JOINT ANNUAL MEETING OF IMMUNOLOGY OF THE AUSTRIAN … · arising not only in basic innate and...

Österreichische Gesellschaft für Allergologie und Immunologie&

Deutsche Gesellschaft für Immunologie

JOINT ANNUAL MEETING OF IMMUNOLOGY

OF THE AUSTRIAN AND GERMAN SOCIETIES

Lecture Centre of the Vienna General HospitalVienna, Austria

Wednesday, September 3 – Saturday, September 6, 2008

Final Programme

www.medacad.org/oegai2008

ALLERGIE LAUF

Sonntag, 7. September 2008 Schlosspark Schönbrunn

Hiermit laden wir Sie ganz herzlich dazu ein, im Anschluss an den Kongress „Joint Annual Meeting of Immunology, Wien, 3.-6. September 2008“, am

ALLERGIE LAUF am Sonntag, 7. September 2008 im SCHLOSSPARK SCHÖNBRUNN,

einer der schönsten Parkanlagen Wiens, teilzunehmen. Nach dem Startschuss von Nobelpreisträger Peter Doherty geht es durch den Schlosspark Schönbrunn, durch Alleen mit barocker Gartenbaukunst, und vorbei am Schloss Schönbrunn, einem der bedeutendsten Kulturdenkmäler Österreichs, einst bewohnt von Kaiserin Sissi und heute ein beliebtes Ausflugsziel vieler Wiener und Wienbesucher. Sie können unter verschiedenen Distanzen wählen und auch im Team laufen. Das Tempo bleibt Ihnen überlassen: gemütlich oder mit sportlichem Ehrgeiz, dazu wird es eine exakte elektronische Zeitmessung geben. Ob Kongressteilnehmer oder nicht - es sind alle eingeladen, mit zu laufen. Im Anschluss an den Lauf folgen als Krönung des Tages und als Belohnung für Ihren sportlichen Einsatz und das tüchtige anfeuern Ihrer Fans, die After Running Party, die Siegerehrung, eine Tombola, ein Buffet reich an köstlichen typisch österreichischen Gerichten, und eine Musikshow. Es unterhalten Sie Harry Sonnek und der legendäre Dave Dee, der mit seinen besten Songs aus den 60ern aus London zu uns kommen wird und für die richtige Partystimmung sorgen wird. Zur After Running Party sind alle Läufer und deren Begleiter ganz herzlich eingeladen. Bitte nutzen Sie die Möglichkeit der Online-Anmeldung auf www.medacad.org/oegai2008 unter „Allergy Run“ sobald als möglich, damit Sie sich Ihr, in der Gebühr inkludiertes, Erinnerungs- T-Shirt in der richtigen Größe sichern. Auf der Homepage finden Sie auch alle mit dem Lauf verbundenen Informationen, sowie den vorläufigen Streckenplan.

Wir freuen uns auf zahlreiche Anmeldungen!

www.bundesgaerten.at

Österreichische Gesellschaft für Allergologie und Immunologie&

Deutsche Gesellschaft für Immunologie

JOINT ANNUAL MEETING OF IMMUNOLOGY

OF THE AUSTRIAN AND GERMAN SOCIETIES

Lecture Centre of the Vienna General HospitalVienna, Austria

Wednesday, September 3 – Saturday, September 6, 2008

Final Programme

www.medacad.org/oegai2008

Table of Contents

General

Patronage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2

Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2

Welcome Addresses . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3

Committees – Board – Organisation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5

Programme at a Glance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6

Scientific Programme

- Wednesday, September 3, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8

- Thursday, September 4, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9

- Friday, September 5, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15

- Saturday, September 6, 2008 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20

Poster Viewing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25

Business Meetings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26

Satellite Lunch Symposia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27

Information on Posters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28

Information for Speakers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 29

Information

Congress Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30

Registration Fees . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 32

General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33

Venue . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 35

Social Events . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 37

Underground Map . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38

City Map . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 39

Exhibition

Exhibition – General Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 40

List of Sponsors, Exhibitors and Advertisers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 41

1

Patronage

Under the Patronage of

Dr. Alfred GusenbauerFederal Chancellor of the Federal Republic of Austria

Dr. Johannes HahnFederal Minister for Science and Research

Dr. Andrea KdolskyFederal Minister for Health, Family and Youth

Mag. Sonja WehselyExecutive City Councillor for Public Health and Social Affairs

Acknowledgements

The Joint Annual Meeting of Immunology gratefully acknowledges the support of the followinginstitutions, companies and organisations (list correct as per date of printing):

2

Welcoming Addresses

Unquestionably a high level of health care is the core element of our modernwelfare system as we know it. It is therefore our duty as politicians to securethe basis for its long-term financial stability. Furthermore, we must create aninstitutional and legal framework to guarantee universal and non-discrimina-tory access to all forms of treatment. Nobody should be excluded or left behind. Only under these conditions can health-care professionals fulfil theiressential duty and live up to their oath i.e. helping people.

Public opinion polls show the high satisfaction of Austrians with our nationalhealth care system. But no society can satisfy itself with self appreciation. Many challenges lieahead of us. Some are institutional, financial, others are scientific. This congress will help to pro-mote knowledge and hopefully inspire all working in your field.

On behalf of the Austrian government it is my pleasure to welcome you here in Austria and inparticular at this “Joint Annual Meeting of Immunology”.

Dr. Alfred GusenbauerFederal Chancellor of the Federal Republic of Austria

More than 1000 participants at the „Joint Annual Meeting of lmmunology"give invigorating proof of the importance and international reputation of theSocieties of Allergology and Immunology in Austria and Germany on the onehand and the Vienna Medical Academy in the fields of education/research aswell as conference and association management – an organisation dedicatedto serving the needs of the medical non-profit community - on the other. Asminister of Science and Research it is good news for me that internationalexperts are discussing such pressing topics as vaccination, infection and allergy just now in Austria. That means new incentives for the Scientific Com-

munity especially in our country and the opportunity to expand international networking. Theseissues are of great relevance for nearly all of us and the expectations are very high, if you only thinkof tumor immunology for example. May the meeting be a successful one with impressing resultsand congratulations on bringing together university professors of international reputation in thisfield in Vienna for the first time. In this way the meeting is a great recognition of Vienna as an im-portant medical research place.

Dr. Johannes HahnFederal Minister for Science and Research

3

Welcoming Addresses

Dear colleagues and scientific friends,

It is our great pleasure to welcome you to the Joint Annual Meeting of the Austrian and the Ger-man Societies of Immunology in Vienna.

The annual conferences of our societies allow for an exchange of thoughts and information on cut-ting edge developments taking place in the immunological laboratories worldwide. The format ofa joint annual conference allows for an expansion of this exchange into a neighbouring countryand likewise fosters new and/or permits to renew longstanding scientific and social relationships.

With this meeting we are aiming to delineate the latest progress in our field, focusing on mattersarising not only in basic innate and adaptive immunity, but also clinical immunology includingnovel therapeutic approaches. The scientific committee has invited outstanding scientists to pres-ent their thinking and to summarize data on their advances in plenary sessions and introductionsto workshops. Within workshops and during the poster sessions, there will be ample opportunityespecially for students and postdoctoral fellows to present their newest research results and thusa broad array of work which is performed in the realm of the hosting societies and beyond.

We have made all efforts to create a scientific program that meets your expectations. In additionyou shall enjoy Vienna´s ambience and hospitality, the unique culture and spirit which so fewother cities have to offer.

With best wishes for a scientifically exciting and stimulating meeting and

mit herzlichen Grüßen,

Yours

Stefan Meuer & Josef Smolen

4

Committees – Board – Organisation

Congress Committee

Stefan C.W. Meuer Josef SmolenAndreas Radbruch Marcus SäemannReinhold E. Schmidt

Local Organising Committee

Irmgard Förster Marcus SäemannBeatrix Grubeck-Loebenstein Reinhold SchmidtErika Jensen-Jarolim Josef SmolenStefan C.W. Meuer Hannes StockingerWinfried Pickl Rudolf ValentaAndreas Radbruch Gerhard Zlabinger

ÖGAI Executive Committee

Josef Smolen (President) Gernot Achatz (Board Member)Rudolf Valenta (President Elect) Hans-Peter Brezinsek (Board Member)Beatrix Grubeck-Loebenstein (Past President) Roswitha Gruber-Sgonc (Board Member)Marcus Säemann (Secretary General) Erika Jensen-Jarolim (Board Member)Winfried Pickl (Deputy Secretary) Johannes Stöckl (Board Member)Tamara Kopp (Secretary Protocol) Martin Thurnher (Board Member)Barbara Bohle (Treasurer) Othmar Förster (Honorary President)

DGfI Executive Committee

Stefan C.W. Meuer (President) Reinhold Förster (Board Member)Andreas Radbruch (President Elect) Stefan H. E. Kaufmann (Board Member)Reinhold E. Schmidt (Past President) Heidrun Moll (Board Member)Werner Solbach (Secretary General) Yvonne Samstag (Board Member)Christian Bogdan (Board Member) Burkhart Schraven (Board Member)Barbara Bröker (Board Member) Hans Dieter Volk (Board Member)Stefan Ehlers (Board Member) Hans-Martin Jäck (Board Member)Irmgard Förster (Board Member)

Conference Organisation, Abstract Management, Sponsoring

Vienna Medical AcademyMs. Marieke HodelAlser Strasse 4, 1090 Vienna, AustriaPhone: +43 1 405 1383-10; Fax: +43 1 407 8274E-mail: [email protected]

Exhibition Management Hotel Accomodation

Medizinische Ausstellungs- und Mondial Congress & EventsWerbegesellschaft MAW Operngasse 20bFreyung 6 1040 ViennaA-1010 Vienna, Austria Phone: +43 1 58804-0Phone: +43 1 536 630 Fax: +43 1 58804-185Fax: +43 1 535 60 16 Email: [email protected]: [email protected]

Congress Venue

Lecture Centre of the Vienna General Hospital(Allgemeines Krankenhaus - AKH)Währinger Gürtel 18-201090 Vienna, Austria

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Scientific Programme – Wednesday, September 3, 2008 8

Time Lecture Hall 1

15.00-

15.10

WelcomeChair: S. Meuer, J. Smolen

Welcoming addresses by

Stefan Meuer, President DGfI

Josef Smolen, President ÖGAI

15.10-

15.25

Karl Landsteiner (1868-1943) - An Austrian Immuno-PathologistGabriela Schmidt-Wyklicky

15.25-

15.45

Awarding of the Landsteiner Price of the DGfI to Max CooperLaudatio: Andreas RadbruchAward Lecture: Max Cooper

15.45-

16.05

Awarding of the Landsteiner Medal of the ÖGAI to Ron GermainLaudatio: Clemens ScheineckerAward Lecture: Ron Germain

16.05-

16.20

Rainer Honeck, Concert Master of the The Vienna Philharmonic Orchestra: J.S. Bach

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16.50

Keynote Lecture:Nobel laureate Peter Doherty

16.50-

17.00

Rainer Honeck, Concert Master of the Vienna Philharmonic Orchestra: F. Kreisler

17.00-

17.15

Opening by Wolfgang Schütz (Rector of the Medical University of Vienna)

17.15 Welcome Drinks

Scientific Programme – Thursday, September 4, 2008 9

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3

08.15-

09.30

Parallel Symposium 1:T-Cell SignalingChair: W. Pickl, D. Kabelitz

Parallel Symposium 1:Innate Immunity: Antigen-Presenting-CellsChair: G. Stingl, B. Broeker

Parallel Symposium 1:Tumor ImmunologyChair: E. Jensen-Jarolim, G. Riethmüller

Molecular determinants of Inside-out signaling in T-cellsB. Schraven

DC dependent maintenance of peripheralregulatory T-cellsS. Beissert

Human Self/Tumor Antigens and TumorImmunosurveillanceO.J. Finn

From T cell activation signals to signalingcontrol of anti-cancer immunityJ. Penninger

Role of antimicrobial peptides in triggeringautoimmunityM. Gilliet

The immune response to sporadic cancerT. Blankenstein

Deciphering TCR ligand discrimination bycombining experiments, computer modeling, and predictive simulationsR. Germain

TLR-activated dendritic cells as effectorcells of the immune responseG. Stingl

Development of DNA vaccination strate-gies for pediatric cancersH.N. Lode

09.30-

10.30Coffee Break / Poster Viewing / Exhibition

Scientific Programme – Thursday, September 4, 2008 10

Time Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5

10.30-

12.15

T-Lymphocytes IChair: G. Schütz, H. Wolf

Autoimmunity IChair: H. Strobl, G. Beilhack

Tumor ImmunologyChair: J. Singer, T. Weichhart

ImmunomodulationChair: K. Loser, W. Berger

Innate Immunity: Anti-gen-Presenting CellsChair: N. Romani, H. Schild

1. Increased Th17 anddecreased CD4+FoxP3+T regulatory cells in thirdtrimester pregnancieswith pre-eclampsiaB. Santner-Nanan, M. Peek, L. Richarts, R. Khanam, E. Zhu, B.Fazekas de St. Groth, R. K. Nanan

