Update zur Diagnose und Therapie von Uterusinvolutionsstörungen

Axel Wehrend

Klinikum Veterinärmedizin - Klinik für Geburtshilfe, Gynäkologie und Andrologie der Groß- und Kleintiere mit Tierärztlicher Ambulanz der JLU

Gießen

KlinikumVeterinärmedizin

- Uterusinvolution

- Problem der Uterusinvolutionsstörung

- Diagnostik

- Therapie

Puerperium Anforderungen an die Kuh

- Laktation- Brutpflegeverhalten (Mutterkuhhaltung)- Fütterungsumstellung- „sozialer Stress“ (Umstallung u. a.)- endokrine Umstellung- Involution der Geschlechtsorgane- Anlaufen der Ovarfunktion

Metabolische, soziale und immunologische Leistung

„Sozialer“ Stress- Tiere werden um den Geburtszeitraum häufig mehrmals aus

ihrem sozialem Gefüge gerissen und in neue Gruppe integriert.

Trockenstehergruppe Abkalbebereich Laktierende Gruppe

- signifikanter Zusammenhang zwischen hierarchischer Stellung und Krankheitshäufigkeit

- trifft vor allem Tiere, die zum ersten Mal abkalben

Was passiert im Puerperium?

1. Tag

4. Tag

8. Tag

21. Tag

Phasen der deutlichen

Tonisierung

1. – 3. Tag

ab 10. – 14. Tag

Grunert, 1993

VorführenderPräsentationsnotizenAtonia uteri als Früerkennung

Reorganisation des Zervikalkanales bei zehn Kühen

Was passiert im Puerperium?

VorführenderPräsentationsnotizenBis zu 20 % Verlust – Meeressäuger bis zu 40 %

Was passiert im Puerperium?

Zaremba, 1990„Alte“ zeitliche Angaben zur Dauer der Involution sind nach wie vor gültig.Milchkuh: 42 – 50 Tage, Mutterkuh: 30 – 35 Tage

VorführenderPräsentationsnotizenWoran liegt die kurze Involution?

Involutionsstörungen des UterusElimination der Erreger

innerhalb von 2 - 6 Wochen

„sterile“ GebärmutterInfektion der Gebärmutter

Besiedlung der Gebärmutter mit

Erregern in/nach der Geburt

VorführenderPräsentationsnotizenWoran liegt die kurze Involution?

Involutionsstörungen des Uterus

- Adaptation an die Umgebung- metabolische Komponente- sozialer Stress (Mensch und Tier)- Krankheiten- Erblichkeitsfaktor- Hitzestress

Kontraktilität der Gebärmutter

Erregerart und -menge

- metabolische Komponente(Ketose, Azidose, Kalzium,Selen)

- Bewegung- Verletzungen

- Was?- Wann?- Wie viel?

Abwehrleistung der Kuh

VorführenderPräsentationsnotizenWoran liegt die kurze Involution?

Involutionsstörungen des Uterus

Negativer Einfluss auf Funktion der Neutrophilen Granulozyten

- Lipolyse- Anstieg der NEFA-Konzentration- niedrige intrazelluläre Glykogenreserven

- Erregerelimination:initial von den Neutrophilen Granulozyten getragen

Signifikante Unterschiede in der Neutrophilenfunktion schon vor der Geburt bzw. vor der Uteropathie (Hammon et al., 2006)

VorführenderPräsentationsnotizenWoran liegt die kurze Involution?

Nachgeburts-verhaltung

Metritis Endometritis- Klinische Endometritis- Subklinische Endometritis< 21. Tage p. p.

> 21. Tage p. p.

Involutionsstörungen des Uterus

Krankheitsbild Anzahl Tiere Kühe gesamt (513) Kranke Kühe (247)

Metritis puerperalis 93 18,1 37,7

Klinische Mastitis 87 17,0 35,2

Retentio secundinarum 69 13,5 27,9

Hochgradige Lahmheit 20 3,9 8,1

Gebärparese 20 3,9 8,1

Labmagenverlagerung 18 3,5 7,3

Klinische Ketose 14 2,7 5,7

Pneumonie 11 2,1 4,5

Absolute und relative Häufigkeit von Puerperalerkrankungen in den ersten 13Tagen post partum bei Milchkühen (n = 513)

- 10 – 20 % entwickeln eine Metritis- 10 – 30 % entwickeln eine Endometritis

LeBlanc, 2012

Involutionsstörungen des Uterus

Involutionsstörungen des Uterus

Möglichkeiten:- Keine tierärztliche Untersuchung- Transrektale Palpation- Sonographie- Vaginale Untersuchung (Vaginoskopie,

manuelle Untersuchung, Hilfsgeräte) - Uterustupferprobenentnahme- Zytologie- Neue Labormethoden / Schnelltest

- Sensitivität und Spezifität- Definition der Erkrankung- Hier: auf Einzeltierebene

Diagnostik

Wie wird eine Untersuchung durchgeführt?Metritis:- Hehenberger et al. (2015):- vaginale Untersuchung 94,3 % (116/ 123)

- meist behandschuhte Hand- Metricheck sehr selten: 97 % nie- Spekulum von ca. 10 %

- rektale Untersuchung: 83,7%- Weitere Untersuchung: bei 69,1 %- Espadamala et al. (2018):

- 70 % transrektale Palpation + Ausfluss (33 Farmen)- 24 % nur Ausfluss

Diagnostik

Aus dem Gerichtssaal

Diagnostik

- Erfolgte die Behandlung der Nachgeburtsverhaltungkunstgerecht?

- Hätte eine Allgemeinuntersuchung der Kuh durchgeführtwerden müssen?

- Hätte eine Euteruntersuchung der Kuh durchgeführt werdenmüssen?

- Mit welcher Wahrscheinlichkeit hätte die Euterentzündungmit Erfolg behandelt werden können, wenn sie bereits amxxx entdeckt worden wäre?

Keine tierärztliche Untersuchung- Sinnvoll um verdächtige Tiere zu detektieren

- Einbindung / Aufgabe des Tierhalters- Weiterentwicklung durch Automatisierung und Digitalisierung

(Milchtemperatur, Aktivität, Gewicht, Futteraufnahme, Gewicht, u.a.)

- Durch bestimmte Glykane in der Milch kann eine Nachgeburtsverhaltung detektiert werden

Diagnostik

VorführenderPräsentationsnotizenGlykane: Mehrfachzucker

Diagnostik

Anzahl klinisch gesunder Milchkühe mit einer rektal gemessenen Körperinnentemperatur von mehr als 39,6 °C (81 Kühe von 266) im Frühpuerperium

Diagramm1

24

45

31

27

18

15

13

13

13

5

Tag post partum

Anzahl Tiere

errechnen Grenzw.

