro PMA del Dipar-timento Assistenziale di Ostetricia, Ginecologia e Neonatologia—A.O.U.Policlinico—Seconda Universita degli Studi di Napoli; U.O.S.C. Ostetriciae Ginecologia—A.O.R.N. ‘A. Cardarelli’; U.O.S.D. Medicina della Ripro-duzione—P.O. ‘S. Giovanni Bosco’—ASL NA 1Noventa Vicentina: Centro di Procreazione Medico Assistita—PresidioOspedaliero II-Ospedale di Noventa VicentinaOderzo: Centro per la Procreazione Medicalmente Assistita ‘GianluigiBeltrame′-ospedale di Oderzo, ULSS9 Treviso

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Ortona: Centro di Procreazione Medicalmente Assistita—ASL n8 2 Uni-versita degli studi ‘G. d’Annunzio’ Chieti Pescara—Ospedale Civile‘G. Bernabeo’ di OrtonaPadova: Analisi Mediche Pavanello s.a.s.; Biotech PMA s.a.s. di BrunoGiuliana; Centro di Procreazione Medicalmente Assistita—Universitadi Padova—A.O. di Padova—Clinica Ginecologica e Ostetrica; Diazs.r.l.—Casa di Cura Privata—Centro di PMA ‘GEMMA’Palermo: Casa di Cura Candela Spa; Centro Andros s.r.l.; Centro di Bio-logia della Riproduzione; Centro di Fisipatologia della Riproduzione—U.O. di Ostetricia e Ginecologia—Ospedale Ingrassia Aienda U.S.L.6—Palermo; Centro di PMA Policlinico di Palermo—A.O.U.P.Giaccone—Clinica Ostetrica Ginecologica Universita di Palermo;Genesy s.r.l.; Nuova Casa di Cure Demma—A.M.B.R.A.; ProcreazioniAssistite Demetra; Servizio di Fisiopatologia della Riproduzione Umanadella Casa di Cure Orestano s.r.l.Parma: Centro Incapacita Riproduttiva CIR—Clinica Ostetrica e Gine-cologica—Azienda Ospedaliero-Universitaria di ParmaPavia: Centro di Ricerca per la PMA—IRCCS Policlinico San Matteo—Universita degli Studi di PaviaPerugia: Servizio di Diagnosi e Cura della Riproduzione Umana StrutturaSemplice Dipartimentale della Struttura Complessa di Ostetricia eGinecologia—Azienda Ospedaliera di PerugiaPesaro: Azienda Ospedaliera San Salvatore di PesaroPieve Di Cadore: Ospedale di Pieve di CadorePisa: Casa di Cura Privata San Rossore; Centro di Fisiopatologia dellaRiproduzione e Procreazione Assistita—Universita degli Studi diPisa—Ospedale Santa Chiara—A.O. Pisana; Ponte San Pietro: Centrodi Medicina della Riproduzione BIOGENESI—U.O. Ostetricia eGinecologia—IRCCS Policlinico San PietroPordenone: Struttura Operativa Semplice di Fisiopatologia della Ripro-duzione Umana e Banca del SemePotenza: Azienda Ospedaliera Regionale ‘San Carlo’—Dipartimentodella donna e del bambino—U.O.C. Ostetricia e Ginecologia—Procrea-zione Medicalmente AssistitaPozzuoli: UOSD Fisiopatologia della Riproduzione Umana—Centro diPMA di II livello—P.O.S. Maria delle Grazie—Pozzuoli—ASL NA2 nordQuartu Sant’elena: Casa di Cura Policlinico Citta’ di QuartuRagusa: ‘Clinica del Mediterraneo’—Centro PMA ‘ASTER’Reggio Di Calabria: Biomeeting s.r.l.Reggio Nell’Emilia: Centro per la Diagnosi e la Terapia della Sterilita Invo-lontaria di Coppia ‘P-Bertocchi’-A.O. Arcispedale S. Maria Nuova;Studio Diagnostico Raoul Palmer s.r.l.Rende: LIFE LAB—Studio Medico Specialistico di Riproduzione e Andro-logiaRoma: A.S.I.C.—Associazione per lo Studio dell’Infertilita di Coppia;Alma Res; Ambulatorio Sterilita della ‘Fabia Mater’; Antinori SeverinoCentro RAPRUI—Day Surgery—Ristemo Medica srl; ARTEMISIA;C.I.P.A.—Centro Italiano Procreazione Assistita; Casa di Cura ‘VillaSalaria’—Servizio di Fisiopatologia della Riproduzione; Centro Bioferti-lity; Centro di Scienze della Riproduzione e Natalita ‘Villa Pia’; Centrodi Sterilita—Istituto di Ginecologia—Policlinico A. Gemelli—UniversitaCattolica del Sacro Cuore; Centro Genesis (c/o Clinica Villa Pia); CentroLEDA; Centro Procreazione Medicalmente Assistita—A.O. ‘San FilippoNeri’; Fisiopatologia della Riproduzione Umana—U.O. di Ginecologia eOstetricia—Azienda Ospedaliera S. Camillo—Forlanini; Genera—Clinica Valle Giulia; Grimaldi Medical spa—Centro Studi Fertilita di

Coppia; Grimaldi Studi Medici—Centro Studi di Ginecologia, Fertilita eParto; IRI Centro Ricerche Medicina della Riproduzione; MachiavelliMedical House; Medicina e Biologia della Riproduzione—European Hos-pital; Nuova Villa Claudia—Centro di Procreazione Medicalmente Assis-tita; One Day Medical Center s.r.l. (Ex Biogenesi); Praxi ProVita Centrodi Fertilita; Servizio Fisiopatologia della Riproduzione e Fecondazione—ASL RM A—Centro della Salute della Donna S. Anna; Unita OperativaFisiopatologia Riproduzione e Terapia Infertilita—Ospedale SandroPertini—ASL RM B; UOC OG C03 Infertilita e Fivet—Azienda Policli-nico Umberto I—Universita ‘Sapienza’Rozzano: I.R.C.C.S. Istituto Clinico Humanitas—Dipartimento di Gine-cologia e Medicina della RiproduzioneSalerno: C.M.R. s.r.l.—Centro di Medicina della Riproduzione; FertilitasM.R.D.S. (Medicina della Riproduzione Day Surgery) s.r.l.; GEA Medicinadella Riproduzione del Dott. Mario Cirmeni; Mediterraneo Medicinadella RiproduzioneSassari: Centro per PMA—Clinica Ostetrica e Ginecologica dell’Univer-sita di Sassari—A.O.U. di SassariSelvazzano Dentro: Poliambulatorio Tencarola—Arcella AnalisiMediche Biolab srlSiena: Centro Diagnosi e Cura Sterilita—Universita degli Studi di Siena—U.O. Ostetricia e Ginecologia—Policlinico Le Scotte-P.O. SeneseSondrio: Centro Sterilita della Coppia—U.O. Ostetricia e Ginecologia—A.O. della Valtellina e della Valchiavenna—Ospedale Civile di SondrioSora:CentroS.T.S. s.r.l.—Ambulatorio FisiopatologiadellaRiproduzione—Ginecologia ed EndocrinologiaTaranto: CREA S.R.L. Centro Riproduzione e AndrologiaTorino: C. M. R. Centro di Medicina Riproduttiva e Procreazione Assis-tita; Centro Medicina della Riproduzione—Dipt. Disciplina Ginec. EOstetriche—Univ. Degli Studi di Torino; Centro Clinico San Carlo diFecondazione Assistita e Ginecologia; Centro di Fisiopatologia dellaRiproduzione Ospedale ‘Maria Vittoria’; Ginecologia Endocrinologica—Centro FIVER Torino—Ospedale Sant’Anna; Livet s.r.l.; Promea s.p.aTrecenta: Centro PMA—Presidio Ospedaliero S. Luca—Trecenta—ULSS 18 di RovigoTreviso: Salute e CulturaTrieste: SSD Procreazione Medicalmente Assistita—IRCCS BurloGarofaloUdine: Casa di Cura ‘Citta di Udine’Umbertide: Studio Associato Ostetrico-Ginecologico e Medicina dellaRiproduzione—G.en.e.r.a UmbertideVallo Della Luciana: Centro di PMA—U.O. Ostetricia e Ginecologia—P.O. San Luca di Vallo della LucaniaVarese: Centro di Procreazione Medico Assistita—U.O. Ostetricia eGinecologia—A.O. ‘Ospedale Circolo e Fondazione Macchi’ diVarese—P.O. Filippo del PonteVenezia: ARC STER—Centro Studi per la Terapia della Sterilita dellaCoppia s.r.l.; Centro di Procreazione Medicalmente Assistita P.O.diMestre—U.O. Ostetricia e Ginecologia Azienda U.L.S.S. 12 Venezia;Venice FertilityVerona: Centro Athena; Centro per la Diagnosi e Cura della Sterilita diCoppia- Ospedale Policlinico G.B Rossi Borgo Roma; Studio Medico‘Tethys’Viareggio: Centro di Riproduzione Assistita ‘Ettore Barale’—U.O.C.Ostetricia e Ginecologia—Ospedale Versilia—USL 12 di ViareggioVicenza: Centro Medico Palladio

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Vignola: San Tommaso Day SurgeryVillorba: Centro do Medicina S.p.A

KazakhtstanAlmaty: IVF Almaty Center; National Institute Obstetrics and Gyne-cology; Centre for Human Reproduction ‘Astana Ekolife’

LithuaniaVilnius: Baltic and American Clinic

MacedoniaBitola: Private IVF Center ‘ PLODNOST’Skopje: University Gyn-Ob Clinic, Medical faculty—Skopje; SpecialGyn-Ob Hospital ‘SISTINA’; General Hospital ‘REMEDICA’

MoldovaChisinau: National Center for Reproductive Health and MedicalGenetics

MontenegroPodgorica: LIFE, private clinicPodgorica: ARS MEDICA, private clinicCetinje: Human Reproduction Department, Hospital Danilo I Cetinje,governmental centre for ART

NorwayBergen: Haukeland UniversitetssykehusHaugesund: Haugesund Sykehus HF; Klinikk HauskensPorsgrunn: Sykehuset Telemark HFTromsø: Universtitetssykehus Nord NorgeTrondheim: Medicus; St Olavs HospitalOslo: Aleris; Rikshospitalet; Ulleval Universitetssykehus; Volvat Medicalsenter