9. The role of B cells intissue draining lymphn-odes for the develop-ment of collageninduced arthritis (CIA)C. Scheinecker, A. Rapp, M. Bonelli, A. Savitskaya, J. S. Smolen

17. Higher avidity ofTCR-gene-modified Tcells by using parts ofthe murine constant TCRregionsD. Sommermeyer, W. Uckert

25. Regulation of homingreceptor expression inCD4+ T cellsB. A. Ratsch, C. Doebis,S. Jennrich, S. Floess, A. Hamann, U. Syrbe

33. Targeting ofHaemagglutinin antigento C-type Lectins onhuman Dendritic Cellselicits different T cell re-sponses in vitroG. F. Heidkamp, F. Nimmerjahn, A. Piperno, H. Zebroski,R. M. Steinman, M. C. Nussenzweig, D. Dudziak

2. Blockade of induciblecostimulator (ICOS) in-hibits accumulation ofpolyfunctionalTh1/Th17cCells and pre-vents autoimmune arthri-tisO. Frey, J. Meisel, L. Bruns, A. Hutloff, L. Morawietz, T. Kamradt

10. T helper cells only in-duce acute inflammationbut B cells are necessaryfor the induction ofchronic Antigen-inducedArthritisM. Janke, T. Hohnstein,L. Morawietz, A. Scheffold

18. Reprogramming Tcells to become MHC in-dependent - electropo-ration of RNA encodingchimeric antigen recep-torsN. Schaft, T. Schunder,C. Krug, S. Reuter, D. Kosmides, H. Abken,M. Kershaw, E. Kämpgen, G. Schuler,J. Dörrie

26. Regulated releaseand functional modula-tion of junctional adhe-sion molecule A bydisintegrin metallopro-teinasesJ. Pruessmeyer, R. Koenen, L. Fraemohs,O. Soehnlein, C. Weber,A. Ludwig

34. PPARgamma en-hances uptake andcross-presentation ofsoluble antigen in den-dritic cellsS. Hucke, J. Floßdorf, I. Dani, D. Thimm, A. Kautz, C. Kurts, P. Knolle, L. Klotz, S. Burgdorf

3. IRF4 is essential forIL-21-mediated induc-tion, amplification andstabilization of the Th17phenotypeM. Huber, A. Brüstle, A. Guralnik, A. Mahiny, E. von Löw, M. Lohoff

11. Crucial role of CCR4in the development ofexperimental CNS au-toimmune disease bymodulation of Treg cellcompartimentalizationJ. Alferink, D. M. Otte,K. Poppensieker, Ö. Yilmaz, A. Mildner, M. Prinz, W. Maier, A. Zimmer

19. Memory CD8+ T-cellmediated tumor rejectionis impaired in NKG2D-dysfunctional miceM. C. Banerjea, D. Sigurdardottir, B. Pömmerl, H. Rammensee, A. Steinle

27. Ontogeny of Langer-hans cells in prenatalhuman skinC. Schuster, C. Vaculik,C. Fiala, W. Eppel, S. Meindl, M. Imhof, A. Elbe-Bürger

35. Genomic RNA ofhuman rhinovirus - a”semi-danger-signal” fordendritic cellsC. Schrauf, S. Kirchberger, O. Majdic, J. Seipelt, J. Stöckl

4. Acid sphingomyeli-nase is a critical regula-tor of cytotoxic granulesecretion by primary TlymphocytesJ. Herz, J. Pardo, H. Kashkar, M. Schramm, E. Kuzmenkina, E. Bos,K. Wiegmann, R. Wallich, P. J. Peters,S. Herzig, E. Schmelzer,M. Krönke, M. M. Simon,O. Utermöhlen

12. Antigen-specificTGF -induced Treg sup-press Th17-mediatedautoimmune diseaseE. N. Huter, G. H. Stummvoll, E. M. Shevach

20. Rejection of estab-lished cancer: Lack ofIFN- , TNF- and Fas-lig-and but not perforin byeffector CD8+ T cells al-lows cancer to progressJ. J. Listopad, G. Willimsky, B. Silkenstedt, T. Kammertöns, T. Blankenstein

28. Requirement ofCCL17 for progressionof atopic dermatitis andcontact hypersensitivityin miceS. Stutte, N. Gerbitzki, I. Förster

36. Antagonism betweenGATA-1 and vitamin D3receptor in myelopoisisand dendritic cell subsetdifferentiationS. Taschner-Mandl, F. Göbel, M. Kumerz, J. Jurkin, C. Vaculik, S. Richter, C.Bieglmayer, A. Elbe-Bürger, H. Strobl

5. Adenosine regulatesCD8 T cell priming by in-hibition of membrane-proximal T cell receptorsignalingD. Stabenow, C. Linnemann, F. A. Schildberg, A. Schurich, S. I. Hegenbarth, L. Diehl, E. Endl, S. Lacher, C. E. Müller, J. Frey, L. Simeoni, L. Simeoni, B. Schraven,P. A. Knolle

13. The pathogenic roleof HnRNP-A2 in Pris-tane-induced arthritisM. H. Hoffmann, C.Baumann, B. Meyer, G. Steiner

21. Defects of the anti-gen processing machin-ery leading to T cellresistance of melanomacellsM. Keller, F. Ebstein, A. Paschen, E. Bürger,D. Schadendorf, P. M. Kloetzel, U. Seifert

29. Acid sphingomyeli-nase is required for effi-cient phago-lysosomalfusionM. Schramm, U. Karow,A. Haas, M. Krönke, O. Utermöhlen

37. Function of hypoxia-inducible factor (HIF)-1in dendritic cellsT. Köhler, R. S. Johnson, H. Weighardt, I. Förster

6. pSMAC formation inhuman peripheral bloodT-cells requires localiza-tion of the actin-bundlingprotein L-plastin to theimmunological synapseG. Wabnitz, P. Lohneis,H. Kirchgessner, Y. Samstag

14. The autoimmune reg-ulator Roquin-a cofactorfor miRNA function?E. Glasmacher, K. P. Höfig, E. Kremmer,V. Heissmeyer

22. Tumor-specific Thelper cells regulatetumor dormancy orprogress multistage car-cinogenesis through Tcell cytokinesH. Braumueller, T. Wieder, N. Bauer, M. Rocken

30. Phenotypic and mo-lecular analysis of anHLA Class II deficientpatient reveals a ho-mozygous nonsensemutation in the CIITAgene at amino acid posi-tion 381K. G. Schmetterer, M. G. Seidel, U. Körmöczi, K. Schwarz, S. Matthes-Martin, P. Steinberger,W. F. Pickl

38. Distinct mechanismof antigen routing andcross-presentation inLSECA. K. Schurich, J. Böttcher, S. Burgdorf,P. Penzler, S. Hegenbarth, D. Stabenow, A. Dolf, E. Endl, C. Kurts, P. A. Knolle

Scientific Programme – Thursday, September 4, 2008 (continued) 11

Lecture Hall 1 Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5

7. The effect of thymec-tomy in early childhoodon the naive T cell com-partment in later lifeM. Prelog, M. Keller, R. Geiger, A. Brandstaet-ter, R. Würzner, B. Grubeck-Loebenstein,L. B. Zimmerhackl

15. OSCAR, a key co-stimulation molecule forosteoclasts, is inducedin patients with rheuma-toid arthritisS. Herman, G. Krönke,R. Müller, J. Zwerina, K. Redlich, G. Schett

23. Identification oftumor antigens using an-tibodies induced by den-dritic cell (DC) basedvaccinesJ. Leitner, A. Stift, J. Friedl, R. Pfranger, P. Steinberger, K. Pfistershammer

31. Different mecha-nisms of immunosup-pression caused byCyclosporine A (CsA)and FK506T. Giese, C. Sommerer,C. Jacobi, M. Zeier, S. Meuer

39. Skin dendritic cellspresent lipid antigens tonatural killer T cellsP. Stoitzner, I. F. Hermans, N. Romani

8. Clonal evolution of theeffector T cell repertoireD. Zehn, M. J. Bevan

16. Imaging immune-neuronal interactions inexperimental auto -immune encephalo -myelitis using intravitaltwo- photon microscopyV. Siffrin, J. Herz, T. Leuenberger, A. U. Brandt, H. Radbruch, R. Niesner, C. Infante-Duarte, F. Zipp

24. Serological relation-ship between cutaneoushuman papillomavirustypes 5, 8 and 92A. Handisurya, C. Schellenbacher, R. Gambhira, S. Shafti-Keramat, O. Forslund, M. Favre, R. Kirnbauer

32. Identification of threenovel genes as biomarker for monitoringanti-TGFbeta therapyS. Classen, C. Muth, D. Eggle, M. Beyer, T. Zander, A. Staratschek-Jox, J. L. Schultze

Time Lecture Hall 1

12.15-

13.45

Satellite Lunch Symposium - RocheB cell: Promising target in autoimmune diseasesChair: J. Smolen

The biology of the B cell in autoimmune diseasesA. Radbruch

Clinical experiences with B cell therapiesT. Dörner

Safety: Experiences with RituximabH-P. Brezinsek

12Scientific Programme – Thursday, September 4, 2008


14.00-

15.30

T-Lymphocytes IIChair: M. Lohoff, A. Thiel

Vaccines & AdjuvantsChair: B. Grubeck, S. Weiss

Signal TransductionChair: T. Bürckstürmer, T. Stulnig

NK cellsChair: C. Watzl, M. Fischer

Veterinary ImmunologyChair: A. Saalmüller, M. Müller

40. Stability and flexibil-ity of CD4 T cell differen-tiation programs in vitroand in vivoA. N. Hegazy, H. Hengartner, R. M. Zinkernagel, A. Radbruch, M. Löhning

48. Improvement of theImmunogenicity of aHIV-1 Clade C Candi-date Vaccine increasingGag, Pol, Nef and EnvSpecific T-Cell Re-sponsesJ. Wild, J. Koestler, S. Bredl, K. Boeckl, R. Wagner

56. Oxidation of cofilinmediates T cell hypore-sponsiveness under ox-idative stress conditionsM. Klemke, G. Wabnitz,F. Funke, B. Funk, H. Kirchgessner, Y. Samstag

64. The stress-inducibleendogenous danger sig-nals HSP70 and MICAsynergistically activatethe cytotoxic effectorfunctions of human NK cellsL. Elsner, P. F. Flügge, J. Lozano, V. Muppala,S. Y. Demiroglu, D. Malzahn, H. Bickeböller,G. Multhoff, L. Walter, R. Dressel

72. Charakterization ofthe chicken CD40-CD40L system unsingthe RCAS retroviral genetransfer technologyK. Schenk-Weibhauser,J. Young, B. Kaspers, S. Kothlow

41. On the role ofadipokines in Th2 lym-phocyte polarizationA. Batra, B. Okur, J.Ihbe, T. Stroh, R. Glauben, I. Fedke, M. Zeitz, B. Siegmund

49. Safety and immuno-genicity in a phase Idose-escalation BPV-1VLP vaccine trial inhorsesR. Kirnbauer, S. Brandt,S. Shafti-Keramat, E. K. Hainisch

57. The orphan adapterprotein SLY1 as a novelanti-apoptotic protein re-quired for thymocyte de-velopmentB. Reis, D. Finkenstaedt,D. K. Finlay, D. A. Cantrell, K. Pfeffer,S. Beer

65. Regulation of NK cellactivity through extracel-lular HLA-B-AssociatedTranscript 3E. Pogge von Strand-mann, V. Simhadri, K. S. Reiners, H. P. Hansen, A. Engert

73. Analysis of potentialantiviral MX activity inthe chickenB. Schusser, N. Penski,A. Reuter, G. Kochs, P. Staeheli, B. Kaspers,S. Kothlow

42. In vivo generatedTh17 cells have a stablememory for IL-17 ex-pressionM. H. Lexberg,I. Albrecht, A. Förster, A. Richter, A. Radbruch,H. D. Chang

50. Characterisation ofeffects on growth ofStaphylococcus aureusmediated by specificIgGsB. Tosetti, E. Glowalla,M. Krönke, O. Krut

58. Micropatterning ofCD4 in the live cellplasma membrane re-veals novel bindingmechanisms to LckM. Schwarzenbacher,M. Kaltenbrunner, M. Brameshuber, C. Hesch, W. Paster, J. Weghuber, B. Heise,A. Sonnleitner, H. Stok-kinger, G. J. Schütz

66. Natural killer cell’sactivation by Im-munomodulin for treat-ment strategy ofrecurrent genital herpesV. Garib, U. Djabborov,Y. Rasul-Zade