Stallnr.Tag partus012345678910

2514.3.39.139.839.939.439.839.739.439.439.238.939.0

4920.4.39.839.640.140.139.939.539.239.539.539.239.4

51026.6.39.140.140.340.239.739.739.339.539.138.939.1

81614.4.39.739.439.840.239.439.339.039.439.139.239.1

9181.4.39.038.638.638.838.738.938.638.838.838.438.9

101920.5.38.838.838.639.138.838.838.639.038.538.8

12202.7.38.838.939.038.838.838.739.038.739.038.7

142211.5.38.838.738.738.839.139.339.139.139.439.239.2

184310.3.39.138.738.738.838.738.738.938.840.238.6

194613.3.38.939.039.039.539.239.238.939.239.238.9

21503.4.39.138.939.038.938.538.738.738.638.838.938.9

235824.6.38.838.638.839.039.039.039.038.938.738.7

276412.7.38.738.839.539.940.240.139.739.539.439.539.3

286826.7.39.138.638.938.938.939.039.438.839.339.039.4

296925.6.39.339.339.539.238.939.339.239.339.138.939.0

307129.7.39.139.739.739.439.539.039.639.139.139.339.2

338129.5.39.039.338.939.039.039.439.239.239.139.1

348413.4.38.738.940.239.640.339.639.239.239.339.239.0

358819.6.39.338.738.738.938.939.038.938.839.039.038.9

36956.6.39.338.738.938.939.339.739.138.838.838.9

3710022.6.38.838.739.139.339.038.938.838.839.138.9

381035.6.39.339.139.239.338.939.039.239.239.038.739.0

431202.8.39.338.838.739.038.939.138.839.439.238.939.0

4412118.4.39.239.038.739.139.039.039.339.038.838.838.7

4612516.4.39.639.839.039.139.139.339.239.239.239.139.4

4712716.6.40.039.139.640.240.039.439.639.339.239.138.8

4812818.4.39.540.539.839.839.439.439.139.139.039.1

4912925.6.39.038.738.739.039.239.039.239.239.239.339.2

5414918.7.38.938.938.938.639.139.439.539.439.238.738.8

5515211.6.38.838.739.039.338.839.039.139.139.038.639.1

611658.6.38.738.939.238.738.638.638.838.938.838.6

6216714.6.38.938.638.538.639.039.039.239.039.538.939.2

631682.4.39.138.639.439.439.139.239.439.439.339.439.3

6416917.6.38.839.939.139.039.539.438.939.339.539.939.4

701755.4.39.039.139.039.640.139.839.939.839.639.339.5

7117625.5.38.839.039.039.439.839.339.439.038.938.738.9

7317720.7.38.838.738.939.039.239.539.039.039.239.339.4

7418022.5.39.640.539.939.339.239.539.139.239.039.1

7518226.6.38.738.739.139.139.639.739.539.539.539.439.1

7618423.3.38.939.339.439.239.239.139.639.439.138.838.8

7819028.6.39.339.439.239.639.639.239.239.439.539.2

8120221.7.38.738.839.039.339.239.339.439.239.439.2

8220330.7.38.838.738.739.038.839.239.138.738.738.639.1

8320428.6.38.838.938.939.039.039.138.738.838.838.9

842072.7.39.239.139.139.239.038.939.039.039.139.0

872162.7.38.638.538.839.139.539.439.739.539.639.2

8823718.3.38.938.638.938.839.039.039.139.439.339.539.3

892389.7.39.138.638.938.638.738.838.838.838.938.839.5

9124110.4.39.039.239.139.139.339.139.339.339.239.238.9

9424728.5.39.140.039.439.039.539.239.339.039.138.839.0

9625419.5.38.739.738.839.138.938.939.238.939.038.838.7

9725514.3.39.038.838.838.739.138.839.039.139.239.239.2

9825724.5.38.538.538.738.738.738.738.638.738.838.838.8

10025915.4.38.738.839.139.139.538.839.239.039.239.038.9

10126016.6.38.938.739.039.139.339.139.638.838.839.1

10226121.4.39.439.439.039.139.039.139.239.339.339.039.1

10526814.4.39.140.541.240.539.238.938.638.738.738.7

10627410.6.39.039.939.539.239.039.039.138.838.938.839.0

10727527.3.39.438.738.738.838.738.938.938.838.638.938.9

1082765.5.39.039.039.739.539.339.739.639.339.238.939.2

1102818.4.39.739.340.140.038.839.439.339.038.838.938.6

1122843.4.38.838.939.039.038.838.838.839.239.038.7

11529029.5.38.738.939.539.439.639.439.739.539.739.539.3

11629116.3.38.839.239.239.238.838.938.839.038.939.139.1

1172922.5.38.939.038.839.039.239.339.038.838.838.638.7

11929519.5.39.339.938.939.539.138.838.839.339.239.238.9

12029915.6.38.638.738.738.838.839.038.939.139.138.8

12330823.4.39.140.041.039.339.939.739.839.439.039.239.2

12430918.3.39.539.239.039.039.139.239.039.339.139.139.3

1253109.4.39.239.439.338.939.439.039.138.838.638.638.5

12831424.4.39.138.838.738.938.739.139.239.339.239.3

12931529.5.38.838.938.839.039.138.839.139.039.239.039.0

13232312.3.38.938.838.838.938.939.038.939.239.239.438.9

1333282.7.38.739.539.139.039.239.038.939.239.539.439.6

1353324.6.38.738.538.639.039.038.939.238.738.739.039.2

13733621.3.39.239.040.239.339.439.139.138.738.838.938.9

14635820.4.39.038.638.638.838.938.839.039.539.339.039.2

14936123.7.38.938.938.738.939.139.139.139.239.139.2

15137111.6.39.138.939.139.039.139.139.139.039.139.139.2

15237510.6.39.638.540.238.838.939.139.539.639.639.639.7

15538620.7.38.938.639.038.739.238.838.839.239.139.239.3

15639010.4.39.238.939.140.340.339.639.339.439.139.0

15739123.7.38.738.738.738.738.838.939.038.939.239.0

15839510.6.38.839.538.939.239.038.938.838.938.939.339.6

15939720.5.39.039.639.239.739.238.638.939.238.638.738.7

16140112.7.39.138.939.039.439.239.539.339.439.139.138.6

1644101.6.38.939.639.839.139.139.139.539.639.339.339.3

16541324.3.39.239.138.939.439.138.939.138.938.938.738.7

16842228.3.38.939.538.838.938.838.939.039.038.938.938.8

1734326.6.39.238.838.639.039.440.539.038.839.239.039.1

1754338.5.38.839.139.539.239.339.139.239.439.339.239.3

17743617.6.38.739.339.239.139.339.239.239.439.539.439.7

17843822.7.39.138.938.939.339.338.838.838.938.738.9

1794398.5.38.938.538.638.538.738.738.938.939.038.9

18044214.6.40.240.339.639.139.139.139.139.639.739.6

18144622.4.39.438.738.838.939.439.939.539.139.439.439.2

18345327.7.39.139.139.339.239.339.339.239.039.439.839.3

18445428.3.38.639.239.839.439.138.739.138.739.339.2

18645913.6.39.038.638.738.839.239.639.339.439.439.238.9

19047821.3.39.139.439.239.038.939.139.038.638.738.7

19449628.7.39.339.239.239.339.239.138.938.838.738.739.1

20151413.6.39.239.139.239.438.839.039.039.139.339.3

20352114.5.39.038.538.739.039.339.639.639.439.339.139.0

2045232.6.39.539.839.238.739.338.838.738.938.939.0

20552531.7.39.740.539.539.739.139.339.039.239.139.2

20752729.3.39.338.639.039.238.838.939.338.838.938.738.8

20852917.3.39.439.539.438.838.938.938.839.138.939.039.0

20954022.6.39.840.039.539.139.139.239.139.139.239.5

21154613.4.39.639.139.139.038.838.838.738.938.738.9

21354920.5.38.638.939.239.940.039.339.339.239.339.439.6

21555924.7.39.239.638.738.638.939.039.039.439.439.539.4

21656115.4.39.438.638.838.938.938.739.038.938.938.738.7

2175663.6.39.239.539.239.039.739.239.339.439.339.439.4

21856613.5.39.139.138.8

22057416.4.38.939.039.439.139.139.039.038.939.539.139.0

2215762.5.39.239.139.539.338.938.838.838.938.738.9

22257715.4.39.939.939.038.238.638.438.438.738.438.7

2245792.4.39.139.139.139.639.439.440.139.739.539.2

2255814.8.38.738.538.938.839.138.839.139.338.839.0

23260426.7.39.238.739.138.839.239.239.139.438.938.739.0

23460815.7.38.939.339.739.438.939.639.539.439.640.039.6

2356099.3.39.238.538.838.939.038.938.538.739.038.6

23661325.6.39.238.838.838.738.839.039.138.939.339.238.7

23762114.6.39.139.238.839.339.039.138.939.239.539.1

23962527.5.39.239.239.339.039.139.239.439.339.139.1

2406314.5.39.338.938.938.939.339.639.939.339.539.439.1

24364211.5.39.039.139.039.239.339.239.339.239.339.339.0

24464514.3.39.539.039.339.339.339.639.539.739.739.739.3

24564815.5.39.038.938.838.839.238.839.039.139.138.739.2

24765131.3.39.440.040.239.139.339.238.839.439.138.7

24865824.3.38.638.839.439.239.239.139.239.138.939.139.0

2496614.8.38.839.038.939.039.439.039.239.238.838.738.9

25266519.6.39.339.839.639.739.939.539.439.339.539.439.6

2546742.7.39.139.038.438.839.038.939.339.239.938.9

25567830.4.39.139.639.238.938.939.038.838.938.738.9

2566857.6.39.539.640.039.139.138.839.139.440.039.2

2586891.8.39.138.839.539.239.239.739.739.639.539.6

25969110.4.38.739.540.039.339.439.139.439.339.039.338.8

26170631.5.38.638.839.138.738.638.939.338.639.138.9

26270711.6.39.139.339.039.038.938.939.039.139.239.239.3

