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Prof Dr rer nat Michael NaumannMedizinische FakultaumltUniversitaumltsklinikum AoumlR (FMEUKMD)Institut fuumlr Experimentelle Innere Medizin (IEIM)

Haus 05 Leipziger Str 44 39120 Magdeburg H5316

Tel +49 391 67-13227 Fax +49 391 67-13312

NaumannmedovgudeHomepageProjekte

Aktuelle Projekte

Maladaptive processes across physiological barriers in chronic diseasesLaufzeit 01102018 - 31032023

Helicobacter pylori type IV secretion system-directed membrane-proximal NF-kBsignalingLaufzeit 01012018 - 31122021

Plasticity and cell-type specific functions of OTUB1 in infectionLaufzeit 01012018 - 31122021

ZIKAlliance Project 53Laufzeit 01102016 - 30092020

Abgeschlossene Projekte

Immunregulatory function of the deubiquitinylating enzymes A20 and OTUB1 ininfectious and autoimmune diseasesLaufzeit 01012014 - 31122017

E3 Ubiquitin Ligase-abhaumlngige NF-kB Regulation in der Helicobacter pylori InfektionLaufzeit 01012014 - 31122017

Identifizierung neuer Zielmolekuumlle fuumlr die klinische Therapie der akuten myeloischenLeukaumlmieLaufzeit 01062014 - 31052017

Proteomanalytik und MassenspektrometrieLaufzeit 01122012 - 31122015

NF-kB Regulation in der Helicobacter InfektionLaufzeit 01012010 - 31122013

Immunregulatorische Funktion von Deubiquitinylasen bei der ToxoplasmoseLaufzeit 01012010 - 31122013

MODEXALaufzeit 01092009 - 31082012

Nedd8COP9 Signalosom-abhaumlngige Kontrolle von IkBs und RelALaufzeit 01102008 - 31082012


Stimulus-dependent molecular processes in cellsLaufzeit 01042007 - 31122011

Modellierung der NF-kB SignaltransduktionLaufzeit 01012007 - 31122011

Dynamics of Helicobacter pylori-induced responses in epithelial cellsLaufzeit 01012007 - 31122011

Bilaterale KooperationLaufzeit 01092010 - 30062011

Regulation der IkBNF-kB Signaltransduktion in der H pylori-induziertenangeborenen ImmunantwortLaufzeit 01012007 - 31122010

Zell-Zell-Kommunikation in Nerven- und Immunsystem Topologische Organisationvon SignalwegenLaufzeit 01102005 - 31032010

Modulation des Wnt-Signalweges und Bedeutung fuumlr die Invasion von EpithelzellenLaufzeit 01102005 - 31032010

Regulation of the lipid-raft localised signal transduction in Helicobacter pylori infectionLaufzeit 01102005 - 31032010

Funktionelle Analyse signaluumlbertragender ProteinkomplexeLaufzeit 01072008 - 31122009

Funktionelle Analyse signaluumlbertragender Proteinkomplexe in Lipid-raft-StrukturenHelicobacter-pylori-infizierter EpithelzellenLaufzeit 01072005 - 30062008

Chromatin-assoziierte Veraumlnderungen von Wnt-Zielgenen nach Helicobacter pyloriInfektion im MagenepithelLaufzeit 01092005 - 31082007

Zelldissoziation und Dysregulation von adherens junction Proteinen im Helicobacterpylori-infizierten MagenepithelLaufzeit 01092004 - 31082007

Induktion der angeborenen Immunantwort durch Membran-InteraktionTranslokation

von Helicobacter pylori Effektoren und Aktivierung der intrazellulaumlrenSignaltransduktion in EpithelzellenLaufzeit 01012004 - 31122006

Mathematische Modellierung der Signaltransduktion bei der Stimulation desTyrosinkinase Rezeptors c-Met durch HGF und Helicobacter pyloriLaufzeit 01102004 - 30092006

Regulation von NF-kappaB und MAP-Kinase Signalwegen bei chronischentzuumlndlichen DarmerkrankungenLaufzeit 01012004 - 31122005

Signalwege zur NF-kappaB Regulation Charakterisierung der NF-kappaB KinasenLaufzeit 01022000 - 30012005

Helicobacter pylori- induzierte Histidindecarboxylase-Genaktivitaumlt in gastralenEpithelzellen Charakterisierung der molekularen Mechanismen und VirulenzfaktorenLaufzeit 01022001 - 30012004

Publikationen

2019

Abstrakt

Cyran Anna-Maria Sprung Susanne Naszlig Norbert Naumann Michael Arens Christoph Haybaumlck Johannes

Expression levels of eukaryotic initiation factors (eIFs) are significantly altered in headand neck squamous cell carcinomas (HNSCC)In Der Pathologe - Berlin Springer Bd 402019 Suppl 2 AG1105 Seite S139

rsaquoPublikationslink

Koschel Josephin Nishanth Gopala Just Sissy Naumann Michael Schluumlter Dirk

Role of Otubain-1 (OTUB1) during inflammatory liver diseasesIn European journal of immunology - Weinheim Wiley-VCH Bd 492019 Suppl 1O1 Seite 13


Begutachteter Zeitschriftenartikel

Ghanem Ahmed Schweitzer Katrin Naumann Michael

Catalytic domain of deubiquitinylase USP48 directs interaction with Rel homologydomain of nuclear factor kappaB transcription factor RelA

In Molecular biology reports - Dordrecht [ua] Springer Science + Business MediaBV Bd 462019 1 S 1369-1375


Sokolova Olga Naumann Michael

Crosstalk between DNA damage and inflammation in the multiple steps of gastriccarcinogenesisIn Current topics in microbiology and immunology - Berlin Springer Bd 4212019 S107-137


Maubach Gunter Feige Michael H Lim Michelle C C Naumann Michael

NF-kappaB-inducing kinase in cancerIn Biochimica et biophysica acta Reviews on cancer - Amsterdam Elsevier Bd18712019 1 S 40-49


Hillert Laura K Bettermann-Bethge Kira Nimmagadda Subbaiah Chary Fischer Thomas Naumann Michael Lavrik Inna N

Targeting RIPK1 in AML cells carrying FLT3-ITDIn International journal of cancer - Bognor Regis Wiley-Liss Bd 1452019 6 S1558-1569


2018


Kumar Vikash Naumann Michael Stein Matthias

Computational studies on the inhibitor selectivity of human JAMM deubiquitinylasesRpn11 and CSN5In Frontiers in Chemistry - Lausanne Frontiers Media Bd 62018 Art-Nr 480insges 12 S


Studencka-Turski Maja Maubach Gunter Feige Michael Hartmut NaumannMichael

Constitutive activation of nuclear factor kappa B-inducing kinase counteracts apoptosisin cells with rearranged mixed lineage leukemia geneIn Leukemia - London Springer Nature Bd 322018 11 S 2498-2501


Dubiel Wolfgang Dubiel Dawadschargal Wolf Dieter A Naumann Michael

Cullin 3-based ubiquitin ligases as master regulators of mammalian cell differentiation

In Trends in biochemical sciences TIBS - Amsterdam [ua] Elsevier Science Bd432018 2 S 95-107


Naghavi Lara Schwalbe Martin Ghanem Ahmed Naumann Michael

Deubiquitinylase USP47 promotes RelA phosphorylation and survival in gastric cancercellsIn Biomedicines open access journal - Basel MDPI Bd 62018 2 Art-Nr 62insges 9 S