74. MHC typing in swine:SLA class I and class II-allele distribution in Aus-trian Large White,Landrace, and Pietrainbreeding stocksS. E. Hammer, J. Deutsch, B. C. Rütgen, S. Groiß,W. Gerner, S. Müller, A. Saalmüller

43. Role of HDAC in Thelper cell developmentR. Glauben, E. Sonnenberg, I. Fedke,P. Mascagni, M. Zeitz, B. Siegmund

51. Analysis of themechanisms mediatingdendritic cell-based vac-cination against Leish-mania majorJ. K. Schnitzer, C. Hambrecht, M. Fajardo-Moser, K. A. Remer, H. Moll

59. Stat3 serine 727phosphorylation uponactivated TLR bindingpromotes viaMyD88/TRIF safekeep-ing of IL-1betaS. Dreher, F. Schmitz, R. Ferstl, S. Spiller, J. Marges, A. Heit, I. För-ster, R. Lang, H. Wagner, C. J. Kirschning

67. Decision making inNK cellsD. Urlaub, S. Mesecke,H. Busch, R. Eils, C. Watzl

75. Porcine coccidiosis -adaptive immune re-sponse mechanismsagainst Isospora suisH. L. Worliczek, W. Gerner, A. Saalmüller,A. Joachim

44. HumanCD4+CD25+Foxp3+ regu-latory T cells efficientlyinhibit GvHD induction ina humanized mousemodelC. Becker, J. Kubach,C. Taube, C. Becker, K. Michel, K. Reifenberg,H. Jonuleit

52. Virus-like particles: Acell-free antigen-pre-senting platform modu-lating lymphocyteactivation in vitro and invivoH. J. Kueng, V. M. Leb,D. Haiderer, G. Raposo,C. Thery, S. V. Derdak, K. G. Schmetterer, A. Neunkirchner, C. Sillaber, B. Seed, W. F. Pickl

60. Carma1/Bcl10/Malt1Complexes TransmitITAM-coupled NK CellReceptor Signals for NF-B and MAPK ActivationO. Groß, C. Grupp, C. Steinberg, S. Zimmermann, D. Strasser, N. Hannesschläger, W. Reindl, C. Peschel,A. Krug, J. Ruland

68. Natural killer cells aremodulated in patientswith neuroimmunologicdisorders in response totreatment with intra-venous immunoglobulinC. Jacobi, M. Claus, B. Wildemann, J. Römisch, C. Watzl, S. Meuer, T. Giese

76. Potential diagnosticmarkers for subclinicalendometritis in cows:TNF-alpha, IL-1 alpha,IL-1 beta, and IL-8C. Gabler, M. Drillich, C. Fischer, C. Holder, W. Heuwieser, R. Einspanier

45. Mathematical model-ing of the diversity of theimmunological synapseM. T. Figge, M. Meyer-Hermann

53. Priming and boostingof melanA-specific Tcells - in vitro studies onthe importance of anti-gen-presentation densityJ. Dörrie, N. Schaft, V. Wellner, C. Wohn, T. Schunder, I. Müller, E. Kämpgen, G. Schuler

61. Functional analysisof the riboflavin kinaseand its role in TNF-in-duced signallingB. Yazdanpanah, C. Pongratz, K. Wiegmann, H. Kashkar, M. Krönke

69. Myeloid-Derived“Suppressor” Cells ex-press Rae-1 and activateNK cellsA. Cerwenka, E. Schlecker, I. Galani, N. Nausch

77. Toll-like receptor ex-pression and bacterialstrain dependentchemokine response in aprimary bovine colonicepithelial cell culturemodelP. S. Bridger, M. Mohr,J. Fröhlich, H. Metcalfe,D. Werling, G. Baljer,C. Menge

13Scientific Programme – Thursday, September 4, 2008 (continued)


46. The role of the zincfinger protein MAZR inCD4/CD8 cell fate deci-sions during thymocytedevelopmentS. Sakaguchi, I. Bilic, M. Hombauer, A. Schebesta, W. Ellmeier

54. Propagation-defi-cient LCMV-derived vac-cine vector efficientlytargets dendritic cells toinduce potent T and Bcell responses againstimmunogens of choiceL. Flatz, A. N. Hegazy, A. Verschoor, A. Bergthaler, M. Löhning, D. D. Pinschewer

62. The DEAD-box heli-case DDX3X is a criticalcomponent of the TANK-binding kinase 1-depen-dent innate immuneresponseD. Soulat, T. Buerckstuemmer, S. Westermayer, A. Goncalves, A. Bauch,A. Stefanovic, O. Hantschel, K. L. Bennett, T. Decker,G. Superti-Furga

70. Characterization of anovel, RORgt-expressingmucosal NK cell popula-tionS. L. Sanos, A. Mortha,V. Bui, K. Oberle, A. Diefenbach

78. Analysis of CD28 inhorses and applicationof a polyclonal Ab to in-duce co-stimulationS. Ibrahim, E. Abd El-Gawad, F. Steinbach

47. 2D-DIGE analysis ofenriched secretory lyso-somes of human T andNK cellsH. Schmidt, C. Gelhaus,M. Lettau, M. Nebendahl, M. Leippe, O. Janssen

55. Vaccination withMHC class II-heterolo-gous dendritic cells in-duces protectiveimmunity against Leish-mania majorK. A. Remer, H. Moll

63. Post-transcriptionalregulation of FasL ex-pression: Molecular in-sights into storage,activation-induced mo-bilization and sheddingof a prototypic deathfactorM. Lettau, O. Janssen

71. Specificity of interac-tion between killer cellimmunoglobulin-like re-ceptors (KIR) and MHCclass I molecules of therhesus macaque(Macaca mulatta)P. Kruse, C. Rosner, M. Hermes, L. Walter

79. Species-specificgeneration of immuneregulatory molecules byhost pathogen coevolu-tionR. Kammerer, T. Popp,S. Haertle, B. B. Singer,E. Travanty, Z. Qian, K. V. Holmes, W. Zimmermann

15.30-


14Scientific Programme – Thursday, September 4, 2008


16.45-

18.00

Parallel Symposium 2:VaccinationChair: M. Müller, H.J. Schild

Parallel Symposium 2:In Vivo ImagingChair: C. Scheinecker, C. Berek

Parallel Symposium 2:ImmunomodulationChair: W. Ellmeier, E. Schmitt

Delineation of plasmablast characteristicsgenerated in steady-state and in systemicimmune responsesH. Mei

The In Situ Dynamics of Innate and Adap-tive Immune Cell Behaviour Revealed ByIntravital Multiphotometry MicroscopyR. Germain

Probing Dendritic cell In vivo FunctionsS. Jung

Towards a coronavirus- based multigenevaccine platformB. Ludewig

In vivo imaging of Germinal Center B CellsA.E. Hauser

Tec kinases in T cell activation and functionL. Berg

Modulating Vaccine Responses with Innate ImmunityB. Pulendran

Non-invasive imaging of inflammation -the quest for specificityA. Wunder

Inducible Foxp3-dependent or -indepen-dent human CD4+ regulatory T Cells.R. Bacchetta

19.00 Welcome Reception at the Vienna City Hall

For more information, please contact us at:Call: +49 (0) 9761/ 406-0 • +31 (0) 43 40 77 310E-mail: [email protected] • [email protected] [email protected]

NUDIST COLONIES.CD-1-nude • NMRI-nude • BALB/c-nude

We’ve improved the availability of our nude mouse strains.

15Scientific Programme – Friday, September 5, 2008


08.15-

09.30

Parallel Symposium 1:Innate Immunity: RegulationChair: M. Säemann, W. Solbach

Parallel Symposium 1:Mucosal InflammationChair: B. Bohle, D. Männel

Parallel Symposium 1:TransplantationChair: T. Wekerle, R. Schmidt

Innate resistance, inflammation, and cancerG. Trinchieri

Role of epithelial barrier function in allergyP. Brandtzaeg

Antibody-mediated transplant rejectionG. Böhmig

Interferon regulatory factors and innate immunity in early lifeM. Goldman

A prominent role for mucosal cystine/cys-teine metabolism in intestinal immunoreg-ulationS. Meuer

Immune monitoring and therapy in trans-plantation - from bench-to -bedsideH.D. Volk

The mammalian target of rapamycin andinnate immunityT. Weichhart

Tumor Necrosis Factor and the conse-quences of its ablation in vivoS. Nedospasov

Tolerance through mixed chimerism: howclose to clinical application is it?T. Wekerle

09.30-




10.30-

12.15

Allergy IChair: H. Renz, F. Horak

Regulatory Lympho-cytes IChair: L. Klein, T. Wekerle

Alloimmunity & Toler-anceChair: B. Arnold, H. Ankersmit

Pattern RecognitionReceptors & MyeloidCellsChair: S. Bauer, C. Bogdan

Innate Immunity: RegulationChair: M. Zeyda, K. Pfeffer

80. Tracing antigen sig-natures in the human IgE repertoireK. Marth, M. Novatchkova, M. Focke-Tejkl, S. Jenisch, S. Jäger, D. Kabelitz, R. Valenta

88. Analyses of a novelregulatory T cell subsetin patients with SystemicLupus Erythematosus(SLE)M. Bonelli, A. Savitskaya, E. Feierl,S. S. Smolen, C. Scheinecker

96. Role of IL-2 in induc-tion of CD8 T cell toler-ance by LSECA. K. Schurich, M. Berg,A. Limmer, H. J. Schild,L. Diehl, P. A. Knolle

104. Influence of viral in-fection on recognition ofself RNAT. von Thülen, M. Nain,S. Bauer

112. Suppression ofadaptive immune re-sponses by Toll-like re-ceptor ligandsB. Schumak, M. Brock,F. Jüngerkes, G. Hartmann, T. Tüting,P. Knolle, R. Zawatzky, S. Bauer, A. Limmer

81. Stable dust chal-lenge inhibits allergic air-way reactivity throughTLRs 2, 3, 4, 7, 9 and/orother PRRs/TLRsR. Ferstl, S. Spiller, S. Dreher, H. Garn, H. Fehrenbach, E. Von Mutius, H. Renz,H. Wagner, C. J. Kirschning

89. CD4+ CD25high regu-latory T cells suppress Thelper 1 but not T helper2 cytokinesT. Bollinger, A. Bollinger, W. Solbach

97. Proliferation of CD8-positive T cells in the Lu-mina of Rat RenalAllograft Blood VesselsV. Grau, G. Fuchs-Moll,W. Padberg

105. TLR7-dependentrecognition of transferRNAY. Zhao, A. Kaufmann, K. Steinbach, S. Bauer

113. The cytoplasmic tailof CD45 is released fromactivated phagocytesand can act as an in-hibitory messenger for T cellsS. Kirchberger, O. Majdic, S. Blüml, C. Schrauf, J. Leitner, C. Gerner, W. Paster, N. Gundacker, M. Sibilia,J. Stöckl

82. Composition of Bcell receptor classic anti-gen-binding site regu-lates allergic airwayinflammation in a murinemodel of experimentalasthmaS. Kerzel, J. Wagner, T. Rogosch, A. Yildirim, H. Fehrenbach, H. Garn,R. F. Maier, H. W. Schroeder Jr., M. Zemlin

90. Induction of CD25-

Foxp3- regulatory T cellsby chronic antigen stim-ulation in vivoW. Hansen, A. M. Westendorf, J. Buer

98. Dickkopf 3, a novelmodulator of T cell re-sponsesM. Papatriantafyllou,G. Moldenhauer, H. J. Gröne, C. Niehrs,G. J. Hämmerling, T. Oelert, B. Arnold

106. Intrabody mediatedretention of TLR2 andTLR9 in the ER to inhibitchronic inflammationT. Böldicke, S. Dreher,S. Somplatzki, L. Grosse-Hovest, B. Maaß, W. Lindenmaier, H. Wagner, C. Kirschning

114. Molecular mecha-nisms of Staphylococcusaureus-induced au-tophagyK. Sabel, D. Grumme, S. A. Leggio, A. Schnaith, M. Krönke,O. Krut

83. High expression ofinflammatory cytokines,chemokines and their re-ceptors in lungs of miceduring allergic asthmaremission underlies thepersistence of chroniclung inflammationR. Bankoti, L. El-Housseiny, G. Dekan, O. Hoffmann,G. Stingl, M. M. Epstein

91. Transfer of in vitroexpanded humanCD45RA+CD4+CD25high regulatory T cells in-hibits early expansion ofconventional T cells inimmunodeficient Rag2-/-c-/- miceT. J. Boeld, J. Albrecht,K. Doser, R. Eder, J. Stahl,E. Typlt, E. Obermann, R. Andreesen, P. Hoffmann, M. Edinger