26470911.5.39.038.938.639.038.838.939.339.139.339.4

26972831.5.38.939.439.439.339.339.139.139.139.339.2

27274520.4.38.638.639.338.838.738.638.738.738.739.2

27474818.4.39.139.640.540.238.739.038.939.139.138.939.2

2777571.8.38.938.739.139.539.939.639.039.039.139.038.7

27875817.4.38.938.838.638.839.038.839.039.539.638.939.2

28277210.5.39.239.139.639.439.439.539.439.539.239.039.3

28377410.5.38.638.738.838.938.838.638.638.939.439.0

28678028.5.39.239.739.839.438.939.339.139.339.039.039.1

2907901.8.39.838.739.038.938.639.239.239.339.039.239.3

29179326.4.39.539.338.938.639.038.838.838.738.838.7

2947994.6.38.838.938.939.238.739.039.238.938.839.2

29780427.5.38.939.039.239.439.239.539.339.039.439.2

29980810.6.39.138.938.938.838.939.239.539.239.239.338.9

3008113.5.38.739.139.839.639.539.639.338.738.938.838.7

30281329.4.38.838.538.538.838.539.239.539.239.639.339.0

3038185.6.38.939.539.138.938.839.339.139.039.138.939.2

3108269.7.38.938.939.039.339.139.138.939.139.239.4

31284013.3.38.638.938.839.139.038.938.838.938.838.9

3148471.7.39.239.038.939.438.939.039.038.939.139.1

31585025.7.39.539.039.139.439.639.839.839.939.539.839.6

31886528.3.38.938.739.338.939.039.438.839.139.239.6

31986619.7.38.838.939.139.439.039.439.339.339.238.639.3

32187310.3.38.438.638.938.938.838.738.738.838.638.938.7

3228785.4.38.738.938.938.738.839.739.338.938.738.8

32388024.4.39.239.738.939.140.140.339.639.139.039.139.0

32889418.5.39.738.938.839.238.938.939.339.038.939.139.1

32989913.6.39.539.039.139.039.039.039.039.039.139.039.1

33090829.5.39.039.039.039.439.039.039.439.439.238.939.1

3319094.6.38.539.639.739.439.339.039.239.239.639.539.5

33491328.5.39.139.039.439.039.139.239.138.939.039.1

33591513.3.39.139.639.839.839.339.439.339.339.639.239.4

33992423.4.38.838.538.838.838.939.239.439.639.438.9

34193010.6.39.239.439.939.339.539.140.039.739.539.339.4

34393530.6.38.538.738.638.738.638.638.938.738.838.839.1

34593728.3.39.839.239.140.339.139.138.938.939.238.938.8

3469409.4.38.539.338.938.938.338.939.239.039.339.0

3489442.4.39.639.438.839.139.339.139.239.139.139.139.0

35396815.3.40.140.739.539.339.539.239.239.139.239.4

35497329.3.38.939.039.738.839.039.038.939.338.838.9

35598115.3.39.339.239.539.239.939.039.440.040.339.8

35798815.4.39.139.239.539.639.339.139.239.038.939.038.9

36199723.6.38.438.938.838.838.739.338.839.038.939.039.2

36299823.3.39.240.239.939.139.039.039.039.138.838.7

365100110.6.38.839.238.538.739.139.239.139.339.139.439.2

366101021.7.39.339.639.839.339.639.139.339.339.439.139.3

367101411.4.39.539.539.138.538.639.339.639.239.039.2

368101828.7.39.639.339.339.539.139.439.338.639.339.1

370102223.7.38.938.839.038.938.739.039.139.139.038.8

372102831.5.39.239.139.039.038.838.938.939.038.839.0

37310315.8.39.238.838.639.039.039.039.139.039.239.138.9

37610382.7.38.939.038.638.738.738.839.338.838.939.139.2

379104823.6.38.739.038.839.439.740.039.539.439.239.339.2

380104925.6.39.838.838.739.338.939.139.639.139.139.238.9

38210557.7.38.638.438.739.238.839.139.339.639.539.4

386106710.5.38.938.739.139.139.139.039.239.039.339.339.5

38710683.8.38.939.038.938.638.939.039.038.939.339.2

388107222.6.38.638.838.738.638.638.538.538.538.639.1

39010792.7.39.039.639.739.439.238.839.339.139.439.1

39210819.4.39.338.939.1

394109718.4.38.839.138.939.338.839.139.138.838.939.0

396109918.7.39.139.039.039.239.239.339.640.139.639.3

39911059.3.40.239.739.339.939.038.738.638.938.638.7

400110815.4.38.938.738.638.838.838.838.938.738.738.839.0

401112228.4.38.739.139.740.039.739.739.239.239.238.938.9

402112321.7.38.839.939.739.739.439.139.039.138.939.439.0

404113028.7.39.539.139.640.440.639.739.639.539.339.5

407113718.3.39.239.239.439.339.138.639.138.838.838.9

410114316.3.38.839.139.138.939.339.139.039.139.239.4

411114413.3.39.338.938.839.038.939.038.838.838.838.938.8

417119711.3.38.940.639.338.838.838.939.239.039.339.3

41811996.6.39.239.239.438.939.539.539.139.238.939.339.2

41912037.6.39.039.239.740.139.839.439.139.139.239.039.1

420120625.7.39.039.239.339.138.938.939.139.039.239.2

421121230.6.38.939.039.038.739.439.438.938.939.038.7

422121625.5.39.339.039.039.439.839.739.240.139.239.4

425122530.5.38.938.738.939.138.638.838.839.139.239.2

42612305.4.38.838.738.839.139.038.939.139.339.339.3

427123320.6.39.839.239.239.138.938.938.939.938.738.7

430123913.5.38.838.938.639.139.438.838.938.638.638.738.5

431124029.4.38.738.938.938.738.738.938.839.039.139.0

432124717.5.38.738.739.038.739.038.939.038.939.039.039.0

434125416.7.39.139.039.139.139.539.639.339.238.939.439.6

437126231.3.39.238.939.339.639.239.239.038.739.039.139.0

443128118.7.39.439.639.239.639.139.039.439.239.539.339.1

444128213.6.38.838.939.539.039.139.039.038.939.039.739.4

44512865.8.39.138.938.939.038.938.939.039.239.039.339.1

44612894.5.39.439.238.539.038.938.739.238.838.639.1

449131319.6.39.138.838.839.739.439.439.639.440.039.839.1

453132713.4.38.839.540.040.339.839.139.039.338.738.938.8

455133125.7.39.038.538.638.939.238.939.339.138.838.938.7

458135631.3.38.738.839.839.339.739.439.139.239.639.339.4

461136613.7.39.038.638.739.039.139.039.139.338.739.3

462137022.5.39.038.938.938.839.039.239.639.739.839.539.7

463137212.6.38.839.139.038.739.239.239.339.039.239.339.0

46413763.7.38.938.838.838.638.938.838.838.838.738.8

468139614.3.39.240.039.739.139.438.839.139.339.038.939.0

470140319.3.38.839.339.038.739.138.839.639.239.039.1

472140621.3.39.238.638.838.838.839.138.639.038.639.139.0

474140821.7.39.539.139.539.939.539.339.038.938.938.738.6

478141712.7.38.938.839.439.540.239.339.039.138.439.038.7

48014286.4.39.539.739.539.039.138.939.039.038.838.6

481143628.3.39.038.939.339.439.639.539.339.339.239.2

484144520.3.39.039.039.739.639.338.939.039.238.839.239.0

485144721.3.39.039.739.739.539.438.638.838.838.738.838.7

48714495.4.38.939.440.440.139.239.639.239.138.838.7

48914524.6.39.439.039.239.339.239.439.839.839.739.339.6

49114581.4.39.038.938.939.839.539.239.339.739.439.339.2

492145813.5.38.538.838.838.938.938.939.039.739.239.2

493145917.5.39.240.639.238.538.739.339.139.138.938.939.2

494146221.5.38.939.239.039.439.238.939.139.239.139.339.0

49514644.8.39.139.539.639.539.139.039.038.939.039.1

49614688.5.39.038.839.139.039.039.138.939.138.839.239.3

497146929.6.38.838.638.939.539.439.439.239.239.739.439.4

499147125.5.38.939.539.539.139.139.039.139.439.039.0

500147420.6.38.938.838.938.638.938.639.039.139.139.3

50214785.7.38.938.939.039.539.239.539.339.639.339.4

50414848.4.39.239.039.338.739.039.139.339.238.839.038.9

508149727.4.38.638.539.038.838.938.838.938.538.938.838.9

511150915.4.39.139.138.838.939.239.539.440.340.740.139.2

513151024.7.39.039.339.639.739.540.340.339.739.639.340.9

514152023.6.38.738.839.739.539.239.239.139.139.239.239.1

22658724.3.39.240.539.839.239.240.039.939.339.139.1

466139117.7.38.839.539.139.238.9

> 39,751832242112867102140komplett

012345678910550-10%1-10%2-10%

> 39,7271513157344928181.030.779.029.972.027.3

> 39,6366231710668125102von hinte addieren102.038.699.037.593.035.2

> 39,53914181113148151116132ermöglicht132.050.0129.048.9120.045.5

> 39,45911201611199171922158einschränkung ab 4. Tag158.059.8153.058.0144.054.5

> 39,36109181991721142741191(Metritis)191.072.3185.070.1175.066.3

0+11+22+33+44+55+66+77+88+99+10

> 39,706884140213412.9

> 39,6

> 39,5

> 39,4

> 39,3

Tag der

Messung

post partum

gesund gesamt

Stallnr.Tag partus012345678910

2514.3.39.139.839.939.439.839.739.439.439.238.939.0

4920.4.39.839.640.140.139.939.539.239.539.539.239.4

51026.6.39.140.140.340.239.739.739.339.539.138.939.1

81614.4.39.739.439.840.239.439.339.039.439.139.239.1

9181.4.39.038.638.638.838.738.938.638.838.838.438.9