Dash Banaja Priyadarshini Schnoumlder Tina Kathner Carolin Mohr Juliane Weinert Soumlnke Herzog Carolin Godavarthy Parimala Sonika ZanettiCostanza Perner Florian Braun-Dullaeus Ruumldiger Hartleben Bjoumlrn HuberTobias B Walz Gerd Naumann Michael Ellis Sarah Vasioukhin Valera Kaumlhne Thilo Krause Daniela Sandra Heidel Florian

Diverging impact of cell fate determinants Scrib and Llgl1 on adhesion and migration ofhematopoietic stem cellsIn Journal of cancer research and clinical oncology official organ of the DeutscheKrebsgesellschaft - Berlin Springer Bd 1442018 10 S 1933-1944


Feige Michael Hartmut Vieth Michael Sokolova Olga Taumlger Christian Naumann Michael

Helicobacter pylori induces direct activation of the lymphotoxin beta receptor and non-canonical nuclear factor-kappa B signalingIn Biochimica et biophysica acta Molecular cell research - Amsterdam [ua]Elsevier Bd 18652018 4 S 545-550


Feige Michael Hartmut Sokolova Olga Pickenhahn Anna Maubach Gunter Naumann Michael

HopQ impacts the integrin [alpha]5[beta]1-independent NF-[kappa]B activation byHelicobacter pylori in CEACAM expressing cellsIn International journal of medical microbiology - Muumlnchen Elsevier Bd 3082018 5S 527-533


Gantenbein Nadine Bernhart Eva Anders Ines Golob-Schwarzl Nicole Krassnig Stefanie Wodlej Christina Brcic Luka Lindenmann Joerg Fink-Neuboeck Nicole Gollowitsch Franz Stacher-Priehse Elvira AsslaberMartin Gogg-Kamerer Margit Rolff Jana Hoffmann Jens SilvestriAlessandra Regenbrecht Christian Reneacute Alexander Reinhard Christoph Pehserl Anna-Maria Pichler Martin Sokolova Olga Naumann Michael Mitterer Valentin Pertschy Brigitte Bergler Helmut Popper Helmut SattlerWolfgang Haybaumlck Johannes

Influence of eukaryotic translation initiation factor 6 on nonsmall cell lung cancerdevelopment and progressionIn European journal of cancer - Amsterdam [ua] Elsevier Bd 1012018 S 165-180


Sokolova Olga Kaumlhne Thilo Bryan Kenneth Naumann Michael

Interactome analysis of transforming growth factor-[beta]-activated kinase 1 inHelicobacter pylori-infected cells revealed novel regulators tripartite motif 28 andCDC37In OncoTarget open access impact journal - [Sl] Impact Journals LLC Bd 9201818 S 14366-14381


Lim Michelle CC Maubach Gunter Naumann Michael

NF-[kappa]B-regulated ubiquitin-editing enzyme A20 paves the way for infectionpersistencyIn Cell cycle - Abingdon Taylor amp Francis Group Bd 172018 1 S 3-4


Mohr Juliane Dash Banaja Priyadarshini Schnoumlder Tina WolleschakDenise Herzog Carolin Santamaria Nuria Tubio Weinert Soumlnke Godavarthy Sonika Zanetti Costanza Naumann Michael Hartleben Bjoumlrn Huber Tobias B Krause Daniela Sandra Kaumlhne Thilo Bullinger Lars Heidel Florian

The cell fate determinant Scribble is required for maintenance of hematopoietic stemcell functionIn Leukemia normal and malignant hemopoiesis a peer-reviewed journal - LondonSpringer Nature Bd 322018 5 S 1211-1221


2017

Abstrakt

Herrera-Molina Rodrigo Vemula Sampath Kumar Naumann Michael Seidenbecher Constanze Gundelfinger Eckhard D

A new way to create synapses - neuroplastin-TRAF6-dependent signaling inducesexcitatory synapse formationIn Journal of neurochemistry official journal of the International Society forNeurochemistry JN - Oxford Wiley-Blackwell Bd 1422017 Suppl 1 MTU08-08 S130


Schmid Ursula Stenzel Werner Koschel Josephin Raptaki Maria WangXu Naumann Michael Matuschewski Kai Schluumlter Dirk Nishanth Gopala

CYLD-deficiency protects from experimental cerebral malariaIn European journal of immunology - Weinheim Wiley VCH Bd 472017 Suppl 2O74 S 42



Korthals Mark Langnaese Kristina Smalla Karl-Heinz Kaumlhne Thilo Herrera-Molina Rodrigo Handschuh Juliane Lehmann Anne-Christin MamulaDejan Naumann Michael Seidenbecher Constanze Zuschratter Werner Tedford Kerry Gundelfinger Eckhard D Montag Dirk Fischer Klaus-Dieter Thomas Ulrich

A complex of neuroplastin and plasma membrane Ca2+ ATPase controls T cellactivationIn Scientific reports - [London] Macmillan Publishers Limited part of Springer NatureBd 72017 Art-Nr 8358 insges 13 S


Boumlge Yannick Thimotheus Malehmir Mohsen Healy Marc E BettermannKira Lorentzen Anna Vucur Mihael Ahuja Akshay Kumar BoumlhmFriederike Mertens Joachim C Shimizu Yutaka Frick Lukas Remouchamps Caroline Mutreja Karun Kaumlhne Thilo SundaravinayagamDevakumar Wolf Monika J Rehrauer Hubert Koppe Christiane SpeicherTobias Padrissa-Alteacutes Susagna Maire Renaud Schattenberg Joumlrn Markus Jeong Ju-Seong Liu Lei Zwirner Stefan Boger Regina Huumlser Norbert Davis Roger J Muumlllhaupt Beat Moch Holger Schulze-Bergkamen Henning Clavien Pierre-Alain Werner Sabine Borsig Lubor Luther Sanjiv A JostPhilipp J Weinlich Ricardo Unger Kristian Behrens Axel Hillert Laura Dillon Christopher Virgilio Michela Wallach David Dejardin Emmanuel Zender Lars Naumann Michael Walczak Henning Green Douglas R Lopes Massimo Lavrik Inna N Luumldde Tom Heikenwaumllder Mathias WeberAchim

A dual role of caspase-8 in triggering and sensing proliferation-associated DNAdamage a key determinant of liver cancer developmentIn Cancer cell - Cambridge Mass Cell Press Bd 322017 3 S 342-359


Zimmermann Stephanie Pfannkuch Lennart Al-Zeer Munir A BartfeldSina Koch Manuel Liu Jianping Rechner Cindy Soerensen Meike Sokolova Olga Zamyatina Alla Kosma Paul Maumlurer Andreacute Germar Paul Glowinski Frithjof Pleissner Klaus-Peter Schmid Monika BrinkmannVolker Karlas Alexander Naumann Michael Rother Marion MachuyNikolaus Meyer Thomas F

ALPK1- and TIFA-dependent innate immune response triggered by the helicobacterpylori type IV secretion system

In Cell reports - Maryland Heights MO Cell Press Bd 202017 10 S 2384-2395rsaquoPublikationslink