99. Toag-1 enables pre-diction of CMV mediatedtransplant tolerance ab-rogationW. Gong, M. Klöpfel, K. Vogt, S. Haase, A. Reutzel-Selke, H. Volk, A. Pascher, B. Sawitzki

107. Analysis of Toll-likereceptor 7 and Toll-likereceptor 9 chimeric mol-eculesJ. Willemsen, P. Yu, S. Bauer

115. 12/15-lipoxygenaseis involved in the limita-tion of inflammation andtissue damage in murinearthritisG. Krönke, J. Katzenbeisser, S. Uderhardt, W. Baum,R. Axmann, J. Zwerina,G. Schett

84. Antigen -specific im-munotherapy inhibitedTh2 via GATA-3 andTh17 cells in an allergicasthma model.N. Zhivkova, R. Karwot,J. H. Maxeiner, P. Scholtes, K. Soo, S. Finotto

92. Long-term vaccina-tion efficiency is inde-pendent of regulatory TcellsG. Gasteiger, W. Kastenmuller, L. Stross, D. H. Busch, T. Sparwasser, I. Drexler

100. Mutated CYLD af-fects the functional stateof dendritic cellsM. Bros, N. Wiechmann,V. Besche, N. Hövelmeyer, S. Reissig, S. Grabbe, A. Waisman,A. B. Reske-Kunz

108. The divergent roleof the mammalian targetof rapamycin (mTOR) indendritic cells subtypesM. Haidinger, T. Weichhart, M. Poglitsch, M. Hecking,M. Zeyda, R. Geyeregger,J. Werzowa, W. H. Hörl,M. D. Säemann

116. Promoter methyla-tion status is changedwith altered DEFB1 geneexpression in COPDE. Andresen, J. Bullwinkel, C. Lange,H. Heine

85. Selective depletionof Foxp3+ cells inDEREG mice allowsfunctional analysis ofregulatory T cells duringexperimental allergic air-way inflammationA. Hartl, K. Lahl, H. Hamad, A. Ö. Yildirim,H. Fehrenbach, R. Teich,H. Garn, H. Renz, B. Lambrecht, T. Sparwasser

93. Retrovirally trans-duced, antigen-specificT cells for therapy oftype 1 diabetesN. Mpofu, N. Saal, M. Hardtke-Wolenski, M. P. Manns, E. Jaeckel

101. Enhanced nuclearexport of NFATc1 andimpaired translocation ofNFATc2 is observed inanergic iTreg generatedby tolerogenic DCH. S. Adler, R. Orth, K. Streck, E. Graulich, K. Steinbrink

109. Mammalian targetof rapamycin (mTOR) or-chestrates the defenseprogram of innate im-mune cellsF. Schmitz, A. Heit, S. Dreher, K. Tittel, J. Mages, T. Haas, A. Krug, K. Janssen, C. V. Kirschning, H. Wagner

117. Macrophage phos-phoproteome dynamicsafter LPS-stimulationand its shaping by theMAPK-PhosphataseDUSP1: a SILAC-basedapproachG. Weintz, J. Olsen, J. Mages, M. Mann, R. Lang

17Scientific Programme – Friday, September 5, 2008 (continued)


86. Molecular and func-tional analysis of theantigen receptor of Bet v1-specific helper T lym-phocytesA. Neunkirchner, V. M. Leb, K. G. Schmetterer, H. J. Kueng, D. Haiderer,S. Mutschlechner, B. Bohle, W. F. Pickl

94. BAC-transgenic micefor depletion of Foxp3+

regulatory T cells:Homeostatic expansionof TregsJ. Suffner, K. Hochweller, N. Garbi,G. Hämmerling

102. Allogeneic dispari-ties in the surface mole-cule immunoglobulin-liketranscript 5 (ILT-5) in-duce potent antibody re-sponses in stem celltransplanted patientsK. Pfistershammer,, A. Lawitschka, J. Leitner,C. Klauser, R. Weigl, G. Böhmig, G. F. Fischer,M. Heemskerk, O. Majdic, W. F. Pickl, H. Greinix, P. Steinberger

110. Hsp60 modulatesneutrophil functionsA. Osterloh, M. Piedavent, F. Geisinger, B. Fleischer, N. Brattig,M. Breloer

118. Prophylactic block-ade of TLR4 or thera-peutic blockade of bothTLR2 and TLR4 protectsmice from Gram-nega-tive infection and subse-quent antibiotic therapyinduced fatal septicshockC. J. Kirschning, G. Elson, R. Ferstl, S. Dreher, T. Müller, M. Freudenberg, B. Daubeuf, H. Wagner,S. Spiller

87. Cloning, expressionand mapping of aller-genic determinants of alphaS1-casein, a majorcow’s milk allergenU. Schulmeister, H. Hochwallner, I. Swoboda, M. Focke-Tejkl, M. Nystrand, A. Harlin, J. Thalhamer,S. Scheiblhofer, W. Keller,B. Niggemann, S. Quirce,C. Ebner, A. Mari, G. Pauli, B. Geller, U. Herz, R. Valenta, S. Spitzauer

95. Lack of Foxp3 Treg-linage marker expressionin mouse epithelial cellsC. T. Mayer, K. Lahl, C. Loddenkemper, T. D. Sparwasser

103. Dendritic cell-acti-vated, endothelial cell-specific CTL recognizinga minor histocompatibil-ity antigen rapidly inducetransplant vasculopathyB. B. Bolinger, D. Engeler, P. Krebs, S. Miller, B. Ludewig, M. Hoffmann, P. Clavien,Y. Tian

111. Spatial separationof cross-presentationand endogenous antigenpresentationS. Burgdorf, C. Schölz,A. Kautz, R. Tampé, C. Kurts

119. Biological charac-terization of mouse betadefensin 14 - an ortho-logue of human beta defensin 3J. Röhrl, T. Hehlgans

Time Lecture Hall 2

12.15-

13.45

Satellite Lunch Symposium - OctapharmaImmune modulation with intravenous immunoglobulin: the established and the advancesChair: S. Meuer

Immunthrombocytopenia as the first model for biological treatment with IVIG in chronic inflammatory and autoimmune diseasesP. Imbach

Intravenous Immunoglobulins: mechanisms of action and options for improvement of therapeutic efficacyF. Nimmerjahn

Basic research in human immunology creates new therapeutic optionsS. Meuer

Discussion and wrap-up

Time Lecture Hall 1

13.00-

13.45

Drittmittelförderung der DFG: Kriterien für eine erfolgreiche AntragstellungChair: Y. SamstagA. Strecker



14.00-

15.30

Infection IChair: F. Schmitz, S. Ehlers

Allergy IIChair: B. Linhart, G. Stary

Regulatory Lympho-cytes IIChair: A. Rosenkranz, H. Schulze-Koops

Mucosal ImmunityChair: R. Förster, M. Pasparakis

B-LymphocytesChair: V. Sexl, T. Winkler

120. Restricted B cell re-ceptor diversity convertsacute into chronic viralinfectionA. Bergthaler, L. Flatz,A. Verschoor, A. N. Hegazy, E. Horvath, M. Holdener,K. Fink, B. Odermatt, D. D. Pinschewer

128. HLA-classII/pep-tide-TCR interactions ofthe single immunodomi-nant T cell epitope of Artv 1, the major mugwortpollen allergenB. Jahn-Schmid, B. Maillere, V. Leb, W. Pickl, G. Gadermaier,F. Ferreira, B. Bohle

136. Generation of in-duced CD8+Foxp3+ reg-ulatory T cells in vitroC. Mayer, K. Lahl, D. Dittlein, V. Wenzel, O. Gassner, J. Stephani,C. Loddenkemper, T. Sparwasser

144. Role of the tran-scription factor PU.1 inhuman lamina propriamacrophagesF. A. Lasitschka, A. Heidtmann, T. Giese,G. Wabnitz, A. Schrödter, J. Winter,A. Ulrich, S. C. Meuer, J. Schröder-Braunstein

152. Swiprosin 1 - posi-tive regulator of BCR in-duced calcium fluxC. Kroczek, C. Lang, A. Avramidou, L. Nitschke, A. Elter, H. M. Jäck, D. Mielenz

121. Interleukin 18 is es-sential for protective im-munity against M.tuberculosis.B. Schneider, D. Korbel, K. Hagens, M. Koch, S. H. Kaufmann, H. Mittruecker, U. E. Schaible

129. Proteomic analysisand mass-spectrometricidentification of differen-tially regulated proteinsin primary human ker-atinocytes by allergensS. Ohnesorge, L. Dietz,P. Pankert, M. Schnoelzer, H. Thierse

137. CD8+CD38+ T-cells:A competent regulatoryT-cell populationA. Bollinger, H. Fehrenbach, T. Bollinger, T. Bollinger,Z. Orinska, S. Bulfone-Paus

145. Role of eosinophilsin TGF-beta expressionin human intestineF. Ulmer, S. C. Bischoff,A. Lorentz

153. Engagement ofCD83 on B cells aug-ments IgG1 response invivoB. Kretschmer, K. Lüthje, S. Schneider, B. Fleischer, M. Breloer

122. Wnt/Frizzled signal-ing in infectious dis-eases: Deciphering therole of FZD1 in my-cobacterial infectionsN. Reiling, T. Endermann, S. Ehlers,J. Neumann

130. Immunosuppres-sion and allergy in organtransplant recipients: ev-idence for insufficientcontrol of allergen spe-cific responsesT. Eiwegger, S. Gruber,C. Geiger, E. Dehlink, T. Frischer, P. Jaksch, W. Klepetko, Z. Szépfalusi

138. Tolerogenic poten-tial of lentivirally trans-duced murine DCoverexpressing antiin-flammatory moleculesV. Besche, N. Wiechmann, S. Trojandt, S. Grabbe,A. B. Reske-Kunz, M. Bros

146. CD4+ Foxp3+ regu-latory T cell expansioninduced by antigen-dri-ven interaction with in-testinal epithelial cellsindependent of localdendritic cellsA. M. Westendorf, D. Fleissner, S. Jung, A. D. Gruber, W. Hansen,J. Buer

154. The analysis of in-travital two-photon im-aging of germinalcentres implies a novellymphocyte migrationand affinity maturationmodelM. Meyer-Hermann, M. Figge

123. Cavity formation intuberculosis is mediatedby interleukin-4 recep-tor-alpha-dependentmechanismsL. Heitmann, T. Schreiber, T. Thye, A. N. McKenzie, A. Cutler, F. Brombacher,R. D. Horstmann, C. G. Meyer, S. Ehlers,C. Hoelscher

131. Long-term toler-ance in IgE-mediated al-lergy through molecularhematopoieticchimerism in a murinemodelU. Baranyi, B. Linhart,N. Pilat, M. Gattringer, C. Klaus, E. Schwaiger,F. Muehlbacher, J. Iacomini, R. Valenta, T. Wekerle

139. IL-27 inhibits thedevelopment of regula-tory T cells via STAT3M. Huber, V. Steinwald,A. Guralnik, A. Brüstle, P. Kleemann, C. Rosenplänter, T. Decker, M. Lohoff

147. Split tolerance afteroral vaccination of micewith recombinant Es-cherichia coli Nissle1917 expressing fimbrialadhesin K88K. A. Remer, M. Bartrow, H. Moll, T. A. Oelschläger

155. Proapoptotic BH3-only proteins Bim andPuma are essential forapoptosis of germinalcenter-derived memoryB cells and antibody-forming cellsS. Fischer,, D. Tarlinton,A. Strasser

124. Immunological inhi-bition of gC1qR/p33, areceptor for C1q, de-creases adherence ofStaphylococcus aureusto microvascular en-dotheliumS. Sethi, M. W. Laschke,J. Roller, L. von Mueller,E. Peerschke, B. Ghebrehiwet, I. Bajric,M. D. Menger, M. Herrmann

132. Generation of anIgE knock-in mouse andits use in systemic ana-phylaxis in vivoP. Yu, W. Lübben, S. Bauer

140. Development of“would-be” regulatory Tcells and defective con-trol of Th2-cytokine pro-duction in natural scurfymutant miceK. I. Lahl, C. T. Mayer, J. Huehn, C. Lodden-kemper, G. Eberl, J. Buer, T. Sparwasser

148. The role of IL-23/IL-17 in Toxoplasma gondiiinduced small intestinalimmunopatologyM. L. Munoz-Roldan, D. Struck, M. Heimesaat,C. Hoelscher, U. Mueller,Y. Iwakura, N. Ghilardi,O. Liesenfeld

156. Identification of achemokine receptor pro-file characteristic for me-diastinal large B-celllymphomaU. E. Höpken, I. Anagnostopoulos, M. Broemer, C. Scheidereit, K. Joehrens, M. Hübler,H. Stein, M. Lipp, B. Dörken, A. Rehm