PolandBialystok: BOCIAN Centrum Połozniczo-Ginekologiczne; Klinika Roz-rodczosci i Endokrynologii Ginekologicznej; KRIOBANKMałzenskiej; ARTemida Domitrz i Partnerzy.Bydgoszcz: GENESIS NZOZ Centrum MedyczneGdansk: ‘Invicta’ Klinika Leczenia NiepłodnosciGdynia: GAMETAKatowice: ANGELIUS Szpital PROVITA; Zieba Clinic NZOZ;GYNCENTRUMKielce: GAMETAKrakow: ARTVIMED; MACIERZYNSTWO Centrum Medyczne;PARENS Centrum Leczenia NiepłodnosciLodz: GRAVITA Diagnostyka i Leczenie Niepłodnosci; SALVE-MEDICALublin: AB OVO Sp. z o.o. NZOZ Centrum Zdrowia Rodziny; OVUMRozrodczosc i Andrologia Sp. z o.oMyslowice: NOVOMEDICA

Opole: GMW EMBRIO Sp. z o.oPlock: GRAVIDAPolice: Klinika Medycyny Rozrodu i Ginekologii;Poznan: Klinika Niepłodnosci i Endokrynologii Rozrodu; MedARTRzeszow: PARENSRzgow: GAMETA Szpital RzgowSzczecin: VitroLiveWarszawa: INVICTA Klinika Leczenia Niepłodnosci; INVIMED Eur-opejskie Centrum Macierzynstwa; nOvum Przychodnia Lekarska;Osrodek Diagnostyki i Leczenia NiepłodnosciWroclaw: POLMEDIS Klinika Leczenia Niepłodnosci; INVIMED

PortugalBraga: FERTICARECoimbra: FERTICENTRO; Hospitais da Universidade de Coimbra;ClinimerEspinho: COGEFaro: FertimedGuimaraes: Centro Hospitalar do Alto Ave—Hospital N. S. da OliveiraLisboa: Ava Clinic; British Hospital; CEMEARE; CLINDIGO; CentroHospitalar Lisboa Norte—Hospital de Santa Maria; CLIFER; Imoclinica;IVI-Lisboa; Maternidade Dr Alfredo da Costa; Hospital dos LusiadasOporto: Centro de Genetica Prof. Alberto Barros; CEIE; CETI; Hospitalde Santo Antonio; Hospital de S. Joao; Maternidade Julio DinisPonta Delgada: Clınica do Bom JesusVila Nova de Gaia: Centro Hospitalar

RussiaAstrakhan: Center for Family Planning and ReproductionBarnaul: Siberian institute of human reproduction and geneticsBelgorod: Regional Clinical Hospital of Saint IoasaphBlagoveshchensk: Clinic ‘AmurMed’Bryansk: Regional Center of a Family Planning and Human ReproductionCheboksary: State-financed organization Presidential Perinatal Centerofthe Ministry of Health and Social Development of the Chuvash RepublicChelabinsk: Verlinsky Research Institute of Reproductive Medicine;DNK Clinic; Center for family planning and reproduction.Ekaterinburg: Center for Treatment of Reproductive Function Disorders‘Partus’; Ural Research Institute of Maternity and Child CareIvanovo: Research Institute of Maternity and Childhood n.a. V.N. Gorod-kovKazan: AVA-PETER Ltd Kazansky department; Private clinic ‘Nuriev’sclinic’Kislovodsk: Clinic ‘Elorma’Khabarovsk: State Common Health Institution ‘Perinatal Center’Khanty-Mansiysk: Establishment of Khanty-Mansiysk autonomousokrug—Yugra Clinical hospital of okrugKrasnodar: The Municipal Health Care Institution ‘The Planned Parent-hood and Reproductive Health Center’Krasnoyarsk: Center for Reproductive Medicine; Medical center of gyne-cologic endocrinology and reproduction ‘Three hearts’Makhachkala: Dagestan Centre of Human ReproductionMoscow: Scientific center for obstetrics Gynecology and Perinatologyn.a. V.I.Kulakov; Perinatal medical center, IVF Department; MedicalCenter of Assisted Reproductive Technologies; Medical Center ‘Lera’;

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MAMA fertility Clinic; ART Clinic ‘Test-Tube Babies’; Medical Center forInfertility Treatment ‘Embrion’; Clinic and hospital ‘Moscvorechye’;Moscow Centre of Andrology and Reproductive Gynecology; InfertilityTreatment Clinic ‘Mother & Child’; Medical Centre ‘ART-EKO’; IVFand Genetics Center ‘FertiMed’; EURO-CLINIC; Medical Center‘ASKON’; Endocrinology Research Center; Gynecology Departmentwith the use of ART of the Central Clinical HospitalNizhny Novgorod: Clinic ‘AIST NN’; Federal Budget Health Care Insti-tution ‘Volga district health center’ of the Federal Medical-BiologicalAgencyNovokuzneck: Clinic ‘Media-Service’; Clinic of Women Health and Re-production ‘MEDICA’; Zonal Perinatal CenterNovosibirsk: Medical Center ‘Avicenna’Omsk: The First Clinical Maternity Hospital of Omsk Oblast; Centre ofReproductive MedicineOrenburg: Center of Family Planning and Reproduction; Clinic‘MaxiMed’Rostov-Don: Center of Human Reproduction and IVFSamara: IDK Medical Company; Clinic of Reproductive Health ‘IVF’;Clinical Center of Cells TechnologiesSaratov: Regional Center for Family Planning and Reproduction; Clinic ofDoctor ParamonovSt. Petersburg: International Center for Reproductive Medicine; Saint-Petersburg State Establishment of Health Protection ‘Maternitywelfare clinic ~44’ of Pushkinskiy District, Reproduction and FamilyPlanning Center; ‘AVA-PETER’ Ltd; Baltic Institute of Human Reproduc-tology; ‘Aimed’ Ltd; Mariinsky Hospital, Assisted Reproductive Technol-ogy Department; Advanced Fertility Clinic; Almazov Federal Heart,Blood and Endocrinology Centre; Euromed-ClinicStavropol: Medical Diagnosis Stavropol Regional CentreSyktyvkar: Komi Republik Perinatal CentreTula: Center of New Medical TechnologyTumen: International Medical Center for Reproduction ‘Mercury’;Medical Center ‘Malysh’.Ufa: Republic Center of Perinatology; ‘ANEKO’ Medical Center ‘Family’Vladikavkaz: Republic Center for Family Planning and ReproductionVladivostok: Medical Center for IVF and Endoscopic Surgery in Gyne-cology ‘Santa Maria’Yakutsk: Republic Hospital N1—National Centre of Medicine, Consult-ation of Human Reproduction

SerbiaBelgrade: Klinika za ginekologiju i akuserstvo Klinicki Centar Srbije;Klinika za ginekologiju i akusertsvo—‘Narodni front’; Specijalna gineko-loska bolnica za lecenje steriliteta ‘Jevremova’; Specijalna ginekoloskabolnica za lecenje steriliteta ‘Beograd’; Specijalna ginekoloska bolnica‘Ivanovic’; Specijalna bolnica za lecenje steriliteta ‘Intermedicus BIS’Medijana: Klinika za ginekologiju i akuserstvo, Klinicki Centar ‘Nis’Novi Sad: Klinika za ginekologiju i akuserstvo, Klinicki centar Vojvodine;Specijalna ginekoloska bolnica ‘Genesis’

SloveniaLjubljana: Univerzitetni klinicni center LjubljanaMaribor: Klinika za ginekologijo in perinatologijo,UKC MariborPostojna: Bolnisnica za ginekologijo in porodnistvo

SpainA Coruna: Maternidad BelenAlava: Hospital de TxagorritxuAlbacete: Hospital General de AlbaceteAlicante: Hospital General de Alicante; Hospital Inernacional Medimar;Centro Ginecologic Manjon; IVI AlicanteAlmeria: Unidad de Reproduccion Hospital Virgen del Mar; Cira Medi-terraneo; Roquetas FIV; Clinica JOFRE-FIV; IVI Almeria; URCH. TorrecardenasAsturias: HUCA Unidad de Reproduccion Hospital Materno InfantilBadajoz: Complejo Hospitalario Infanta Cristina (CERHA)Baleares: Instituto Balear de Fertilidad (IBI); Hospital Universitario SonDureta; Hospital Son Llatzer; Hospital de Manacor; Instituto de FertilidadAna Belen CastelBarcelona: Institut Dexeus; IVI Barcelona; Hospital Clınic de Barcelona;Instituto Pous; Centro MedicoTeknon; Fertilab; Gine-3; ESIMER;FECUNMED; IMARAHospital de Sant Pau; Hospital Vall dHebron; Centro de ReproduccionAsistida Sagrada Familia; Instituto de Ginecologia y Reproduccion de Bar-celona; Consorci Sanitari ParcTauli Sabadell; Hospital Quiron Barcelona;Hospital del Mar; Centre Medic Salus XXICaceres: Clınica Norba; Hospital Ciudad de CoriaCadiz: Clınica Medrano; Clinica SERMAN; FIV Recoletos Cadiz; GrupoMedico de Reproduccion GMER; Unidad de Reproduccion Area Sani-taria Campo de Gibraltar. FIV Recoletos JerezCantabria: Hospital Marques de Valdecilla; CER SantanderCastellon: IVI Castellon; H General de CastellonCiudad Real: Clınica Rubal; FIV Recoletos Ciudad RealCordoba: Clinica BAU; H.U. Reina SofiaGipuzkoa: Clınica El Pilar de San SebastianGirona: GINEXX, Unitat Reproduccio Humana Clınica GironaGran Canaria: H.U. Materno Infantil de Las Palmas de Gran CanariaGranada: Hospital Virgen de las Nieves; Clınica Sanabria; CRH Granada;Margen S.LGuadalajara: FIV Recoletos GuadalajaraHuelva: Fertimed Huelva; Unidad de Reproduccion del H Juan RamonJimenezJaen: Clınica Avicena; Clınica Ciudad de JaenLa Rioja: Clınica Ginecologica Juana Hernandez; Hospital San Pedro;Centro Ginecologico RiojanoMadrid: FIV Center; GINEFIV Madrid; Clınica Tambre; IVI Madrid; U.R.HGarcıa del Real; Hospital Severo Ochoa; Unidad de Reproduccion Hos-pital de Alcorcon; Hospital La Paz; IGMR Dres. Ordas y Palomo; FIVRecoletos Madrid; Instituto Para El Estudio De La Esterilidad; FundacionJimenez Dıaz; Hospital Universitario Madrid-Monteprıncipe; HospitalQuiron Madrid; Hospital Clınico San Carlo; Clınica Ruber Internacional;Hospital G Universitario Gregorio Maranon; Instituto Europeo de Infer-tilidad; Hospital Prıncipe de Asturias; Clınica Procreatec; HospitalRamon y CajalMalaga: Malaga FIV; Centro Gutemberg; Hospital Materno-InfantilCarlos Haya; Clınica FERTIA; Clınica Rincon; CERAM (Centro de Repro-duccion Asistida de Marbella); CEMAR (Centro Malagueno de Repro-duccion Asistida); Consulta Jesus Garcıa; Hospital Costa del SolMurcia: Tahe Fertilidad; Clınica IMAR (I Mediterranea Asociados enReproduccion); Hospital Universitario Virgen de la Arrixaca; IVI MurciaNavarra: Unidad de Reproduccion del Hospital Virgen del Camino

