Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag...

65
Anhang Tabellen Al - All Erläuterung zu den Tabellen A 2-A 10: MEAN: Mittelwert STD EV: Standardabweichung MIN: Minimum MAX: Maximum VALIDN: Zahl der ausgewerteten Fälle

Transcript of Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag...

Page 1: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

Anhang

Tabellen Al - All

Erläuterung zu den Tabellen A 2-A 10:

MEAN: Mittelwert STD EV: Standardabweichung MIN: Minimum MAX: Maximum VALIDN: Zahl der ausgewerteten Fälle

Page 2: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

Tab

elle

A 1

. P

erio

pera

tive

Let

alit

ät i

nner

halb

der

3 N

arko

segr

uppe

n

Nar

kose

verf

ahre

n P

at.

Nr.

A

lter

u.

Ges

chle

cht

Hal

otha

n 1/

27

G.K

d

731.

1/91

P

.G.

d 76

J.

1/89

I.

E.

<;1

82 J

.

NL

A

2/10

P

.K d

71

J.

Ana

mne

seda

ten

un

d D

iagn

ose

Bel

astu

ngsd

yspn

oe,

chro

nisc

h ob

stru

ktiv

e V

enti

lati

onss

tö­

rung

, 3

Her

zinf

arkt

e.

Infr

aren

ales

Aor

tena

neur

ysm

a

Adi

posi

tas,

Alk

ohol

abus

us,

verg

röße

rte

Leb

er,

erhö

hte

Le­

bere

nzym

e, Z

usta

nd n

ach

Her

zinf

arkt

. In

frar

enal

es A

orte

nane

urys

ma.

Hyp

erto

nus,

Dia

bete

s, D

epre

s­si

on,

Nie

rena

rter

iens

teno

sen

beid

erse

its,

chr

on.

Nie

reni

nsuf

­fi

zien

z.

Chr

onis

che

arte

riel

le V

er­

schl

ußkr

ankh

eit

Sta

dium

11.

Lin

kshe

rzhy

pert

roph

ie,

Hyp

er­

tonu

s.

Chr

onis

ch a

rter

iel1

e V

ersc

hluß

­kr

ankh

eit

Sta

dium

11.

Art

des

Ein

grif

fs

Aor

toil

iaka

ler

Byp

ass

Aor

teni

nter

pona

t

Aor

tobi

fem

oral

er

Byp

ass,

Nie

rena

rte­

rien

plas

tik

bei d

er­

seit

s

Aor

tobi

fem

oral

er

Byp

ass

Pos

tope

rati

ver

Ver

lauf

3. p

osto

p. T

ag a

kute

s A

bdo­

men

, pa

raly

tisc

her

Ileu

s, I

sch­

ämie

synd

rom

rec

htes

Bei

n.

4. p

osto

p. T

ag R

evis

ion,

ora

le

Dek

ompr

essi

on u

nd

Thr

omb­

ekto

mie

, P

neum

onie

, N

iere

n­ve

rsag

en,

Sep

sis.

Unm

itte

lbar

pos

top.

Isc

häm

ie­

synd

rom

bei

der

Bei

ne.

Rev

isio

n, E

mbo

lekt

omie

, S

ep­

sis,

Ver

brau

chsk

oagu

lopa

thie

, M

agen

blut

ung,

Bro

ncho

pneu

­m

onie

, A

nuri

e, D

ialy

se.

Anu

rie

bei

Thr

ombo

sier

ung

der

rech

ten

Nie

rena

rter

ie,

Dia

­ly

se,

hype

rten

sive

Kri

sen.

6.

pos

top.

Tag

Rev

isio

n un

d E

rsat

z d

er r

echt

en A

. re

naH

s du

rch

Pro

thes

e.

7. p

osto

p. T

ag N

ephr

ekto

mie

re

chts

weg

en M

akro

häm

atur

ie.

Intr

aop.

Ver

letz

ung

V.

cava

in­

feri

or,

Sep

sis.

1. p

osto

p. T

ag R

evis

ion

weg

en

Nac

hblu

tung

ret

rope

rito

neal

. 3.

pos

top.

Tag

Thr

ombe

ktom

ie

un

d P

rofu

ndap

last

ik.

4. p

osto

p. T

ag R

evis

ion

weg

en

Blu

tung

ret

rope

rito

neal

. W

egen

Wei

terb

este

hen

des

Isch

ämie

synd

rom

s in

bei

den

Unt

ersc

henk

eln

US

-Am

puta

­ti

on r

echt

s, k

ardi

opul

mon

ale

Insu

ffiz

ienz

, N

iere

nver

sage

n.

Tod

esur

sach

e u

nd

Sek

tion

sbe­

fund

Her

zkre

isla

ufve

rsag

en b

ei S

ep­

sis

un

d N

iere

nins

uffi

zien

z.

9. p

osto

p. T

ag t

o S

ekti

on

Per

iphe

res

Kre

isla

ufve

rsag

en

bei

diff

user

Mag

enbl

utun

g u

nd

se

ptis

chem

Sch

ock.

L

eber

verf

ettu

ng,

alte

r H

erzi

n­fa

rkt,

Tri

kusp

idaH

nsuf

flZ

ienz

, L

unge

nöde

m.

9. p

osto

p. T

ag t

Her

z-K

reis

lauf

-Ver

sage

n be

i S

epsi

s u

nd

Nie

renv

ersa

gen.

20

. po

stop

. T

ag t

o S

ekti

on

Ver

schl

uß d

er P

roth

ese

durc

h al

te T

hrom

ben,

ret

rope

rito

­ne

ale

Blu

tung

en,

Per

iton

itis

, N

iere

n-,

Mil

z-u

nd

Leb

erin

­fa

rkte

, D

arm

nekr

osen

, ak

ute

Pan

krea

titi

s, P

erip

here

s K

reis

­la

ufve

rsag

en.

14.

post

op.

Tag

t

~ &

\0

......

Page 3: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

Tab

elle

Al.

(F

orts

etzu

ng)

1.0

IV

2/55

Z

usta

nd n

ach

Apo

plex

, ST

-A

orto

bife

mor

aler

3.

pos

top.

Tag

Rev

isio

n w

egen

K

ardi

opul

mon

ale

Insu

ffiz

ienz

W

.Z.

d 75

J.

Str

ecke

nsen

kung

, V

ES,

Hyp

er-

Byp

ass

Nac

hblu

tung

, ze

itwei

se V

olu-

bei

Sep

sis

und

Nie

renv

ersa

gen.

~

tonu

s, c

hron

isch

obs

truk

tive

m

enm

ange

lsch

ock.

Sep

sis

12.

post

op.

Tag

t I

Ven

tila

tion

sstö

rung

. A

RD

S,

akut

es N

iere

nver

sage

n,

Chr

onis

ch a

rter

iell

e V

ersc

hluß

-D

ialy

se,

Her

zins

uffi

zien

z.

kran

khei

t S

tadi

um I

II.

2/31

A

lter

Her

zinf

rakt

, H

yper

tonu

s,

Aor

tobi

fem

oral

er

1. p

osto

p. T

ag R

evis

ion

weg

en

Lun

genö

dem

, P

neum

onie

, L

e-K

.L.

d 73

J.

Dia

bete

s, t

rans

itor

isch

isc

häm

i-B

ypas

s A

nast

omos

enin

suff

izie

nz, z

u-be

rver

fett

ung,

trü

be S

chw

el-

sche

Att

acke

n.

nehm

ende

kar

diop

ulm

onal

e lu

ng b

ei d

er N

iere

n.

Chr

onis

ch a

rter

iell

e V

ersc

hluß

-In

suff

izie

nz,

Nie

renv

ersa

gen,

T

odes

ursa

che

peri

pher

es

kran

khei

t S

tadi

um 1

11.

Dia

lyse

. K

reis

lauf

vers

agen

bei

aku

tem

N

iere

nver

sage

n un

d B

ronc

ho-

pneu

mon

ie.

8. p

osto

p. T

ag t

2/8

7

Fet

tleb

er b

ei c

hron

isch

er H

e-A

orto

bife

mor

aler

B

erei

ts i

ntra

op.

erhö

hte

Blu

t-L

unge

nöde

m,

Ple

urae

rguß

, Le

-S

.L.