101920.5.38.838.838.639.138.838.838.639.038.538.8

12202.7.38.838.939.038.838.838.739.038.739.038.7

142211.5.38.838.738.738.839.139.339.139.139.439.239.2

184310.3.39.138.738.738.838.738.738.938.840.238.6

194613.3.38.939.039.039.539.239.238.939.239.238.9

21503.4.39.138.939.038.938.538.738.738.638.838.938.9

235824.6.38.838.638.839.039.039.039.038.938.738.7

276412.7.38.738.839.539.940.240.139.739.539.439.539.3

286826.7.39.138.638.938.938.939.039.438.839.339.039.4

296925.6.39.339.339.539.238.939.339.239.339.138.939.0

307129.7.39.139.739.739.439.539.039.639.139.139.339.2

338129.5.39.039.338.939.039.039.439.239.239.139.1

348413.4.38.738.940.239.640.339.639.239.239.339.239.0

358819.6.39.338.738.738.938.939.038.938.839.039.038.9

36956.6.39.338.738.938.939.339.739.138.838.838.9

3710022.6.38.838.739.139.339.038.938.838.839.138.9

381035.6.39.339.139.239.338.939.039.239.239.038.739.0

431202.8.39.338.838.739.038.939.138.839.439.238.939.0

4412118.4.39.239.038.739.139.039.039.339.038.838.838.7

4612516.4.39.639.839.039.139.139.339.239.239.239.139.4

4712716.6.40.039.139.640.240.039.439.639.339.239.138.8

4812818.4.39.540.539.839.839.439.439.139.139.039.1

4912925.6.39.038.738.739.039.239.039.239.239.239.339.2

5414918.7.38.938.938.938.639.139.439.539.439.238.738.8

5515211.6.38.838.739.039.338.839.039.139.139.038.639.1

611658.6.38.738.939.238.738.638.638.838.938.838.6

6216714.6.38.938.638.538.639.039.039.239.039.538.939.2

631682.4.39.138.639.439.439.139.239.439.439.339.439.3

6416917.6.38.839.939.139.039.539.438.939.339.539.939.4

701755.4.39.039.139.039.640.139.839.939.839.639.339.5

7117625.5.38.839.039.039.439.839.339.439.038.938.738.9

7317720.7.38.838.738.939.039.239.539.039.039.239.339.4

7418022.5.39.640.539.939.339.239.539.139.239.039.1

7518226.6.38.738.739.139.139.639.739.539.539.539.439.1

7618423.3.38.939.339.439.239.239.139.639.439.138.838.8

7819028.6.39.339.439.239.639.639.239.239.439.539.2

8120221.7.38.738.839.039.339.239.339.439.239.439.2

8220330.7.38.838.738.739.038.839.239.138.738.738.639.1

8320428.6.38.838.938.939.039.039.138.738.838.838.9

842072.7.39.239.139.139.239.038.939.039.039.139.0

872162.7.38.638.538.839.139.539.439.739.539.639.2

8823718.3.38.938.638.938.839.039.039.139.439.339.539.3

892389.7.39.138.638.938.638.738.838.838.838.938.839.5

9124110.4.39.039.239.139.139.339.139.339.339.239.238.9

9424728.5.39.140.039.439.039.539.239.339.039.138.839.0

9625419.5.38.739.738.839.138.938.939.238.939.038.838.7

9725514.3.39.038.838.838.739.138.839.039.139.239.239.2

9825724.5.38.538.538.738.738.738.738.638.738.838.838.8

10025915.4.38.738.839.139.139.538.839.239.039.239.038.9

10126016.6.38.938.739.039.139.339.139.638.838.839.1

10226121.4.39.439.439.039.139.039.139.239.339.339.039.1

10526814.4.39.140.541.240.539.238.938.638.738.738.7

10627410.6.39.039.939.539.239.039.039.138.838.938.839.0

10727527.3.39.438.738.738.838.738.938.938.838.638.938.9

1082765.5.39.039.039.739.539.339.739.639.339.238.939.2

1102818.4.39.739.340.140.038.839.439.339.038.838.938.6

1122843.4.38.838.939.039.038.838.838.839.239.038.7

11529029.5.38.738.939.539.439.639.439.739.539.739.539.3

11629116.3.38.839.239.239.238.838.938.839.038.939.139.1

1172922.5.38.939.038.839.039.239.339.038.838.838.638.7

11929519.5.39.339.938.939.539.138.838.839.339.239.238.9

12029915.6.38.638.738.738.838.839.038.939.139.138.8

12330823.4.39.140.041.039.339.939.739.839.439.039.239.2

12430918.3.39.539.239.039.039.139.239.039.339.139.139.3

1253109.4.39.239.439.338.939.439.039.138.838.638.638.5

12831424.4.39.138.838.738.938.739.139.239.339.239.3

12931529.5.38.838.938.839.039.138.839.139.039.239.039.0

13232312.3.38.938.838.838.938.939.038.939.239.239.438.9

1333282.7.38.739.539.139.039.239.038.939.239.539.439.6

1353324.6.38.738.538.639.039.038.939.238.738.739.039.2

13733621.3.39.239.040.239.339.439.139.138.738.838.938.9

14635820.4.39.038.638.638.838.938.839.039.539.339.039.2

14936123.7.38.938.938.738.939.139.139.139.239.139.2

15137111.6.39.138.939.139.039.139.139.139.039.139.139.2

15237510.6.39.638.540.238.838.939.139.539.639.639.639.7

15538620.7.38.938.639.038.739.238.838.839.239.139.239.3

15639010.4.39.238.939.140.340.339.639.339.439.139.0

15739123.7.38.738.738.738.738.838.939.038.939.239.0

15839510.6.38.839.538.939.239.038.938.838.938.939.339.6

15939720.5.39.039.639.239.739.238.638.939.238.638.738.7

16140112.7.39.138.939.039.439.239.539.339.439.139.138.6

1644101.6.38.939.639.839.139.139.139.539.639.339.339.3

16541324.3.39.239.138.939.439.138.939.138.938.938.738.7

16842228.3.38.939.538.838.938.838.939.039.038.938.938.8

1734326.6.39.238.838.639.039.440.539.038.839.239.039.1

1754338.5.38.839.139.539.239.339.139.239.439.339.239.3

17743617.6.38.739.339.239.139.339.239.239.439.539.439.7

17843822.7.39.138.938.939.339.338.838.838.938.738.9

1794398.5.38.938.538.638.538.738.738.938.939.038.9

18044214.6.40.240.339.639.139.139.139.139.639.739.6

18144622.4.39.438.738.838.939.439.939.539.139.439.439.2

18345327.7.39.139.139.339.239.339.339.239.039.439.839.3

18445428.3.38.639.239.839.439.138.739.138.739.339.2

18645913.6.39.038.638.738.839.239.639.339.439.439.238.9

19047821.3.39.139.439.239.038.939.139.038.638.738.7

19449628.7.39.339.239.239.339.239.138.938.838.738.739.1

20151413.6.39.239.139.239.438.839.039.039.139.339.3

20352114.5.39.038.538.739.039.339.639.639.439.339.139.0

2045232.6.39.539.839.238.739.338.838.738.938.939.0

20552531.7.39.740.539.539.739.139.339.039.239.139.2

20752729.3.39.338.639.039.238.838.939.338.838.938.738.8

20852917.3.39.439.539.438.838.938.938.839.138.939.039.0

20954022.6.39.840.039.539.139.139.239.139.139.239.5

21154613.4.39.639.139.139.038.838.838.738.938.738.9

21354920.5.38.638.939.239.940.039.339.339.239.339.439.6

21555924.7.39.239.638.738.638.939.039.039.439.439.539.4

21656115.4.39.438.638.838.938.938.739.038.938.938.738.7

2175663.6.39.239.539.239.039.739.239.339.439.339.439.4

21856613.5.39.139.138.8

22057416.4.38.939.039.439.139.139.039.038.939.539.139.0

2215762.5.39.239.139.539.338.938.838.838.938.738.9

22257715.4.39.939.939.038.238.638.438.438.738.438.7

2245792.4.39.139.139.139.639.439.440.139.739.539.2

2255814.8.38.738.538.938.839.138.839.139.338.839.0

23260426.7.39.238.739.138.839.239.239.139.438.938.739.0

23460815.7.38.939.339.739.438.939.639.539.439.640.039.6

2356099.3.39.238.538.838.939.038.938.538.739.038.6

23661325.6.39.238.838.838.738.839.039.138.939.339.238.7

23762114.6.39.139.238.839.339.039.138.939.239.539.1

23962527.5.39.239.239.339.039.139.239.439.339.139.1

2406314.5.39.338.938.938.939.339.639.939.339.539.439.1

24364211.5.39.039.139.039.239.339.239.339.239.339.339.0

24464514.3.39.539.039.339.339.339.639.539.739.739.739.3

24564815.5.39.038.938.838.839.238.839.039.139.138.739.2

24765131.3.39.440.040.239.139.339.238.839.439.138.7

24865824.3.38.638.839.439.239.239.139.239.138.939.139.0

2496614.8.38.839.038.939.039.439.039.239.238.838.738.9

25266519.6.39.339.839.639.739.939.539.439.339.539.439.6

2546742.7.39.139.038.438.839.038.939.339.239.938.9

25567830.4.39.139.639.238.938.939.038.838.938.738.9

2566857.6.39.539.640.039.139.138.839.139.440.039.2

2586891.8.39.138.839.539.239.239.739.739.639.539.6

25969110.4.38.739.540.039.339.439.139.439.339.039.338.8

26170631.5.38.638.839.138.738.638.939.338.639.138.9

26270711.6.39.139.339.039.038.938.939.039.139.239.239.3

26470911.5.39.038.938.639.038.838.939.339.139.339.4

26972831.5.38.939.439.439.339.339.139.139.139.339.2

27274520.4.38.638.639.338.838.738.638.738.738.739.2

27474818.4.39.139.640.540.238.739.038.939.139.138.939.2

2777571.8.38.938.739.139.539.939.639.039.039.139.038.7