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Ourense: Complexo Hospitalario de OurensePontevedra: Hospital Nuestra Senora de Fatima; Povisa, Centro Hospi-talario Universitario de VigoSevilla: Ginemed; Hospital Universitario Virgen del Rocıo; CIVTE; CAREClınica Ginecologica; Instituto Genesis; IVI Sevilla; Hospital UniversitarioVirgen de ValmeTarragona: EmbriogynToledo: Hospital Virgen de la SaludValencia: Hospital Universitario La Fe; IVI Valencia; HGU de ValenciaUnidad de Reproduccion Humana; Clınica Quiron Valencia; HospitalFrancesc de Borja; Policlınico de Valencia; IMERValladolid: FIV Recoletos; Hospital Clınico Universitario de ValladolidVizcaya: Clınica Ginecologica Bilbao; Clınica Euskalduna; Quiron Bilbao;Hospital de Cruces; Galdakao Usansolo OspitaleaZaragoza: Hospital Miguel Servet; URAM de la Clınica Montpellier

SwedenFalun: IVF unit, Falu HospitalGoteborg: Fertility Center, Carlanderska Hospital; Reproduktionsmedi-cin, Sahlgrenska University Hospital, Goteborgs kvinnoklinikLinkoping: IVF unit, RMC, Linkoping University HospitalMalmo: Curakliniken; Oresundskliniken; RMC, Malmo UniversityHospitalOrebro: IVF unit, Orebro University HospitalStockholm: IVF Stockholm, St Gorans Hospital; IVF unit, KarolinskaUniversity Hospital Huddinge; IVF unit, Sophiahemmet; FertilityCenter StockholmUmea: IVF unit, Norrlands University Hospital, UmeaUppsala: Carl von Linne Kliniken; Reproductive Center, AcademicHospital

SwitzerlandBaden: Kinderwunschzentrum Baden, FrauenklinikBasel: Universitats-Frauenklinik Basel; Kinderwunschzentrum RegioBasel; FertilitasBellinzona: EndomedBern: Kinderwunschzentrum, Universitatsfrauenklinik; IVF-TeamLindenhofspitalBiel: CareGeneve: Centre Prive de PMA, Clinique des Grangettes; Unite de lamedecine de la reproduction et d’endocrinologie, HCUG; CentrePMA Clinique Generale Beaulieu-UNILABSLausanne: Unite de Medecine de la Reproduction et d’Endocrinologiegynecologique CHUV; Centre de PMA—Clinique de la Source; Viollier-Medixy; Centre de procreation medicalement assistee (CPMA)Locarno: Centro Cantonale di FertilitaLuzern: Kinderwunschzentrum Luzern, FrauenklinikNiederuzwil: Institut fur Reproduktionsmedizin und EndokrinologieSchaffhausen: Zentrum fur ReproduktionsmedizinSorengo: IIRM (Istituto Internazionale di medicina della riproduzione)St Gallen: Fachinstitut der Ostschweiz fur Reproduktionsmedizin undGynakologische Endokrinologie (FIORE)Winterthur: Sterilitatszentrum WintherthurZurich: IVF Zurich; Universitatsspital Zurich, Kinderwunsch-Zentrum;GYN-A.R.T. AG

The NetherlandsAmsterdam: Academisch Medisch Centrum; Vrije universiteit MedischCentrumEindhoven: Catharina ZiekenhuisGroningen: Universitair Medisch Centrum GroningenLeiden: Leids Universitair Medisch CentrumLeiderdorp: MCKMaastricht: Universitair Medisch Centrum MaastrichtNijmegen: Universitair Medisch Centrum NijmegenRotterdam: Erasmus Medical CentreTilburg: St. Elisabeth ZiekenhuisUtrecht: Universitair Medisch Centrum UtrechtVoorburg: Reiner de Graaf GroepZwolle: Isala

UkraineChernivtsi: Medical centre of infertility treatmentDnipropetrovs’k: Genesis-Dnepr-IVFDonetsk: Isida-Don-IVF; Ukranian–French medical Centre of HumanReproductive Function; Donetsk Regional Centre for Maternity andChild CareIvano-Frankivs’k: Precarpacian Centre of Reproductive MedicineKharkyv: Ltd Sana-med; Center of Human Reproduction ‘Implant’Kyiv: Clinic of Reproductive Medicine Nadija; Institute of ReproductiveMedicine; Neomed;Lviv: IVF clinic ‘Alternatyva’Odessa: Center for Reproductive Medicine REMEDI; LADA Reproduct-ive Health Clinic; Reproductive Medicine Department, University Clinic,Odessa National Medical UniversitySimferopol: Clinic of Crimean State Medical University; Department forReproductive Medicine ‘Genesis’ Clinic

The UKAberdeen: Aberdeen Fertility CentreAldridge: Midland Fertility ServicesBath: Bath Fertility CentreBelfast: Origin Fertility Care; Regional Fertility Centre, BelfastBirmingham: Birmingham Women’s Hospital; BMI Priory HospitalBrentwood: Brentwood Fertility CentreBrighton and Hove: The Agora Gynaecology and Fertility CentreBristol: Bristol Centre for Reproductive MedicineBurton Upon Trent: Burton Hospitals NHS TrustCambridge: Bourn Hall ClinicCanterbury: BMI The Chaucer HospitalCardiff: IVF Wales; London Women’s Clinic, CardiffCheshunt: Herts and Essex Fertility CentreColchester: Bourn Hall Clinic (Colchester)Coventry: Centre for Reproductive Medicine, CoventryCranbrook: Benenden Fertility Centre (BFC)Darlington: London Women’s Clinic, DarlingtonDorchester: The Winterbourne HospitalDundee: Ninewells HospitalEastbourne: Sussex Downs Fertility CentreEdinburgh: Edinburgh Assisted Conception Unit; IVF Scotland

11

1200

Exeter: Peninsular Centre for Reproductive MedicineGateshead: The Gateshead Fertility UnitGlasgow: Glasgow Nuffield Hospital; Glasgow Royal Infirmary; GlasgowCentre for Reproductive MedicineGreat Missenden: The Chiltern Hospital Fertility Services UnitHartlepool: Assisted Reproduction Unit (ARU), University Hospital ofHartlepoolHull: Hull IVF UnitLeeds: The Leeds Centre for Reproductive MedicineLeicester: Leicester Fertility CentreLiverpool: Hewitt Fertility CentreLlantrisant: Centre for Reproduction and Gynaecology Wales (CRGW)London: Assisted Conception Unit, King’s College Hospital; Assisted Re-production and Gynaecology Centre; Barts and The London Centre forReproductive Medicine; Chelsea and Westminster Hospital; CREATECentre for Reproduction and Advanced Technology; CRM London;Guys Hospital; Homerton Fertility Centre; IVF Hammersmith; LondonFemale and Male Fertility Centre; London Fertility Centre; LondonWomen’s Clinic; Reproductive Genetics Institute; The Bridge Centre;

The Centre for Reproductive and Genetic Health; The Lister FertilityClinic.Manchester: CARE Manchester; Manchester Fertility Services LTD; StMary’s HospitalMiddlesbrough: The James Cook University HospitalNewcastle Upon Tyne: Newcastle Fertility Centre at LifeNorthampton: CARE NorthamptonNottingham: CARE Nottingham; NURTURE.Orpington: BMI Chelsfield Park ACUOxford: Oxford Fertility UnitPlymouth: South West Centre for Reproductive MedicineSalisbury: Salisbury Fertility CentreSheffield: CARE Sheffield; Jessop FertilityShrewsbury: Shropshire and Mid-Wales Fertility CentreSouthampton: Wessex Fertility LimitedSwansea: London Women’s Clinic, SwanseaTunbridge Wells: South East Fertility ClinicWoking: Nuffield Health Woking HospitalWolverhampton: St Jude’s Women’s Hospital

12

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Supplementary Table SI Participants of the EIM Consortium.

Country 2010 2009 2008 2007 2006 Members of the European Union European countries

Albania x x x x

Andorra x

Armenia x

Austria x x x x x x

Azerbaijan x

Belarus x

Belgium x x x x x x x

Bosnia x x x x

Bulgaria x x x x x x

Croatia x x x

Cyprus x x x x x

Czech Republic x x x x x x x

Denmark x x x x x x x

Estonia x x x

Finland x x x x x x x

France x x x x x x x

Georgia x

Germany x x x x x x x

Greece x x x x x x x

Hungary x x x x x x x

Iceland x x x x x x

Ireland x x x x x x

Italy x x x x x x x

Kazakhtstan x x x x

Kosovo x

Latvia x x x x x x

Liechtenstein x

Lithuania x x x x x x x

Luxemburg x x

Macedonia x x x x x x

Malta x x

Moldova x x x x

Monaco x

Montenegro x x x x x x

Norway x x x x x x

Poland x x x x x x x

Portugal x x x x x x x

Romania x x x x x

Russia x x x x x x

San Marino x

Serbia x x x x x x

Slovakia x x

Slovenia x x x x x x x

Spain x x x x x x x

Sweden x x x x x x x

Switzerland x x x x x x

The Netherlands x x x x x x x

Continued

13

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Supplementary Table SI Continued

Country 2010 2009 2008 2007 2006 Members of the European Union European countries

Turkey x x x x

The UK x x x x x x x

Ukraine x x x x x x

Vatican City x

Black shaded, no data received;grey shaded, not a member.

.......................... ....................................................................................................................................

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Supplementary Table SII Size of the IVF clinics reporting to the register in 2010.