Ranjan Satish Goihl Alexander Kohli Shrey Gadi Ihsan Pierau Mandy Hussain Khurrum Shahzad Gupta Dheerendra Bock Fabian Maximilian Wang Hongjie Shaikh Haroon Kaumlhne Thilo Reinhold Dirk Bank Ute Zenclussen Ana Claudia Niemz Jana Schnoumlder Tina Brunner-WeinzierlMonika Fischer Thomas Kalinski Thomas Schraven Burkhart LuftThomas Huumlhn Jochen Naumann Michael Heidel Florian Isermann Berend

Activated protein C protects from GvHD via PAR2PAR3 signalling in regulatory T-cellsIn Nature Communications - [London] Nature Publishing Group UK Bd 82017Artikel-Nummer 311 16 Seiten


Dubiel Dawadschargal Bintig Willem Kaumlhne Thilo Dubiel Wolfgang Naumann Michael

Cul3 neddylation is crucial for gradual lipid droplet formation during adipogenesisIn Biochimica et biophysica acta Molecular cell research - Amsterdam [ua]Elsevier Bd 18642017 8 S 1405-1412


Yazdi Samira Naumann Michael Stein Matthias

Double phosphorylation-induced structural changes in the signal-receiving domain ofI[kappa]B[alpha] in complex with NF-[kappa]BIn Proteins structure function and bioinformatics - New York NY Wiley-Liss Bd852017 1 S 17-29



Double phosphorylation-induced structural changes in the signal-receiving domain ofIκBα in complex with NF-κBIn Proteins Structure Function and Bioinformatics 2017 S 17-29 ISSN 08873585101002prot25181

Naumann Michael Sokolova Olga Tegtmeyer Nicole Backert Steffen

Helicobacter pylori - a paradigm pathogen for subverting host cell signal transmissionIn Trends in microbiology - Amsterdam [ua] Elsevier Science Bd 252017 4 S316-328


Tegtmeyer Nicole Weszligler Silja Necchi Vittorio Rohde Manfred HarrerAileen Rau Tilman Tassilo Rupert Asche Carmen Isabell Boehm Manja Loumlszligner Holger Figueiredo Ceu Naumann Michael Palmisano Ralf SolciaEnrico Ricci Vittorio Backert Steffen

Helicobacter pylori employs a unique basolateral type IV secretion mechanism forCagA deliveryIn Cell host and microbe - Amsterdam [ua] Elsevier Bd 222017 4 S 552-560


Maubach Gunter Naumann Michael

NEMO links nuclear factor-[kappa]B to human diseasesIn Trends in molecular medicine - Amsterdam [ua] Elsevier Science Bd 23201712 S 1138-1155



NF[kappa]B signaling in gastric cancerIn Toxins - Basel MDPI Bd 92017 4 Art-Nr 119 insges 21 S


Lim Michelle CC Maubach Gunter Sokolova Olga Feige Michael H Diezko Rolf Christian Buchbinder Joumlrn Backert Steffen Schluumlter Dirk Lavrik Inna N Naumann Michael

Pathogen-induced ubiquitin-editing enzyme A20 bifunctionally shuts off NF-B andcaspase-8-dependent apoptotic cell deathIn Cell death and differentiation - Houndmills Basingstoke Nature Publishing GroupBd 242017 9 S 1621-1631


Backert Steffen Haas Rainer Gerhard Markus Naumann Michael

The Helicobacter pylori type IV secretion system encoded by the cag pathogenicityisland - architecture function and signalingIn Current topics in microbiology and immunology - Berlin Springer Bd 4132017 S187-220



The deubiquitinating enzyme cylindromatosis dampens CD8+ T cell responses and is acritical factor for experimental cerebral malaria and bloodbrain barrier damageIn Frontiers in immunology - Lausanne Frontiers Media Bd 82017 Art-Nr 27insges 17 S


2016

Abstrakt

Lim Michelle Maubach Gunter Diezko Rolf Christian Sokolova Olga Feige

Michael Buchbinder Joumlrn Lavrik Inna N Naumann Michael

NF-KappaB dependent expression of a20 controls cell death in H pylori-infected cellsIn Helicobacter - Oxford [ua] Wiley-Blackwell Bd 212016 Suppl 1 Abs P0903S 162


Just Sissy Nishanth Gopala Buchbinder Joumlrn Holger Wang Xu NaumannMichael Lavrik Inna N Schluumlter Dirk

A20 curtails primary but augments secondary CD8+ T cell responses in intracellularbacterial infectionIn Scientific reports - [London] Macmillan Publishers Limited part of Springer NatureBd 62016 Art-Nr 39796 insges 15 S

Kolodziej Angela Smalla Karl-Heinz Richter Sandra Engler Alexander Pielot Rainer Dieterich Daniela C Tischmeyer Wolfgang NaumannMichael Kaumlhne Thilo

High resolution quantitative synaptic proteome profiling of mouse brain regions afterauditory discrimination learning Video articleIn JoVE - [Sl] 2016 118 Art-Nr e54992 insges 12 S


Oh In Soo Textoris-Taube Kathrin Sung Pil Soo Kang Wonseok GornyXenia Kaumlhne Thilo Hong Seon-Hui Choi Young Joon Cammann Clemens Naumann Michael Kim Jong Hoon Park Su-Hyung Yoo Ook Joon Kloetzel Peter M Seifert Ulrike Shin Eui-Cheol

Immunoproteasome induction is suppressed in hepatitis C virus-infected cells in aprotein kinase R-dependent mannerIn Experimental amp molecular medicine EMM - [London] Macmillan Publishers Limitedpart of Springer Nature Bd 482016 Art-Nr e270 insges 10 S


Schleich Kolja Buchbinder Joumlrn Holger Pietkiewicz Sabine Kaumlhne Thilo Warnken Uwe Hans Oumlztuumlrk Selcen Schnoumllzer Martina Naumann Michael Krammer Peter H Lavrik Inna N

Molecular architecture of the DED chains at the DISC - regulation of procaspase-8activation by short DED proteins c-FLIP and procaspase-8 prodomainIn Cell death and differentiation - Houndmills Basingstoke Nature Publishing GroupBd 232016 4 S 681-694


Gummlich Linda Kaumlhne Thilo Naumann Michael Kilic Ergin Jung Klaus Dubiel Wolfgang

New insights into the mechanism of COP9 signalosomecullin-RING ubiquitin-ligasepathway deregulation in urological cancersIn International review of cell and molecular biology - Amsterdam [ua] Elsevier Bd3232016 S 181-229

Backert Steffen Neddermann Matthias Maubach Gunter Naumann Michael

Pathogenesis of Helicobacter pylori infectionIn Helicobacter - Oxford [ua] Wiley-Blackwell Bd 21 (2016) Suppl1 Seite 19-25


Kaumlhne Thilo Richter Sandra Kolodziej Angela Smalla Karl-Heinz PielotRainer Engler Alexander Ohl Frank W Dieterich Daniela C SeidenbecherConstanze Tischmeyer Wolfgang Naumann Michael Gundelfinger EckhardD

Proteome rearrangements after auditory learning - high-resolution profiling of synapse-enriched protein fractions from mouse brainIn Journal of neurochemistry official journal of the International Society forNeurochemistry JN - Oxford Wiley-Blackwell Bd 1382016 1 S 124-138


Wex Katharina Schmid Ursula Just Sissy Wang Xu Wurm Rebecca Naumann Michael Schluumlter Dirk Nishanth Gopala