27875817.4.38.938.838.638.839.038.839.039.539.638.939.2

28277210.5.39.239.139.639.439.439.539.439.539.239.039.3

28377410.5.38.638.738.838.938.838.638.638.939.439.0

28678028.5.39.239.739.839.438.939.339.139.339.039.039.1

2907901.8.39.838.739.038.938.639.239.239.339.039.239.3

29179326.4.39.539.338.938.639.038.838.838.738.838.7

2947994.6.38.838.938.939.238.739.039.238.938.839.2

29780427.5.38.939.039.239.439.239.539.339.039.439.2

29980810.6.39.138.938.938.838.939.239.539.239.239.338.9

3008113.5.38.739.139.839.639.539.639.338.738.938.838.7

30281329.4.38.838.538.538.838.539.239.539.239.639.339.0

3038185.6.38.939.539.138.938.839.339.139.039.138.939.2

3108269.7.38.938.939.039.339.139.138.939.139.239.4

31284013.3.38.638.938.839.139.038.938.838.938.838.9

3148471.7.39.239.038.939.438.939.039.038.939.139.1

31585025.7.39.539.039.139.439.639.839.839.939.539.839.6

31886528.3.38.938.739.338.939.039.438.839.139.239.6

31986619.7.38.838.939.139.439.039.439.339.339.238.639.3

32187310.3.38.438.638.938.938.838.738.738.838.638.938.7

3228785.4.38.738.938.938.738.839.739.338.938.738.8

32388024.4.39.239.738.939.140.140.339.639.139.039.139.0

32889418.5.39.738.938.839.238.938.939.339.038.939.139.1

32989913.6.39.539.039.139.039.039.039.039.039.139.039.1

33090829.5.39.039.039.039.439.039.039.439.439.238.939.1

3319094.6.38.539.639.739.439.339.039.239.239.639.539.5

33491328.5.39.139.039.439.039.139.239.138.939.039.1

33591513.3.39.139.639.839.839.339.439.339.339.639.239.4

33992423.4.38.838.538.838.838.939.239.439.639.438.9

34193010.6.39.239.439.939.339.539.140.039.739.539.339.4

34393530.6.38.538.738.638.738.638.638.938.738.838.839.1

34593728.3.39.839.239.140.339.139.138.938.939.238.938.8

3469409.4.38.539.338.938.938.338.939.239.039.339.0

3489442.4.39.639.438.839.139.339.139.239.139.139.139.0

35396815.3.40.140.739.539.339.539.239.239.139.239.4

35497329.3.38.939.039.738.839.039.038.939.338.838.9

35598115.3.39.339.239.539.239.939.039.440.040.339.8

35798815.4.39.139.239.539.639.339.139.239.038.939.038.9

36199723.6.38.438.938.838.838.739.338.839.038.939.039.2

36299823.3.39.240.239.939.139.039.039.039.138.838.7

365100110.6.38.839.238.538.739.139.239.139.339.139.439.2

366101021.7.39.339.639.839.339.639.139.339.339.439.139.3

367101411.4.39.539.539.138.538.639.339.639.239.039.2

368101828.7.39.639.339.339.539.139.439.338.639.339.1

370102223.7.38.938.839.038.938.739.039.139.139.038.8

372102831.5.39.239.139.039.038.838.938.939.038.839.0

37310315.8.39.238.838.639.039.039.039.139.039.239.138.9

37610382.7.38.939.038.638.738.738.839.338.838.939.139.2

379104823.6.38.739.038.839.439.740.039.539.439.239.339.2

380104925.6.39.838.838.739.338.939.139.639.139.139.238.9

38210557.7.38.638.438.739.238.839.139.339.639.539.4

386106710.5.38.938.739.139.139.139.039.239.039.339.339.5

38710683.8.38.939.038.938.638.939.039.038.939.339.2

388107222.6.38.638.838.738.638.638.538.538.538.639.1

39010792.7.39.039.639.739.439.238.839.339.139.439.1

39210819.4.39.338.939.1

394109718.4.38.839.138.939.338.839.139.138.838.939.0

396109918.7.39.139.039.039.239.239.339.640.139.639.3

39911059.3.40.239.739.339.939.038.738.638.938.638.7

400110815.4.38.938.738.638.838.838.838.938.738.738.839.0

401112228.4.38.739.139.740.039.739.739.239.239.238.938.9

402112321.7.38.839.939.739.739.439.139.039.138.939.439.0

404113028.7.39.539.139.640.440.639.739.639.539.339.5

407113718.3.39.239.239.439.339.138.639.138.838.838.9

410114316.3.38.839.139.138.939.339.139.039.139.239.4

411114413.3.39.338.938.839.038.939.038.838.838.838.938.8

417119711.3.38.940.639.338.838.838.939.239.039.339.3

41811996.6.39.239.239.438.939.539.539.139.238.939.339.2

41912037.6.39.039.239.740.139.839.439.139.139.239.039.1

420120625.7.39.039.239.339.138.938.939.139.039.239.2

421121230.6.38.939.039.038.739.439.438.938.939.038.7

422121625.5.39.339.039.039.439.839.739.240.139.239.4

425122530.5.38.938.738.939.138.638.838.839.139.239.2

42612305.4.38.838.738.839.139.038.939.139.339.339.3

427123320.6.39.839.239.239.138.938.938.939.938.738.7

430123913.5.38.838.938.639.139.438.838.938.638.638.738.5

431124029.4.38.738.938.938.738.738.938.839.039.139.0

432124717.5.38.738.739.038.739.038.939.038.939.039.039.0

434125416.7.39.139.039.139.139.539.639.339.238.939.439.6

437126231.3.39.238.939.339.639.239.239.038.739.039.139.0

443128118.7.39.439.639.239.639.139.039.439.239.539.339.1

444128213.6.38.838.939.539.039.139.039.038.939.039.739.4

44512865.8.39.138.938.939.038.938.939.039.239.039.339.1

44612894.5.39.439.238.539.038.938.739.238.838.639.1

449131319.6.39.138.838.839.739.439.439.639.440.039.839.1

453132713.4.38.839.540.040.339.839.139.039.338.738.938.8

455133125.7.39.038.538.638.939.238.939.339.138.838.938.7

458135631.3.38.738.839.839.339.739.439.139.239.639.339.4

461136613.7.39.038.638.739.039.139.039.139.338.739.3

462137022.5.39.038.938.938.839.039.239.639.739.839.539.7

463137212.6.38.839.139.038.739.239.239.339.039.239.339.0

46413763.7.38.938.838.838.638.938.838.838.838.738.8

468139614.3.39.240.039.739.139.438.839.139.339.038.939.0

470140319.3.38.839.339.038.739.138.839.639.239.039.1

472140621.3.39.238.638.838.838.839.138.639.038.639.139.0

474140821.7.39.539.139.539.939.539.339.038.938.938.738.6

478141712.7.38.938.839.439.540.239.339.039.138.439.038.7

48014286.4.39.539.739.539.039.138.939.039.038.838.6

481143628.3.39.038.939.339.439.639.539.339.339.239.2

484144520.3.39.039.039.739.639.338.939.039.238.839.239.0

485144721.3.39.039.739.739.539.438.638.838.838.738.838.7

48714495.4.38.939.440.440.139.239.639.239.138.838.7

48914524.6.39.439.039.239.339.239.439.839.839.739.339.6

49114581.4.39.038.938.939.839.539.239.339.739.439.339.2

492145813.5.38.538.838.838.938.938.939.039.739.239.2

493145917.5.39.240.639.238.538.739.339.139.138.938.939.2

494146221.5.38.939.239.039.439.238.939.139.239.139.339.0

49514644.8.39.139.539.639.539.139.039.038.939.039.1

49614688.5.39.038.839.139.039.039.138.939.138.839.239.3

497146929.6.38.838.638.939.539.439.439.239.239.739.439.4

499147125.5.38.939.539.539.139.139.039.139.439.039.0

500147420.6.38.938.838.938.638.938.639.039.139.139.3

50214785.7.38.938.939.039.539.239.539.339.639.339.4

50414848.4.39.239.039.338.739.039.139.339.238.839.038.9

508149727.4.38.638.539.038.838.938.838.938.538.938.838.9

511150915.4.39.139.138.838.939.239.539.440.340.740.139.2

513151024.7.39.039.339.639.739.540.340.339.739.639.340.9

514152023.6.38.738.839.739.539.239.239.139.139.239.239.1

22658724.3.39.240.539.839.239.240.039.939.339.139.1

466139117.7.38.839.539.139.238.9

MW39.039.139.139.239.139.139.139.139.139.139.1

Min38.438.538.438.438.238.338.438.438.438.438.5

Max40.040.641.041.240.540.640.340.340.740.340.9

Stabw.0.30.40.50.40.40.30.30.30.30.30.3

MW39.1

0.0

Tag derMW± sMinMax

Tag derMW± sMinMaxMessungin °Cin °Cin °Cin °C

Messungin °Cin °Cin °Cin °Cpost partum

post partum1. Tag39.10.538.140.8

1. Tag39.10.538.140.82. Tag39.10.538.241.4

2. Tag39.10.538.241.43. Tag39.20.538.341.6

3. Tag39.20.538.341.64. Tag39.10.53841.5

4. Tag39.10.53841.55. Tag39.10.438.141.3

5. Tag39.10.438.141.36. Tag39.10.43840.6

6. Tag39.10.43840.67. Tag39.10.438.240.9

7. Tag39.10.438.240.98. Tag39.10.438.241

8. Tag39.10.438.2419. Tag39.10.438.141.2

9. Tag39.10.438.141.210. Tag39.10.338.441

10. Tag39.10.338.441

39.047546012339.052083333339.144507575839.1539.138167938939.105363984739.112643678239.100957854439.099233716539.075670498139.062835249

38.438.4538.438.438.238.338.3538.438.438.3538.45

4040.640.9541.1540.540.640.340.2540.6540.2540.85

0.29983553520.3900441340.48402045640.40714405750.37866128680.34170100750.30228791590.29386195440.31901197680.31245312060.2839251114