Country IVF clinics in thecountry

Size of reporting clinics (cycles per year)

All Reporting <100 % 100–199 % 200–499 % 500–999 % ≥1000 %

Austria 29 29 6 20.7 13 44.8 8 27.6 1 3.4 1 3.4

Belgium 18 18 0 0.0 0 0.0 2 11.1 4 22.2 12 66.7

Bulgaria 21 7 1 14.3 2 28.6 2 28.6 1 14.3 1 14.3

Czech Republic 32 32 4 12.5 0 0.0 8 25.0 13 40.,6 7 21.9

Denmark 20 20 1 5.0 0 0.0 4 20.0 9 45.,0 6 30.0

Finland 18 18 0 0.0 4 22.2 7 38.9 6 33.,3 1 5.6

France 107 104 5 4.8 9 8.7 34 32.7 37 35.6 19 18.3

Germany 124 114 12 10.5 12 10.5 39 34.2 29 25.4 22 19.3

Greece 50 9 0 0.0 4 44.4 3 33.3 2 22.2 0 0.0

Hungary 12 12 1 8.3 0 0.0 5 41.7 5 41.7 1 8.3

Iceland 1 1 0 0.0 0 0.0 0 0.0 1 100.0 0 0.0

Ireland 7 6 0 0.0 1 16.7 1 16.7 3 50.0 1 16.7

Italy 202 202 68 33.7 46 22.8 53 26.2 24 11.9 11 5.4

Kazakhstan 10 3 1 33.3 0 0.0 1 33.3 0 0.0 1 33.3

Lithuania 4 1 0 0.0 1 100.0 0 0.0 0 0.0 0 0.0

Macedonia 4 4 0 0.0 0 0.0 2 50.0 2 50.0 0 0.0

Moldova 2 1 0 0.0 0 0.0 0 0.0 1 100.0 0 0.0

Montenegro 3 3 1 33.3 1 33.3 1 33.3 0 0.0 0 0.0

Norway 11 11 0 0.0 0 0.0 3 27.3 4 36.4 4 36.4

Poland 38 29 10 34.5 2 6.9 10 34.5 6 20.7 1 3.4

Portugal 25 25 6 24.0 4 16.0 12 48.0 3 12.0 0 0.0

Romania 13 10 5 50.0 4 40.0 1 10.0 0 0.,0 0 0.0

Russia 116 72 13 18.1 10 13.9 26 36.1 18 25.0 5 6.9

Serbia 14 10 0 0.0 2 20.0 8 80.0 0 0.0 0 0.0

Slovenia 3 3 0 0.0 0 0.0 0 0.0 1 33.3 2 66.7

Spain 160 103 14 13.6 22 21.4 31 30.1 24 23.3 12 11.7

Sweden 16 16 0 0.0 0 0.0 1 6.3 9 56.3 6 37.5

Switzerland 26 25 5 20.0 2 8.0 13 52.0 3 12.0 2 8.0

The Netherlands 13 13 0 0.0 0 0.0 1 7.7 5 38.5 7 53.8

Ukraine 31 18 3 16.7 4 22.2 6 33.3 3 16.7 2 11.1

The UK 72 72 5 6.9 1 1.4 19 26.4 29 40.3 18 25.0

All 1202 991 161 16.2 144 14.5 301 30.4 243 24.5 142 14.3

14

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Supplementary Table SIII Reporting methods in all countries reporting to the EIM in 2010.

Country Requirements Responsibility Reporting methods

Cycles Deliveries

All reporting

Austria Compulsory National Health Authority Individual Individual

Belgium Compulsory National Health Authority Individual Individual

Czech Republic Compulsory National Health Authority Individual Individual

Denmark Voluntary Medical Organization Summaries Summaries

Finland Compulsory National Health Authority Summaries Summaries

Hungary Compulsory National Health Authority Individual Individual

Iceland Compulsory Medical Organization Summaries Summaries

Italy Compulsory National Health Authority Summaries Summaries

Macedonia Voluntary National Health Authority Summaries Summaries

Montenegro Compulsory Medical Organization Summaries Summaries

Norway Compulsory National Health Authority Summaries Summaries

Portugal Compulsory National Health Authority Summaries Summaries

Slovenia Compulsory National Health Authority Summaries Summaries

Sweden Compulsory Medical Organization Individual Individual

The Netherlands Compulsory National Health Authority Individual Individual

The UK Compulsory National Health Authority Individual Individual

Partially reporting

Bulgaria Voluntary Personal initiative Summaries Summaries

France Compulsory National Health Authority Summaries Summaries

Germany Voluntary Medical Organization Individual Individual

Greece Voluntary National Health Authority Summaries Summaries

Ireland Voluntary Medical Organization Summaries Summaries

Kazakhstan Voluntary Medical Organization Summaries Summaries

Lithuania Voluntary Personal initiative Individual Individual

Moldova Voluntary Medical Organization Summaries Summaries

Poland Voluntary Medical Organization Summaries Summaries

Romania Voluntary Medical Organization Summaries Summaries

Russia Voluntary Medical Organization Summaries Summaries

Serbia Compulsory Medical Organization Summaries Summaries

Spain Voluntary Medical Organization Summaries Summaries

Switzerland Voluntary Medical Organization Individual Individual

Ukraine Voluntary Medical Organization Summaries Summaries

Reporting: individual ¼ individual cycles/pregnancy forms; summaries ¼ annual summaries of activities.

15

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Supplementary Table SIV Countries where all clinics reported to the national register in 2010.

Country Cycles Population Females ofreproductiveage (millions)

Cycles/million

Cycles/millionfemales ofreproductive age

ARTdeliveries

ARTinfants

Nationalbirths

ARTinfants(%)

Austria 6402 8.2 1.6 779 3939 1253 1559 78 742 2.0

Belgium 28 521 10.4 2.0 2736 14 494 4649 5199 129 173 4.0

Czech Republic 20 020 10.2 2.1 1962 9380 117 446

Denmark 15 954 5.5 0.9 2893 17 669 3205 3724 63 487 5.9

Finland 9312 5.3 1.0 1772 9719 1781 1859 61 371 3.0

Hungary 5562 10 2.0 557 2703 90 335

Iceland 824 0.3 0.1 2594 12 656 193 216 4903 4.4

Italy 58 860 60.7 11.9 969 4949 7942 9794 561 944 1.7

Macedonia 1497 2.1 0.5 722 3288 451 611

Montenegro 452 0.7 0.1 678 3183 104 136 7690 1.8

Norway 9007 4.7 0.9 1926 10 089 1885 2098 51 442 4.1

Portugal 7179 10.7 2.2 669 3290 1616 1962 101 381 1.9

Slovenia 4419 2 0.4 2206 17 701 987 1131 22 343 5.1

Sweden 17 628 9.1 1.5 1942 11 990 3809 4025 114 971 3.5

The Netherlands 23 627 16.6 3.2 1426 7394 4584 5015 184 397 2.7

The UK 57 856 62.3 12.3 928 4693 14 188 17 014 791 312 2.2

All 267 120 219 42.7 1221 6258 46 647 54 343 2 380 937

ART cycles refer to IVF, ICSI, FER, ED, IVM, FOR and PGD combined. 798 deliveries after IVM and FOR were excluded from the calculations; totals refer to these countries where datawerereported. Females of reproductive age refer to women between 15 and 45 years old (http://www.census.gov/ipc/www/idb/country.php). For the calculation of the cycles/millionfemales of reproductive age, the original numbers (as found in Table I) are used, not the abbreviated numbers as mentioned in this table.

16

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Supplementary Table SV Pregnancies and deliveries after IVF in 2010.

Country Cycles Aspirations Transfers Clinicalpregnancies

Deliveries Pregnanciesper cycle (%)

Pregnanciesper aspiration (%)

Pregnanciesper transfer (%)

Deliveriesper cycle (%)

Deliveriesper aspiration (%)

Deliveriesper transfer (%)

Austria 1014 952 330 32.5 34.7

Belgium 4526 4052 1213 887 26.8 29.9 19.6 21.9

Bulgaria 680 666 514 199 163 29.3 29.9 38.7 24.0 24.5 31.7

Czech Republic

Denmark 6635 6304 5308 1584 1410 23.9 25.1 29.8 21.3 22.4 26.6

Finland 2632 2516 2202 781 630 29.7 31.0 35.5 23.9 25.0 28.6

France 21 783 18 084 5259 4047 24.1 29.1 18.6 22.4

Germany 9545 8876 2663 1825 27.9 30.0 19.1 20.6

Greece 823 710 657 239 197 29.0 33.7 36.4 23.9 27.7 30.0

Hungary 1217 1211 1171 393 32.3 32.5 33.6

Iceland 279 217 73 60 26.3 33.6 21.6 27.6

Ireland 1856 1483 1346 463 379 24.9 31.2 34.4 20.4 25.6 28.2

Italy 8797 7606 6425 1830 1265 20.8 24.1 28.5 14.4 16.6 19.7

Kazakhstan 1282 1282 1170 447 331 34.9 34.9 38.2 25.8 25.8 28.3

Lithuania 59 57 57 15 25.4 26.3 26.3

Macedonia 323 283 253 125 91 38.7 44.2 49.4 28.2 32.2 36.0

Moldova 284 272 260 104 86 36.6 38.2 40.0 30.3 31.6 33.1

Montenegro 29 27 25 13 13 44.8 48.1 52.0 44.8 48.1 52.0

Norway 3118 2942 2575 863 717 27.7 29.3 33.5 23.0 24.4 27.8

Poland 347 335 313 125 56 36.0 37.3 39.9 16.1 16.7 17.9

Portugal 1736 1571 1406 551 418 31.7 35.1 39.2 24.1 26.6 29.7

Romania 566 506 480 208 36.7 41.1 43.3

Russia 14 239 13 817 12 374 4722 3476 33.2 34.2 38.2 24.4 25.2 28.1

Serbia 419 410 351 129 98 30.8 31.5 36.8 23.4 23.9 27.9

Slovenia 1233 1205 1058 414 337 33.6 34.4 39.1 27.3 28.0 31.9

Spain 3456 2880 2474 974 503 28.2 33.8 39.4 14.6 17.5 20.3

Sweden 5754 5348 4724 1702 1312 29.6 31.8 36.0 22.8 24.5 27.8

Switzerland 799 741 605 159 124 19.9 21.5 26.3 15.5 16.7 20.5

The Netherlands 8750 7895 6925 2247 1683 25.7 28.5 32.4 19.2 21.3 24.3

Ukraine 2382 2328 2198 890 646 37.4 38.2 40.5 27.1 27.7 29.4

The UK 21 431 18 738 16 920 5788 5065 27.0 30.9 34.2 23.6 27.0 29.9

All* 88 847 118 280 103 972 34 503 25 819 28.1 29.2 33.2 21.8 22.4 25.5

The recording of deliveries is incomplete, see Supplementary data, Table SXIII. For Austria, Belgium, France, France, Germany and Iceland no data on initiated cycles available. Data on deliveries not available for Austria, Hungary, Lithuania andRomania. No data available for the Czech Republic.*Total refers to those countries where data were reported.

17

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Supplementary Table SVI Pregnancies and deliveries after ICSI in 2010.