125. The fibrin-derivedpeptide B 15-42 (FX06)for treatment of capillaryleakM. Gröger, W. Pasteiner,G. Ignatyev, U. Matt, S. Knapp, P. Friedl, D. Zinkl, K. Zacharowski,R. Hofer-Warbinek, P. Petzelbauer, S. Reingruber

133. Murine plasma andnon-plasma B cells ex-press different IgE reper-toiresT. Rogosch, S. Kerzel, L. Sikula, R. Maier, M. Zemlin

141. TLR2 ligands act directly on Treg to abro-gate suppression ofCD4+CD25- T cellsH. Oberg, M. Juricke, S. Ussat, H. Ly, D. Kabelitz, D. Wesch

149. The mesentericlymph node regulatesthe amplitude of IgA secretion in the drainedarea: potential role of thespleen in the immune response against orallyapplied cholera toxinA. Hahn, N. Thiessen, R. Pabst, M. Ahrendt, U. Bode

157. The adapter proteinSLy2 represents a newlyidentified regulator of cy-toskeletal rearrange-mentsM. L. von Holleben

19Scientific Programme – Friday, September 5, 2008 (continued)

Time Lecture Hall 2

18.00-

19.30

General Assembly DGfIChair: S. Meuer


175. Immunopathologi-cal basis of lymphocyticchoriomeningitis virus-induced chorioretinitisand keratitisM. Zinkernagel, P. Krebs,B. Bolinger, S. Miller, B. Ludewig

134. Induced ablation ofmast cells in adult mice:Slow recovery of mastcell populations in thetissues.J. Scholten, A. Gerbaulet, B. Hiller,W. Muller, T. Krieg, T. Buch, A. Waisman, K. Hartmann, A. Roers

142. Influence ofCD4+CD25+ regulatoryT cells on thetransendothelial migra-tion of CD4+CD25- TcellsT. Bedke, M. Kretz, K. Mahnke, A. H. Enk

150. The role of CXCR5in antigen-independentdevelopment and anti-gen-dependent matura-tion of nose-associatedlymphoid tissue (NALT)J. Krege, S. Seth, S. Hardtke, A. MarquesDavalos-Misslitz, R. Förster

158. Antigen receptor tailclue of class-switchedmemory B cellsN. Engels, C. Heemann,L. König, T. Tsubata, S. Griep, V. Schrader, J. Wienands

127. CD8 T cell-medi-ated immune responsesagainst cross-presentingliver sinusoidal endothe-lial cells leads to hepati-tisD. Stabenow, K. Gärtner, M. Svorcova,M. Odenthal, H. Dienes,U. Protzer, P. A. Knolle

135. Timothy grasspollen major allergen Phlp 1 - a protease?K. Röschmann, P. König, A. J. Ulmer, A. Petersen

143. Expansion of im-mune-suppressiveV 9V 2 T cells as a novelregulatory mechanism ofIL-12 secreting dendriticcellsM. W. Traxlmayr, A. M. Dohnal, D. Wesch,D. Kabelitz, T. Felzmann

151. T cell-specific dele-tion of gp130 rendersthe highly susceptible In-terleukin-10 deficientmouse mutant resistantto intestinal nematodeinfectionN. Fasnacht, M. C. Greweling, M. Bollati-Fogolin,, A. Schippers,, W. Müller,

159. Role of basophils inimmunological memoryresponsesA. J. Denzel, U. Maus,M. Rodriguez Gomez, M. Niedermeier, Y. Talke,N. Göbel, M. Mack

15.30-



16.45-

18.00

Parallel Symposium 2:InfectionChair: S. Knapp, I. Förster

Parallel Symposium 2:Adaptive Immunity: RegulationChair: H. Stockinger, L. Klein

Parallel Symposium 2:Adaptive Immunity: B-CellsChair: G. Zlabinger, H-M. Jäck

Origin of CD8+ effector and memory T cellsubsetsD.H. Busch

Innate and adaptive IL-17 in the control ofimmune responsesB. Stockinger

Transcriptional control of B cell develop-mentM. Busslinger

Mutual host pathogen reactions in tuber-culosisU. Schaible

Autoregulatory circuits in inflammatory T cell responsesA. Scheffold

Memory B cell sub-populationsJ.C. Weill

Innate immune response to pneumococcalpneumoniaS. Knapp

Innate Immunity in regulation of antibodymediated inflammationR.E. Schmidt

Plasma cell memoryA. Radbruch

19.30 Departure with buses to the Viennese “Heuriger” Fuhrgassl-Huber

20Scientific Programme – Saturday, September 6, 2008


08.45-

10.00

Parallel Symposium 1:AutoimmunityChair: J. Smolen, H. Schulze-Koops

Parallel Symposium 1:InflammationChair: J. Stöckl, K. Pfeffer

Parallel Symposium 1:AllergyChair: R. Valenta, J. Kalden

The life history of an autoimmune drivercloneE. Sercarz

Mechanisms of inflammatory bone destructionK. Redlich

Human Th17 cellsS. Romagnani

Immunopathogenesis of rheumatoid arthri-tis: induction of arthritogenic autoimmunereactions by proinflammatory stimuliG. Steiner

Novel cytokines in inflammatory diseasesF. Liew

New facets in mast cell activationS. Bulfone-Paus

Modeling multiple sclerosis: autoimmune T and B cells in the pathogenesis of thebrain inflammatory diseaseH. Wekerle

IL-17 and kynurenines in pathogenic inflammationL. Romani

From allergens to vaccinesR. Valenta

10.00-

10.30Coffee Break / Exhibition

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Time Lecture Hall 2 Lecture Hall 3 Lecture Hall 4 Lecture Hall 5

10.30-

12.15

Autoimmunity IIChair: R. Schwinzer, G. Staffler

Infection IIChair: V. Leksa, O. Sharif

Complement SystemChair: M. Kirschfink, M. Wahrmann

Cytokines, Chemokines &their receptorsChair: U. Höpken, M. Sibilia

160. CCR7 is essential for reg-ulatory T cell function in anti-GBM glomerulonephritisK. Hochegger, A. Rosenkranz,A. Rot

168. Immunemodulation bySiglec-E during Trypanosomacruzi infectionH. Erdmann, P. R. Crocker, B. Fleischer, T. Jacobs

176. Human factor H-relatedprotein 4 (CFHR4) recruits C-reactive protein to the surfaceof necrotic cellsM. Mihlan, M. Hebecker, M. Huber-Lang, R. Dahse, P. F. Zipfel, M. Józsi

183. gp130 onmacrophages/neutrophils neg-atively regulates Th17 develop-ment during experimentaltuberculosisJ. Sodenkamp, I. Foerster, W. Mueller, C. Hoelscher

161. The nuclear receptorPPARgamma serves as an in-trinsic regulator of Th17 cell dif-ferentiationL. Klotz,, I. Dani, S. Burgdorf,A. Waisman, G. Eberl, J. Alferink, B. Langhans, T. Klockgether, P. Knolle

169. A novel Leishmania majoramastigote culture systemU. A. Wenzel, S. Möller, M. Klinger, S. Liebau, T. Laskay,G. van Zandbergen

177. Regulation of mouse fi-colin-B expression in immunecompetent cellsV. L. Runza, J. Kürchner, D. Weber-Steffens, D. N. Männel

184. The role of optineurin(FIP2) in adenovirus E3-14.7K-mediated inhibition of TNFR1apoptosisL. Klingseisen, G. Knoll, W. Schneider-Brachert

162. Spontaneous CD8+ T CellMediated Liver Inflammation ina Transgenic Mouse Model ofAutoimmune HepatitisM. Zierden, E. Kühnen, M. Odenthal, H. P. Dienes

170. The elimination ofAnaplasma phagocytophilum invivo requires CD4+ T cells, butis independent of Th1 cy-tokines and a wide spectrum ofeffector mechanismsK. Birkner, Y. Kern, B. Steiner,C. Bogdan, F. D. von Loewenich

178. Functional analyses indi-cate pathogenic role of factor H autoantibodies in atypicalhemolytic uremic syndromeS. Strobel, P. F. Hoyer, C. J. Mache, E. Sulyok, P. F. Zipfel, M. Józsi

185. Overlapping functions ofIL-7 and TSLP in lymphoid de-velopmentD. Finke, L. Flueck, A. G. Farr,A. G. Rolink, S. Chappaz

163. Peripheral T cells are thetherapeutic targets of high-dose glucocorticoids in experi-mental autoimmuneencephalomyelitisS. Wüst, J. van den Brandt, J. P. Tuckermann, R. Gold, H. M. Reichardt, F. Lühder

171. Oxidized phospholipids in-hibit phagocytosis via a PKAdependent mechanismU. Matt, O. Sharif, T. Furtner, K. Stich, A. Zivkovic, S. Knapp

179. A dual role of the C5a re-ceptor (C5aR) in acute andchronic dextran sulphate in-duced models of inflammatorybowel diseaseK. Johswich, M. Martin, A. Bleich, M. Kracht, O. Dittrich-Breiholz, E. Gessner,S. Suerbaum, C. Rheinheimer,A. Klos

186. Organ-specific suppres-sion of CCL17 productionthrough Interferon-T. Globisch, S. Stutte, V. Lukacs-Kornek, C. Kurts, I. Förster

164. The proteasome inhibitorbortezomib depletes plasmacells and protects lupus micefrom nephritisK. Neubert, S. Meister, K. Moser, F. Weisel, D. Maseda,K. Amann, T. H. Winkler, J. R. Kalden, R. E. Voll

172. Control of Persistent HBVInfection by Hepatitis B CoreAntigen-activated NK cells: A Possible Mechanism for theHBV PersistenceL. Huang, P. Chen, P. Knolle

180. Candida albicans CaHGT1and its role in complement inhi-bition and modulation of othervirulence factorsI. Lesiak, G. Vogl, T. Schwarzmüller, M. P. Dierich,K. Kuchler, R. Würzner

187. Down-regulation of IFN-during HPV-induced carcino-genesisB. Rincon-Orozco, F. Rösl

165. CD8 T cells specific for aglomerular antigen induce renalinflammation in a CD4 help de-pendent fashion and maycause progressing Glomeru-lonephritisF. Heymann, E. E. Hamilton-Williams, I. Ludwig-Portugall, S. Quaggin, J. Flöge, H. Gröne,C. Kurts

173. Acute infection with a sin-gle hepatitis C virus strain indialysis patients: analysis ofadaptive immune response andits impact on viral sequenceevolutionL. Weseslindtner, C. Neumann-Haefelin, S. Viazov,A. Haberstroh, J. Kletzmayr, J. H. Aberle, J. Timm, S. R. Ross, R. Klauser-Braun, T. F. Baumert, M. Roggendorf, R. Thimme, H. Holzmann

P419. Characterization of factorH binding to neutrophil granu-locytesJ. Losse, P.F. Zipfel, M. Józsi

188. An IFN reporter mousemodel for the visualization ofthe initiation of the Type I inter-feron response in vivoP. Dresing, S. Scheu, R. M. Locksley

166. A new model for inflam-matory bowel disease: A trans-genic mouse expressing acrossreactive T cell receptorrecognizing murine and bacter-ial HSP60N. Schmidt, T. Joeris, U. Steinhoff

174. Type I Interferons as viru-lence-determining factors inListeria monocytogenes infec-tionsB. Reutterer, S. Stockinger, A. Pilz, D. Soulat, R. Kastner, S. Westermayer, T. Rülicke, M. Müller, T. Decker

182. Rituximab-induced ADCCof tumour cells is variably modified by complement iC3bA. Dörr, C. Watzl, M. Kirschfink

189. Chemokine receptor CCR7contributes to a rapid and effi-cient clearance of lytic MHV-68from the lung while bronchus-associated lymphoid tissue har-bors virus during latencyJ. R. Kocks, H. Adler, H. Danzer, K. Hoffmann, D. Jonigk, U. Lehmann, R. Förster

167. NAADP/Ca2+ signaling: anew therapeutic target for T cellmediated autoimmune diseaseF. Odoardi, C. Cordiglieri, W. Dammermann, B. Zhang, M. Hohenegger, B. V. Potter, A. Guse, A. Flügel

126. Yersinia enterocolitica dif-ferently affects DC subpopula-tions in vivoS. E. Autenrieth, T. Linzer, P. Warnke, S. Schmitz, I. B. Autenrieth

190. IL-27 acts as a PrimingSignal on Human Keratinocytesand Antigen- Presenting CellsJ. Zeitvogel, T. Werfel, M. Wittmann

Venue

International Congress Center Berlin (ICC Berlin)

Neue Kantstraße / Ecke Messedamm

14057 Berlin, Germany

www.icc-berlin.de

Under the auspices of EFIS

Congress President

Prof. Dr. med. Reinhold E. Schmidt

Medizinische Hochschule Hannover

Klinik für Immunologie und Rheumatologie

Carl-Neuberg-Straße 1

30625 Hannover, Germany

Phone: +49 (0)511– 532-6656

Fax: +49 (0)511– 532-9067

E-Mail: [email protected]