Tag derMW± sMinMax

Messungin °Cin °Cin °Cin °C

post partum

1. Tag39.10.39004413438.4540.6

2. Tag39.10.484020456438.440.95

3. Tag39.20.407144057538.441.15

4. Tag39.10.378661286838.240.5

5. Tag39.10.341701007538.340.6

6. Tag39.10.302287915938.3540.3

7. Tag39.10.293861954438.440.25

8. Tag39.10.319011976838.440.65

9. Tag39.10.312453120638.3540.25

10. Tag39.10.283925111438.4540.85

24

45

31

27

18

15

13

13

13

5

Tabelle4

2514.3.39.139.7539.8539.3539.7539.6539.3539.439.1538.8539

4920.4.39.839.640.0540.0539.939.4539.1539.4539.4539.239.35

51026.6.39.140.0540.2540.239.6539.6539.2539.4539.0538.939.05

81614.4.39.739.439.7540.1539.439.253939.3539.0539.1539.05

81614.4.39.739.439.7540.1539.439.253939.3539.0539.1539.05

184310.3.39.0538.738.738.7538.6538.738.8538.840.238.6

276412.7.38.738.7539.4539.8540.240.139.6539.4539.3539.539.3

348413.4.38.738.940.1539.640.339.5539.239.239.2539.238.95

4612516.4.39.639.7538.9539.139.139.2539.1539.1539.239.139.35

4712716.6.4039.0539.640.239.9539.439.5539.339.239.138.8

4812818.4.39.4540.539.7539.839.439.439.139.13939.05

6416917.6.38.839.939.13939.4539.438.939.2539.539.8539.35

701755.4.3939.053939.5540.0539.839.939.839.639.2539.5

7117625.5.38.838.953939.439.839.339.3538.9538.938.738.9

7418022.5.39.5540.4539.8539.2539.239.539.139.1538.9539.05

9424728.5.39.14039.438.9539.4539.239.2538.9539.0538.839

10526814.4.39.140.4541.1540.539.1538.938.638.6538.738.7

10627410.6.3939.8539.4539.1538.953939.0538.838.8538.7539

1102818.4.39.739.2540.139.9538.7539.3539.33938.838.938.55

11929519.5.39.339.8538.8539.539.138.7538.839.2539.239.1538.85

12330823.4.39.14040.9539.339.8539.6539.839.43939.1539.2

13733621.3.39.23940.239.339.439.0539.0538.738.7538.938.9

15237510.6.39.638.540.1538.838.8539.139.4539.639.639.5539.65

15639010.4.39.238.939.0540.340.339.5539.2539.439.139

1644101.6.38.939.5539.839.139.0539.0539.4539.639.2539.2539.25

1734326.6.39.238.838.638.9539.440.4538.9538.7539.238.9539.05

18044214.6.40.1540.2539.639.0539.0539.139.0539.639.6539.6

18144622.4.39.3538.738.7538.939.3539.8539.4539.0539.3539.3539.15

18345327.7.39.0539.139.339.1539.2539.339.238.9539.439.7539.3

18445428.3.38.5539.239.839.3539.0538.739.0538.6539.2539.2

2045232.6.39.4539.839.1538.739.338.838.6538.938.939

20552531.7.39.740.4539.539.739.139.33939.239.0539.15

20954022.6.39.839.9539.539.0539.0539.239.0539.0539.239.45

21354920.5.38.638.8539.239.8539.9539.2539.2539.1539.339.439.55

22257715.4.39.8539.93938.238.5538.3538.438.6538.3538.7

2245792.4.39.0539.139.0539.5539.439.3540.0539.6539.4539.2

22658724.3.39.240.539.839.239.239.9539.939.339.0539.05

23460815.7.38.939.2539.739.438.8539.5539.4539.439.639.9539.6

2406314.5.39.338.8538.8538.939.2539.5539.8539.2539.539.439.1

24765131.3.39.439.9540.1539.139.339.238.839.3539.0538.65

25266519.6.39.339.839.639.6539.8539.4539.3539.339.4539.439.6

2546742.7.39.138.9538.438.753938.8539.2539.1539.8538.9

2566857.6.39.539.639.9539.139.138.839.139.439.9539.2

25969110.4.38.739.54039.339.3539.0539.3539.2538.9539.338.8

27474818.4.39.139.640.540.238.73938.939.0539.138.8539.2

2777571.8.38.938.6539.139.539.8539.55393939.0538.9538.7

28678028.5.39.239.6539.7539.438.8539.339.139.3393939.1

2907901.8.39.838.6538.9538.8538.5539.239.1539.338.9539.239.25

3008113.5.38.739.139.839.639.539.5539.338.6538.8538.838.7

31585025.7.39.538.9539.0539.439.639.839.7539.8539.4539.7539.55

32388024.4.39.239.6538.939.0540.140.339.639.138.9539.139

33591513.3.39.139.639.7539.839.2539.3539.339.339.5539.239.4

34193010.6.39.239.439.8539.2539.4539.054039.6539.4539.339.35

34593728.3.39.839.1539.140.2539.0539.0538.938.939.238.8538.8

35396815.3.40.0540.6539.4539.2539.539.1539.239.139.239.4

35598115.3.39.2539.239.4539.1539.93939.44040.2539.8

36299823.3.39.240.239.8539.05393938.9539.138.838.7

366101021.7.39.2539.639.7539.2539.639.0539.339.2539.3539.139.25

379104823.6.38.738.9538.839.439.74039.539.439.1539.2539.2

380104925.6.39.838.7538.739.338.8539.0539.639.139.0539.238.9

396109918.7.39.138.9538.9539.239.1539.339.640.0539.639.3

39911059.3.40.239.739.2539.8538.9538.738.638.938.638.65

401112228.4.38.739.139.654039.6539.6539.239.239.1538.938.85

402112321.7.38.839.939.6539.739.3539.053939.138.939.3539

404113028.7.39.4539.139.640.440.639.6539.639.539.339.45

417119711.3.38.940.5539.338.7538.838.8539.23939.339.25

41912037.6.3939.239.6540.0539.7539.3539.0539.139.153939.05

422121625.5.39.2538.953939.3539.7539.739.240.0539.1539.35

427123320.6.39.7539.1539.1539.0538.8538.938.8539.938.6538.7

449131319.6.39.138.7538.7539.6539.3539.439.639.439.9539.839.05

453132713.4.38.839.454040.339.7539.138.9539.2538.738.8538.75

458135631.3.38.738.7539.839.2539.739.439.0539.239.5539.339.35

462137022.5.3938.938.8538.83939.239.639.6539.839.539.65

468139614.3.39.239.9539.6539.0539.438.839.139.2538.9538.939

474140821.7.39.539.0539.539.8539.4539.33938.8538.8538.738.6

478141712.7.38.938.7539.439.4540.1539.253939.0538.438.9538.7

48714495.4.38.8539.3540.3540.139.239.639.1539.0538.7538.7

48914524.6.39.438.9539.1539.2539.239.3539.7539.839.739.2539.55

49114581.4.3938.938.939.839.4539.239.2539.739.439.339.15

493145917.5.39.1540.639.238.538.739.339.139.0538.938.939.15

511150915.4.39.0539.0538.838.8539.1539.4539.440.2540.6540.0539.15

513151024.7.3939.339.639.6539.4540.2540.339.739.639.2540.85

zum löschen

Stallnr.Tag partus012345678910

9181.4.39.038.638.638.838.738.938.638.838.838.438.9

101920.5.38.838.838.639.138.838.838.639.038.538.8

12202.7.38.838.939.038.838.838.739.038.739.038.7

38.838.738.738.839.139.339.139.139.439.239.2

39.138.738.738.838.738.738.938.840.238.6

38.939.039.039.539.239.238.939.239.238.9

21503.4.39.138.939.038.938.538.738.738.638.838.938.9

235824.6.38.838.638.839.039.039.039.038.938.738.7

39.138.638.938.938.939.039.438.839.339.039.4

39.339.339.539.238.939.339.239.339.138.939.0

39.139.739.739.439.539.039.639.139.139.339.2

39.039.338.939.039.039.439.239.239.139.1

38.738.940.239.640.339.639.239.239.339.239.0

358819.6.39.338.738.738.938.939.038.938.839.039.038.9

39.338.738.938.939.339.739.138.838.838.9

3710022.6.38.838.739.139.339.038.938.838.839.138.9

381035.6.39.339.139.239.338.939.039.239.239.038.739.0

39.338.838.739.038.939.138.839.439.238.939.0

4412118.4.39.239.038.739.139.039.039.339.038.838.838.7

39.639.839.039.139.139.339.239.239.239.139.4

4912925.6.39.038.738.739.039.239.039.239.239.239.339.2

38.938.938.938.639.139.439.539.439.238.738.8

5515211.6.38.838.739.039.338.839.039.139.139.038.639.1

611658.6.38.738.939.238.738.638.638.838.938.838.6

38.938.638.538.639.039.039.239.039.538.939.2

39.138.639.439.439.139.239.439.439.339.439.3

38.839.939.139.039.539.438.939.339.539.939.4

38.839.039.039.439.839.339.439.038.938.738.9

38.838.738.939.039.239.539.039.039.239.339.4

38.738.739.139.139.639.739.539.539.539.439.1

38.939.339.439.239.239.139.639.439.138.838.8

39.339.439.239.639.639.239.239.439.539.2

38.738.839.039.339.239.339.439.239.439.2

8220330.7.38.838.738.739.038.839.239.138.738.738.639.1

8320428.6.38.838.938.939.039.039.138.738.838.838.9

842072.7.39.239.139.139.239.038.939.039.039.139.0

38.638.538.839.139.539.439.739.539.639.2

38.938.638.938.839.039.039.139.439.339.539.3

39.138.638.938.638.738.838.838.838.938.839.5

9124110.4.39.039.239.139.139.339.139.339.339.239.238.9

39.140.039.439.039.539.239.339.039.138.839.0

38.739.738.839.138.938.939.238.939.038.838.7

9725514.3.39.038.838.838.739.138.839.039.139.239.239.2

9825724.5.38.538.538.738.738.738.738.638.738.838.838.8

38.738.839.139.139.538.839.239.039.239.038.9

38.938.739.039.139.339.139.638.838.839.1

39.439.439.039.139.039.139.239.339.339.039.1

39.039.939.539.239.039.039.138.838.938.839.0

39.438.738.738.838.738.938.938.838.638.938.9

39.039.039.739.539.339.739.639.339.238.939.2

1122843.4.38.838.939.039.038.838.838.839.239.038.7

38.738.939.539.439.639.439.739.539.739.539.3

11629116.3.38.839.239.239.238.838.938.839.038.939.139.1

1172922.5.38.939.038.839.039.239.339.038.838.838.638.7

39.339.938.939.539.138.838.839.339.239.238.9

12029915.6.38.638.738.738.838.839.038.939.139.138.8

39.539.239.039.039.139.239.039.339.139.139.3

39.239.439.338.939.439.039.138.838.638.638.5

12831424.4.39.138.838.738.938.739.139.239.339.239.3

12931529.5.38.838.938.839.039.138.839.139.039.239.039.0

38.938.838.838.938.939.038.939.239.239.438.9

38.739.539.139.039.239.038.939.239.539.439.6

1353324.6.38.738.538.639.039.038.939.238.738.739.039.2

39.239.040.239.339.439.139.138.738.838.938.9

39.038.638.638.838.938.839.039.539.339.039.2

14936123.7.38.938.938.738.939.139.139.139.239.139.2

15137111.6.39.138.939.139.039.139.139.139.039.139.139.2

39.638.540.238.838.939.139.539.639.639.639.7

15538620.7.38.938.639.038.739.238.838.839.239.139.239.3

15739123.7.38.738.738.738.738.838.939.038.939.239.0

38.839.538.939.239.038.938.838.938.939.339.6

39.039.639.239.739.238.638.939.238.638.738.7

39.138.939.039.439.239.539.339.439.139.138.6

38.939.639.839.139.139.139.539.639.339.339.3

39.239.138.939.439.138.939.138.938.938.738.7

38.939.538.838.938.838.939.039.038.938.938.8

39.238.838.639.039.440.539.038.839.239.039.1

38.839.139.539.239.339.139.239.439.339.239.3

38.739.339.239.139.339.239.239.439.539.439.7

17843822.7.39.138.938.939.339.338.838.838.938.738.9

1794398.5.38.938.538.638.538.738.738.938.939.038.9

39.438.738.838.939.439.939.539.139.439.439.2

39.139.139.339.239.339.339.239.039.439.839.3

38.639.239.839.439.138.739.138.739.339.2

39.038.638.738.839.239.639.339.439.439.238.9

39.139.439.239.038.939.139.038.638.738.7

19449628.7.39.339.239.239.339.239.138.938.838.738.739.1

39.239.139.239.438.839.039.039.139.339.3

39.038.538.739.039.339.639.639.439.339.139.0

39.539.839.238.739.338.838.738.938.939.0