Country Cycles Aspirations Transfers Clinicalpregnancies

Deliveries Pregnanciesper cycle (%)

Pregnancies peraspiration (%)

Pregnancies pertransfer (%)

Deliveriesper cycle (%)

Deliveries peraspiration (%)

Deliveries pertransfer (%)

Austria 4768 4476 1663 34.9 37.2

Belgium 13 131 11 830 3385 2345 25.8 28.6 17.9 19.8

Bulgaria 3993 3960 3210 1140 897 28.5 28.8 35.5 22.5 22.7 27.9

Czech Republic

Denmark 5599 5417 4659 1389 1247 24.8 25.6 29.8 22.3 23.0 26.8

Finland 2229 2147 1921 597 475 26.8 27.8 31.1 21.3 22.1 24.7

France 34 709 32 001 9559 7511 27.5 29.9 21.6 23.5

Germany 35 150 33 904 9708 6692 27.6 28.6 19.0 19.7

Greece 1931 1703 1546 530 405 27.4 31.1 34.3 21.0 23.8 26.2

Hungary 3874 3863 3629 1169 30.2 30.3 32.2

Iceland 223 195 73 62 32.6 37.4 27.7 31.8

Ireland 1320 1173 1079 383 306 29.0 32.7 35.5 23.2 26.1 28.4

Italy 43 864 39 843 34 043 9154 6243 20.9 23.0 26.9 14.2 15.7 18.3

Kazakhstan 348 348 329 113 78 32.5 32.5 34.3 22.4 22.4 23.7

Lithuania 53 53 53 18 34.0 34.0 34.0

Macedonia 1086 1009 929 417 342 38.4 41.3 44.9 31.5 33.9 36.8

Moldova 340 328 315 130 110 38.2 39.6 41.3 32.4 33.5 34.9

Montenegro 417 417 389 118 89 28.3 28.3 30.3 21.3 21.3 22.9

Norway 3439 3314 2842 924 785 26.9 27.9 32.5 22.8 23.7 27.6

Poland 8621 8501 7473 2937 2233 34.1 34.5 39.3 25.9 26.3 29.9

Portugal 4139 3856 3346 1197 929 28.9 31.0 35.8 22.4 24.1 27.8

Romania 357 352 336 172 48.2 48.9 51.2

Russia 13 071 12 508 11 451 4233 2981 32.4 33.8 37.0 22.8 23.8 26.0

Serbia 1065 1050 965 372 289 34.9 35.4 38.5 27.1 27.5 29.9

Slovenia 2371 2310 1973 648 515 27.3 28.1 32.8 21.7 22.3 26.1

Spain 29 047 25 994 22 291 8513 5113 29.3 32.7 38.2 17.6 19.7 22.9

Sweden 5838 5499 4869 1719 1336 29.4 31.3 35.3 22.9 24.3 27.4

Switzerland 4683 4452 3709 1065 818 22.7 23.9 28.7 17.5 18.4 22.1

The Netherlands 8148 7639 6789 2426 1846 29.8 31.8 35.7 22.7 24.2 27.2

Ukraine 2882 2794 2613 1020 850 35.4 36.5 39.0 29.5 30.4 32.5

The UK 23 211 23 160 21 488 7228 6386 31.1 31.2 33.6 27.5 27.6 29.7

All* 171 926 249 671 224 653 72 000 50 883 27.7 28.8 32.0 20.4 21.1 23.5

The recording of deliveries is incomplete, see Supplementary data, Table SXIII. For Austria, Belgium, France, Germany and Iceland no data on initiated cycles available. For the Czech Republic, no data are available. Data on deliveries not available forAustria, Czech Republic, Hungary, Lithuania and Romania.*Total rates refer to those countries where data were reported.

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Supplementary Table SVII Pregnancies and deliveries after FER (IVF and ICSI together) in 2010.

Country Thawings Transfers Clinicalpregnancies

Deliveries Pregnanciesper thawing (%)

Pregnanciesper transfer (%)

Deliveries perthawing (%)

Deliveries pertransfer (%)

Austria 620 604 159 25.6 26.3

Belgium 8815 7138 1617 1094 18.3 22.7 12.4 15.3

Bulgaria 272 243 61 47 22.4 25.1 17.3 19.3

Czech Republic 4303 3963

Denmark 3371 2775 572 493 17.0 20.6 14.6 17.8

Finland 3280 815 588 24.8 17.9

France 21 376 18 750 3432 2477 16.1 18.3 11.6 13.2

Germany 17 876 16 947 3430 2150 19.2 20.2 12.0 12.7

Greece 461 442 129 98 28.0 29.2 21.3 22.2

Hungary 413 93 22.5

Iceland 205 200 60 49 29.3 30.0 23.9 24.5

Ireland 882 680 154 123 17.5 22.6 13.9 18.1

Italy 3758 3441 645 434 17.2 18.7 11.5 12.6

Kazakhstan 289 273 74 51 25.6 27.1 17.6 18.7

Lithuania 19 18 7 36.8 38.9 0.0 0.0

Macedonia 49 46 12 8 24.5 26.1 16.3 17.4

Moldova 0 0 0 0

Montenegro 6 6 2 2 33.3 33.3 33.3 33.3

Norway 2443 2046 486 383 19.9 23.8 15.7 18.7

Poland 3733 3550 866 549 23.2 24.4 14.7 15.5

Portugal 921 777 187 140 20.3 24.1 15.2 18.0

Romania 208 152 51 24.5 33.6

Russia 3760 3499 928 563 24.7 26.5 15.0 16.1

Serbia

Slovenia 760 707 162 130 21.3 22.9 17.1 18.4

Spain 8760 7807 2448 1353 27.9 31.4 15.4 17.3

Sweden 5520 4948 1378 1051 25.0 27.8 19.0 21.2

Switzerland 4058 3668 777 544 19.1 21.2 13.4 14.8

The Netherlands 6729 1531 1055 22.8 15.7

Ukraine 1240 1177 334 251 26.9 28.4 20.2 21.3

The UK 10 476 9782 2297 2021 21.9 23.5 19.3 20.7

All* 104 181 104 061 22 707 15 654 20.3 22.7 14.1 15.8

The recording of deliveries is incomplete, see Supplementary data, Table SXIV. Data on the number of thawings are not available for Finland, Hungary and the Netherlands. For Austria,Hungary, Lithuania, Romania and the Netherlands no data on deliveries available. For the Czech Republic, no data on pregnancies and deliveries are available. For Serbia, no data areavailable.*Total rates refer to those countries where data were reported.

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Supplementary Table SVIII Pregnancies and deliveries after egg donation (ED, fresh and frozen cycles) in 2010.

Country Donation Aspirations,fresh

Aspirations,frozen

Transfers,fresh

Transfers,thawed

Pregnancies,fresh

Pregnancies,thawed

Pregnancies/fresh ET (%)

Pregnancies/thawed ET (%)

Deliveries,fresh 1 frozen

Deliveries/donation (%)

Deliveries/ET (%)

Austria

Belgium 1412 826 495 719 427 202 73 28.1 17.1 166 11.8 14.5

Bulgaria 76 75 1 75 11 37 7 49.3 63.6 35 46.1 40.7

CzechRepublic

2365 2278 2447

Denmark 225 225 184 52 28.3 40 17.8 21.7

Finland 370 365 341 393 111 97 32.6 24.7 159 43.0 21.7

France 684 295 570 262 170 51 29.8 19.5 169 20.3

Germany

Greece 446 242 188 263 172 109 59 41.4 34.3 122 27.4 28.0

Hungary 44 27 35 18 51.4

Iceland 65 52 48 51 16 14 33.3 27.5 22 22.2

Ireland 20 14 13 8 61.5 7 35.0 53.8

Italy

Kazakhstan 229 228 69 200 69 106 18 53.0 26.1 86 37.6 32.0

Lithuania

Macedonia 29 21 8 18 8 10 4 55.6 50.0 10 34.5 38.5

Moldova

Montenegro

Norway

Poland 248 231 12 336 12 144 6 42.9 50.0 114 46.0 32.8

Portugal 282 234 312 150 48.1 113 40.1 36.2

Romania 20 20 20 10 50.0

Russia 2147 1586 505 1549 455 746 154 48.2 33.8 672 31.3 33.5

Serbia

Slovenia 16 8 8 0 8 0 2 25.0 2 12.5 25.0

Spain 8615 6808 4313 7187 4032 3891 1512 54.1 37.5 3425 39.8 30.5

Sweden 171 186 148 64 39 34.4 26.4 84 25.1

Switzerland

TheNetherlands

Ukraine 524 358 166 359 160 172 59 47.9 36.9 198 37.8 38.2

The UK 1562 1530 329 1430 304 552 72 38.6 23.7 549 35.1 31.7

All* 18 630 15 825 6612 16 292 6512 6568 2167 47.4 33.3 5973 35.1 29.4

No data available for Austria, Czech Republic, Germany, Italy, Lithuania, Moldova, Montenegro, Norway, Serbia, Switzerland and the Netherlands.*Total rates refer to those countries where data were reported. The recording of deliveries is incomplete, see Supplementary data, Table SXVI.

20

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SupplementaryTableSIX Initiated cycles, pregnancyanddelivery rates byage distribution (years) of women treated withIVF in 2010.