97

4J.

pati

tis,

Zus

tand

nac

h C

oli-

Sep

-B

ypas

s un

d P

rofu

n-ve

rlus

te w

egen

ver

meh

rter

Blu

-be

rzir

rhos

e, c

hron

isch

ulz

erös

e si

s in

Zus

amm

enha

ng m

it a

l-da

plas

tik

tung

snei

gung

. K

oliti

s.

lerg

iebe

ding

ter

Agr

anul

ozyt

ose

2. p

osto

p. T

ag R

evis

ion

weg

en

Tod

esur

sach

e pe

riph

eres

2

Mon

ate

präo

pera

tiv,

Hyp

er-

Nac

hblu

tung

, M

assi

vtra

nsfu

-K

reis

lauf

vers

agen

. th

yreo

se,

Thr

ombo

zyto

peni

e.

sion

(15

1), z

uneh

men

de k

ar-

10.

post

op.

Tag

t C

hron

isch

e ar

teri

elle

Ver

-di

opul

mon

ale

Insu

ffiz

ienz

, sc

hluß

kran

khei

t S

tadi

um I

II.

Sep

sis,

Anu

rie,

Dia

lyse

. PD

A Z

usta

nd n

ach

3 H

erzi

nfar

kten

A

orto

bife

mor

aler

1.

pos

top.

Tag

Rev

isio

n w

egen

K

ardi

ogen

er S

choc

k be

i fr

i-3

/18

un

d K

oron

arby

pass

(3f

ach)

, B

ypas

s un

d Sy

m-

Nac

hblu

tung

und

fem

orop

o-s,

chem

Inf

arkt

, H

ämat

om im

R

.B.

d 72

J.

chro

nisc

he N

iere

nins

uffi

zien

z pa

thek

tom

ie

plie

tale

m B

ypas

s li

nks,

Sep

sis,

O

p.-G

ebie

t, s

chw

ere

allg

. A

rte-

bei

Nie

rena

rter

iens

teno

se.

Her

zins

uffi

zien

z.

rios

kler

ose

beso

nder

s N

iere

C

hron

isch

art

erie

lle

Ver

schl

uß-

6. p

osto

p. T

ag f

emor

opop

liet

a-un

d H

irn,

Duo

dena

lulk

us.

kran

khei

t S

tadi

um 1

1.

ler

Byp

ass

rech

ts,

Rev

isio

n w

e-21

Tag

e po

stop

. t

gen

Nac

hblu

tung

, A

nuri

e, D

ia-

lyse

, 20

Tag

e po

stop

. ka

rdia

ler

Rei

nfar

kt,

Her

zver

sage

n.

Page 4: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

Tab

elle

A 1

. (F

orts

etzu

ng)

3/2

5

H.H

. Q

75

J.

3/10

5 B

.G.

d 69

J.

Hem

ipar

ese

links

, H

yper

tonu

s,

stum

me

Nie

re l

inks

, L

euko

zy­

tose

unk

lare

r G

enes

e.

Chr

onis

ch a

rter

ielle

Ver

schl

uß­

kran

khei

t S

tand

III

.

Chr

onis

che

Nie

reni

nsuf

fizi

enz,

S

chru

mpf

nier

e re

chts

, H

yper

­to

nus,

Vig

ilanz

stör

ung

bei

Ver

­da

cht

auf

Hir

natr

ophi

e (im

C

f).

Ged

eckt

per

fori

eren

des

Aor

­te

nane

urys

ma.

Aor

tobi

fem

oral

er

Byp

ass

Aor

toil

iaco

fem

oral

er

Byp

ass

1 St

d. p

osto

p. R

evis

ion,

dif

fuse

B

lutu

ng a

us d

er P

roth

ese,

Pro

­th

esen

wec

hsel

, Z

eich

en d

er

Ver

brau

chsk

oagu

lopa

thie

, V

o­lu

men

man

gels

choc

k, t

hera

pie­

resi

sten

te H

erzi

nsuf

fizi

enz.

A

m O

p.-T

ag R

evis

ion

weg

en

Isch

ämie

synd

rom

des

lin

ken

Bei

nes,

Obe

rsch

enke

lam

puta

­ti

on l

inks

weg

en T

hrom

bosi

e­ru

ng d

es B

ypas

sche

nkel

s.

Pos

top.

kar

diop

ulm

onal

e In

­su

ffiz

ienz

, A

nuri

e, l

abor

chem

. Z

eich

en d

es M

yoka

rdin

fark

tes.

The

rapi

eres

iste

nte

Ger

innu

ngs­

stör

ung,

Her

zkre

isla

ufve

rsag

en,

exit

us i

n ta

bula

. o

Sekt

ion.

Kar

diov

asku

läre

Ins

uffi

zien

z,

bei

sten

osie

rend

er K

oron

arar

­te

rien

skle

rose

, al

te u

nd f

risc

he

Myo

kard

infa

rktn

arbe

n, Z

u­st

and

nach

Mit

ralk

lapp

enen

­do

kard

itis

, L

inks

herz

hype

rtro

­ph

ie,

Rec

htsh

erzd

ilat

atio

n,

Nie

rena

trop

hie

rech

ts,

Nie

ren­

atro

phie

lin

ks.

2. p

osto

p. T

ag t

~ JJ '-0

W

Page 5: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

Tab

elle

A 2

a-I,

Häm

odyn

amis

.che

Ver

ände

rung

en b

is N

arko

seei

nlei

tung

bei

Pat

ient

en m

it P

DA

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a. H

erzf

requ

enz

(min

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P-UN

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Page 6: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

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Page 7: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

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Page 8: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

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Page 9: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

Tab

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Page 10: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A4

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Page 11: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A4

c. S

ysto

lisch

er B

lutd

ruck

(m

mH

g)

-0 ,

0

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AU

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P 8H

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P 24

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MEA

N 1

70

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47

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7

13

3.8

67

12~.100

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5.1

25

1

20

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32

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35

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46

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30

30

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30

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20

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40

39

37

37

39

35

32

34

28

39

36

36

35

34

31

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15

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56

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58

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EV

29

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7

21

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9

20

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2

30

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29

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4

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00

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81

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6

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01

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, IIA

X 2

34

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18

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31

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51

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2

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2'10

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N

31

30

29

32

33

29

29

29

19

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3

32

26

30

28

30

p ••

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n.s

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• •

•• n

.s.

Page 12: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 4

d. D

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olis

cher

Blu

tdru

ck (

rnrn

Hg)

PRA

E O

P N

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AU

T-

V~ABKlE

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BK

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2.A

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73

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0

70

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7

69

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H

63

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7

6;.

41

4

63

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41

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60.11~

56

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0

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1

2.9

48

1

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82

1

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41

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43

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9

8.0

1

00

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11

5.0

9

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00

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88

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7;.

0

86

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3

0

30

3

0

30

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26

26

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p n

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MEA

N

67

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5

57

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3

67

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5

67

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6

67

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9

70

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9

62

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66

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5

67

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1

65

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4

81

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2

62

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6

56

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1

57

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6

59

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6

STD

EV

13

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3

17

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0

16

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3

16

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0

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85

1

2.6

48

1

0.;

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1

2.6

21

1

3.4

94

1

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56

1

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1

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47

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34

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41

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36

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48

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48

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43

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39

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37

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42

.0

52

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40

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39

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40

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44

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MAX

1

07

.0

12

4.0

1

20

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11

5.0

9

1.0

1

11

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86

.0

89

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97

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11

3.0

1

27

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87

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77

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VA

LID

N

40

3

9

37

3

6

39

3

5

31

34

2

8

39

3

6

36

3

5

34

31

p ...

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~ H

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6

6.3

23

5

6.9

67

5

6.9

66

5

9.2

19

6

1.8

48

6

4.4

83

5

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29

5

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45

5

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84

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1

61

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8

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76

9

61

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3

54

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3

62

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7

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10

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4

12

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14

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9

14

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4

14

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9

12

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5

11

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6

13

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8

11

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8

12

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2

11

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4

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12

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1

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~ IH

N

50

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33

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38

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37

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41

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37

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33

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35

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36

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36

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41

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35

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34

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9

1.0

8

0.0

9

0.0

9

2.0

1

10

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86

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87

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91

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31

3

0

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3

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33

2

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2

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31

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30

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0 -

Page 13: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 4

e. Z

entr

alve

näse

r D

ruck

(m

m H

g)

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0 N

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67

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9

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52

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3.30

11

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73

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2.5

06

4

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0

3.6

43

3

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8

3.4

43

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4.4

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30

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30

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26

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P ••

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6

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8

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4

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5

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55

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2

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2

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43

3

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4

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3

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39

3

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Page 14: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A4

f. P

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okap

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rer

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schl

ußdr

uck

(mm

Hg)

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kl~

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le

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2

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4.5

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5

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~

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3

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l

Page 15: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 4

g.