Congress Secretariat

K.I.T. GmbH Association & Conference

Management Group & Co. KG

Kurfürstendamm 71

10709 Berlin, Germany

Phone: +49 (0)30 – 246 03-0

Fax: +49 (0)30 – 246 03-200

E-Mail: [email protected]

www.kit-group.org

2nd European Congress of Immunology

www.eci-berlin2009.com

September 13 – 16, 2009Berlin, Germany

Immunity for LifeImmunology for Health

8575_kit_eci09_anzA4_bl.indd 1 04.08.2008 11:27:59 Uhr


Time Lecture Hall 1

10.30-

12.45

Satellite Lunch Symposium - PhadiaVom rekombinanten Allergen zu neuen AllergietherapienChair: R. Valenta, N. Reider

Rekombinante Allergene: Vom Beginn zur GegenwartH. Breiteneder

Rekombinante NahrungsmittelallergeneK. Hoffmann-Sommergruber

Klinische Anwendungen für rekombinante AllergeneP. Schmid-Grendelmeier

Klinische Erfahrungen mit AllergenchipsJ. M. Baron

Die Komplexitaet von zellulären Allergietesten J. Kleine-Tebbe

Immuntherapie und Verlaufkontrolle mit rekombinanten AllergenenG. Pauli

12.45-

13.00Pause (mit Snack)

Time Lecture Hall 1

13.00-

13.45

Klinische Fälle aus der Allergologie: Wie hätten Sie entschieden?Chair: Z. Szepfalusi, G. Pauli

Werner Aberer, Reinhart Jarisch, Felix Wantke und Stefan Wöhrl präsentieren klinische Fälle aus der Allergologie

14.00-

14.30

Best Poster AwardsChair: J. Smolen, S. Meuer

Time Lecture Hall 2

15.00 General Assembly ÖGAIChair: J. Smolen, M. Säemann

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Siemens Healthcare Diagnostics. Das Engagement, um Ihrenindividuellen Bedürfnissen auf den Grund zu gehen.

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Poster Viewing 25

Thursday, September 4, 2008

09.30 – 10.30 hrs

T-Lymphocytes IChair: B. Jahn-Schmid, C. ScheineckerP001 – P028

T-Lymphocytes IIChair: W. Pickl, H. StockingerP029 – P056

Innate Immunity: Antigen-Presenting CellsChair: T. Weichhart, M. GillietP057 - P075

Signal TransductionChair: L.J. Berg, W. EllmeierP076 - P094

Tumor ImmunologyChair: O.J. Finn, T. BlankensteinP095 - P117

Thursday, September 4, 2008

15.30 – 16.30 hrs

Innate Immunity: RegulationChair: M. Zeyda, S. BeissertP118 - P134

Pattern Recognition Receptors & Myeloid CellsChair: F. Schmitz, J. StöcklP135 - P151

NK CellsChair: C. Watzl, V. SexlP152 - P164

Vaccines & AdjuvantsChair: H. Lassmann, T. WeichhartP165 - P187

ImmunomodulationChair: M. Fischer, G. ZlabingerP188 - P208

Friday, September 5, 2008

09.30 – 10.30 hrs

Alloimmunity & ToleranceChair: G. Böhmig, M. SäemannP209 - P233

AllergyChair: B. Bohle, S. Bulfone-PausP234 - P264

InfectionChair: U. Schaible, S. KnappP265 - P296

Mucosal ImmunityChair: S. Meuer, P. BrandtzaegP297 - P308

Friday, September 5, 2008

15.30 – 16.30 hrs

Autoimmunity IChair: R. Germain, E. SercarzP309 - P329

Autoimmunity IIChair: G. Steiner, J. KaldenP330 - P352

Complement System and B-LymphocytesChair: F. Melchers, A. RadbruchP420 and P353 - P360

Regulatory LymphocytesChair: L. Klein, R. BacchettaP361 - P383

Cytokines, Chemokines & their receptorsChair: F.Y. Liew, L. RomaniP384 - P404

Veterinary ImmunologyChair: B. Kaspers, A. SaalmüllerP405 - P418

Business MeetingsAs per date of printing

Closed Business Meetings

Wednesday, September 3, 200810.00 – 12.00 hrs Steering Committee Meeting ECI 2009 Lecture Room 25 / Level 812.00 – 14.30 hrs Vorstandssitzung DGfI Hotel Regina – Salon Makart

Thursday, September 4, 200811.00 – 13.00 hrs Promotion Committee Meeting des ECI 2009 Lecture Room 25 / Level 812.30 – 14.00 hrs Sitzung der DGfI Kommission “Fachimmunologe” Lecture Room 13 / Level 7

Friday, September 5, 200812.00 – 14.00 hrs Arbeitskreise der DGfI Lecture Room 25 / Level 8

Saturday, September 6, 200809.00 – 11.00 hrs DGfI Educational Committee Lecture Room 25 / Level 8

26

Satellite Lunch Symposia

Thursday, September 4, 2008, 12.15 – 13.45 hrs, Lecture Hall 1

B cell: Promising target in autoimmune diseasesChair: J. Smolen

The biology of the B cell in autoimmune diseasesA. Radbruch

Clinical experiences with B cell therapiesT. Dörner

Safety: Experiences with RituximabH-P. Brezinsek

Friday, September 5, 2008, 12.15 – 13.45 hrs, Lecture Hall 2

Immune modulation with intravenous immunoglobulin: the established and the advancesChair: S. Meuer

IntroductionS. Meuer

Immunthrombocytopenia as the first model for biological treatment with IVIG in chronic inflammatory and autoimmune diseasesP. Imbach

Intravenous Immunoglobulins: mechanisms of action and options for improvement of therapeutic efficacyF. Nimmerjahn

Basic research in human immunology creates new therapeutic optionsS. Meuer

Discussion and wrap-up

Saturday, September 6, 2008, 10.30 – 12.45 hrs, Lecture Hall 1

Vom rekombinanten Allergen zu neuen AllergietherapienChairs: R. Valenta, N. Reider

Rekombinante Allergene: Vom Beginn zur GegenwartH. Breiteneder

Rekombinante NahrungsmittelallergeneK. Hoffmann-Sommergruber

Klinische Anwendungen für rekombinante AllergeneP. Schmid-Grendelmeier

Klinische Erfahrungen mit AllergenchipsJ.M. Baron

Die Komplexitaet von zellulaeren AllergietestenJ. Kleine-Tebbe

Immuntherapie und Verlaufkontrolle mit rekombinanten AllergenenG. Pauli

12.45 - 13.00 Pause (mit Snack)

13.00 - 13.45 Klinische Fälle aus der Allergologie: „Wie hätten Sie entschieden”

27

Information on Posters

Poster TopicsP01 T-Lymphocytes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P001 – P056P02 Innate Immunity: Antigen-Presenting Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P057 – P075P03 Signal Transduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P076 – P094P04 Tumor Immunology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P095 – P117P05 Innate Immunity: Regulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P118 – P134P06 Pattern Recognition Receptors & Myeloid Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P135 – P151P07 NK cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P152 – P164P08 Vaccines & Adjuvants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P165 – P187P09 Immunomodulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P188 – P208P10 Alloimmunity & Tolerance . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P209 – P233P11 Allergy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P234 – P264P12 Infection . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P265 – P296P13 Mucosal Immunity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P297 – P308P14 Autoimmunity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P309 – P352P15 B-Lymphocytes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P353 – P360P16 Regulatory Lymphocytes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P361 – P383P17 Cytokines, Chemokines & their receptors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P384 – P404P18 Veterinary Immunology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P405 – P418P19 Complement system . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . P420 – P420

• Posters will be on display from Wednesday, September 3, (15.00 hrs) to Saturday, September 6, 2008,(15.00 hrs).

• Poster mounting will be possible on: Wednesday, September 3, 2008 from 10:00 - 15:00.

• Removal will be possible on: Saturday, September 6, 2008 from 14:30 - 15:30.Please note that posters not removed by then, will be taken down by conference staff and will not be stored or forwarded to the authors after the meeting.

• You will find your poster board number in the author index at the end of the abstract book.

Presence at PostersIn order to enable discussion and interaction with other participants, we request you or another member of yourgroup to be at your poster board at the following times:

• Thursday, September 4, 2008, 09.30 – 10.30 hrsT-Lymphocytes-1 P001 - P028T-Lymphocytes-2 P029 - P056Innate Immunity: Antigen-Presenting Cells P057 - P075Signal Transduction P076 - P094Tumor Immunology P095 - P117

• Thursday, September 4, 2008, 15.30 – 16.30 hrsInnate Immunity: Regulation P118 - P134Pattern Recognition Receptors & Myeloid Cells P135 - P151NK Cells P152 - P164Vaccines & Adjuvants P165 - P187Immunomodulation P188 - P208

• Friday, September 5, 2008, 09.30 – 10.30 hrsAlloimmunity & Tolerance P209 - P233Allergy P234 - P264Infection P265 - P296Mucosal Immunity P297 - P308

• Friday, September 5, 2008 15.30 – 16.30 hrsAutoimmunity-1 P309 - P329Autoimmunity-2 P330 - P352B-Lymphocytes P353 - P360Regulatory Lymphocytes P361 - P383Cytokines, Chemokines & their receptors P384 - P404Veterinary Immunology P405 - P418Complement System P420

If this is not possible, please leave a note on your poster board detailing the times when you will be present at the board.

28

Information for Speakers

Projection and Technical Setting• All rooms will be equipped with data- and overhead projection (no slides).• It is essential that you load and view your presentation in the slide preview room preferably in the

morning of the day your talk is scheduled, but no later than 2 hours in advance.• The lecture rooms are exclusively equipped with Windows-PCs (no Macintosh machines). In case you

absolutely need to use your own laptop or notebook, please contact the preview center well in advance of your talk.

• Please bring a USB-stick or CD-ROM, all formatted for Windows® (PC). You may want to carry a second disk/CD as a back-up in case there is any unsolvable technical problem.

• File Format: Microsoft® Power Point™ presentation formatted for Windows® (PC) only. (Operatingsystem: Windows XP®)

• Preferred Resolution: XGA (1024 x 768 pixel)

Preview RoomThe Speaker’s Preview will be located in Room Nr. 11 on Level 7. Equipment for a final check of the sequence of yourpresentation is available in the preview room. All presenters should bring their electronic presentation to the previewroom preferably in the morning of the day of the talk, but no later than 2 hours before the start of the session. Forsessions starting at 08.15 hrs, the PowerPoint presentations should be handed in the previous day.Opening hours of the preview room:Wednesday, September 3, 2008 12.00 – 18.00Thursday, September 4, 2008 07.30 – 18.00Friday, September 5, 2008 07.30 – 18.00Saturday, September 6, 2008 08.15 – 15.00

Programme ChangesThe organisers cannot assume any liability for changes in the programme due to external or unforeseen circumstances.

29

Congress Information

Abstract BooksYou will find an Abstract Book in your conference bag.

Accreditation

The Joint Annual Meeting of Immunology has applied for credits at the European Accreditation Council for Con-tinuing Medical Education, Institution of the UEMS.The number of credits (which will be announced after the meeting) will figure on the respective confirmation,which will also be sent after the meeting.The rules of the EACCME state that participants are kindly asked to fill in the feedback (evaluation) form includedin the conference bag. It can be returned to the registration desk.

Participants applying for EACCME Credits will have to have their badge scanned daily at the registrationdesk before entering the conference. The confirmation will be mailed after the conference at the end ofSeptember.

Die österreichische Akademie der Ärzte hat an diese Veranstaltung 41 Diplomfortbildungspunktevergeben.

Admission to Lecture HallsParticipants are requested to enter the lecture halls via Level 8 only.

BadgesParticipants will receive their name badges from the conference registration desk. Since only registered participants will be per-mitted to attend scientific sessions, the exhibition and poster areas, you are kindly asked to wear your badge when entering thecongress venue. Please note that admission to scientific sessions is strictly restricted to participants wearing their badges. Ex-hibitors and accompanying persons are not entitled to attend the scientific sessions. Lost badges can be replaced at the regis-tration desk. However, a handling fee of € 20,- will be charged.

The following badge-colours are used at the Congress:

White � ParticipantsYellow � Accompanying PersonsGreen � ExhibitorsRed � Staff

Cancellations and RefundsNotice of cancellation must be made in writing by registered letter or fax to the Congress Office.The policy for refunding registration fees is as follows:Written cancellation received:- before July 31, 2008: 75% refund - after July 31, 2008: no refundThe date of the postmark or fax ID is the basis for considering refunds. Refunds will be made after the congress.

Cash BarSnacks and drinks may be purchased at the cash bar on Level 8 during congress hours.