39.740.539.539.739.139.339.039.239.139.2

20752729.3.39.338.639.039.238.838.939.338.838.938.738.8

39.439.539.438.838.938.938.839.138.939.039.0

39.639.139.139.038.838.838.738.938.738.9

39.239.638.738.638.939.039.039.439.439.539.4

39.438.638.838.938.938.739.038.938.938.738.7

39.239.539.239.039.739.239.339.439.339.439.4

21856613.5.39.139.138.8

38.939.039.439.139.139.039.038.939.539.139.0

39.239.139.539.338.938.838.838.938.738.9

39.139.139.139.639.439.440.139.739.539.2

2255814.8.38.738.538.938.839.138.839.139.338.839.0

39.238.739.138.839.239.239.139.438.938.739.0

38.939.339.739.438.939.639.539.439.640.039.6

2356099.3.39.238.538.838.939.038.938.538.739.038.6

23661325.6.39.238.838.838.738.839.039.138.939.339.238.7

39.139.238.839.339.039.138.939.239.539.1

39.239.239.339.039.139.239.439.339.139.1

39.338.938.938.939.339.639.939.339.539.439.1

24364211.5.39.039.139.039.239.339.239.339.239.339.339.0

39.539.039.339.339.339.639.539.739.739.739.3

24564815.5.39.038.938.838.839.238.839.039.139.138.739.2

38.638.839.439.239.239.139.239.138.939.139.0

38.839.038.939.039.439.039.239.238.838.738.9

39.339.839.639.739.939.539.439.339.539.439.6

39.139.038.438.839.038.939.339.239.938.9

39.139.639.238.938.939.038.838.938.738.9

39.539.640.039.139.138.839.139.440.039.2

39.138.839.539.239.239.739.739.639.539.6

38.739.540.039.339.439.139.439.339.039.338.8

26170631.5.38.638.839.138.738.638.939.338.639.138.9

26270711.6.39.139.339.039.038.938.939.039.139.239.239.3

39.038.938.639.038.838.939.339.139.339.4

38.939.439.439.339.339.139.139.139.339.2

27274520.4.38.638.639.338.838.738.638.738.738.739.2

38.938.739.139.539.939.639.039.039.139.038.7

38.938.838.638.839.038.839.039.539.638.939.2

39.239.139.639.439.439.539.439.539.239.039.3

38.638.738.838.938.838.638.638.939.439.0

39.239.739.839.438.939.339.139.339.039.039.1

39.838.739.038.938.639.239.239.339.039.239.3

39.539.338.938.639.038.838.838.738.838.7

2947994.6.38.838.938.939.238.739.039.238.938.839.2

38.939.039.239.439.239.539.339.039.439.2

39.138.938.938.838.939.239.539.239.239.338.9

38.739.139.839.639.539.639.338.738.938.838.7

38.838.538.538.838.539.239.539.239.639.339.0

38.939.539.138.938.839.339.139.039.138.939.2

38.938.939.039.339.139.138.939.139.239.4

31284013.3.38.638.938.839.139.038.938.838.938.838.9

39.239.038.939.438.939.039.038.939.139.1

38.938.739.338.939.039.438.839.139.239.6

38.838.939.139.439.039.439.339.339.238.639.3

32187310.3.38.438.638.938.938.838.738.738.838.638.938.7

38.738.938.938.738.839.739.338.938.738.8

39.738.938.839.238.938.939.339.038.939.139.1

39.539.039.139.039.039.039.039.039.139.039.1

39.039.039.039.439.039.039.439.439.238.939.1

38.539.639.739.439.339.039.239.239.639.539.5

39.139.039.439.039.139.239.138.939.039.1

38.838.538.838.838.939.239.439.639.438.9

39.239.439.939.339.539.140.039.739.539.339.4

34393530.6.38.538.738.638.738.638.638.938.738.838.839.1

39.839.239.140.339.139.138.938.939.238.938.8

3469409.4.38.539.338.938.938.338.939.239.039.339.0

39.639.438.839.139.339.139.239.139.139.139.0

38.939.039.738.839.039.038.939.338.838.9

39.139.239.539.639.339.139.239.038.939.038.9

36199723.6.38.438.938.838.838.739.338.839.038.939.039.2

38.839.238.538.739.139.239.139.339.139.439.2

39.339.639.839.339.639.139.339.339.439.139.3

39.539.539.138.538.639.339.639.239.039.2

39.639.339.339.539.139.439.338.639.339.1

370102223.7.38.938.839.038.938.739.039.139.139.038.8

372102831.5.39.239.139.039.038.838.938.939.038.839.0

37310315.8.39.238.838.639.039.039.039.139.039.239.138.9

37610382.7.38.939.038.638.738.738.839.338.838.939.139.2

38.739.038.839.439.740.039.539.439.239.339.2

39.838.838.739.338.939.139.639.139.139.238.9

38.638.438.739.238.839.139.339.639.539.4

38.938.739.139.139.139.039.239.039.339.339.5

38710683.8.38.939.038.938.638.939.039.038.939.339.2

388107222.6.38.638.838.738.638.638.538.538.538.639.1

39.039.639.739.439.238.839.339.139.439.1

39210819.4.39.338.939.1

394109718.4.38.839.138.939.338.839.139.138.838.939.0

39.139.039.039.239.239.339.640.139.639.3

40.239.739.339.939.038.738.638.938.638.7

400110815.4.38.938.738.638.838.838.838.938.738.738.839.0

38.739.139.740.039.739.739.239.239.238.938.9

38.839.939.739.739.439.139.039.138.939.439.0

39.239.239.439.339.138.639.138.838.838.9

38.839.139.138.939.339.139.039.139.239.4

411114413.3.39.338.938.839.038.939.038.838.838.838.938.8

38.940.639.338.838.838.939.239.039.339.3

39.239.239.438.939.539.539.139.238.939.339.2

420120625.7.39.039.239.339.138.938.939.139.039.239.2

38.939.039.038.739.439.438.938.939.038.7

39.339.039.039.439.839.739.240.139.239.4

425122530.5.38.938.738.939.138.638.838.839.139.239.2

42612305.4.38.838.738.839.139.038.939.139.339.339.3

39.839.239.239.138.938.938.939.938.738.7

38.838.938.639.139.438.838.938.638.638.738.5

431124029.4.38.738.938.938.738.738.938.839.039.139.0

432124717.5.38.738.739.038.739.038.939.038.939.039.039.0

39.139.039.139.139.539.639.339.238.939.439.6

39.238.939.339.639.239.239.038.739.039.139.0

39.439.639.239.639.139.039.439.239.539.339.1

38.838.939.539.039.139.039.038.939.039.739.4

44512865.8.39.138.938.939.038.938.939.039.239.039.339.1

39.439.238.539.038.938.739.238.838.639.1

455133125.7.39.038.538.638.939.238.939.339.138.838.938.7

38.738.839.839.339.739.439.139.239.639.339.4

461136613.7.39.038.638.739.039.139.039.139.338.739.3

39.038.938.938.839.039.239.639.739.839.539.7

463137212.6.38.839.139.038.739.239.239.339.039.239.339.0

46413763.7.38.938.838.838.638.938.838.838.838.738.8

39.240.039.739.139.438.839.139.339.038.939.0

38.839.339.038.739.138.839.639.239.039.1

472140621.3.39.238.638.838.838.839.138.639.038.639.139.0

39.539.139.539.939.539.339.038.938.938.738.6

38.938.839.439.540.239.339.039.138.439.038.7

39.539.739.539.039.138.939.039.038.838.6

39.038.939.339.439.639.539.339.339.239.2

39.039.039.739.639.338.939.039.238.839.239.0

39.039.739.739.539.438.638.838.838.738.838.7

39.038.938.939.839.539.239.339.739.439.339.2

38.538.838.838.938.938.939.039.739.239.2

39.240.639.238.538.739.339.139.138.938.939.2

38.939.239.039.439.238.939.139.239.139.339.0

39.139.539.639.539.139.039.038.939.039.1

49614688.5.39.038.839.139.039.039.138.939.138.839.239.3

38.838.638.939.539.439.439.239.239.739.439.4

38.939.539.539.139.139.039.139.439.039.0

500147420.6.38.938.838.938.638.938.639.039.139.139.3

38.938.939.039.539.239.539.339.639.339.4

50414848.4.39.239.039.338.739.039.139.339.238.839.038.9

508149727.4.38.638.539.038.838.938.838.938.538.938.838.9

38.738.839.739.539.239.239.139.139.239.239.1

38.839.539.139.238.9

01234567891055

> 39,72715131573449281

> 39,6366231710668125102

> 39,53914181113148151116132

> 39,45911201611199171922158

> 39,36109181991721142741191

0+11+22+33+44+55+66+77+88+99+10

> 39,7068841421

> 39,6

> 39,5

> 39,4

> 39,3

Tabelle Fieber

Tag derAnzahl der

MessungKühe

post partummit Fieber5183224211286710214081

1. Tag18

2. Tag32

3. Tag24

4. Tag21

5. Tag12

6. Tag8

7. Tag6

8. Tag7

9. Tag10

10. Tag2

Tabelle Fieber

Tag post partum

° C

Tabelle3

4920.4.39.839.640.0540.0539.939.4539.1539.4539.4539.239.35

4712716.6.4039.0539.640.239.9539.439.5539.339.239.138.8

2907901.8.39.838.6538.9538.8538.5539.239.1539.338.9539.239.25

34593728.3.39.839.1539.140.2539.0539.0538.938.939.238.8538.8

380104925.6.39.838.7538.739.338.8539.0539.639.139.0539.238.9

2514.3.39.139.7539.8539.3539.7539.6539.3539.439.1538.8539

51026.6.39.140.0540.2540.239.6539.6539.2539.4539.0538.939.05

4612516.4.39.639.7538.9539.139.139.2539.1539.1539.239.139.35

6416917.6.38.839.939.13939.4539.438.939.2539.539.8539.35

9424728.5.39.14039.438.9539.4539.239.2538.9539.0538.839

10627410.6.3939.8539.4539.1538.953939.0538.838.8538.7539

11929519.5.39.339.8538.8539.539.138.7538.839.2539.239.1538.85

12330823.4.39.14040.9539.339.8539.6539.839.43939.1539.2

18044214.6.40.1540.2539.639.0539.0539.139.0539.639.6539.6

20954022.6.39.839.9539.539.0539.0539.239.0539.0539.239.45

22257715.4.39.8539.93938.238.5538.3538.438.6538.3538.7

25266519.6.39.339.839.639.6539.8539.4539.3539.339.4539.439.6

35396815.3.40.0540.6539.4539.2539.539.1539.239.139.239.4

39911059.3.40.239.739.2539.8538.9538.738.638.938.638.65

402112321.7.38.839.939.6539.739.3539.053939.138.939.3539

427123320.6.39.7539.1539.1539.0538.8538.938.8539.938.6538.7

468139614.3.39.239.9539.6539.0539.438.839.139.2538.9538.939

493145917.5.39.1540.639.238.538.739.339.139.0538.938.939.15

348413.4.38.738.940.1539.640.339.5539.239.239.2539.238.95

4812818.4.39.4540.539.7539.839.439.439.139.13939.05

22658724.3.39.240.539.839.239.239.9539.939.339.0539.05

7418022.5.39.5540.4539.8539.2539.239.539.139.1538.9539.05

81614.4.39.739.439.7540.1539.439.253939.3539.0539.1539.05

10526814.4.39.140.4541.1540.539.1538.938.638.6538.738.7

1644101.6.38.939.5539.839.139.0539.0539.4539.639.2539.2539.25

1102818.4.39.739.2540.139.9538.7539.3539.33938.838.938.55

13733621.3.39.23940.239.339.439.0539.0538.738.7538.938.9

15237510.6.39.638.540.1538.838.8539.139.4539.639.639.5539.65

2045232.6.39.4539.839.1538.739.338.838.6538.938.939

20552531.7.39.740.4539.539.739.139.33939.239.0539.15

24765131.3.39.439.9540.1539.139.339.238.839.3539.0538.65

25969110.4.38.739.54039.339.3539.0539.3539.2538.9539.338.8

27474818.4.39.139.640.540.238.73938.939.0539.138.8539.2

28678028.5.39.239.6539.7539.438.8539.339.139.3393939.1

417119711.3.38.940.5539.338.7538.838.8539.23939.339.25

3008113.5.38.739.139.839.639.539.5539.338.6538.8538.838.7

33591513.3.39.139.639.7539.839.2539.3539.339.339.5539.239.4

34193010.6.39.239.439.8539.2539.4539.054039.6539.4539.339.35

453132713.4.38.839.454040.339.7539.138.9539.2538.738.8538.75