Mit

teld

ruck

in

der

A.

pulm

onal

is (

mm

Hg)

-0 .j::

o.

PRA

E O

P N

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AU

T-

V.A

BK

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N

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KL

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FN

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N

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M

2.A

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10 ::s 0<

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18

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20

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3

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0

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6

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3

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78

5

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4

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35

5

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5

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1

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1

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1

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N

40

39

3

7

36

3

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3

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34

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2

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6

21

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20

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4

19

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4

20

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7

STD

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6

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4.5

18

5

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6

4.8

09

4

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5

5.5

15

4

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0

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0.8

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n.8

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Page 16: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A4

h.

Her

zind

ex (

l.m

in-

l.m

-2)

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E O

P N

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AU

T-

V.A

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N.A

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NO

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2.2

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3

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5

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4.~

4.5

4

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4.1

4

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4.9

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6

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6.S

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V

AL

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3

0

30

3

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26

26

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27

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5

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4

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Page 17: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 4

i. S

chla

gind

ex (

mI-

min

-I

_ m -2

) .....

~

PIIA

E O

P N

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AU

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~ ~A

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Page 18: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 4

j. S

chla

garb

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inde

x de

s li

nken

Ven

trik

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(g. m

· m -2

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56.2~()

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3

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Page 19: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 4

k.

Sys

tem

isch

er p

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here

r G

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tgef

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stan

d (d

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297.28~ j64.44~

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Page 20: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 4

1. S

chla

garb

eits

inde

x de

s li

nken

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trik

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72

4

.23

9

5.4

88

3

.74

9

6.9

05

4

.84

8

3.2

99

2

.37

4

10

.64

2

MIN

1

.4

1.5

1

.2

1.3

1

.1

1.2

1

.2

1.8

1

.5

1.5

1

.5

2.0

1

.4

1.3

2

.8

MAX

7

0.2

3

5.8

1

6.0

1

8.9

1

2.9

8

.2

38

.9

24

.0

30

.9

24

.1

26

.1

24

.6

16

.6

11

.7

61

.1

VA

LIO

N

40

39

36

36

39

34

32

33

28

37

35

35

34

33

3

0

p ••

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.s ..

D.S

. n

.s ..

••

n.s

. n

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A >

1

1.6

98

4

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4

3.7

49

3

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0

3.9

28

3

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1

3.3

16

3

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8

3.4

63

4

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3

8.8

07

5

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3

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fAN

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9

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54

8

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8

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11

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5

2.9

99

2

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9

1.5

21

2

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1.8

68

2

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9

1.4

47

2

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6

4.5

99

9

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2

3.2

79

7

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4

4.9

45

8

.09

8

~ ::s

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1

.8

1.2

1

.0

1.0

.9

.7

1

.2

1.3

1

.1

1.2

2

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2.0

1

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2.6

(J

Q

MAX

5

2.7

1

6.3

1

0.3

6

.5

10

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9.9

1

3.2

8

.2

12

.2

22

.6

46

.0

14

.9

40

.8

28

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46

.8

VA

LID

N

30

28

28

30

32

28

29

28

1

7

32

32

23

29

27

29

p ••

• n

.s.

n.8

. n

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• ••

.....

n.s

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n.s

. 0 1.

0

Page 21: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

Tab

elle

A 5

a-c.

Per

iope

rati

ves

Ver

halt

en v

on D

eter

min

ante

n de

r m

yoka

rdia

len

OrB

ilan

z. M

eßpu

nkte

1-1

6 -0

AS

a. D

ruck

-Fre

quen

z-P

rodu

kt (

mm

Hg

·min

-l)

>

PilA

E

OP

N.E

IN-

HA

UT

-V

.AB

KlE

N

.AB

KL

E

V.O

EF

FN

N

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FF

N 1.A.FE~

2.A

.FE

M

OP-

EN

DE

TO

P 1H

-PO

P

2H-P

OP

8H

-PO

P

24

H-P

OP

::t

::r

N

AR

KO

SF-

LE

ITU

NG

S

CH

NIT

T

AO

RTA

A

ORT

A

AO

RTA

A

ORT

A

OF

HN

O

FFE

N

I>l

ART

Jg

HA

lOT

HA

N

~EAN

14

03

4.6

90

1

42

18

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11

62

0.3

1

08

08

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11

49

2.7

1

11

89

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99

05

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1

08

50

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98

96

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1

10

31

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14

47

7.4

1

40

39

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15

04

9.1

1

47

47

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14

56

1.5

ST

DEV

4

(11

1.3

19

5

00

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2

4S

47

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$

97

2.7

2

44

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84

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0

29

13

.S1

3

47

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25

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3

38

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0

55

17

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4

91

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4

43

31

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4

36

5.9

7

49

81

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~IN

74~8.0

~920.0

57~7.0

49

30

.0

61

75

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65

88

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2.C

l 5

71

2.0

5

40

6.0

4

53

6.0

6

30

0.0

6

94

3.0

7

02

0.0

9

10

2.0

7

82

0.0

~AX

24

40

0.0

2

71

44

.0

21

60

0.0

2

14

20

.0 25~84.0

23

75

0.0

1

60

74

.0

16

73

1.0

1

35

80

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20

14

0.0

2

76

00

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23

69

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2

65

50

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26

66

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V

AL

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2

9

30

3

0

30

2

9

26

2

6

24

22

30

2

8

27

21

2

5

22

p n

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••

n.8

. ••

• •

• n

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n.8

. n

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NlA

MEA

N

13

55

0.0

75

8

87

3.0

8

10

70

8.8

1

24

76

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12

73

4.7

1

14

82

.0

11

74

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1

08

77

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11

82

7.7

1

27

47

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18

54

9.6

1

59

98

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16

54

9.8

1

36

34

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14

64

7.5

ST

DE

V

40

10

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0

29

78

.78

3

09

6.8

2

41

37

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4

13

0.2

6

36

42

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3

82

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6

34

92

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3

88

6.5

4

42

07

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5

33

1.9

4

40

83

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4

24

9.6

5

33

89

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4

06

5.7

9

MIN

6

98

5.0

4

43

7.0

6

88

2.0

6

60

0.0

5

52

0.0

4

88

8.0

4

55

0.0

4

13

6.0

4

42

5.0

7

19

8.0

6

23

2.0

8

07

5.0

8

52

6.0

6

60

0.0

7

50

3.0

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21

65

8.0

1

96

00

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27

84

8.0

2

56

54

.0

20

79

0.0

2

04

24

.0

19

26

0.0

1

82

03

.0

20

j50

.0

24

31

0.0

2

77

27

.0

23

08

4.0

2

75

00

.0

20

80

0.0

2

68

64

.0

VA

LID

N

40

3

8

37

3

7

39

3

5

32

3

4

28

3

9

32

3

4

35

3

4

31

P ••

• ••

n

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n.8

. • •

• •

n.s

.

PDA

MEA

N

12

87

9.9

68

8

94

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0

83

11

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9

11

0.3

1

91

11

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9

98

8.6

9

85

97

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8

57

7.9

3

82

79

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9

54

3.2

1

11

38

8.9

1

36

51

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14

81

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1

38

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14

80

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sm

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3

93

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15

2

69

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6

31

99

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3

45

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34

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01

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7

30

57

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32

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68

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1

46

52

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3

65

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1

42

54

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3

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8

38

77

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M

IN

58

00

.0

47

52

.0

48

23

.0

43

00

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46

50

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56

16

.0

34

45

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46

55

.0

40

02

.0

42

84

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44

10

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79

20

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H1

9.0

8

37

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8

96

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M

AX

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46

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1

56

56

.0

17

75

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1

65

64

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25

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1

63

66

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17

57

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1

96

35

.0

16

69

2.0

1

80

48

.0

26

10

4.0

2

15

25

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26

24

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2

41

80

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23

25

6.0

V

AlI

DN

31

3

0

29

3

2

33

2

9

29

2

9

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32

2

6

30

2

8

30

p ••

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ß.5

. ••

••

••

• n

.9.

Page 22: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 5

b.