Receptor-interacting protein kinase-2 inhibition by CYLD impairs antibacterial immuneresponses in macrophagesIn Frontiers in immunology - Lausanne Frontiers Media Bd 62016 Art-Nr 650insges 13 S




Schweitzer Katrin Pralow Alexander Naumann Michael

p97VCP promotes Cullin-RING-ubiquitin-ligaseproteasome-dependent degradation ofIBα and the preceding liberation of RelA from ubiquitinated IBαIn Journal of cellular and molecular medicine an international journal JCMM -Hoboken NJ Wiley-Blackwell Bd 202016 1 S 58-70


Nicht begutachteter Zeitschriftenartikel

Braun-Dullaeus Ruumldiger C

Das internistische Jahr 2015 - die wichtigsten Fortschritte und EntwicklungenIn Aumlrzteblatt Sachsen-Anhalt offizielles Mitteilungsblatt der Aumlrztekammer Sachsen-Anhalt - Magdeburg Aumlrztekammer Sachsen-Anhalt Bd 272016 5 S 19-22


2015

Abstrakt

Naumann Michael Feige Michael Sokolova Olga

The role of Helicobacter pylori-induced canonical- and non-canonical NF-KB signalingin cell survivalIn Helicobacter - Oxford [ua] Wiley-Blackwell Bd 202015 Suppl 1 Abs P0418S 108-109



Nguyen Thi-Xuan Wang Xu Nishanth Gopala Waisman Ari BoruckiKatrin Isermann Berend Naumann Michael Deckert Martina Schluumlter Dirk

A20 expression in dendritic cells protects mice from LPS-induced mortalityIn European journal of immunology - Weinheim Wiley-VCH Bd 452015 3 S 818-828


Dubiel Dawadschargal Ordemann Juumlrgen Pratschke Johann DubielWolfgang Naumann Michael

CAND1 exchange factor promotes Keap1 integration into cullin 3-RING ubiquitin ligaseduring adipogenesisIn International journal of biochemistry amp cell biology - Amsterdam Elsevier Bd662015 S 95-100


Schweitzer Katrin Naumann Michael

CSN-associated USP48 confers stability to nuclear NF-[kappa]BRelA by trimmingK48-linked Ub-chainsIn Biochimica et biophysica acta Molecular cell research - Amsterdam [ua]Elsevier Bd 18532015 2 S 453-469


Medunjanin Senad Daniel Jan-Marcus Weinert Soumlnke Dutzmann Jochen Burgbacher Frank Brecht Sarah Bruumlmmer Dennis Kaumlhne Thilo NaumannMichael Sedding Daniel Zuschratter Werner Braun-Dullaeus Ruediger C

DNA-dependent protein kinase (DNA-PK) permits vascular smooth muscle cell

proliferation through phosphorylation of the orphan nuclear receptor NOR1In Cardiovascular research - Oxford Oxford University Press Bd 1062015 3 S488-497


Reichenbach Nicole Herrmann Ulrike Kaumlhne Thilo Schicknick Horst Pielot Rainer Naumann Michael Dieterich Daniela C Gundelfinger EckartD Smalla Karl-Heinz Tischmeyer Wolfgang

Differential effects of dopamine signalling on long-term memory formation andconsolidation in rodent brainIn Proteome science PS - London BioMed Central Bd 132015 Art-Nr13 insges17 S


Dubiel Dawadschargal Rockel Beate Naumann Michael Dubiel Wolfgang

Diversity of COP9 signalosome structures and functional consequencesIn FEBS letters for the rapid publication of short reports in biochemistry biophysicsand molecular biology - Chichester Wiley Bd 5892015 19 PtA S 2507-2513


Wurm Rebecca Just Sissy Wang Xu Wex Katharina Schmid Ursula Blanchard Nicolas Waisman Ari Schild Hans-Joumlrg Naumann Michael Schluumlter Dirk Nishanth Gopala

Protective dendritic cell responses against listeriosis induced by the short form of thedeubiquitinating enzyme CYLD are inhibited by full-length CYLDIn European journal of immunology - Weinheim Wiley-VCH Bd 452015 5 S 1366-1376


Schmidt Joumlrn H Pietkiewicz Sabine Naumann Michael Lavrik Inna N

Quantification of CD95-induced apoptosis and NF-[Kappa]B activation at the single celllevelIn Journal of immunological methods JIM - Amsterdam [ua] Elsevier Science Bd4232015 S 12-17


Dorosz Susann A Ginolhac Aureacutelien Kaumlhne Thilo Naumann Michael Sauter Thomas Salsmann Alexandre Bueb Jean-Luc

Role of calprotectin as a modulator of the IL27-mediated proinflammatory effect onendothelial cellsIn Mediators of inflammation - Sylvania Ohio Hindawi Publishing Corp 2015 Art-ID737310 insges 16 S


Yazdi Samira Durdagi Serdar Naumann Michael Stein Matthias

Structural modeling of the N-terminal signal-receiving domain of I[kappa]B[alpha]In Frontiers in molecular biosciences - Lausanne Frontiers Bd 22015 Art-Nr 32insges 16 S


2014

Abstrakt

Schnoumlder Tina Pandey Akhilesh Datt Nimmagadda Subbaiah Chery WangXu Maubach Gunter Wolleschak Denise Naumann Michael Schluumlter Dirk Lane Steven W Mullally Ann Heidel Florian Fischer Thomas

JAK2V617F mutation is sufficient for autocrine induction of IP-10 in hematopoietic cellsIn Oncology research and treatment - Basel Karger Bd 372014 Suppl 5 V618 S199



Flassig Robert J Maubach Gunter Taumlger Christian Sundmacher Kai Naumann Michael

Experimental design validation and computational modeling uncover DNA damagesensing by DNA-PK and ATMIn Molecular BioSystems - Cambridge Royal Society of Chemistry Bd 102014 7 S1978-1986


Sokolova Olga Vieth Michael Gnad Thorsten Bozko Przemyslaw M Naumann Michael

Helicobacter pylori promotes eukaryotic protein translation by activatingphosphatidylinositol 3 kinasemTORIn International journal of biochemistry amp cell biology - Amsterdam Elsevier Bd552014 S 157-163


Sokolova Olga Maubach Gunter Naumann Michael

MEKK3 and TAK1 synergize to activate IKK complex in Helicobacter pylori infectionIn Biochimica et biophysica acta - Amsterdam [ua] ElsevierBiochimica etbiophysica acta Molecular cell research Bd 18432014 4 S 715-724


Dissertation

Borgmann Marc Naumann Michael [Gutachter]

Molekulare Charakterisierung der Interaktion des COP9-Signalosoms mit NF-[Kappa]BRelA und I[Kappa]BαIn Magdeburg Univ Fak fuumlr Naturwiss Diss 2014 102 Bl graph Darst

2013


Wang Xu Deckert Martina Xuan Nguyen Thi Nishanth Gopala Just Sissy Waisman Ari Naumann Michael Schluumlter Dirk

Astrocytic A20 ameliorates experimental autoimmune encephalomyelitis by inhibitingNF-[kappa]B- and STAT1-dependent chemokine production in astrocytesIn Acta neuropathologica - Berlin Springer Bd 1262013 5 S 711-724


Dubiel Dawadschargal Gierisch Maria Elka Huang Xiaohua DubielWolfgang Naumann Michael

CAND1-dependent control of cullin 1-RING Ub ligases is essential for adipogenesisIn Biochimica et biophysica acta - Amsterdam [ua] Elsevier Bd 18332013 5 S1078-1084