Certificate of AttendanceConfirmations of attendance will be issued at the registration desk.

City TourThe city tour “Classical Vienna – A City Stroll” will take place on Thursday, September 4, 2008. It is free of charge for accompa-nying persons, however, registration in advance is mandatory.

Coffee BreaksDuring the session breaks, refreshments will be served free of charge to participants wearing name badges.

Exhibition Opening HoursWednesday, September 3, 2008 15.00 – 17.00 hrsThursday, September 4, 2008 08.15 – 17.00 hrsFriday, September 5, 2008 08.15 – 17.00 hrsSaturday, September 6, 2008 08.45 – 15.00 hrs

Hotel and Tours DeskMondial, the official travel agency of the meeting, will be present at the conference onWednesday, September 3, 2008 from 14.30 – 17.30 hrs and onThursday, September 4, 2008 from 07.30 – 09.30 hrs.If you have any questions regarding your hotel booking or the city tour, please approach Mondial. They will be located near theregistration desk.

InternetA few internet stations will be available at the conference. Please ask at the registration desk. You may also find small internetcafés throughout the city.

30

Congress Information

Message BoardA Message Board and notice of the daily programme are available on Level 7 and Level 8.

Poster Mounting and RemovalThere are four poster sessions: Thursday and Friday from 09.30 – 10.30 hrs and from 15.30 – 16.30 hrs. Poster mounting will bepossible on Wednesday, September 3, 2008 from 10.00 – 15.00 hrs. Poster removal will be possible on Saturday, September 6,2008 from 14.30 – 15.30 hrs. Please note that the organisers cannot assume any liability for loss or damage of posters displayedin the poster area. Posters that are not removed by 15.30 hrs on Saturday, September 6, 2008 will be removed by staff and willnot be stored or forwarded to the author after the meeting.

Preview RoomThe Speaker’s Preview will be located in Room Nr. 11 on Level 7. Equipment for a final check of the sequence of your presenta-tion is available in the preview room. All presenters should bring their electronic presentation to the preview room preferably inthe morning of the day of the talk, but not later than 2 hours before the start of the session. For sessions starting at 08.15 hrs,the PowerPoint presentations should be handed in the previous day.Following are the opening hours of the preview room:Wednesday, September 3, 2008 12.00 – 18.00Thursday, September 4, 2008 07.30 – 18.00Friday, September 5, 2008 07.30 – 18.00Saturday, September 6, 2008 08.15 – 15.00

Public TransportRegistered congress participants receive a 4-days-ticket when picking up their registration materials. This ticket is valid for all pub-lic transport within Vienna from Wednesday, September 3, 2008 to Saturday, September 6, 2008. This ticket is not valid for goingto the airport, since the airport is out of town. Congress participants are kindly requested to return their ticket if it is not needed.

Registration Desk opening hoursWednesday, September 3, 2008 10.00 – 18.00Thursday, September 4, 2008 07.30 – 18.00Friday, September 5, 2008 07.30 – 18.00Saturday, September 6, 2008 08.15 – 15.00

Smoking PolicyThe Joint Annual Meeting of Immunology is a “No-smoking-Conference”. Please note that smoking is banned from all publicbuildings. Restaurants and bars may, depending on size, be declared either as “smoking” or “no-smoking” locations or haveseparate areas and ventilation systems.

StaffShould you have any questions, congress staff, recognizable by a blue t-shirt and red badge, will be pleased to help you.

31

Registration Fees

Onsite registration

Wednesday, September 3, 2008 10.00 – 18.00Thursday, September 4, 2008 07.30 – 18.00Friday, September 5, 2008 07.30 – 18.00Saturday, September 6, 2008 08.15 – 15.00

What is covered by the registration fee?

Payment of registration fees may be made in cash (Euros only), by maestro debit card, or by the following credit cards: Diners Club, Mastercard, Visa.

Please note that the reduced registration fee is only applicable if it has been credited to the congress account before the dead-line. Registering without performing an actual payment is not sufficient to benefit from the reduction. Pre-registration withoutpayment of the registration fee is possible. The full fee is to be paid at the registration desk.

Cancellations and refunds:

Notice of cancellation must be made in writing by registered letter or fax to the Congress Office.

Notice of cancellation must be made in writing by registered letter or fax to the Congress Office.The policy for refunding registration fees is as follows:Written cancellation received:- before July 31, 2008: 75% refund - after July 31, 2008: no refundThe date of the postmark or fax ID is the basis for considering refunds. Refunds will be made after the congress.

32

Payment received before June 15, 2008 after June 15, 2008 and on-site

Members EUR 190.— EUR 300.—

Student Members* EUR 95.— EUR 135.—

Non-Members EUR 280.— EUR 390.—

Student Non-Members* EUR 140.— EUR 180.—

Accompanying Persons EUR 60.— EUR 60.—

Day Ticktet Member EUR 140,—

Day Ticket Non-Member EUR 180,—

* please provide a copy of an ID together with your registration

Participants Accompanying persons

• Admission to all scientific sessions• Access to the exhibition • Coffee breaks• Welcome reception at the City Hall

Thursday, September 4, 2008, 19.00 hrs• Abstract book• Programme• 4-days public transport ticket

• Admission to the welcome reception at the City HallThursday, September 4, 2008, 19.00 hrs

• Classical Vienna City Tour*,Thursday, September 4, 2008, 09.00 hrs

• Access to the exhibition and coffee breaks

(no admission to lectures)

*Please note that the classical city tour is not available foron site registrations of accompanying persons.

General Information

Bank services - Money mattersBanks are open from 8.30 – 12:30 and from 13:30 – 15:00, Monday to Friday. Some banks are also open on Thursday afternoonsuntil 17:30 hrs. Cash machines (ATMs), which accept all major international bank cards, are available throughout the city. Thereis a cash machine in the main entrance of the Vienna General Hospital. The currency of Austria is the Euro (€). Major credit cardsare widely accepted, but please always check beforehand.

Car ParkingThe Vienna General Hospital has approximately 800 car parking spaces available for visitors in an underground car park. Theentrance is at Währinger Gürtel.

Eating out in Vienna Vienna has a broad variety of local and international restaurants, many of them located in the old city and in the vicinity of the con-ference venue.

Emergency servicesThe phone number to dial for emergencies is 112.

GSM cell phone roaming GSM cell/mobile phone roaming is available without any problems for all major international providers. It is advisable to inquirebeforehand at your provider which roaming company in Austria offers the cheapest tariffs.

InsuranceIn registering for the Joint Annual Meeting of Immunology 2008 participants agree that neither the organising committee northe congress office assume any liability whatsoever. Participants are requested to make their own arrangements for health andtravel insurance.

Internet and printing facilitiesA few internet stations will be available at the conference. Please ask at the registration desk. You may also find small internetcafés throughout the city.

LanguageThe official language of the congress will be English (no simultaneous translation).

Medical careThe Austrian National Health Service may be used by all persons from European Union countries who have the E111 Form (EHI-Card). This form/card should be obtained at the health service or post office of the visitor’s home country before travelling toAustria. It is advisable for participants from countries outside the European Union to take out medical insurance before reachingAustria, since they will be charged for access to the national health system.

PharmaciesMedicines that do not require a medical prescription may be purchased over the counter. If you need advice, do not hesitate toask the pharmacist. If you usually take medication, it is advisable to bring a sufficient amount with you for your trip. Pharmaciesin the vicinity of the conference venue are on Zimmermannplatz 1, 1090 Vienna. There are duty pharmacies open 24 hours a day.Outside each pharmacy there is a list of the nearest duty pharmacies, or you may ask at your hotel reception for more informa-tion.

Safety - CrimeVisitor safety is generally adequate. Like in any other major European city, you can walk everywhere using common sense. Pickpocketing in heavily visited tourist zones or in public transport lines might be a concern. Unfortunately experience has shown that some basic precautionary measures should always be kept in mind in any city:- Do not carry important items like flight tickets, passports etc. with you when visiting the conference or strolling through the city;leave them in the hotel safe during your stay. Rather carry a photocopy of your passport or an identity card with you.- Try not to carry all documents, money, credit cards and other essential items and valuables in one bag. If it gets lost or stolen,everything will be gone and might be difficult to replace on short notice, especially passports and visa to return to your countryof residence. - Take off your name badge when leaving the conference centre.

ShopsShops in Vienna are generally open between 09.00 and 18.00 hrs Mon-Fri, and between 09.00 and 12.00 on Saturdays. Someshops are open until 19.00 Mon-Fri and until 17.00 on Saturdays. Shops are usually closed on Sundays, except for a few estab-lishments with special permits.

TaxisThere are Taxi ranks throughout the city, but calling is often your best option. Please address your hotel reception or the regis-tration desk of the conference venue. A taxi station can be found in front of the main entrance at Level 5 and at Lazarettgasse(exit on Level 4).

TippingTips are not obligatory in Austria, although people usually tip approximately 10% at restaurants, cafés and bars. Hotel and air-port porters will accept tips, depending on the luggage.

33

General Information

Travelling within Vienna

Registered congress participants receive a 4-days-ticket when picking up their registration materials. This ticket is valid for all pub-lic transport within Vienna from Wednesday, September 3, 2008 to Saturday, September 6, 2008. This ticket is not valid for goingto the airport, since it is out of town. Congress participants are kindly requested to return their ticket if it is not needed.

For accompanying persons and exhibitors tickets are available from machines at underground stations (maestro debit cards ac-cepted), at news agents’, or at Vienna Transport Authority’s ticket offices. Tickets bought in advance are cheaper and must bepunched in a blue ticket cancelling machine on the tram or bus, or at the barrier before boarding the underground train.

Single trip tickets can be used for any single trip within Vienna. You may change lines (and switch between bus, tram, under-ground, or urban train), but you may not interrupt your journey. Ticket price: EUR 1.70 when bought in advance; EUR 2.20 whenbought in the means of transport.The 24-hour pass is valid throughout Vienna for exactly 24 hours from the time it is punched. Price: EUR 5.70The 72-hour pass is valid throughout Vienna for exactly 72 hours from the time it is punched. Price: EUR 13.60The 8-day ticket is valid for any eight days, not necessarily eight consecutive days. It is a rover ticket, which means you can travelall around Vienna. You can also use the ticket for several people travelling together. Simply punch one strip for each person in thegroup. Price: EUR 27.20Week-pass valid from Monday to Monday, 09.00 hrs. Price: EUR 14.00

A taxi is the most comfortable way of getting around the city but also the most expensive. They are identifiable by their roof-signwhich is lit when available. Prices must be displayed inside the cab and meters (which are compulsory in all cabs) will indicatethe fare.

Travelling from and to the Airport

Vienna International Airport is located 13 kilometres south east of Vienna.

City Airport Train (CAT)The train service between the airport and the city centre (City Air Terminal – Station ‘Wien Mitte’) is every 30 minutes and takes16 minutes. It is covered from 6:05 hrs to 00:05 hrs (Airport to City) and from 5:38 hrs to 23:38 hrs (City to Airport). Tickets maybe purchased online (EUR 8.00 single or EUR 15.00 return), from ticket machines at the airport/station (EUR 9.00 single or EUR16.00 return) or on board (EUR 10.00 single). From ‘Wien Mitte’ you can take the green line (U4) direction Heiligenstadt and getoff at ‘Spittelau’ (five stops) and then take the brown line (U6) direction Siebenhirten and get off at Michelbeuern-AllgemeinesKrankenhaus.

Taxi fares to the conference venue are about EUR 35.00 and take around 25 minutes. There is a taxi rank outside the airport ter-minal. Night-time fees are slightly higher.

Travelling to the Vienna General Hospital by Public TransportationThe Vienna General Hospital (the congress venue) is easily reachable by taking the subway line U6 (the brown line) and gettingoff at Michelbeuern – Allgemeines Krankenhaus. Furthermore, it can be reached by tramway 42, tramways 5 and 33 (stopLazarettgasse) as well as tramways 43 and 44 (stop Alser Straße).

ViennaVienna, the capital of Austria, 2 million inhabitants, is situated on the banks of the Danube. Vienna is a dream city for anyone withan interest in history. Narrow, medieval alleyways and grand boulevards lead to historic sights such as the Imperial Palace (Hof-burg), Belvedere Palace, Burgtheater, the Spanish Riding School, St. Stephen’s Cathedral, the Opera House, Karlskirche, orSchönbrunn Palace. Vienna has been synonymous with music for centuries, and was home to Mozart, Beethoven, Schubert andJohann Strauss. The Vienna Philharmonic Orchestra is one of the world’s top orchestras; the Vienna Boys’ Choir is triumphantlysuccessful wherever it tours. Vienna possesses a lively and vast array of cultural attractions, from classical or experimental the-atre, film or dance festivals, opera or operetta, to exhibitions and concerts. The Museum of Fine Arts is one of the world’s largestand most distinguished museums, housing priceless works of art. Art accompanies you wherever you go in Vienna - even someof its underground stations are listed properties on account of their elegant, ornamental Jugendstil (Art Nouveau) style designedby Otto Wagner. For more information about Vienna, please see www.aboutvienna.org.