Kor

onar

er P

erfu

sion

sdru

ck (

rnrn

Hg)

PRA

E O

P N

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AU

T-

V.A

BK

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ßKtE

V

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M

OP-

EN

DE

IO

P

1H-P

OP

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P 8M

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P

24H

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NA

RK

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UN

G

SCH

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AO

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A

ORT

A

AO

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A

ORT

A

OFF

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IHH

N

ART

HA

lOTH

AN

MfA

N

65

.73

3

58

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7

54

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0

51

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7

52

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3

47

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0

42

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0

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45

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46

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50

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4

15

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13

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14

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5

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1

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93

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IN

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24

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30

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8

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8

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9

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9

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6

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5

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6

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6

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7

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9

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7

4.0

6

9.0

6

9.0

n

.o

VA

LID

N

30

3

0

30

3

0

29

2

6

<'5

24

22

30

29

27

26

25

21

p •

D.S

. D

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••

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D.S

.

NLA

ME

AN

59

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9

45

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9

53

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0

52

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3

55

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4

54

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9

50

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6

54

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8

55

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0

~2.5S5

68

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4

52

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0

47

.74

3

46

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6

51

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3

$lO

H

13

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0

12

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1

13

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3

13

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9

11

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9

12

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1

10

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0

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3

14

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7

10

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4

12

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3

12

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6

11

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4

11

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7

11

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6

M''1

3

8.0

2

6.0

3

4.0

2

3.0

3

1.0

3

8.0

2

6.0

2

7.0

2

3.0

3

4.0

3

7.0

2

9.0

2

8.0

2

7.0

3

2.0

M

AX

98

.0

92

.0

86

.0

78

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80

.0

94

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73

.0

75

.0

84

.0

87

.0

90

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81

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70

.0

85

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90

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VA

LID

N

39

3

8

36

3

4

39

3

5

31

34

28

3

8

34

3

6

35

3

4

31

p ••

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n

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n.s

. • •

• • •

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n.s

.

POA

~

MEA

N 5

9.3

55

4

6.9

00

4

6.4

14

4

9.7

42

5

1.2

12

5

1.0

36

4

4.1

07

4

2.5

17

4

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18

4

3.1

25

5

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81

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80

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00

4

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85

5

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67

::r

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1

1.9

54

1

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1

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83

1

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71

1

4.5

40

1

3.6

37

1

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85

1

3.8

81

1

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28

1

2.5

95

1

3.6

27

1

2.4

78

1

4.1

26

1

4.0

52

1

3.3

30

§

MIN

3

7.0

2

1.0

2

6.0

2

5.0

2

8.0

2

4.0

2

5.0

2

1.0

2

9.0

2

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2

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2

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2

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2

7.0

3

3.0

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/

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8

0.0

6

7.0

7

8.0

7

9.0

8

9.0

7

7.0

7

5.0

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64

.0

68

.0

78

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71

.0

74

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78

.0

80

.0

VA

LIO

N

31

30

2

9

31

33

2

8

28

2

9

17

32

3

2

25

30

2

6

30

....

p ••

• n

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D.S

. •

•••

n.s

. n

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n.s

. .... ....

Page 23: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A5

e. A

rter

iell

er 0

2-G

ehal

t (m

l·d

l-I )

- -N

PRA

E O

P N

.EIN

-H

AU

T-

V.A

BK

LE

N

.AR

KlE

V

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N

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N

1.A

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2.A

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EN

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SCH

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N

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~

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AN

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N

16

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4

15

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3

14

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0

14

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2

14

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2

13

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9

13

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2

14

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4

14

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0

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0

15

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9

15

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3

15

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2

15

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2

H.7

37

0<

>

STD

EV

Z.4

80

2

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4

2.5

22

2

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9

2.25~

1.8

86

1

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5

1.6

81

1

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6

2.0

92

2

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6

1.8

44

1

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5

1.9

17

1

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2

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1

2.7

1

0.3

9

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10

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10

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11

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11

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11

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10

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10

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12

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11

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10

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11

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10

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MAX

2

2.8

2

1.6

1

9.2

1

9.5

1

8_

5

17

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18

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16

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19

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18

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19

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19

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19

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19

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18

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VA

lID

N

29

2

7

28

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27

2

5

25

22

20

28

2

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27

22

22

21

p ••

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fi.

S.

NLA

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N

15

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8

14

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8

14

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5

14

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9

14

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6

13

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8

13

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5

14

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14

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4

14

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3

15

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1

16

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1

15

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7

15

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5

16

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3

STD

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1.9

29

2

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1

1.9

55

2

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6

1.6

21

1

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9

1.2

73

1

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4

1.0

20

1

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8

1.1

93

1

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7

1.6

88

2

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3

1.6

63

M

IN

11

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8.3

9

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11

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10

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9.2

1

0.3

1

2.6

1

2.9

1

0.8

1

3.4

1

4.0

1

2.3

8

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13

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MAX

1

9.3

1

8.3

1

7.9

2

3.6

1

7.8

1

6.1

1

5.9

1

7.1

1

7.2

2

0.8

1

7.2

1

9.2

1

8.3

2

1.5

1

9.9

V

ALI

DN

3

7

36

35

3

3

34

31

2

8

32

2

7

37

3

0

31

31

30

2

3

p ••

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fi.S

. fi.S

. ••

••

n.s

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POA

MEA

N 1

6.5

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Page 24: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

Tab

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Page 25: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 6

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Page 26: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 6

c. A

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nöse

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Page 27: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 6

d. 0

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3

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2

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3

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3

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4

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Page 28: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 6

e. G

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enös

e O

rSät

tigu

ng (0

/0)

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N

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AU

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N

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73

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6

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77 .6

04

7

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25

7

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59

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32

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81

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6

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6

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6

2.8

6

1.5

6

2.8

6

3.5

6

6.9

6

4.8

6

4.4

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6

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5

8.0

5

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5

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6

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1\

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88

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Page 29: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

Tab

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a,b

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s V

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von

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2

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2

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2

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2

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N

29

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8

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~0.3

30

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19

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17

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22

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26

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8

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14

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16

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13

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2

MIN

2

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1

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8.7

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2

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3

0.4

3

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10

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92

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N

28

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Page 30: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 7

b. A

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5

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31

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4

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3.7

3

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3.7

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4.1

3

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3.4

4

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4.3

3

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4.3

3

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4.1

4

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MAX

5

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6.3

5

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5

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6.3

7

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6.6

6

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9

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5.9

6

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6.6

5

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VA

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N

30

2

9

29

2

6

27

2

5

25

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2

2

28

2

7

27

2

6

24

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Page 31: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

Tab

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Page 32: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 8

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Page 33: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 8

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Page 34: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

A 8

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Page 35: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

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Page 36: Anhang - Springer978-3-642-71519-8/1.pdf · Kolitis. lergiebedingter Agranulozytose 2. postop. Tag Revision Todesursache peripheres 2 Monate präoperativ, Hyper-Nachblutung, Massivtransfu-Kreislaufversagen.

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126 Anhang

Tabelle A 9a. Hämodynamische Veränderungen durch Volumengabe und gleichzeitige Periduralanalgesie. Es sind jeweils die Parameter an Meßpunkt 1 und 2 angegeben

Herzfrequenz (min - ')

HK., 1

MF.AN 84.129 STIl EPR 3.379 MEDIAN 84.667 MODE 85.000 8TD DEV 18.814 VARIANCE 3'.";3.981 I<:URTOSIS --0.320 SKEWNESS 0.022 RANGE 72.000 MINIMUM 50.000 MAXIMUM 122.000

HK. 2

MEAN 73.704 STIl ERR 3.194 MEDIAt-! 74.000 MODE 49.000 STD I'EV 16.599 VARI ANCE 275.523 I<:URTOSIS --0.673 SKEWNESS 0.179 RANGE 63.000 MINIMUM 48.000 MAXIMUM 111.000

Arterieller Mitteldruck (mm Hg)

"'Al' 1

MF.AN 97.258 STIl ERR 2.783 MEfITA'" 99.000 MODE 72.000 STD DEV 15.496 \)ART.At4CE 240.131 KURTOSIS 0.054 SKEWNESS 0.364 ~:ANGE 66.000 MINIMUM 72.000 MAXIMUM 1~8.000

"'AP2

MEAM 84.148 STD EF:R 4.059 MErIJAN 83.250 MODE 71.000 STD DEV 21.089 I)ARI ANCE 444.745 KURTOSIS 0.958 SI\EWNESS 0.394 j=;:ANßE 97.000 MINIMUM 44.000 MAXIMUM 141.000