Maubach Gunter Sokolova Olga Wolfien Markus Rothkoumltter Hermann-Josef Naumann Michael

Ca2+calmodulin-dependent kinase II contributes to inhibitor of nuclear factor-kappa Bkinase complex activation in Helicobacter pylori infectionIn International journal of cancer - Malden Mass Wiley-Blackwell Bd 1332013 6S 1507-1512


Lee Jung-Hoon Yi Lina Li Jixi Schweitzer Katrin Borgmann Marc Naumann Michael Wu Hao

Crystal structure and versatile functional roles of the COP9 signalosome subunit 1In Proceedings of the National Academy of Sciences of the United States of America- Washington DC NAS Bd 1102013 29 S 11845-11850


Karpova Anna Mikhaylova Marina Bera Sujoy Baumlr Julia Reddy PashamParameshwar Behnisch Thomas Rankovic Vladan Spilker Christina Bethge Philipp Sahin Jale Kaushik Rahul Zuschratter Werner KaumlhneThilo Naumann Michael Gundelfinger Eckart D Kreutz Michael R

Encoding and transducing the synaptic or extrasynaptic origin of NMDA receptorsignals to the nucleusIn Cell - Cambridge Mass Cell Press Bd 1522013 5 S 1119-1133


Sokolova Olga Borgmann Marc Rieke Cornelia Schweitzer Katrin Rothkoumltter Hermann-Josef Naumann Michael

Helicobacter pylori induces type 4 secretion system-dependent but CagA-independentactivation of I[kappa]Bs and NF-[kappa]BRelA at early time pointsIn International journal of medical microbiology - Muumlnchen Elsevier Bd 30320138 S 548-552


Sokolova Olga Vieth Michael Naumann Michael

Protein kinase C isozymes regulate matrix metalloproteinase-1 expression and cellinvasion in Helicobacter pylori infectionIn Gut - London BMJ Publishing Group Bd 622013 3 S 358-367


Diesing Anne-Kathrin Nossol Constanze Faber-Zuschratter Heidi Zuschratter Werner Renner Lydia Sokolova Olga Naumann Michael Rothkoumltter Hermann-Josef

Rapid interaction of Helicobacter pylori with microvilli of the polar human gastricepithelial cell line NCI-N87In The anatomical record - Hoboken NJ Wiley-Liss Bd 2962013 12 S 1800-1805



Rapid interaction of Helicobacter pylori with microvilli of the polar human gastricepithelial cell line NCI-N87In The anatomical record - Hoboken NJ Wiley-Liss Bd 2962013 12 S C1


Originalartikel in begutachteter internationaler Zeitschrift

Nishanth Gopala Deckert Martina Wex Katharina Massoumi Ramin Schweitzer Katrin Naumann Michael Schluumlter Dirk

CYLD enhances severe listeriosis by impairing IL-6STAT3-dependent fibrin productionIn PLoS pathogens - Lawrence Kan PLoS Bd 92013 6 Art e1003455 insges 17S


2012


Buss Holger Handschick Katja Jurrmann Nadine Pekkonen Pirita Beuerlein Knut Muumlller Helmut Wait Robin Saklatvala Jeremy Ojala PaumliviM Schmitz M Lienhard Naumann Michael Kracht Michael

Cyclin-dependent kinase 6 phosphorylates NF-[kappa]B p65 at serine 536 andcontributes to the regulation of inflammatory gene expressionIn PLoS one - Lawrence Kan PLoS Bd 72012 12 insges 13 S


Kaumlhne Thilo Kolodziej Angela Smalla Karl-Heinz Eisenschmidt Elke HausUtz-Uwe Weismantel Robert Kropf Siegfried Wetzel Wolfram Ohl FrankW Tischmeyer Wolfgang Naumann Michael Gundelfinger Eckart D

Synaptic proteome changes in mouse brain regions upon auditory discriminationlearningIn Proteomics - Weinheim Wiley-Blackwell Bd 122012 1516 S 2433-2444


2011


Naumann Michael

Therapierelevante Forschung in der Inneren MedizinIn Aumlrzteblatt Sachsen-Anhalt - Magdeburg Aumlrztekammer Sachsen-Anhalt Bd222011 4 S 25-26



Rieke Cornelia Papendieck Anja Sokolova Olga Naumann Michael

Helicobacter pylori-induced tyrosine phosphorylation of IKK[beta] contributes to NF-[kappa]B activationIn Biological chemistry - Berlin [ua] de Gruyter Bd 3922011 4 S 387-393


Neish Andrew S Naumann Michael

Microbial-induced immunomodulation by targeting the NF-[Kappa]B systemIn Trends in microbiology - Cambridge Elsevier Bd 192011 12 S 596-605


2010



Control of NF-[kappa]B activation by the COP9 signalosomeIn Biochemical Society Biochemical Society transactions - London Portland PrBd 382010 1 S 156-161


Cama Gianluca Jacobs Thomas Dimaki Maria I Svendsen Winnie E Hauptmann Peter Naumann Michael

Disposable micro-fluidic biosensor array for online parallelized cell adhesion kineticsanalysis on quartz crystal resonatorsIn Measurement science and technology - Bristol IOP Publ Ltd Bd 212010 8insges 12 S


Rollieacute Sascha Lendeckel Uwe Naumann Michael Reichl Udo SundmacherKai

Dynamics of bionanoparticle targeting in mixtures of human tumour cells by validatedpopulation balance modellingIn Soft matter - Cambridge RSC Publ Bd 62010 6 S 1203-1216


Schweitzer Katrin Sokolova Olga Bozko Przemyslaw M Naumann Michael

Helicobacter pylori induces NF-[kappa]B independent of CagA CorrespondenceIn European Molecular Biology Organization EMBO reports - London Nature PublGroup Bd 112010 1 S 10-11


Gnad Thorsten Feoktistova Maria Leverkus Martin Lendeckel Uwe Naumann Michael

Helicobacter pylori-induced activation of [beta]-catenin involves low density lipoproteinreceptor-related protein 6 and dishevelledIn Molecular cancer - London Biomed Central Bd 92010 31 insges 9 S


Wex Thomas Leodolter Andreas Bornschein Jan Kuumlster Doumlrthe KaumlhneThilo Kropf Siegfried Albrecht Caroline Naumann Michael RoessnerAlbert Malfertheiner Peter

Interleukin 1 beta (IL1B) gene polymorphisms are not associated with gastriccarcinogenesis in GermanyIn Anticancer research - Kapandriti International Inst of Anticancer Research Bd302010 2 S 505-511


Rieke Cornelia Kaumlhne Thilo Schweitzer Katrin Schraven Burkhart Wienands Juumlrgen Engelke Michael Naumann Michael

Non-T cell activation linker regulates ERK activation in Helicobacter pylori-infectedepithelial cellsIn Cellular signalling - Amsterdam Elsevier Bd 222010 3 S 395-403


Mirastschijski Ursula Schnabel Reinhild Naumann Michael Kaumlhne Thilo

Novel plant metalloproteinase from Dieffenbachia seguine causes fingertip necrosisCorrespondenceIn The British journal of dermatology - Oxford Wiley-Blackwell Bd 1622010 5 S1150-1152


Nishanth Gopala Sakowicz-Burkiewicz Monika Haumlndel Ulrike KlicheStefanie Wang Xiaoqian Naumann Michael Deckert Martina Schluumlter Dirk