34

Venue

Location of the Vienna General Hospital and the Lecture Centre

Public transportation in ViennaThe Vienna General Hospital (the congress venue) is easily reachable by taking the subway line U6 and getting offat the station ”Michelbeuern – Allgemeines Krankenhaus”. Furthermore it can be reached with the tramway 42, thetramway 5 and 33 (station ”Lazarettgasse”) as well as the tramways 43 and 44 (station ”Alser Strasse”)

35

GENERAL INFORMATIONCongress venueVienna General HospitalAllgemeines Krankenhaus WienLecture Hall CentreHörsaalzentrumWähringer Gürtel 18-20A-1090 Vienna, Austria

HÖRSAALZENTRUM

EBENE 07/08

Venue 36

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LectureHall 1

LectureHall 3

LectureHall 2

LectureHall 5

LectureHall 4

Escalators to main entranceGreen Elevators to main entrance

Red Elevators

PreviewRoom

Registration

MeetingRoom 13

Coffee

Cof

fee

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Exhibition

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Cloak-room

Level 7Access from main entrance

No entrance to Lecture Halls.Please use the doors on Level 8.

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LectureHall 1

LectureHall 3

LectureHall 2

LectureHall 5

LectureHall 4

Escalators to main entranceGreen Elevators to main entrance Red Elevators

MeetingRoom

25

Posters

Posters

Posters and Exhibition

sretsoPraB hsa

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Coffee

Level 8Access to Lecture Halls

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?

? Entrance to Lecture Halls

Posters

Post

ers

Social Events

Thursday, September 4, 2008, 19.00 hrs

Welcome Reception by the Mayor of Vienna at the Vienna City Hall

The mayor of the city of Vienna is pleased to invite you to a Welcome Reception. Meet your colleagues at this event. Enjoy theevening with a Buffet and live music.

Dress code: business attire

Attendance is free for registered participants and accompanying persons. Those who have registered prior to the congressshould have received their ticket with the congress material. Please remember to bring your ticket.

Please note that attendance is limited and advance registration is mandatory in order to receive a ticket!A limited number of tickets will still be available for onsite bookings.

Venue: Vienna City Hall, Lichtenfelsgasse 2, 1010 Vienna

Directions: From the conference venue take the brown underground line U6 (direction Siebenhirten) one stop and get off at AlserStrasse. Take the tram 43 (direction Schottentor) and get off at Landesgerichtsstrasse. From there you can walk along Landes-gerichtsstrasse until you reach the city hall on your left hand side. Walk past the city hall and turn left into Lichtenfelsgasse. Theentrance to the reception is on your left.

Alternatively you can take the brown underground line U6 (direction ‘Floridsdorf’) three stops and get off at ‘Spittelau’. Take thegreen underground line U4 (direction ‘Hütteldorf’) three stops and get off at ‘Schottenring’. Take the purple underground line U2(direction ‘Karlsplatz’) two stops and get off at ‘Rathaus’. Take the exit towards the front of the train and turn left and cross thestreet. This is Lichtenfelsgasse. The entrance to the Reception is on the left hand side.

Friday, September 5, 2008, 19.30 hrs.

Dinner at a Viennese “Heuriger”

An evening spent in typical Austrian wine taverns in Vienna. You will be served a delicious Austrian buffet and excellent localwines while enjoying the atmosphere of a traditionally decorated restaurant. “Heuriger” could be translated with “of this year”and means a young crisp wine produced during the current wine season. Only wine producers serving their own product,grown in the vineyards of Vienna, may call their tavern “Heuriger”.

Dress code: casual

Venue: Weingut Fuhrgassl Huber Neustift/Walde 681190 Vienna

Buses depart from the main entrance on Level 5 of the Vienna General Hospital, at 19.30 hrs and return in the lateevening.

Price per ticket including transport, music, food and beverages: EUR 45.–

Please note that advance registration is mandatory in order to receive a ticket! A limited number of tickets will still beavailable for onsite bookings.

37

Underground Map 38

9

Congressvenue

WelcomeReception

City Map 39

1) Lecture Centre of the ViennaGeneral Hospital (AKH)

2) City Hall (Welcome Reception)3) Arcotel Boltzmann4) Mercure Josefshof5) Hotel & Palais Strudlhof6) Carlton Opera

7) Wandl8) Atlas9) Academia10) Pension Ani Falstaff11) Pension Ani12) Regina13) Royal

Exhibition – General Information

Exhibiton Organiser:

Name MAW – Medizinische Ausstellungs- und WerbegesellschaftAddress Freyung 6

1010 Vienna, Austria

Telephone Ms. Ingrid Winkler: +43 664 441 8285Ms. May-Britt Ernst: +43 664 105 2018

Fax +43 1 535 6016E-mail [email protected]

Exhibition Dates & Opening hours:

Wednesday, September 3, 2008 15.00 – 17.00 hrsThursday, September 4, 2008 08.15 – 17.00 hrsFriday, September 5, 2008 08.15 – 17.00 hrsSaturday, September 6, 2008 08.45 – 15.00 hrs

Poster Mounting, Poster Viewing, Poster Removal Hours

Wednesday, September 3, 2008 – poster mounting 10.00 – 15.00 hrsWednesday, September 3, 2008 – poster viewing 15.00 – 18.00 hrsThursday, September 4, 2008 – poster viewing 08.15 – 18.00 hrsFriday, September 5, 2008 – poster viewing 08.15 – 18.00 hrsSaturday, September 6, 2008 – poster viewing 08.45 – 14.30 hrsSaturday, September 6, 2008 – poster removal 14.30 – 15.30 hrs

Location

Venue Lecture Centre of the Vienna General HospitalExhibition Areas Level 7 and Level 8Address Währinger Gürtel 18-20, 1090 Vienna, Austria

40

List of Sponsors, Exhibitors and Advertisers*

Ärztezentrale Adressen- und Drucksortenverlag, Vienna, Austria

Abd Serotec- Endeavour House, Oxon, United Kingdom

Acris Antibodies, Hiddenhausen, Germany

Active Motif Europe, Rixensart, Belgium

Aesca Pharma, Traiskirchen, Austria

Alk Abello Allergie – Service GmbH, Linz, Austria

Allergopharma, Vienna, Austria

AstraZeneca Österreich, Vienna, Austria

Becton Dickinson Austria, Schwechat, Austria

Bencard Allergie, Vienna, Austria

Bender Medsystems, Vienna, Austria

Biomedica, Vienna, Austria

Bio-Rad Laboratories, Munich, Germany

Biotest AG, Dreieich, Germany

Biozym Biotech Trading, Vienna, Austria

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany

CellGenix Technologie Transfer, Freiburg, Germany

Cell Kinetice, Lod, Israel

2nd European Congress of Immunology – ECI 2009

eubio, Vienna, Austria

Fermentas, St. Leon-Rot, Germany

GE Healthcare Europe, Vienna, Austria

Greiner Bio – One, Kremsmünster, Austria

Hal Allergy, Vienna, Austria

*(as per printing date)

41

List of Sponsors, Exhibitors and Advertisers*

Invitrogen, Karlsruhe, Germany

Jackson ImmunoResearch Europe Ltd., Suffolk, United Kingdom

LaVision BioTec, Bielefeld, Germany

Mabtech AB, Nacka Strand, Sweden

Ferdinand Menzl Medizintechnik, Vienna, Austria

Miltenyi Biotec, Bergisch Gladbach, Germany

NatuTec, Frankfurt am Main, Germany

New England Biolabs, Frankfurt am Main, Germany

Novartis Pharma, Vienna, Austria

Octapharma, Lachen, Switzerland

Partec, Görlitz, Germany

PeproTech, Hamburg, Germany

Phadia Austria, Vienna, Austria

Porsche Austria

ProFas, Regensburg, Germany

Charles River Consulting, Sulzfeld, Germany

Roche Austria, Vienna, Austria

R + D Systems, Wiesbaden, Germany

Siemens Medical Solutions Diagnostics, Vienna, Austria

Stallergenes France, Antony Cedex, France

Stemcell Technologies, Grenoble, France

tebu – bio, Offenbach, Germany

THP Medical Products, Vienna, Austria

Werfen Austria, Vienna, Austria

Wiley Blackwell, Weinheim, Germany

Yakult Deutschland, Neuss Germany

*(as per printing date)

42

Notes

Printed in Austria by: ROBIDRUCK, 1200 Vienna – www.robidruck.co.at

Das Immunglobulin inseiner natürlichen Form

Natur weitergeben

Zusammensetzung: 1 ml Intratect® enthält 50 mg Plasmaproteine vom Menschen, davon mind. 96 % IgG (57,2 % IgG1, 37,2 % IgG2, 3,1 % IgG3, 3,0 % IgG4). Höchstgehalt an IgA: 2 mg/ml. Hilfsstoffe: Glycin, Wasser zur Injektion. Anwendungsgebiete: Substitutionstherapie bei primären Immunmangelsyndromen, sekundärer Hypogammaglobulinämie und rezidivierenden bakteriellen Infektionen bei CLL und multiplem Myelom, Kinder mit angeborenem AIDS und rezidivierenden Infektionen. Immunmodulation bei ITP bei Kindern oder Erwachsenen mit einem hohen Blutungsrisiko oder vor chirurgischen Eingriffen zur Korrektur der Thrombozytenzahl, Guillain-Barré-Syndrom und Kawasaki-Syndrom. Allogene Knochenmarktransplantation. Art der Anwendung, Dosierung: Intratect® wird intravenös verabreicht. Dosierung und Intervalle der Infusionen richten sich nach der Indikation. Gegenanzeigen: Überempfi ndlichkeit gegen jegliche Bestandteile des Präparates. Überempfi ndlichkeit gegen homologe Immunglobuline, insbesondere in den sehr seltenen Fällen von IgA-Mangel, wenn der Patient Antikörper gegen IgA aufweist. Spezielle Hinweise: Bestimmte schwere unerwünschte Nebenwirkungen können im Zusammenhang mit der Infusionsgeschwin-digkeit stehen. Es ist die in der Gebrauchsinformation beschriebene Infusionsgeschwindigkeit zu beachten. Die Patienten müssen während der gesamten Dauer der Infusion kontrolliert und auf Symptome uner-wünschter Wirkungen beobachtet werden. Bestimmte unerwünschte Nebenwirkungen können bei einer hohen Infusionsgeschwindigkeit häufi ger auftreten, bei Patienten mit Hypo- oder Agammaglobulinämie mit oder ohne IgA-Mangel, bei Patienten, die zum ersten Mal Immunglobulin vom Menschen erhalten oder, in seltenen Fällen, bei einem Wechsel des Immunglobulin-Präparates oder nach einer längeren Behand-lungspause. Nebenwirkungen: Gelegentlich können Schüttelfrost, Kopfschmerzen, Fieber, Übelkeit und Erbrechen, allergische Reaktionen, niedriger Blutdruck, Gelenkschmerzen und leichte Rückenschmerzen. Selten: plötzlicher Blutdruckabfall, vorrübergehende Hautreaktionen, Anstieg des Serumkreatinin-Spiegels, akutes Nierenversagen, thromboembolische Komplikationen. In Einzelfällen: anaphylaktischer Schock, reversible aseptische Meningitis, reversible hämolytische Anämie/Hämolyse. Wechselwirkungen: Die Gabe von Immunglobulin kann für eine Dauer von mindestens 6 Wochen und bis zu 3 Monaten die Wirksam-keit von attenuierten Lebendimpfstoffen wie Masern-, Röteln-, Mumps- und Windpockenimpfstoffen beeinträchtigen. Nach der Gabe dieses Präparates ist vor der Impfung mit attenuierten Lebendimpfstoffen eine Wartezeit von 3 Monaten einzuhalten. Bei Masernimpfung kann diese Beeinträchtigung bis zu einem Jahr fortbestehen. Daher sollte bei Patienten, die Masernimpfstoff erhalten, der Antikörperstatus über-prüft werden. Handelsformen: Gebrauchsfertige Lösung zur intravenösen Infusion in Durchstichfl aschen aus Glas zu 20 ml (1,0 g), 50 ml (2,5 g), 100 ml (5,0 g) und 200 ml (10,0 g).

Biotest Pharma GmbH · Postfach 10 20 40 · D-63266 Dreieich · www.biotest.de

Intratect_DGN.260706.indd 1 01.08.2006 11:41:20 Uhr

JOINT ANNUAL MEETING OF IMMUNOLOGY OF THE AUSTRIAN … · arising not only in basic innate and...

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