Systolischer Blutdruck (mmHg)

SAP 1

MEAN 152.968 STIl ERR 5.305 MHllA!>! 1'+7.7'50 MODE 133.000 STD DEV 29.::'i37 \)ARIANCE 8-72.430

KURTOSIS 0.464 SI<:EtJNESS 0.529 F:A""3E 134.000 MINIMUM 100.000 MAXIMUM 234.000

SAP,2

MEAN 137.815 STIt ERR 6.750 /o1EIIIPN 140.000 MODE 131.000 STD DEI) 35.076 VARIANCE 1.230.309 KURTocHS 1.675 SKFIJI'!ESS 0.606 RANGE 162.000 MINIMUM 78.000 MAXIMUM 240.000

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Anhang 127

Diastolischer Blutdruck (mm Hg)

UAP'l

MEAN 66.323 STIl ERR 1.910 MFTIIAN 67.000 MOIIE 52.000 STD DEV 10.634 VARIANCE 113.092 KURTOSIS -0.712 SKEWNESS 0.276 RANGE 41.000 MINIMUM 50.000 MAXIMUM 91.000

UAP2

MEAN 62.125 STIl ERR 3.046 MEIIIAN 59.500 MOllE 51.000 STD DEV 14.924 VARIANCE 222.723 KURTOSIS -0.173 SKEWNESS 0.715 RAf\l9E 56.000 MINIMUM 41.000 MAXIMUM 97.000

Zentralvenöser Druck (mm Hg)

CVP1

MEAN 3.677 STI' ERR 0.567 FlEIIIAN 3.250 MODE 0.000 STD DEV 3.156 VARIANCE 9.959 KURTOSIS -0.937 SKEWw.::SS 0.454 RANGE 10.000 MINIMUM 0.000 MAXIMUM 10.000

CVP2

MEAN 4.259 STI' ERR 0.514 MEIIIAN 3.286 HOltE 3.000 STD DEV 2.669 VARIANCE 7.123 KURTOSIS -0.304 SKEWNESS 0.709 Rfl>.NGE 10.000 MINIMUM 0.000 MAXIMUM 10.000

Pulmokapillarer Verschlußdruck (mmHg)

PCW1

MEAN 6.968 STIl ERR 0.731 MElIIAN 6.375 HODE 4.000 STD DEV 4.070 VARIANCE 16.566 KURTOSIS -0.021 SKEWNESS 0.662 RAMGE 16.000 MINIMUM 1.000 MAXIMUM 17.000

PCW2

I'IEAN 8.074 STIl ERR 0.716 MEIIIAN 9.250 MODE 12.000 STD DEV 3.720 VARI ANCE 13.840 KURTOSIS -1.083 SKEWNESS -0.542 RANGE 11.000 MINIMUM 1.000 MAXIMUM 12.000

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128 Anhang

Mitteldruck in der A. pulmonalis (mmHg)

PAPl

MEAN 17.862 STD ERR 1.145 MEIIIAN 16.7'50 MODE 12.000 STD IIEV 6.169 VARIANCE 38.052 KURTQSIS 0.089 SKEIJNESS 0.863 RANGE 23.000 MINIMUM 10.000 MAXIMUM 33.000

PAP2

MEAN 17.296 STIl ERR 0.880 MEIIIAN 17.333 HODE 21.000 STD DEV 4.573 VARIANCE 20.909 KURTOSIS -1.045 SKEIJHESS -0.139 RANGE 16.000 MINIMUM 9.000 MAXIMUM 25.000

Herzindex (1. min -1. m -2)

CIl

MEAN 3."317 STIl ERR 0.143 MEDIAN 3.109 HODE 2.0'59 STD llEV 0.783 VARIAHCE 0.613 KURTOSIS -0.237 SKEIJHESS 0.580 RA"'GE 3.209 MINIMUM 2.059 MAXIMUM 5.268

CI2

MEAN 3.201 STIl ERR 0.127 MEIIIAN 3.012 MODE 2.357 STD DEV 0.659 VARIANCE 0;434 KURTOSIS 0.417 SKEIJNESS 0.925 RANGE 2.630 MINIMUM 2.357 MAXIMUM 4.987

Schlagindex (mI. min -1 . m - 2)

SI1

MEAN 40.931 STIl ERR 1.529 MErIIAN 40.386 MODE 27.339 STD DEI) 8.235 VARIANCE 67.820 KURTOS!S 0.548 SKEIJNESS 0.58'1. F:ANGE 34.833 MINIMUM 27.339 MAXIMUM 62.171

512

HEAN 44.337 STD ERR 1.457 MEJ((AN 43.528 MODE 28.097 STD DEV 7.573 VARIANCE 57.351 KURTOSIS -0.683 5KEIJHF.SS 0.001 F~ANGE 29.061 MINIMUM 28.097 MAXIMUM 57.158

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Schlagarbeitsindex des linken Ventrikels (g·m·m- 2)

LVSl1

MEAH 49.555 STD ERR 2.590 I'1ODE 23.779 STD DEV 14.188 KURTOSIS 0.161 SKEWNESS 0.212 MINIMUM 23.779 MAXIMUH 81.565

LVSI2

MEAH 45.844 STIl ERR 2.730 MODE 23.768 STD DEV 14.186 KUI::TOS!S -0.295 SKEWNESS 0.509 MINIMUM 23.768 MAXj:I'IUM 75.692

Systemischer peripherer Gesamtgefäßwiderstand (dyn·s·cm-s·m-~

SVR1

MEAN 1271.954 STD ERR 53.270 MOllE 788.660 STD IIEV 281.880 KIJF:TOSIS -0.986 SKEWNESS 0.095 MINIMUM 788.660 MAXIMUM 1775.700

SVR'2

MEAH li53.406 STIl ERR 58.361 MODE 594.360 STD DEV 303.255 KURTOSIS -0.840 SKEWNESS -0.066 MINIMUM 594.360 MAX I MUH 1690.140

Druck-Frequenz-Produkt (mmHg·min- 1)

RPf'l

MEAN 12879.965 STIl ERR 706.839 MODE 5800.000 STD DEV 3935.512 KURTOSIS 0.313 SKEWNESS 0.712 MINIMUM 5800.000 MAXIMUM 22464.000

RPP2

MEAH 10296.703 STD ERR 789.306 MODE 4524.000 STD DEV 4101.355 KUIHOSIS 2.847 SKEWNESS 1.313 MINIMUM 4524.000 MAXIMUM 23280.000

Anhang 129

MEIIIAN 51.155 VARIANCE 201.295 RANGE 57.786

MEIIIAM 42.637 VARI ANCE 201.235 PANGE 5t.924

MEIIIAN 1207.655 VARIANCE 79456.437 RANGE 987.040

MEIIIAN 1205.120 VARtANCE 91963.500 RANGE 1095.700

MEIIIAN 12495.000 VARIANCE*488256.000 RANCt 16664.000

MEIIIAM 9694.000 VARIANCE*821136.000 RANGE 18756.000

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130 Anhang

Koronarer Perfusionsdruck (mmHg)

CPP1

MFA'" 59 .. 355 STI' ERP MODE 70.000 STD DEV KURTOSIS -1.057 SKEWNESS MINIMUM 37.000 MAXIMUM

CPP2

MFAN 51..769 STIl ERR MODE 39.000 STD l'EV KURTOSIS 0.092 SKFWNFSS MINIMUM 28.000 MAXIMUM

2.147 11.954 -0.165 80.000

2.928 14.930 0.634

88.000

MF.II I AI-! VARIt-+lCE RAI-!GE

ME:IIIAN VARIANCE ~:ANGE

58.250 142.903 43.000

49.167 222.904

60.000

Tabelle A 9b. Veränderungen der Oz-Transportvariablen durch Volumengabe und gleichzeitige Periduralanalgesie. Es sind jeweils die Parameter an Meßpunkt 1 und 2 angegeben

02-Angebot (ml·min-l.m-~

D02 1

MEAN MODE KURTIJSIS MINIMUM

002 2

MEAN MODE !';UF:TOSIS MINIMUM

530.904 313.406 -1.022

313.406

460.080 259.239

0.216 259.239

02-Verbrauch (ml·min- 1 .m-2)

VU2l

MEAN 118.867 MODE 76.593 KURTOSIS 0.062 MINIMUM 76.593

VUi 2

MEAN 109.472 MODE 62.566 KURTOSIS 0.691 MINIMUM 62.566 ..