Protective toxoplasma gondii-specific T-cell responses require T-cell-specificexpression of protein kinase C-thetaIn Infection and immunity - Washington DC Soc Bd 782010 8 S 3454-3464


Valero Teresa Moschopoulou Georgia Kintzios Spiridon HauptmannPeter Naumann Michael Jacobs Thomas

Studies on neuronal differentiation and signalling processes with a novel impedimetricbiosensorIn Biosensors amp bioelectronics - Barking Essex Elsevier Bd 262010 4 S 1407-1413


Backert Steffen Naumann Michael

What a disorder proinflammatory signaling pathways induced by Helicobacter pyloriIn Trends in microbiology - Cambridge Elsevier Bd 182010 11 S 479-486


2009


Heidel Florian Lipka Daniel Mirea Fian K Mahboobi Siavosh GrundlerRebekka Kancha Rama K Duyster Justus Naumann Michael HuberChristoph Boumlhmer Frank D Fischer Thomas

Bis(1H-indol-2-yl)methanones are effective inhibitors of FLT3-ITD tyrosine kinase andpartially overcome resistance to PKC412A in vitroIn British journal of haematology - Oxford [ua] Wiley-Blackwell Bd 1442009 6 S865-874


Welteke Verena Eitelhuber Andrea Duumlwel Michael Schweitzer Katrin Naumann Michael Krappmann Daniel

COP9 signalosome controls the Carma1-Bcl10-Malt1 complex upon T-cell stimulationIn European Molecular Biology Organization EMBO reports - London Nature PublGroup Bd 102009 6 S 642-648


Schirrmeister Wiebke Gnad Thorsten Wex Thomas Higashiyama Shigeki Wolke Carmen Naumann Michael Lendeckel Uwe

Ectodomain shedding of E-cadherin and c-Met is induced by Helicobacter pyloriinfectionIn Experimental cell research - San Diego Calif Elsevier Bd 3152009 20 S3500-3508


Valero Teresa Jacobs Thomas Moschopoulou Georgia Naumann Michael Hauptmann Peter Kintzios Spiridon

Electrical impedance analysis of N2a neuroblastoma cells in gel matrices after ACh-receptor triggering with an impedimetric biosensorIn Procedia chemistry - Amsterdam [ua] Elsevier Bd 12009 1 S 734-737


Jacobs Thomas Valero Teresa Naumann Michael Kintzios Spiridon Hauptmann Peter

Electrical impedance spectroscopy of gel embedded neuronal cells based on a novelimpedimetric biosensorIn Procedia chemistry - Amsterdam [ua] Elsevier Bd 12009 1 S 261-264


Walduck Anna K Weber Matthias Wunder Christian Juumlttner Stefan StolteManfred Vieth Michael Wiedenmann Bertram Meyer Thomas F NaumannMichael Houmlcker Michael

Identification of novel Cyclooxygenase-2-dependent genes in Helicobacter pyloriinfection in vivoIn Molecular cancer - London Biomed Central Bd 82009 22 insges 13 S


Jacobs Thomas Cama Gianluca Bolaeva Kermen Naumann Michael Hauptmann Peter

Impact of flow-through regime on the cultivation of epithelial cells on quartz crystalresonators in micro fluidic channelsIn Procedia chemistry - Amsterdam [ua] Elsevier Bd 12009 1 S 365-368


Cama Gianluca Bolaeva Kermen Jacobs Thomas Hartmann Matthias Hirsch Soumlren Naumann Michael Hauptmann Peter

Influence of statistical variations in cell distribution on the proliferation kinetics ofMadin-Darby canine kidney cells on quartz crystal resonatorIn Procedia chemistry - Amsterdam [ua] Elsevier Bd 12009 1 S 373-376


Poltz Rainer Franke Raimo Schweitzer Katrin Klamt Steffen Gilles Ernst-Dieter Naumann Michael

Logical network of genotoxic stress-induced NF-[kappa]B signal transduction predictsputative target structures for therapeutic intervention strategiesIn Advances and applications in bioinformatics and chemistry - Albany Auckland Dove Medical Press Bd 22009 S 125-138


Originalartikel in begutachteter zeitschriftenartiger Reihe


Impedimetric biosensor system for the on-line analysis of stimulated neuronal cellsembedded in gel matricesIn IEEE Sensors 2009 - IEEE ISBN 978-1-424-45335-1 S 1864-1867 KongressIEEE Conference on Sensors 8 (Christchurch) 20091025-28 [Auch auf CD-ROMerschienen]

2008


Xia Guoqing Schneider-Stock Regine Diestel Antje Habold Caroline Kruumlger Sabine Roessner Albert Naumann Michael Lendeckel Uwe

Helicobacter pylori regulates p21WAF1 by histone H4 acetylationIn Biochemical and biophysical research communications - San Diego Calif Elsevier ISSN 0006-291x Bd 3692008 2 S 526-531


Sokolova Olga Bozko Przemyslaw M Naumann Michael

Helicobacter pylori suppresses glycogen synthase kinase 3[beta] to promote [beta]-catenin activityIn The journal of biological chemistry - Bethesda Md ASBMB Bd 2832008 43 S29367-29374


Franke Raimo Muumlller Melanie Wundrack Nicole Gilles Ernst-Dieter Klamt

Steffen Kaumlhne Thilo Naumann Michael

Host-pathogen systems biology logical modelling of hepatocyte growth factor andHelicobacter pylori induced c-Met signal transductionIn BMC systems biology - London BioMed Central Bd 22008 4 insges 17 S


Sakowicz-Burkiewicz Monika Nishanth Gopala Helmuth Ulrike DroumlgemuumlllerKatrin Busch Dirk H Utermoumlhlen Olaf Naumann Michael Deckert Martina Schluumlter Dirk

Protein kinase C-[theta] critically regulates the proliferation and survival of pathogen-specific T cells in murine listeriosisIn The journal of immunology - Bethesda Md American Assoc of ImmunologistsBd 1802008 8 S 5601-5612



Jacobs Thomas Cama Gianluca Hartmann Matthias Kaumlhne Thilo HirschSoumlren Naumann Michael Hauptmann Peter

Disposable micro fluidic biosensor array for parallelized online cell stimulation analysisIn Proceedings Eurosensors XXII - Duumlsseldorf VDIVDE-Ges Mess- undAutomatisierungstechnik S 1189-1192 2008 Kongress Eurosensors 22 (Dresden) 20080907-10[Beitrag auf CD-ROM]


Micro fluidic biosensor array for parallelized cell adhesion analysis during pathogenicinfectionIn IEEE sensors 2008 S 1460-1463 Kongress IEEE Conference on Sensors 7(Lecce Italy) 20081026-29[Beitrag auf CD-ROM]

Jacobs Thomas Bolaeva Kermen Kaumlhne Thilo Naumann Michael Hauptmann Peter

Online adhesion analysis of hepatocyte growth factor stimulated cells with resonantbiosensorIn Proceedings Eurosensors XXII - Duumlsseldorf VDIVDE-Ges Mess- undAutomatisierungstechnik ISBN 978-3-00-025217-4 S 1185-1188 2008 KongressEurosensors 22 (Dresden) 20080907-10


Real-time analysis of hepatocyte growth factor induced cell motility with quartz crystalresonators