Country Cycles (%) Pregnancy rates (%) Delivery rates (%)

≤34 35–39 ≥40 ≤34 35–39 ≥40 ≤34 35–39 ≥40

Austria NA NA NA NA NA NA NA NA NA

Belgium NA NA NA NA NA NA NA NA NA

Bulgaria 54.6 35.1 10.3 38.5 19.7 12.9 33.7 14.2 5.7

Czech Republic 51.7 40.0 8.3 35.2 18.2 8.9 14.7 7.0 1.9

Denmark 42.7 33.6 23.7 NA NA NA NA NA NA

Finland 50.9 33.2 15.9 37.1 28.9 16.0 31.8 22.1 9.5

France 48.9 35.2 15.9 NA NA NA NA NA NA

Germany 41.1 38.2 20.7 34.7 27.4 15.4 24.8 17.8 8.5

Greece 35.1 35.4 29.5 39.4 30.3 17.3 32.6 26.1 13.1

Hungary 51.3 34.7 14.1 37.2 30.8 18.1 NA NA NA

Iceland 44.1 35.1 20.8 31.7 27.6 13.8 27.6 22.4 8.6

Ireland 26.7 47.0 26.3 29.2 26.8 16.8 26.2 22.1 11.3

Italy 30.3 40.9 28.8 25.5 23.5 12.1 18.4 16.9 6.6

Kazakhstan 58.4 33.8 7.8 39.3 29.6 25.0 31.5 20.3 7.0

Lithuania 50.9 28.1 21.1 27.6 43.8 0.0 NA NA NA

Macedonia 53.9 28.8 17.3 55.2 23.7 12.5 41.4 18.3 3.6

Moldova 60.6 29.6 9.9 40.7 32.1 25.0 34.3 27.4 14.3

Montenegro 69.0 27.6 3.4 60.0 12.5 0.0 60.0 12.5 0.0

Norway 49.1 39.5 11.4 31.0 26.5 17.2 27.0 21.4 11.3

Poland 63.4 30.3 6.3 40.5 31.4 13.6 16.8 16.2 9.1

Portugal 48.4 40.7 10.9 38.1 28.5 15.8 31.2 19.4 10.0

Romania 55.0 36.1 8.9 49.0 39.5 57.5 NA NA NA

Russia 56.8 31.6 11.6 38.5 32.1 17.0 29.4 22.5 10.5

Serbia 43.0 46.8 10.3 38.3 26.0 20.9 33.3 16.8 11.6

Slovenia 56.0 32.3 11.8 39.7 29.6 15.2 34.1 22.4 9.0

Spain 32.5 47.0 20.5 34.6 29.2 17.8 20.7 15.5 8.3

Sweden 46.6 40.6 12.9 33.9 27.1 22.2 28.2 19.5 13.9

Switzerland 32.3 39.8 27.9 28.3 21.1 8.5 24.0 16.4 4.5

The Netherlands NA NA NA NA NA NA NA NA NA

Ukraine 64.4 27.2 8.4 43.4 29.7 15.9 32.7 19.8 8.0

The UK 38.7 41.3 20.0 33.7 27.3 13.5 30.4 23.7 10.4

All 45.6 37.6 16.7 35.4 26.4 14.7 26.1 18.7 8.8

All: percentage of cycles per age group is computed among all countries giving the distribution. Pregnancy and delivery rates are computed on the countries providing them. For France andIceland cycles refer to aspirations. For Belgium initiated cycles are left empty because cycles without oocyte aspiration are not classifiable into IVF/ICSI.

21

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Supplementary Table SX Initiated cycles, pregnancy and delivery rates by age distribution (years) of women treated withICSI in 2010.

Country Cycles (%) Pregnancy rate (%) Delivery rate (%)

≤34 35–39 ≥40 ≤34 35–39 ≥40 ≤34 35–39 ≥40

Austria NA NA NA NA NA NA NA NA NA

Belgium NA NA NA NA NA NA NA NA NA

Bulgaria 38.3 40.8 20.8 33.5 31.2 14.2 28.6 23.7 8.7

Czech Republic NA NA NA NA NA NA NA NA NA

Denmark 54.9 32.2 12.9 NA NA NA NA NA NA

Finland 55.8 30.8 13.4 32.2 25.5 14.6 27.0 19.6 7.6

France 56.4 32.0 11.5 NA NA NA NA NA NA

Germany 43.7 36.8 19.5 34.9 25.5 15.4 25.4 17.2 8.2

Greece 33.7 37.9 28.4 39.3 27.3 13.5 31.0 21.4 8.4

Hungary 52.9 33.6 13.4 35.0 28.8 14.8 NA NA NA

Iceland 52.9 30.5 16.6 39.8 27.9 16.2 34.7 25.0 8.1

Ireland 37.3 44.6 18.1 35.8 27.8 18.0 29.1 22.2 13.4

Italy 29.4 41.3 29.3 29.1 22.2 10.6 21.2 15.5 5.5

Kazakhstan 69.8 24.4 5.7 33.3 34.1 15.0 23.5 23.5 5.0

Lithuania 58.5 30.2 11.3 41.9 31.3 0.0 NA NA NA

Macedonia 52.0 24.2 23.8 51.9 31.2 16.3 45.1 27.4 5.8

Moldova 60.9 29.4 9.7 42.0 35.0 24.2 35.7 30.0 18.2

Montenegro 40.0 29.7 30.2 45.5 26.6 7.1 37.7 16.1 4.8

Norway 54.2 37.7 8.1 29.5 25.4 16.1 25.9 21.1 10.8

Poland 61.0 29.2 9.7 38.9 31.0 13.2 25.5 19.1 7.6

Portugal 47.1 39.3 13.7 34.4 27.4 14.5 27.5 21.3 8.3

Romania 47.9 40.6 11.5 52.6 45.5 39.0 NA NA NA

Russia 57.5 30.2 12.3 36.9 30.7 19.7 27.2 20.9 10.4

Serbia 50.5 41.9 7.6 34.2 38.8 18.5 29.2 27.4 12.3

Slovenia 54.4 31.8 13.8 34.1 21.2 14.9 28.0 16.2 9.8

Spain 39.8 47.0 13.3 37.6 28.8 17.4 24.1 17.3 8.1

Sweden 51.0 38.3 10.7 35.2 25.7 16.1 28.6 19.1 9.8

Switzerland 37.1 40.9 22.0 30.8 22.1 10.4 25.7 16.6 5.1

The Netherlands NA NA NA NA NA NA NA NA NA

Ukraine 60.0 28.8 11.2 41.4 30.1 17.1 35.3 24.4 11.5

The UK 45.5 39.0 15.5 37.2 29.8 16.8 33.7 26.1 12.9

All 45.2 37.5 17.3 35.2 26.6 14.0 28.5 18.5 7.7

All: percentage of cycles per age group is computed among all countries giving the distribution. Pregnancy and delivery rates are computed on the countries providing them. For France andIceland cycles refer to aspirations. For Belgium initiated cycles are left empty because cycles without oocyte aspiration are not classifiable into IVF/ICSI.

22

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SupplementaryTableSXI Initiated cycles, pregnancyanddelivery rates byage distribution (years) of women treated withFER in 2010.

Country Cycles (%) Pregnancies (%) Deliveries (%)

≤34 35–39 ≥40 ≤34 35–39 ≥40 ≤34 35–39 ≥40

Austria NA NA NA NA NA NA NA NA NA

Belgium 65.5 26.2 8.3 20.0 16.2 12.3 13.8 10.2 8.3

Bulgaria 51.8 36.4 11.8 24.8 16.2 31.3 19.9 13.1 18.8

Czech Republic 47.3 34.4 18.3 26.7 16.7 17.6 10.6 7.0 7.0

Denmark NA NA NA NA NA NA NA NA NA

Finland NA NA NA NA NA NA NA NA NA

France NA NA NA NA NA NA NA NA NA

Germany 46.0 38.1 15.9 19.3 16.3 9.4 13.7 11.7 8.0

Greece 44.7 37.1 18.2 31.6 26.9 21.4 23.8 21.6 14.3

Hungary 59.0 33.2 7.8 23.8 18.8 14.7 NA NA NA

Iceland 56.1 30.7 13.2 34.8 23.8 18.5 27.8 20.6 14.8

Ireland 23.8 57.8 18.4 24.3 15.9 13.6 18.1 13.7 9.3

Italy 39.6 43.5 16.9 19.8 18.0 8.8 14.7 11.1 5.2

Kazakhstan 57.1 26.6 16.2 27.4 21.6 25.4 18.8 17.5 22.0

Lithuania 77.8 22.2 0.0 35.7 50.0 NA NA NA NA

Macedonia 57.1 30.6 12.2 17.9 33.3 33.3 10.7 26.7 16.7

Moldova NA NA NA NA NA NA NA NA NA

Montenegro 66.7 33.3 0.0 50.0 NA NA 50.0 NA NA

Norway 58.7 34.1 7.2 19.4 16.9 15.0 15.8 12.8 10.4

Poland 62.9 29.0 8.1 26.2 19.3 16.4 17.1 11.8 8.0

Portugal 50.2 38.1 11.7 25.4 23.6 19.8 20.5 15.9 14.3

Romania NA NA NA NA NA NA NA NA NA

Russia 63.4 27.4 9.1 26.3 23.5 18.9 16.9 15.4 9.8

Serbia NA NA NA NA NA NA NA NA NA

Slovenia 61.3 30.1 8.6 23.2 19.7 13.8 19.3 15.7 6.2

Spain 42.5 44.5 12.9 31.2 26.8 19.9 18.8 14.4 10.7

Sweden 43.2 44.6 12.2 30.2 24.0 21.8 24.0 18.1 14.0

Switzerland 37.8 42.4 19.8 21.1 18.8 16.0 16.2 13.0 9.0

The Netherlands NA NA NA NA NA NA NA NA NA

Ukraine 68.1 22.4 9.5 30.0 22.9 25.4 23.7 16.2 16.4

The UK 43.4 39.5 17.1 23.9 22.2 16.3 21.5 19.4 13.5

All 49.1 37.1 13.8 23.6 20.0 14.8 21.4 18.0 13.4

All: percentage of cycles per age group is computed among all countries giving the distribution. Pregnancy and delivery rates are computed on the countries providing them.

23

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Supplementary Table SXII Initiated cycles, pregnancy and delivery rates by age distribution (years) of women treatedwith ED in 2010.

Country Cycles (%) Pregnancies (%) Deliveries (%)

≤34 35–39 ≥40 ≤34 35–39 ≥40 ≤34 35–39 ≥40

Austria NA NA NA NA NA NA NA NA NA

Belgium 32.3 25.6 42.1 24.3 24.9 23.2 14.3 17.1 13.0

Bulgaria 14.0 26.7 59.3 75.0 73.9 35.3 66.7 43.5 33.3

Czech Republic 14.5 22.1 63.4 33.6 30.9 30.1 15.5 16.6 15.0

Denmark NA NA NA NA NA NA NA NA NA

Finland 19.4 26.7 54.0 NA NA NA NA NA NA

France NA NA NA NA NA NA NA NA NA

Germany NA NA NA NA NA NA NA NA NA

Greece 8.3 22.3 69.4 50.0 41.2 36.4 36.1 26.8 27.5

Hungary 37.1 28.6 34.3 46.2 60.0 50.0 NA NA NA

Iceland 20.2 24.2 55.6 25.0 41.7 27.3 20.0 25.0 21.8

Ireland 10.0 50.0 40.0 100.0 30.0 37.5 100.0 30.0 25.0

Italy NA NA NA NA NA NA NA NA NA

Kazakhstan 30.5 27.1 42.5 55.6 41.7 42.5 39.5 26.4 31.0

Lithuania NA NA NA NA NA NA NA NA NA

Macedonia 19.2 30.8 50.0 80.0 62.5 38.5 80.0 25.0 30.8

Moldova NA NA NA NA NA NA NA NA NA

Montenegro NA NA NA NA NA NA NA NA NA

Norway NA NA NA NA NA NA NA NA NA

Poland 23.6 32.8 43.7 39.0 47.4 42.1 32.9 34.2 31.6

Portugal 9.3 18.6 72.1 58.6 50.0 46.2 48.3 32.8 35.6

Romania 21.1 42.1 36.8 50.0 100.0 0.0 0.0 0.0 0.0

Russia 23.9 24.1 51.9 36.4 48.6 43.7 28.1 38.4 33.5

Serbia NA NA NA NA NA NA NA NA NA

Slovenia 25.0 37.5 37.5 50.0 33.3 0.0 50.0 33.3 0.0

Spain 9.8 28.0 62.2 49.7 49.3 48.7 30.2 32.0 30.6

Sweden 38.9 50.6 10.5 33.8 28.4 31.4 29.2 22.5 22.9

Switzerland NA NA NA NA NA NA NA NA NA

The Netherlands NA NA NA NA NA NA NA NA NA

Ukraine 10.3 27.9 61.8 64.8 49.3 38.3 53.7 43.2 32.7

The UK 17.0 22.8 60.3 34.4 37.0 36.1 28.2 34.2 31.7

All 14.8 26.5 58.7 40.2 44.4 43.1 26.8 30.3 28.5

All: percentage of cycles per age group is computed among all countries giving the distribution. Pregnancy and delivery rates are computed on the countries providing them.