STD EF:R STD DEV SKEWNESS MAXIMUM

STIl ERR STD DEV SKEWNESS MAXIMUM

STD ERR STIl DEV SKE\,JNESS MAXIMUM

STD ERR STD DEV SKEWNESS MAXIMUM

22.801 116.2b2

0.197 727.514

18.630 93.152

0.261 658.898

4.218 22.320 0.437

172.962

6.334 30.379

0.659 183.723

MEDIAN 487.572 VARIANCE 13516.949 F:AI"GE 414_108

MEDIAN I)ARIANCE RANDE

MEDIAN VARIAf-lCE RANGE

MEDIAN VARIANCE RANGE

441.904 8,-:'77.301

399.659

111.631 498.202

96.369

110.481 922.868 121.157

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Anhang 131

Arteriovenöse Oz-Gehaltsdifferenz (mI- dl- I)

AVD01

MEAH 3.671 STD ERR 0.143 MEDIAN 3.571 MO[oE 2.4:23 STD (IIE:V 0.755 \)C,RIAI'ICE 0.570 KURTOSIS -0.132 SKEWNESS 0.401 RANGE 2.948 MINIMUM 2.423 MAXIMUM 5.371

AVD02

REAN 3.'563 STIl ERR 0.204 ME1:tIAN 3.500 MODE 2.268 STD DEV 0.959 VARIANCE 0.919 KURTIJSIS 0.366 SKEWNESS 0.846 RAl'lGE 3.693 MINIMUM 2.268 MAXIMUM 5.961

Gemischtvenöse 02-Sättigung (%)

Sv02 1

MEAN 72.296 STIl ERR 0.825 ME[IIAN 71.9'::.Q MODE 70.000 STD DEV 4.368 VARIANCE 19.077 KURTOSIS -0.767 SKEWNESS -0.180 RANGE 16.700 MINIMUM 63.100 MAXIMUM 79.800

Sv02'2

MEAN 70.014 STD ERR 1.256 MEIIIAN 71.750 MODE '58.700 STD [OEV 5.893 \)AR!ANCE 34.727 KURTOSIS -0.957 SKEWNESS -0.454 RANGE 19.400 MINIMUM 58.700 MAXIMUM 78.100

Tabelle A 10a. Hämodynamische Veränderungen durch alleinige Volumengabe. Es sind jeweils die Parameter an Meßpunkt 1 und 2 angegeben

Herzfrequenz (min -1)

HI{ 1

MEAN 83.278 MODE 69.000 t<;URTOSIS 1.341 MINIM'JM 47.000

liR 2

MEAN 80.389 MODE .'>8.000 KURTOSIS 1.905 MINIMUM 62.000

STIl ERR STD DEV SKEWNESS MAXIMUM

STD ERR STD DEV SKEWNS::SS MAXIMUM

4.927 20.903

0.902 137.000

3.595 15.251

1.473 121.000

MEJ"tIAN VAF:IANCE F:ANGE

MEnIA'" VARIANCE RANGE

78.'500 436.918 90.000

75.500 232.604 59.000

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132 Anhang

Arterieller Mitteldruck (mm Hg)

MAP1

MEAI-I 98.111 MODE 96.000 t<:URTOSIS -0.078 MINIMUM 60.000

MAP2

ME Al'! 100.471 MODE 120.000 t<:Uf.:F)SIS 0.652 MINIMUM ,'>2.000

Systolischer Blutdruck (mm Hg)

SAP1

MEAN 153.444 MODE 148.000 KURTOSIS -0.859 MINIMUM 95.000

SAP2

MEAN 162.611 MODE 185.000 ":lIRTOSIS 0.010 MINIMUM 100.000

Diastolischer Blutdruck (mm Hg)

OAP 1

MFAN 65.389 MODE 50.000 KlIRTOSIS 0.205 MINIMUM 47.000

OAPQ

ME AN 0&.889 MorlE 61.000 t<:lIRTOSIS -'0.698 MINIMUM 53.000

STIl EF:k STD DEV SKEWNESS MAXIMUM

STIl EF:R STD DEV SKEWNESS MAXIMUM

STIl EF:R STD [IEV SKEWNESS MAXIMUM

STD ERR STD DEt) SKF.WNESS MAXIMUM

STIl ERR STD DEV SKEWNESS MAXIMUM

STIl ERR STD DEV SKEWNESS MAXIMUM

5.023 21.312 -0.044

140.000

3.926 16.187 -0.829

120.000

8.~29

35.337 -0.336

206.000

7.268 30.834 -0.671

214.000

3.003 1.2.742 0.565

95.000

2.,696 11.437

0",557 92.000

MEIIIAN ')AF:IANCE t=;:ANI3E

Mr:IITAN VARI(~I-ICE

RANGE

MEDIAN VARIANCE F:ANßE

MEDIAN V(~RIr-,NCE

RAtJGE

MEDIAN VARIANCE RANGE

MEIIIAN VARIANCE F:ANßE

96.500 454.221

BO.OOO

1.01.000 262.015 58.000

150.500 1248.730 111.000

16'5.500 950.720 114.000

63.500 ll,2.369 48.000

64.500 130.810

39.000

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Anhang 133

Zentralvenöser Druck (mmHg)

CVF'1

MEAM 3.059 STIl ERR 0.572 MEIIIAN 2.667 MODE 1.000 STD DEV 2.358 VARIAI'ICE 5.559 KURTOSIS -0.2"36 SKEWNESS 0.699 RANGE 8.000 MINIMUM 0.000 MAXIMUM 8.000

CVP?

MEAI-l 7.471 STIl ERR 0.892 MErIIAN 7.125 MODE: 7.000 STD DEV 3.676 VARIANCE 13.515 KURTOSIS 0.721 SKEW"'ESS 0.506 F:ANGE 15.000 MINIMUM 1.000 MAXIMUM 16.000

Pulmokapillarer Verschlußdruck (mmHg)

PCW1

MEAM" 6.611 STIl EF:R 0.71.9 MEDIAN 6.500 MODE 2.000 STD (lEI) 3.051 VARIANCE 9.310 KURTOSIS -0.442 SKEWNESS 0.12"3 RA!-lGE 10.000 MINIMUM 2.000 MAXIMUM 12.000

PCW2

MEAN" 15.167 STIl ERR 0.919 MEDIAN 15.7'':;0 MODE 16.000 STD DEV 3.899 VARIANCE 15.206 KUI:::TOSIS -0.171 SKE\.iNESS -0.141. F:ANGE 15.000 MINIMUM 8.000 MAXIMUM 23.000

Mitteldruck in der A. pulmonalis (mm Hg)

PAF'1

MEAM 16.722 STIl ERF: 1.148 I'IE!:.!AN 16.000 MODE 22.000 STD fiEl) 4.873 VARIANCE 23.742 KIJRTOS!S -1.282 SKEWNESS 0.104 F:ANGE 15.000 MINIMUM 9.000 MAXIMUM 24.000

PAP2

MEAM 24.889 STIl EF:R 1.134 MET/I AN 25.000 MODE 24.000 8TD [lEV 4.813 VARIANCE 23.163 KUIHOSIS ·-0.261 SKEWNESS -0.365 RANGE 17.000 MINIMUM 1.5.000 MAXIMUM 32.000

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134 Anhang

Herzindex (I. min -1. m -2)

Cll

MEAM 3.020 STIl ERR 0.200 t48:ftf'loN 2.8130

MOIIE 1.907 STD IIEV 0.850 VARI AHCE 0.722

KURTOSIS 5.084 SKEWNESS 1.906 RAHC--E 3.770

MINIMUM 1.907 MAXIMUM 5.678

CI2

MEAH 3.732 STIl ERR 0.22'5 t48HAH 3.567 MOIIE 2.212 STD [IEV 0.953 V,e..RIANCE 0.908

KURTOS!S -0.2:;>4 SKEWHESS 0.396 RAN!:'-.E 3.517 MINIMUM 2.212 MAXIMUM 5.729

Schlagindex (ml. min -1 . m -2)

S11

MEAH 36.701 STIl ERR 1.503 MEr'IA'" 37.638 MOttE 26.168 STD DEV 6.377 VAR I AHCE 40.661 KURTOSIS -1.393 SKEWHESS -0.161 RA!>!!3E 20.103 MINIMUM 26.168 MAXIMUM 46.271