In IEEE sensors 2008 the 7th IEEE Conference on Sensors Lecce Italy October26-29 2008 S 246-249 Kongress IEEE Conference on Sensors 7 (Lecce Italy) 20081026-29[Beitrag auf CD-ROM]

2007

Buchbeitrag

Wex Thomas Sokic-Milutinovic Aleksandra Kalinski Thomas RoessnerAlbert Malfertheiner Peter Naumann Michael Lendeckel Uwe

Expression of ADAM19 in Helicobacter pylori-mediated diseases and gastric cancerIn Gastric cancer research trends - New York Nova Science ISBN 978-1-600-21725-8 S 171-188 2007


Neumann Manfred Naumann Michael

Beyond I[kappa]Bs alternative regulation of NF-[kappa]B activityIn Federation of American Societies for Experimental Biology The FASEB journal -Bethesda Md FASEB Bd 212007 11 S 2642-2654


Schweitzer Katrin Bozko Przemyslaw M Dubiel Wolfgang NaumannMichael

CSN controls NF-[kappa]B by deubiquitinylation of I[kappa]B[alpha]In European Molecular Biology Organization The EMBO journal - London NaturePubl Group Bd 262007 6 S 1532-1541


Bimczok Diane Rau Henriette Wundrack Nicole Naumann Michael Rothkoumltter Hermann-Josef McCullough Kenneth Summerfield Artur

Cholera toxin promotes the generation of semi-mature porcine monocyte-deriveddendritic cells that are unable to stimulate T cellsIn Veterinary research - Paris EdScientifiques Elsevier Bd 382007 4 S 597-612


Naumann Michael

Control of the NF-[kappa]B inhibitor I[kappa]B[alpha] in pathogen infectionIn Biochemical Society Biochemical Society transactions - London Portland PrBd 352007 2 S 267-269


Bank Ute Tadje Janine Taumlger Michael Wolke Carmen Bukowska Alicja Ittenson Annelore Reinhold Dirk Helmuth Martin Ansorge Siegfried

Shakespeare Ann Vieth Michael Malfertheiner Peter Naumann Michael Lendeckel Uwe

Inhibition of alanyl-aminopeptidase on CD4+CD25+ regulatory T-cells enhancesexpression of FoxP3 and TGF-[beta]1 and ameliorates acute colitis in miceIn International journal of molecular medicine - Athens Bd 202007 4 S 483-492


Lippert E Falk W Bataille F Kaumlhne Thilo Naumann Michael Goeke M Herfarth H Schoelmerich J Rogler G

Soluble galectin-3 is a strong colonic epithelial-cell-derived lamina propria fibroblast-stimulating factorIn Gut - London BMJ Publishing Group Bd 562007 1 S 43-51


Stork Bjoumlrn Neumann Konstantin Goldbeck Ingo Alers Sebastian KaumlhneThilo Naumann Michael Engelke Michael Wienands Juumlrgen

Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity ofCa2+ signaling in B cellsIn European Molecular Biology Organization The EMBO journal - London NaturePubl Group Bd 262007 4 S 1140-1149


Bimczok Diane Doumlll Susanne Rau Henriette Goyarts Tanja WundrackNicole Naumann Michael Daumlnicke Sven Rothkoumltter Hermann-Josef

The Fusarium toxin deoxynivalenol disrupts phenotype and function of monocyte-derived dendritic cells in vivo and in vitroIn Immunobiology - Amsterdam Elsevier Bd 2122007 8 S 655-666



Jacobs Thomas Gomide Andreza Kaumlhne Thilo Kienle Achim NaumannMichael Hauptmann Peter

Micro fluidic biosensor system based on quartz crystal resonators for fast onlineadherent cell proliferation and stimulation analysisIn IEEE sensors 2007 conference S 720-723

2006


Crabtree Jean E Naumann Michael

Epithelial cell signaling in Helicobacter pylori infection

In Current signal transduction therapy - San Francisco Calif [ua] BenthamScience Publ Bd 12006 1 S 53-65


Kruumlger Sabine Hundertmark Tanja Kalinski Thomas Peitz Ulrich WexThomas Malfertheiner Peter Naumann Michael Roessner Albert

Helicobacter pylori encoding the pathogenicity island activates matrix-metalloproteinase 1 in gastric epithelial cells via JNK and ERKIn The journal of biological chemistry - Bethesda Md ASBMB Bd 2812006 5 S2868-2875


Neumann Manfred Foryst-Ludwig Anna Klar Stefanie Schweitzer Katrin Naumann Michael

The PAK1 autoregulatory domain is required for interaction with NIK in Helicobacterpylori-induced NF-[kappa]B activationIn Biological chemistry - Berlin [ua] de Gruyter Bd 3872006 1 S 79-86


2005

Buchbeitrag

Naumann Michael Crabtree J (ext)

Helicobacter pylori mechanisms for inducing epithelial cell proliferationIn Lax A (Ed) Bacterial protein toxins role in the interference with cell growthregulation Cambridge New York Cambridge Univ Press 2005 S 169 - 198(Advances in molecular and cellular microbiology 7)


Huang X (ext) Hetfeld B (ext) Seifert U (ext) Kaehne Thilo KloetzelPM (ext) Naumann Michael Bech-Otschir D (ext) Dubiel W (ext)

Consequences of COP9 signalosome and 26S proteasome interactionIn FEBS J 272(2005) Nr 15 S 3909 - 3917

Drynda Andreas Quax P (ext) Neumann Manfred Laan Wvan der (ext) Pap Geza Drynda Susanne Meinecke I (ext) Kekow Joern Neumann W(ext) Huizinga T (ext) Naumann Michael Koenig Wolfgang Pap T (ext)

Gene transfer of tissue inhibitor of metalloproteinases-3 reverses the inhibitory effectsof TNF-alpha on Fas-induced apoptosis in rheumatoid arthritis synovial fibroblastsIn J Immunol 174(2005) Nr 10 S 6524 - 6531

Malfertheiner Peter Sipponen P (ext) Naumann Michael Moayyedi P

(ext) Megraud F (ext) Xiao SD (ext)

Helicobacter pylori eradication has the potential to prevent gastric cancer a state-of-the- art critiqueIn Am J Gastroenterol 100(2005) Nr 9 S 2100 - 2115

Hollenbach Eike Vieth Michael WR Roessner Albert Neumann Manfred Malfertheiner Peter Naumann Michael

Inhibition of RICKnuclear factor-kappaB and p38 signaling attenuates theinflammatory response in a murine model of Crohn diseaseIn J Biol Chem 280(2005) Nr 15 S 14981 - 14988

Naumann Michael

Pathogenicity island-dependent effects of Helicobacter pylori on intracellular signaltransduction in epithelial cellsIn Int J Med Microbiol 295(2005) Nr 5 S 335 - 341

Wessler S (ext) Muenzner P (ext) Meyer T (ext) Naumann Michael

The anti-inflammatory compound curcumin inhibits Neisseria gonorrhoeae-induced NF-kappaB signaling release of pro-inflammatory cytokineschemokines and attenuatesadhesion in late infectionIn Biol Chem 386(2005) Nr 5 S 481 - 490

Krueger Sabine Kalinski Thomas Hundertmark Tanja Wex Thomas Kuester Doerthe Peitz Ulrich Ebert Matthias Naegler D (ext) Kellner U(ext) Malfertheiner Peter Naumann Michael Roecken Christoph RoessnerAlbert

Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancerIn J Pathol 207(2005) Nr 1 S 32 - 42

2004


Al-Ghoul L Wessler Silja Hundertmark Tanja Krueger Sabine Fischer W(ext) Wunder C (ext) Haas R (ext) Roessner Albert Naumann Michael

Analysis of the type IV secretion system-dependent cell motility of Helicobacter pylori-infected epithelial cellsIn Biochem Biophys Res Commun 322(2004) Nr 3 S 860 - 866

Foryst-Ludwig Anna Neumann Manfred Schneider-Brachert W (ext) Naumann Michael

Curcumin blocks NF-kappaB and the motogenic response in Helicobacter pylori-

infected epithelial cellsIn Biochem Biophys Res Commun 316(2004) Nr 4 S 1065 - 1072


Helicobacter pylori-induced epithelial cell signalling in gastric carcinogenesisIn Trends Microbiol 12(2004) Nr 1 S 29 - 36

Hollenbach Eike Neumann Manfred Vieth Michael WR Roessner Albert Malfertheiner Peter Naumann Michael

Inhibition of p38 MAP kinase- and RICKNF-kappaB-signaling suppressesinflammatory bowel diseaseIn Faseb J 18(2004) S 1550 - 1552

Leodolter Andreas Naumann Michael Malfertheiner Peter

Prevention of gastric cancer by Helicobacter pylori eradicationIn Dig Dis 22(2004) Nr 4 S 313 - 319

2003


Zhou C (ext) Wee S (ext) Rhee E (ext) Naumann Michael Dubiel W(ext) Wolf D (ext)

Fission yeast COP9signalosome suppresses cullin activity through recruitment of thedeubiquitylating enzyme Ubp12pIn Mol Cell 11(2003) S 927 - 938

Churin Y (ext) Al-Ghoul L Kepp O (ext) Meyer T (ext) Birchmeier W(ext) Naumann Michael

Helicobacter pylori CagA protein targets the c-Met receptor and enhances themotogenic responseIn J Cell Biol 161(2003) Nr 2 S 249 - 255

Juettner S (ext) Cramer T (ext) Wessler Silja Walduck A (ext) Naumann Michael Hoecker M (ext)

Helicobacter pylori stimulates host cyclooxygenase-2 gene transcription criticalimportance of MEKERK-dependent activation of USF1-2 and CREB transcriptionfactorsIn Cell Microbiol 5(2003) Nr 11 S 821 - 834

Strowski M (ext) Cramer T (ext) Schaefer G (ext) Wessler Silja Naumann Michael Hoecker M (ext)

Helicobacter pylori stimulates host vascular endothelial growth factor-A (vegf-A) geneexpression via MEKERK-dependent activation of Sp1 and Sp3 - Gedr ersch inFASEB J 18(2004)1 S 218 - 220In Faseb J(2003)

Hollenbach Eike Naumann Michael Malfertheiner Peter

The mitogen-activated protein kinase p38 a new molecular target for anti-inflammatory therapy in Crohns diseaseIn Gastroenterol Polska 10(2003) Nr 4 S 335 - 340

2002


Gerhard M (ext) Rad R (ext) Prinz C (ext) Naumann Michael

Pathogenesis of Helicobacter pylori infectionIn Helicobacter 7(2002) Suppl 1 S 17 - 23

KooperationenProfilZellbiologie

Zellulaumlre Infektionsbiologie Helicobacter pyloriMagenkrebs PraumlventionsforschungMultiproteinkomplex (COP9)

ServiceBeratung Gutachten Projekte zum Themenfeld


VitapresseDas Institut kooperiert mit den Kliniken des Zentrums fuumlr Innere Medizin in Lehre undForschung Die Studierenden werden in den Studiengaumlngen Medizin und Biosystems-Engineering ausgebildet Das Forschungsprogramm des Instituts umfasstwissenschaftliche Projekte zur Pathophysiologie von Entzuumlndungen und TumorbiologieHier sind die molekularen und zellbiologische Mechanismen der intrazellulaumlrenSignaluumlbertragung von besonderem Interesse Daruumlber hinaus arbeiten die Arbeitsgruppenauf die Frage der Funktion von Proteinen in zellulaumlren Netzwerken und dem innovativenAnsatz von mathematischen Modellen des Signals Prozesse in komplexen Systemen

Prof Dr rer nat Michael Naumann

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NaumannmedovgudeHomepageProjekte

Aktuelle Projekte

Maladaptive processes across physiological barriers in chronic diseasesLaufzeit 01102018 - 31032023

Helicobacter pylori type IV secretion system-directed membrane-proximal NF-kBsignalingLaufzeit 01012018 - 31122021

Plasticity and cell-type specific functions of OTUB1 in infectionLaufzeit 01012018 - 31122021

ZIKAlliance Project 53Laufzeit 01102016 - 30092020


Immunregulatory function of the deubiquitinylating enzymes A20 and OTUB1 ininfectious and autoimmune diseasesLaufzeit 01012014 - 31122017

E3 Ubiquitin Ligase-abhaumlngige NF-kB Regulation in der Helicobacter pylori InfektionLaufzeit 01012014 - 31122017

Identifizierung neuer Zielmolekuumlle fuumlr die klinische Therapie der akuten myeloischenLeukaumlmieLaufzeit 01062014 - 31052017


NF-kB Regulation in der Helicobacter InfektionLaufzeit 01012010 - 31122013

Immunregulatorische Funktion von Deubiquitinylasen bei der ToxoplasmoseLaufzeit 01012010 - 31122013

MODEXALaufzeit 01092009 - 31082012

Nedd8COP9 Signalosom-abhaumlngige Kontrolle von IkBs und RelALaufzeit 01102008 - 31082012




















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2013



2012


2011



2010


2009



2008



2007

Buchbeitrag



2006


2005

Buchbeitrag


2004


2003


2002










2005

Buchbeitrag













Naumann Michael






2004













2003












2002










Aktuelle Projekte


2019

Abstrakt


2018


2017

Abstrakt


2016

Abstrakt



2015

Abstrakt


2014

Abstrakt


Dissertation

2013



2012


2011



2010


2009



2008



2007

Buchbeitrag



2006


2005

Buchbeitrag


2004


2003


2002






Naumann Michael






2004













2003












2002










Aktuelle Projekte


2019

Abstrakt


2018


2017

Abstrakt


2016

Abstrakt



2015

Abstrakt


2014

Abstrakt


Dissertation

2013



2012


2011



2010


2009



2008



2007

Buchbeitrag



2006


2005

Buchbeitrag


2004


2003


2002









2003












2002










Aktuelle Projekte


2019

Abstrakt


2018


2017

Abstrakt


2016

Abstrakt



2015

Abstrakt


2014

Abstrakt


Dissertation

2013



2012


2011



2010


2009



2008



2007

Buchbeitrag



2006


2005

Buchbeitrag


2004


2003


2002





2002










Aktuelle Projekte


2019

Abstrakt


2018


2017

Abstrakt


2016

Abstrakt



2015

Abstrakt


2014

Abstrakt


Dissertation

2013



2012


2011



2010


2009



2008



2007

Buchbeitrag



2006


2005

Buchbeitrag


2004


2003


2002


Untersuchungelastisch-plastischerDeformationen · III-IDDDD c) Bild 5 zeigt, daß ﬁir...

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