24

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Supplementary Table SXIII Singleton, twin, and triplet deliveries after IVF and ICSI in 2010.

Country Clinicalpregnancies

Documentedpregnancy loss

Lost tofollow-up

Deliveries all Deliveries withknown multiplicity

Singleton (n) % Twin (n) % Triplet %

Austria 2152 285 614 1253 1253 955 76.2 290 23.1 8 0.6

Belgium 4598 911 455 3232 3232 2866 88.7 359 11.1 7 0.2

Bulgaria 1339 279 0 1060 1060 658 62.1 379 35.8 23 2.2

Czech Republic

Denmark 2973 2657 2657 2242 84.4 405 15.2 10 0.4

Finland 1378 273 0 1105 1105 985 89.1 117 10.6 3 0.3

France 14 818 0 11 558 11 381 9333 82.0 2018 17.7 30 0.3

Germany 12 371 2189 1665 8517 8514 5747 67.5 2432 28.6 335 3.9

Greece 769 136 31 602 556 389 70.0 150 27.0 17 3.1

Hungary 1562

Iceland 146 24 0 122 122 105 86.1 17 13.9 0 0.0

Ireland 846 160 1 685 684 549 80.3 130 19.0 5 0.7

Italy 10 984 2294 1182 7508 7508 5836 77.7 1531 20.4 141 1.9

Kazakhstan 560 117 34 409 401 303 75.6 94 23.4 4 1.0

Lithuania 33

Macedonia 542 87 22 433 433 285 65.8 141 32.6 7 1.6

Moldova 234 38 0 196 196 151 77.0 44 22.4 1 0.5

Montenegro 131 29 0 102 102 70 68.6 32 31.4 0 0.0

Norway 1787 285 0 1502 1502 1331 88.6 167 11.1 4 0.3

Poland 3062 302 471 2289 2289 1854 81.0 426 18.6 9 0.4

Portugal 1748 384 17 1347 1347 1066 79.1 272 20.2 9 0.7

Romania 380 78

Russia 8955 1635 863 6457 5914 4543 76.8 1306 22.1 65 1.1

Serbia 501 387 387 310 80.1 57 14.7 20 5.2

Slovenia 1062 210 0 852 852 724 85.0 128 15.0 0 0.0

Spain 9487 1755 2116 5616 5589 4246 76.0 1320 23.6 23 0.4

Sweden 3421 773 0 2648 2648 2492 94.1 153 5.8 3 0.1

Switzerland 1224 282 0 942 942 755 80.1 183 19.4 4 0.4

The Netherlands 4673 3529 3529 3152 89.3 372 10.5 5 0.1

Ukraine 1910 344 70 1496 1496 1122 75.0 357 23.9 17 1.1

The UK 13 016 1339 226 11 451 11 451 9173 80.1 2240 19.6 38 0.3

All 106 662 14 209 7767 77 955 77 150 61 242 79.4 15 120 19.6 788 1.0

For the Czech Republic, Hungary, Lithuania and Romania no data were available. Multiplicity is not known for all deliveries: France: 177, Germany: 3, Greece: 46, Ireland: 1, Kazakhstan: 8, Russia: 543 and Spain: 27. For Austria, no separate data forfresh cycles are available, FER cycles are also included here.

25

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Supplementary Table SXIV Singleton, twin, triplet and quadruplet deliveries after FER in 2010.

Country Clinicalpregnancies

Documentedpregnancy loss

Lost tofollow-up

Deliveries all Deliveries withknown multiplicity

Singleton (n) % Twin (n) % Triplet %

Austria

Belgium 1617 356 167 1094 1094 963 88.0 129 11.8 2 0.2

Bulgaria 61 14 0 47 47 37 78.7 10 21.3 0 0.0

Czech Republic

Denmark 572 493 493 420 85.2 70 14.2 3 0.6

Finland 815 230 0 588 588 545 92.7 43 7.3 0.0

France 3432 0 2477 2436 2194 90.1 239 9.8 3 0.1

Germany 3264 717 397 2150 2063 1731 83.9 310 15.0 22 1.1

Greece 129 27 4 98 94 58 61.7 34 36.2 2 2.1

Hungary 93

Iceland 60 11 0 49 49 44 89.8 5 10.2 0 0.0

Ireland 154 30 1 123 123 109 88.6 13 10.6 1 0.8

Italy 645 181 30 434 434 356 82.0 75 17.3 3 0.7

Kazakhstan 74 23 0 51 49 41 83.7 8 16.3 0 0.0

Lithuania 7

Macedonia 12 4 0 8 8 7 87.5 1 12.5 0 0.0

Moldova

Montenegro 2 0 0 2 2 2 100.0 0 0.0 0 0.0

Norway 486 103 0 383 383 347 90.6 34 8.9 2 0.5

Poland 866 139 178 549 549 489 89.1 60 10.9 0 0.0

Portugal 187 44 3 140 140 122 87.1 17 12.1 1 0.7

Romania 51 17

Russia 928 234 131 563 555 445 80.2 107 19.3 3 0.5

Serbia

Slovenia 162 32 0 130 130 114 87.7 16 12.3 0 0.0

Spain 2448 620 475 1353 1349 1129 83.7 216 16.0 4 0.3

Sweden 1378 327 0 1051 1051 1000 95.1 49 4.7 2 0.2

Switzerland 777 233 0 544 544 489 89.9 54 9.9 1 0.2

The Netherlands 1531 1055 1055 1006 95.4 49 4.6 0 0.0

Ukraine 334 63 20 251 251 203 80.9 46 18.3 2 0.8

The UK 2297 236 40 2021 2021 1674 82.8 346 17.1 1 0.0

All 22 382 3641 1446 15 654 15 508 13 525 87.2 1931 12.5 52 0.3

For Austria, the Czech Republic, Germany, Hungary, Lithuania, Moldova, Romania and Serbia no data were available. Multiplicity is not known for all deliveries: France: 41, Germany: 87, Greece: 4, Kazakhstan: 2, Russia: 8 and Spain: 4.

26

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Supplementary Table SXV Weeks of gestation at delivery (%), according to multiplicity, in ART (fresh, FER and ED cycles together) 2010.

Country Singleton Twin Triplet

20–27weeks

28–32weeks

33–36weeks

371weeks

Suma NA 20–27weeks

28–32weeks

33–36weeks

371weeks

Suma

NA 20–27weeks

28–32weeks

33–36weeks

371weeks

Suma NA

Austria 0.8 4.2 10.3 84.7 955 0 4.5 25.2 53.1 17.2 290 0 25.0 75.0 0.0 0.0 8 0

Belgium 0.8 1.7 8.1 89.5 4108 40 3.4 8.6 43.0 44.9 532 9 11.1 11.1 77.8 0.0 9 0

Bulgaria

Czech Republic

Denmark

Finland 0.6 0.0 7.4 92.0 1542 6 4.4 0.0 42.5 53.1 161 1 0.0 0.0 100.0 0.0 3 0

France

Germany

Greece 7.3 23.8 30.1 38.8 521 0 0.0 39.2 52.7 8.1 222 0 7.4 18.5 66.7 7.4 27 0

Hungary

Iceland 0.6 0.0 6.5 92.9 170 0 4.3 13.0 34.8 47.8 23 0.0

Ireland

Italy

Kazakhstan 13.1 26.7 26.2 34.0 413 16 14.5 31.6 29.1 24.8 125 0 25.0 37.5 0.0 37.5 9 1

Lithuania

Macedonia 1.4 0.7 15.3 82.7 298 4 3.4 6.8 60.3 29.5 146 0 0.0 71.4 28.6 0.0 7 0

Moldova

Montenegro 1.4 2.8 5.6 90.3 72 0 3.1 6.3 18.8 71.9 32 0

Norway

Poland 3.3 12.0 15.0 69.7 1299 123 4.2 9.3 34.7 51.7 255 19 20.0 40.0 40.0 0.0 5 0

Portugal 0.9 1.3 10.4 87.5 1279 10 4.6 10.8 52.6 32.6 327 2 0.0 0.0 80.0 20.0 10 0

Romania

Russia 1.1 1.7 6.4 90.8 5464 179 2.8 6.6 27.0 63.5 1580 61 11.0 31.5 43.8 13.7 74 1

Serbia 0.0 1.9 4.5 93.5 310 0 7.0 5.3 36.8 50.9 57 0 20.0 30.0 40.0 10.0 20 0

Slovenia 1.1 1.6 8.5 88.7 840 220 7.6 7.6 42.0 42.7 153 22

Spain 0.8 1.6 11.1 86.5 7916 1155 2.4 9.6 44.7 43.3 2433 449 10.0 20.0 60.0 10.0 36 6

Sweden 0.6 0.8 4.2 94.4 3598 19 5.5 4.0 25.4 65.2 206 5 40.0 40.0 20.0 0.0 5 0

Switzerland 0.9 1.0 9.0 89.0 1244 3 3.4 8.9 49.8 37.9 237 2 20.0 80.0 0.0 0 5 0

The Netherlands

Ukraine

The UK 0.7 1.8 6.9 90.6 11 404 17 3.0 10.3 38.9 47.8 2742 2 11.9 35.7 47.6 4.8 42 0

All 1.1 2.4 8.5 88.0 41 433 1792 3.3 10.4 39.9 46.3 9521 580 12.3 31.0 47.2 9.5 260 8

aSum: sum of deliveries with data on term date. Percentages are computed on those deliveries. NA, deliveries with unknown term.