SI2

'flEAM 46.127 STIIERR 1.522 MEII1AH 46.062 MOIIE 33.009 STD I1EV 6.458 VARIAHCE 41.703 KURTOSIS 0.719 SKEWHESS -0.305 RAH6E 25.971 MINIMUM 33.009 MAXIMUM 58.980

Schlagarbeitsindex des linken Ventrikels (g·m.m-~

LVSI1

MEAH 46.347 STD ERR 3.468 MEIIIAN 44.593 MODE 20.315 STDIlEV 14.713 VAR I AHCE 216.476 KURTOSIS -0.871 SKFWHESS -0.210 RAHC-.E 48.737 MINIMUM 20.315 MAXIMUM 69.051

LVSI2

MEAH 52.7B9 STIl ERR 2.49-S MEIIIAN 55.203 MOllE 24.414 STD IIEV 10.287 VARIANCE 105.827 KIJRTOSIS 3.069 SKEWNESS -1.032 RAHBE 47.777 MIHIMUM 24.414 MAXIMUM 72.192

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Systemischer peripherer Gesamtgefäßwiderstand (dyn. s· cm -s . m -~

SVRl

MEAN 1287.108 STIl ERP. 68.165 MOIIE 806.850 STIl DEV 24'5.771 KURTOSIS -0.782 SKF.\JNESS -0.670 MINIMUM 806.850 MAXIMUM 1556.280

SVR2

MEAN 1119.921 STIl ERR 83.854 MOllE 564.200 STIl DEV 324.766 KIJRTOSIS 1.258 SKE\JNESS 0.667 MINIMUM 564.200 MAXIMUM 189'5.170

Druck-Frequenz-Produkt (mm Hg. min -I)

RPP1

MEAN 11911.2Q3 STIl ERR 857.231 MOIIE 7488. f)00 STIl DEV 35'34.456 KURTOSIS 3.020 SKF.\JNESS 1.554 MINIMUM 7488.000 MAXIMUM 21708.000

RPP2

HEAN 13162.441 STIl ERR 978.125 MODE 7800.000 STD [IEV 4149.836 KURTOSIS 1.482 SKE\JNESS 1.325 MINIMUM 7800.000 MAXIMUM 22898.000

Koronarer Perfusionsdruck (mm Hg)

CPP1

HEAN 56.941 STIl ERR 2.559 MOIlE 43.000 STD DEV 10.550 KIJRTOSIS -0.817 SKE\JNESS -0.149 MINIMUM 38.000 MAXIMUM 75.000

CF'P2

MEAN -:;3.722 STD ERR 2.541 MOI:IE 45.000 STIl DEV 10.780 KURTOSIS 0.142 SKE\JNESS 0.435 MINIMUM 34.000 MAXIMUM 77.000

Anhang 135

MEIIIAH 139'3.820 VARIANCE 60403.285 RANGE 749.430

MEIIIAN 1120.570 VARIANCE 105473.250 RANGE 1330.970

MF.DIAN 11250.000 VARIANCE*492376.000 RANGE 14220.000

MEIt I AN 12037 • ~.()O VARIANCE*221168.000 RAN8E 15098.000

MElHAN 58.000 VARIANCE 111.309 P.ANGE 37.000

ME!IIAN 51..500 VARIANCE 116.212 RANGE 43.000

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136 Anhang

Tabelle A lOb. Veränderungen der OrTransportvariablen durch alleinige Volumenga­be. Es sind jeweils die Parameter an Meßpunkt 1 und 2 angegeben

OrAngebot (ml·rnin-'·m-)

D02 1

MEAN 461.860 STIl ERR MODE 283.528 STD IIEV I<URTOSIS 0.923 SKEWNESS MINIMUM 28'3.528 MAXIMUM

002 .2

Mf:.AR 488.914 STIl ERR MODE 268.549 STD DEV KURTOSIS 0.326 SKEWHESS MINIMUM 268.549 MAXIMUM

OrVerbrauch (ml·min- ' .m-2)

V021

MEAH 114.845 STD ERR MOllE 72.447 STIl IIEV KURTOSIS 0.321 Sl<El.INESS MINIMUM 72.447 MAXIMUM

V022

MEAN 119.394 STIl ERR MOllE 69.422 STD DEV KURTOSIS 0.954 SKEWNESS MINIMUM 69.422 MAXIMUM

Arteriovenöse OrGehaltsdifferenz (ml.dl- ')

AVlIOl

MEAN '3.887 STD ERR MOllE 2.456 STIl IIEV KURTOSIS 1.496 SKEWNESS MINIMUM 2.456 MAXIMUM

AVOO2

MF.AN 3.217 STIl ERR MODE 2.433 STD IeEV '(URTOSIS -0.385 Sl<EWNESS MINIMUM 2.433 MAXIMUM

28.369 116.970

0.827 741.462

29.740 118.962 -0.120

716.376

7.218 30.624 0.783

187.1'53

9.292 :35.181

1.034 204.385

0.200 0.848 0.524 6.056

0.122 0.:518 0.299 4.206

MEIIIAN 449.619 VARIANCE 1~682.090 RANGE 457.934

MEIIIAN 489.818 VARI ANCE 14151.941 RANGE 447.828

MEIIIAN t07.875 V~RIANCE 937.81t RANGE 114.706

MEIIIAN 108.088 VART.ANCE 1237.709 RANGE 134.962

MEDIAN '3.891 VARIANCE 0.720 RANGE 3.600

I'IEIIIAN 3.197 VARIANCE 0.269 RANGE 1.n3

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Anhang 137

Gemischtvenöse Oz-Sä~gung (%)

Sv02 1

I'IEAM 70.600 STIl ERR 1.098 MFIIIAM 70.800 MOttE 72.200 STIl DEV 4.528 VARIANCE 20.504 KURTOSIS 2.42<;- SKElJMESS -0.8'50 RAI"GE 19.900 MINIMUM 58.400 MAXIMUM 78.300

Sv02 2

HF.AM 71.787 STIl ERR 0.970 MF.J:tIAM 70.900 MOttE 70.900 STIl DEV 3.881 VARIANCE 15.061 KURTOSIS 1.025 SKElJMESS -0.262 RANGE 16.200 MINIMUM 62.700 MAXIMUM 78.900

Tabelle A 11. Häufigkeit des Einsatzes von vasoaktiven Substanzen und ß· Blockern innerhalb der einzelnen Narkosegruppen. Bezogen auf die Meßpunkte 1-16

Substanzen und Halo NLA PDA+ITN Signifikanzunterschiede

n [%] n [%] n [%]

Acebutolol (0,1) 11 (0,7) (0,1) PDA vs. Halo n.s. Halo vs. NLA p<O,OI PDA vs. NLA p<O,OI

Noradrenalin (0,1) 3 (0,2) 14 (0,8) PDA vs. Halo p<O,OI Halo vs. NLA n. s. PDA vs. NLA p<O,OI

Dopamin8 40 (2,4) 14 (0,8) 36 (2,1) PDA vs. Halo n.s. Halo vs. NLA p<O,OOI PDA vs. NLA p<O,OOI

Nitroglyzerin 61 (3,6) 71 (4,2) 12 (0,7) PDA vs. Halo p<O,OOI Halo vs. NLA n. s. PDA vs. NLA p<O,OOI

8 Es wurden nur Dopamindosierungen > 3 J,Lg/kg KG/min berücksichtigt.

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Sachverzeichnis

Analgesie 15 Aorta 51 -, Abklemmen 2,48-50,57-62,85 -, Aneurysma 22, 51, 58 -, Freigabe 62-65 -, -, Hypervolämie 63 -, -, Hypovolämie 63 arterielle Drücke 29, 30 - -, diastolische 28, 32 --,mittlere 23,24,31,32,49,53,64 - -, systolische 23, 28 arterielle Verschlußkrankheit 2, 58 --, abd. Aortenaneurysma 2 - -, Aortoiliakalbereich 2, 22 - -, Begleiterkrankungen 2 arterieller OrGehalt 19,39,74 --, Berechnung 19 arteriovenöse OrGehaltsdifferenz 19,26,29,

41,42,49 --, Berechnung 19 Aufwärmereaktionen 15,52,72,73,78,86 -, Halothan 78 -,PDA 85 Auskühlung s. Hypothermie autonomes Nervensystem 53 --, Gefäßtonus 3 --, Herzleistung 3