27

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Supplementary Table XVI Complications and fetal reductions in 2010.

Country Cycles OHSS Complications to oocyte retrieval Fetal reduction

All Bleeding Infection Maternal death

Austria 6402

Belgium 28 521 75 186 20 18 1 0

Bulgaria 5030 2 7 7 0 0 41

Czech Republic 20 020 53 9 9 0 0

Denmark 15 954

Finland 9312 65 17 11 6 0

France 79 427 30

Germany 62 571 111 164 309 0 0

Greece 3693 27 7 13 0 0 26

Hungary 5562 10 2 0 0 0 6

Iceland 824 5 1 1 0 0 0

Ireland 4078 13 6 3 3 0 0

Italy 58 860 162 119 111 8 0 0

Kazakhstan 2276 16 4

Lithuania 131 0 0 0 0 0 0

Macedonia 1497 21 26 20

Moldova 624 3 1 1 0 0 7

Montenegro 452 4 2

Norway 9007 63 11 7 4 0 0

Poland 13 325 56 33 29 4 0 0

Portugal 7179 47 5 2 3 0

Romania 1151 14 2 3

Russia 34 026 401 47 44 2 0 48

Serbia 1484 20 4 4 0 0 6

Slovenia 4419 34 1 1 0 0

Spain 58 735 180 55 27 5 1 62

Sweden 17 628 1

Switzerland 9540 22 22 3 0 0 8

The Netherlands 23 627

Ukraine 7085 96 11 11 0 0 38

The UK 57 856 139

All 550 296 1500 708 641 53 2 441

28

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Supplementary Table SXVII Intrauterine insemination with husband semen (IUI-H) in 2010.

Country Cycles Deliveries Deliveries (%) Singleton (%) Twin (%) Triplet (%)

Women ,40 years

Austria

Belgium 10 127 663 6.5 96.4 3.6 0.0

Bulgaria 1906 237 12.4 91.6 8.4 0.0

Czech Republic

Denmark 10 903 1487 13.6 89.7 9.7 0.6

Finland 3816 369 9.7 94.3 4.9 0.8

France

Germany

Greece 397 44 11.1 87.8 12.2 0.0

Hungary

Iceland

Ireland 1503 141 9.4 90.8 9.2 0.0

Italy 25 587 2014 7.9 89.0 9.9 1.0

Kazakhstan 778 63 8.1 100.0 0.0 0.0

Lithuania 145

Macedonia 556 50 9.0 74.0 10.0 2.0

Moldova 96 13 13.5 100.0 0.0 0.0

Montenegro 234 12 5.1 100.0 0.0 0.0

Norway 414 47 11.4 87.2 12.8 0.0

Poland 11 118 855 7.7 93.2 6.8 0.0

Portugal 1918 214 11.2 88.3 11.7 0.0

Romania 974

Russia 5607 727 13.0 90.5 8.4 1.1

Serbia 808

Slovenia 740 65 8.8 80.0 20.0 0.0

Spain 21 204 1635 7.7 88.6 10.9 0.6

Sweden

Switzerland

The Netherlands

Ukraine 1466 180 12.3 96.9 3.1 0.0

The UK 7278

All 107 575 8816 9.0 90.4 8.9 0.6

Women ≥40 years

Austria

Belgium 1120 25 2.2 100.0 0.0 0.0

Bulgaria 203 14 6.9 78.6 21.4 0.0

Czech Republic

Denmark 997 44 4.4 90.9 9.1 0.0

Finland 245 7 2.9 100.0 0.0 0.0

France

Germany

Greece 98 3 3.1 100.0 0.0 0.0

Hungary

Iceland

Ireland 188 8 4.3 100.0 0.0 0.0

Italy 6482 206 3.2 95.1 4.9 0.0

Continued

29

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Supplementary Table SXVII Continued

Country Cycles Deliveries Deliveries (%) Singleton (%) Twin (%) Triplet (%)

Kazakhstan 60 3 5.0

Lithuania 10

Macedonia 42 1 2.4 100.0 0.0 0.0

Moldova 14 1 7.1 100.0 0.0 0.0

Montenegro 22 0 0.0

Norway 21 2 9.5 100.0 0.0 0.0

Poland 772 34 4.4 90.6 9.4 0.0

Portugal 126 5 4.0 100.0 0.0 0.0

Romania 50

Russia 535 64 12.0 98.4 1.6 0.0

Serbia 112

Slovenia 0 0

Spain 883 20 2.3 90.0 10.0 0.0

Sweden

Switzerland

The Netherlands

Ukraine 25 1 4.0 100.0 0.0 0.0

The UK 1016

All 13 021 438 3.7 94.7 5.3 0.0

Percentages of singleton, twin and triplet deliveries are counted on the total number of deliveries with known multiplicity.

30

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Supplementary Table SXVIII Intrauterine insemination with donor semen (IUI-D) in 2010.

Country Cycles Deliveries Deliveries (%) Singleton (%) Twin (%) Triplet (%)

Women ,40 years

Austria

Belgium 5503 537 9.8 96.7 3.1 0.2

Bulgaria 611 128 20.9 74.2 25.8 0.0

Czech Republic

Denmark 7248 1169 16.1 93.5 6.4 0.1

Finland 838 115 13.7 96.5 3.5 0.0

France

Germany

Greece 38 8 21.1 62.5 37.5 0.0

Hungary

Iceland

Ireland 219 47 21.5 95.7 4.3 0.0

Italy

Kazakhstan 87 16 18.4 100.0 0.0 0.0

Lithuania

Macedonia 40 5 12.5 80.0 20.0 0.0

Moldova 66 20 30.3 100.0 0.0 0.0

Montenegro

Norway 382 72 18.8 91.7 8.3 0.0

Poland 1749 255 14.6 92.7 7.3 0.0

Portugal 157 25 15.9 88.0 12.0 0.0

Romania 80

Russia C.I.S. 1925 371 19.3 91.6 8.4 0.0

Serbia

Slovenia 5 1 20.0 100.0 0.0 0.0

Spain 5385 710 13.2 87.2 12.1 0.7

Sweden 581 99 17.0 94.9 4.0 1.0

Switzerland

The Netherlands

Ukraine 609 88 14.4 92.0 8.0 0.0

The UK 3012 465 15.4 93.3 6.7 0.0

All 58 635 4131 14.5 91.9 7.9 0.2

Women ≥40 years

Austria

Belgium 715 27 3.8 100.0 0.0 0.0

Bulgaria 72 4 5.6 100.0 0.0 0.0

Czech Republic

Denmark 2305 139 6.0 97.8 2.2 0.0

Finland 117 9 7.7 100.0 0.0 0.0

France

Germany

Greece 27 2 7.4 100.0 0.0 0.0

Hungary

Iceland

Ireland 56 7 12.5 100.0 0.0 0.0

Italy

Continued

31

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Supplementary Table SXVIII Continued

Country Cycles Deliveries Deliveries (%) Singleton (%) Twin (%) Triplet (%)

Kazakhstan 7 1 14.3

Lithuania

Macedonia 13 1 7.7 100.0 0.0 0.0

Moldova 7 1 14.3 100.0 0.0 0.0

Montenegro

Norway 15 1 6.7 100.0 0.0 0.0

Poland 169 15 8.9 78.6 21.4 0.0

Portugal 4 0 0.0

Romania 40

Russia C.I.S. 473 97 20.5 96.9 3.1 0.0

Serbia

Slovenia 2 0 0.0

Spain 732 52 7.1 94.2 5.8 0.0

Sweden 4 1 25.0 100.0 0.0 0.0

Switzerland

The Netherlands

Ukraine 13 0 0.0

The UK 794 41 5.2 92.7 7.3 0.0

All 5565 398 7.2 95.2 3.8 0.0

Percentages of singleton, twin and triplet deliveries are counted on the total number of deliveries with known multiplicity.

32

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Supplementary Table SXIX The sum of fresh and FER (‘cumulative’) delivery rates in 2010.

Country Cycles Deliveries Multipledeliveries

Thawings Deliveries Multipledeliveries

Deliveries Deliveries Multipledeliveries

IVFandICSI

Freshcycles

Freshcycles

FER FER FER Fresh cyclesper initiatedcycle (%)

Fresh andFER perinitiatedcycle (%)

Fresh andFER pertotaldelivery (%)

Austria 6161 1253 298 620 20.3 20.3 23.8

Belgium 20 572 3232 366 8815 1094 131 15.7 21.0 11.5

Bulgaria 4673 1060 402 272 47 10 22.7 23.7 37.2

Czech Republic 12 864 4303

Denmark 12 234 2657 415 3371 493 73 21.7 25.7 15.5

Finland 4861 1105 120 588 43 22.7 34.8 9.6

France 56 492 11 558 2048 21 376 2477 242 20.5 24.8 16.3

Germany 51 720 8517 2767 17 876 2150 332 16.5 20.6 29.1

Greece 2754 602 167 461 98 36 21.9 25.4 29.0

Hungary 5091

Iceland 502 122 17 205 49 5 24.3 34.1 12.9

Ireland 3176 685 135 882 123 14 21.6 25.4 18.4

Italy 52 661 7508 1672 3758 434 78 14.3 15.1 22.0

Kazakhstan 1630 409 98 289 51 8 25.1 28.2 23.0

Lithuania 112 19

Macedonia 1409 433 148 49 8 1 30.7 31.3 33.8

Moldova 624 196 45 0 0 31.4 31.4 23.0

Montenegro 446 102 32 6 2 0 22.9 23.3 30.8

Norway 6557 1502 171 2443 383 36 22.9 28.7 11.0

Poland 8968 2289 435 3733 549 60 25.5 31.6 17.4

Portugal 5875 1347 281 921 140 18 22.9 25.3 20.1

Romania 923 208

Russia 27 310 6457 1371 3760 563 110 23.6 25.7 21.1

Serbia 1484 387 77 26.1 26.1 19.9

Slovenia 3604 852 128 760 130 16 23.6 27.2 14.7

Spain 32 503 5616 1343 8760 1353 220 17.3 21.4 22.4

Sweden 11 592 2648 156 5520 1051 51 22.8 31.9 5.6

Switzerland 5482 942 187 4058 544 55 17.2 27.1 16.3

The Netherlands 16 898 3529 377 49 20.9 20.9 12.1

Ukraine 5264 1496 374 1240 251 48 28.4 33.2 24.2

The UK 44 642 11 451 2278 10 476 2021 347 25.7 30.2 19.5

All 409 084 77 955 15 908 104 181 14 599 1983 20.0 23.7 19.3

For France the numbers are not initiated cycles, but aspirations.

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