Baroreflex 56, 62, 65, 79, 82 Basendefizit 15 Basenüberschuß 44, 46 Beatmung 11, 43 -, art. pC02 42, 52 Bupivacain 11

Diazepam 11,71 Diuretika 15 Droperidol 10,61,80,81 Druck-Frequenz-Produkt 18, 24, 25, 28, 31,

38,49, 55, 59,62,64,67, 81, 82 -, Berechnung 18

EKG 17 -, Vs-Ableitung 17 Extubation 12 Exzeßlaktat 47, 57, 74

Fentanyl 10, 56,61, 80, 81 Flüssigkeits- u. Volumensubstitution 12, 13 Frank-Starling-Mechanismus s. Ventrikelfunk-

tion

gemischtvenöse 02-Sättigung 26, 29, 42, 43, 44, 64

Halothannarkose 2,29-50,61-71,74,78,81, 85,86

-, Durchführung 11 Hämodynamik s. Kardiozirkulation Herz s. Myokard Herzauswurfvolumen 4, 72 -, Bestimmung 9 -,02-Angebot 67 -,OrVerbrauch 72 -, Umverteilung 4,61,69, 76 Herzfrequenz 17,23,24,28,30,31,49,53,

68,69 -, Abklemmen der Aorta 59 -, Freigabe der Aorta 64 -, Reduzierung 53, 54 -, Sympathikusblockade 53 Herzindex 18, 24, 28, 34, 49, 59,70, 80 -, Berechnung 18 Hypothermie 12, 52

Intubation 10, 11

Kardiozirkulation -, Adaptation 2,4, 5, 6, 54, 55, 56, 81 -, Diazepam 72 -, Hypotension 62, 65 -, Intubation 56 -, Lachgas 72 -, Laryngoskopie 56, 57 Katecholamine -, Ausscheidung 76 -,exogene 84 -, zirkulierende 5, 54, 76 Kontrollmessungen 51 koronare Herzkrankheit 2, 69, 86 - -, Aneurysma 60 --, arterielle Verschlußkrankheit 2,60 koronarer Perfusionsdruck 18, 24, 25, 28, 32,

38,39, 55, 59, 64, 67, 69, 81

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154 Sachverzeichnis

laborchemische Bestimmungen 9 Lachgas 10, 11, 12,61,71, 72, 73, 81, 86 Laktat 9, 44, 46, 72 Laryngoskopie 56, 57, 80 Letalität 22, 62, 83, 87 -, Aortenaneurysma 83, 84 -, AVK 83,84 -, Myokardinfarkt 84 -, Nierenerkrankung 83 -, Reoperation 83

Medikamente -, präoperative 7,8 Metabolismus s. Stoffwechsel Monitoring 8,9, 87 -, Katheter 16 -, Meßpunkte 16 Mortalität, perioperative s. Letalität Myokard -, Adaptationsfähigkeit 55 -, Angina pectoris 67 -, Auswurfimpedanz 20, 57, 58, 60, 70 -, Belastung 59 -, Compliance 20 -, Infarkt 2, 23, 66, 70 -, Inotropie 60, 67 -, Insuffizienz 3, 5, 58, 60, 62, 76, 77, 86 -, Ischämie 3, 17,61,66,68 -, Kontraktilität 18, 19,54,62,67-71,85 -, Koronarzirkulation 68, 69 -, Leistungsfähigkeit 3, 19,20,25, 54, 69, 70 -,OrBilanz 2, 3, 17, 55, 62, 66 -,02-Verbrauch 18,57,66,67,68,72,81,85 -, Rhythmusstörungen 61,62 -, Vorerkrankung 58

Narkosedauer 22 Natriumbikarbonat 15, 63, 79 Nervi accellerantes 6 Nervi spalnchnici 6 Neuroleptanalgesie 2,27,29-50,56, 57,

61-71,74,78,79,85 -, Durchführung 10 -, Herzinsuffizienz 86 Nitroglycerin s. Vasodilatatoren NLA s. Neuroleptanalgesie

02-Angebot 2, 26, 27, 29, 40, 44, 49, 52, 55, 64,75

-, Berechnung 19 -, kritisches 73, 74 -, Mißverhältnis zu 02-Verbrauch 2 OrAusschöpfung s. OrExtraktion OrExtraktion 27,42,49, 56, 57, 65, 66, 68,

74,76,78 Oz-Verbrauch 2,4,26,27,29,40,41,44,49,

54,55,57,64,72,73,75,78,80,85

-, Berechnung 19 -, Mißverhältnis zu Oz-Angebot 2, 4, 5 Operation -, Dauer 22 -, Indikation 22 -, Komplikationen 23 -, Revision 23 -, Technik 12, 22

Pancuronium 10, 11 Parasympathikus 4, 5, 53, 69 PDA s. thorakale PDA Periduralanästhesie s. Periduralanalgesie perioperative Phase 4 pH-Wert 43,45 Prämedikation 8 Pufferung s. Basendefizit pulmokapillarer Verschlußdruck 12, 14, 18,

19,24,28,31,33,49,52,58 - -, Abklemmen der Aorta 58, 59 --, Freigabe der Aorta 64 pulmonalarterieller Mitteldruck 27, 33 Pyruvat 9, 46, 47

Randomisierung 7, 22, 51 Relaxierung 10, 11 ß-Rezeptoren -,Blockade 5,67 -, Blocker 14,67, 75 Risikopatient 1 -, kardialer 1, 84

Schlagarbeitsindex d. li. Ventrikels 18,24,28, 34, 35, 36, 49, 59, 64, 70, 80

---, Berechnung 18 Schlagindex 18, 24, 34, 35, 59 -, Berechnung 18 Sedierung -, intraoperative 11 -, postoperative 15 Shivering s. Aufwärmereaktionen Spinalanästhesie 5 Statistik 20, 21 Stoffwechsel 43-48 -, anaerob 4, 56 Suxamethoniumchlorid 10, 11 sympathikoadrenerge Reaktionen s. Sympathi-

kus Aktivierung sympathikoadrenerges System s. Sympathikus Sympathikolyse s. Sympathikusblockade Sympathikomimetika 14 Sympathikotonus s. Sympathikus Sympathikus -, Aktivierung 68,69,72,76,81 -, Allgemeinanästhetika 6, 56 -, Efferenzen 56, 68, 69 -, Herzinsuffizienz 76, 84

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-, Herz-Kreislauf 4 -, peripherer 4,55,56 -, Vasokonstriktion 5, 68 -, zentraler 2, 6, 55, 56, 71, 79, 84 Sympathikusblockade -, Allgemeinnarkose 6 -,Herzfrequenz 53,54 -, Herzinsuffizienz 77 -, Hypotension 6 -, Hypoxie 77 -, kapazitives Gefäßsystem 55, 69 -, Komplikationen 5, 6 -, Nachlastreduzierung -, segmentäre 2, 5, 6, 63, 65, 67, 70, 71, 78 -, totale 75 -, Vasokonstriktion 54 systemischer peripherer Gesamtgefäßwider­

stand 18, 20, 24, 25, 28, 36, 49, 54, 57, 59, 62, 64, 70, 80, 81

---, Berechnung 18

Thiopental 10, 11, 56, 80 thorakale PDA 1, 52-56 --, Kardiozirkulation 24,25,26 --, Sauerstoffiransport 26,27 thorakale PDA mit Allgemeinanästhesie 1, 2,

6,29,50,56, 57,61-71,74,81,84,85,86

Sachverzeichnis 155

---, Durchführung 11 ---, Hämodynamik ---, -, perioperativ 27,29-38 ---, -, präoperativ 23-26 - - -, Metabolik 43-48 ---, Sauerstoffiransport ---, -, perioperativ 27,29-39 - - -, -, präoperativ 23, 26, 27

Urinausscheidung 70,71

Vasodilatatoren 14,61,63 Ventilation s. Beatmung Ventrikelfunktion 5, 19,20,25,26,30,37,50,

54,56,57,60,63,65,67,70 Volumengabe 52 -, mit PDA 27, 28 -, ohne PDA 27, 28

Wiedererwärmung s. Aufwärmereaktionen

zentralvenöser Druck 12,17,24,28,31,32, 33,49,52

- -, Abklemmen der Aorta 58, 59 --, Freigabe der Aorta 64 Zufallsprinzip s. Randomisierung