458135631.3.38.738.7539.839.2539.739.439.0539.239.5539.339.35

36299823.3.39.240.239.8539.05393938.9539.138.838.7

366101021.7.39.2539.639.7539.2539.639.0539.339.2539.3539.139.25

18445428.3.38.5539.239.839.3539.0538.739.0538.6539.2539.2

2566857.6.39.539.639.9539.139.138.839.139.439.9539.2

41912037.6.3939.239.6540.0539.7539.3539.0539.139.153939.05

474140821.7.39.539.0539.539.8539.4539.33938.8538.8538.738.6

21354920.5.38.638.8539.239.8539.9539.2539.2539.1539.339.439.55

276412.7.38.738.7539.4539.8540.240.139.6539.4539.3539.539.3

48714495.4.38.8539.3540.3540.139.239.639.1539.0538.7538.7

401112228.4.38.739.139.654039.6539.6539.239.239.1538.938.85

49114581.4.3938.938.939.839.4539.239.2539.739.439.339.15

7117625.5.38.838.953939.439.839.339.3538.9538.938.738.9

701755.4.3939.053939.5540.0539.839.939.839.639.2539.5

15639010.4.39.238.939.0540.340.339.5539.2539.439.139

2777571.8.38.938.6539.139.539.8539.55393939.0538.9538.7

32388024.4.39.239.6538.939.0540.140.339.639.138.9539.139

404113028.7.39.4539.139.640.440.639.6539.639.539.339.45

478141712.7.38.938.7539.439.4540.1539.253939.0538.438.9538.7

1734326.6.39.238.838.638.9539.440.4538.9538.7539.238.9539.05

31585025.7.39.538.9539.0539.439.639.839.7539.8539.4539.7539.55

18144622.4.39.3538.738.7538.939.3539.8539.4539.0539.3539.3539.15

35598115.3.39.2539.239.4539.1539.93939.44040.2539.8

379104823.6.38.738.9538.839.439.74039.539.439.1539.2539.2

422121625.5.39.2538.953939.3539.7539.739.240.0539.1539.35

513151024.7.3939.339.639.6539.4540.2540.339.739.639.2540.85

2406314.5.39.338.8538.8538.939.2539.5539.8539.2539.539.439.1

48914524.6.39.438.9539.1539.2539.239.3539.7539.839.739.2539.55

511150915.4.39.0539.0538.838.8539.1539.4539.440.2540.6540.0539.15

2245792.4.39.0539.139.0539.5539.439.3540.0539.6539.4539.2

396109918.7.39.138.9538.9539.239.1539.339.640.0539.639.3

449131319.6.39.138.7538.7539.6539.3539.439.639.439.9539.839.05

462137022.5.3938.938.8538.83939.239.639.6539.839.539.65

184310.3.39.0538.738.738.7538.6538.738.8538.840.238.6

18345327.7.39.0539.139.339.1539.2539.339.238.9539.439.7539.3

23460815.7.38.939.2539.739.438.8539.5539.4539.439.639.9539.6

2546742.7.39.138.9538.438.753938.8539.2539.1539.8538.9

MW

Min

Max

Stabw.

38,5

39

39,5

12345678910

Tag

post partum

°C

MBD002497E1.xls

Diagramm1

39.10.3900441340.390044134

39.10.48402045640.4840204564

39.20.40714405750.4071440575

39.10.37866128680.3786612868

39.10.34170100750.3417010075

39.10.30228791590.3022879159

39.10.29386195440.2938619544

39.10.31901197680.3190119768

39.10.31245312060.3124531206

39.10.28392511140.2839251114

Tag post partum

°C

gesund gesamt

Tag derTageszeitMWsMinMaxMWsMinMax

Messungin °Cin °Cin °Cin °Cin °Cin °Cin °Cin °C

Tag partusmorgens39.20.313809162538.739.739.0434782609

abends39.02392638040.308487820338.4400.313033578738.440

1. Tagmorgens39.00871212120.423680964238.140.4

post partumabends39.09545454550.500321362338.140.839.05208333330.465177749238.140.8

2. Tagmorgens39.07537878790.495109014138.241039.04347826090.3130335787

post partumabends39.22357414450.572038808238.441.439.14933586340.53949925338.241.4139.05208333330.4651777492

3. Tagmorgens39.09885496180.444591406938.340.7239.14933586340.539499253

post partumabends39.2087786260.505258968438.341.639.15381679390.478610094138.341.6339.15381679390.4786100941

4. Tagmorgens39.03854961830.42018354343840.9439.14110898660.4518717073

post partumabends39.24406130270.45986325323841.539.14110898660.45187170733841.5539.10536398470.4065797154

5. Tagmorgens39.02605363980.400109769838.341.3639.11264367820.3612107804

post partumabends39.18467432950.39816259438.140.639.10536398470.406579715438.141.3739.10095785440.3542706846

6. Tagmorgens39.03448275860.347682742138.440.3839.10057581570.3663484765

post partumabends39.19080459770.35818952353840.639.11264367820.36121078043840.6939.07567049810.3671778958

7. Tagmorgens39.02337164750.317849946238.2401039.0628352490.3287824448

post partumabends39.17854406130.372000034938.440.939.10095785440.354270684638.240.9

8. Tagmorgens39.05632183910.363857902138.240.7

post partumabends39.1450.364143359338.44139.10057581570.366348476538.24139.0998063926

9. Tagmorgens39.02720306510.369702886138.241.20.0383060732

post partumabends39.1241379310.358833210938.140.439.07567049810.367177895838.141.239.0434782609

10. Tagmorgens39.00536398470.333815301438.44139.1538167939

post partumabends39.12030651340.313922917338.440.739.0628352490.328782444838.441

moab

039.20.313809162538.739.739.02392638040.308487820338.4400.176

139.00871212120.423680964238.140.439.09545454550.500321362338.140.80.0867424242

239.07537878790.495109014138.24139.22357414450.572038808238.441.40.1481953566

339.09885496180.444591406938.340.739.2087786260.505258968438.341.60.1099236641

439.03854961830.42018354343840.939.24406130270.45986325323841.50.2055116844

539.02605363980.400109769838.341.339.18467432950.39816259438.140.60.1586206897

639.03448275860.347682742138.440.339.19080459770.35818952353840.60.1563218391

739.02337164750.317849946238.24039.17854406130.372000034938.440.90.1551724138

839.05632183910.363857902138.240.739.1450.364143359338.4410.0886781609

939.02720306510.369702886138.241.239.1241379310.358833210938.140.40.0969348659

1039.00536398470.333815301438.44139.12030651340.313922917338.440.70.1149425287

MW0.1360948752

s0.0389716544

0.0867424242

0.2055116844

gesund gesamt

00

00

00

00

00

00

00

00

00

00

00

morgens

abends

Tag post partum

°C

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

0

Tabelle2

00.31303357870.3130335787

00.46517774920.4651777492

00.5394992530.539499253

00.47861009410.4786100941

00.45187170730.4518717073

00.40657971540.4065797154

00.36121078040.3612107804

00.35427068460.3542706846

00.36634847650.3663484765

00.36717789580.3671778958

00.32878244480.3287824448

Tag post partum

°C

0

0

0

0

0

0

0

0

0

0

0

Tabelle3

Diagnostik

Temperatur- Metritis puerperalis

grenze in °C Sensitivität Spezifität

> 39,3 0,9 0,3

> 39,4 0,8 0,4

> 39,5 0,8 0,5

> 39,6 0,7 0,6

> 39,7 0,6 0,7

Sensitivität und Spezifität unterschiedlicher Temperaturgrenzwerte zur Detektion einer Metritis puerperalis (n = 74)

Diagnostik

Schulungspotential in Abhängigkeit zur betrieblichen Situation

VorführenderPräsentationsnotizenFAMACHA SCORE

Transrektale Palpation- Größe: in Abhängigkeit zum Zeitpunkt post partum

- körperlich anstrengend- Tonisierung- Zervixdurchmesser- Sonstige Befunde, um das

Krankheitsbild richtig einzuschätzen

Diagnostik

Vaginale Untersuchung- Hygiene (Kuh und Gerät)- Schmerz bzw. Stress (Pilz et al., 2014)

- sinnvoll zur Erfassung des gesamten Krankheitsbildes (z. B. Geburtsverletzungen), Möglichkeit des Zeigens

- Cave: Bei geschlossener Zervix kann eine ungestörte Uterusinvolution vorgetäuscht werden

Diagnostik

Diagnostik

VorführenderPräsentationsnotizenBis zu 20 % Verlust – Meeressäuger bis zu 40 %

Diagnostik - Ultraschall

Referenzbereiche für den ultrasonographisch gemessenen Durchmesservon Zervix und Uterus für Fleckviehkühen mit einem physiologischenPuerperium am 42. Tag p. p. in cm (n = 102) (aus Hofer, 2019)

Physiologisches

Puerperium

Zervix 2,3 - 3,0

Corpus 2,0 – 2,7

Rechtes Horn 1,8 – 2,2

Linkes Horn 1,7 – 2,2

VorführenderPräsentationsnotizenBis zu 20 % Verlust – Meeressäuger bis zu 40 %

Methoden im Vergleich

- Wichtig für die individuelle Behandlung ist eine umfassende Diagnostik (auch Prävention)

Betrieb 1: Metritiden mit GeburtsverletzungenBetrieb 2: Metritiden, antepartal NEFA hoch

Diagnostik

VorführenderPräsentationsnotizenBis zu 20 % Verlust – Meeressäuger bis zu 40 %

- Uterustupferprobenentnahme- Annahme: Der gesunde Uterus ist steril.

Es gibt „maligne Keime“.

Diagnostik

Pathogene Fakultativ Pathogene Opportunisten

Trueperella pyogenes Bacillus licheniformis Clostridium perfringens

Prevotella melaninogenica Enterococcus faecalis Klebsiella pneumonia

Escherichia coli Mannheimia haemolytica Micrococcus spp.

Fusobacterium necrophorum Pasteurella multocida Providencia stuartii

Proteus spp. Peptostreptococcus species

Koagulase negative Streptokokken

Staphylococcus aureus α-hämolysierende Streptokokken

Nicht hämolysierende Streptokokken

Streptococcus acidominimusAspergillus spp.

Williams et al. 2007Klares Weltbild: Freund, Feind

Diagnostik

Diagnostik

E. coli Wegbereiter für T. pyogenes

T. pyogenes

Fusobacterium necrophorumLeukotoxin

Prevotella melaninogenicusphagozytoseunterdrückendes Toxin

Koagulase negative Staphylokokken

α-hämolysierende Streptokokken

Bestimmte Keimgruppen stellen eine Schutz- bzw. Induktionsfunktion für die Ausbildung einer Uterusinfektion dar.

VorführenderPräsentationsnotizen

Diagnostik

VorführenderPräsentationsnotizen12 Kühe, 2019: ein Milliarde Rinder auf der Welt, Probe Tag 0 (20 Minuten) und Tag 2

- Eine gewisse mikrobiologische Besiedlung scheint normal zu sein „residentes uterines Mikrobiom“ (auch bei Färsen und trächtigen Kühen)

- Individuell und wird früh im Leben erworben („durch die vaginale Geburt“)

- Auch bei ungestörten Trächtigkeiten wurden Bakterien gefunden, die als pathogen gelten:- Trueperella spp.- Acinetobacter spp.- Fusobacteria spp.

Diagnostik

VorführenderPräsentationsnotizen16 S rRNA sequenzing, 10 Färsen im Östrus – 5 trächtige Kühe

- Die Nachweis von Mikroorganismen hängt von der Methode ab.

- Giudice (2016): weniger als 1% wachsen unter herkömmlichen Kultivierungsbedingungen

- Schwierigkeiten des Vergleiches von Ergebnissen bei Anwendung unterschiedlicher Techniken

- Wer nur Bakterien sucht, wird nur Bakterien finden.

Diagnostik

In conclusion, BoHV-4 infection is associated with reduced chances for insemination and pregnancy by 200 dpp and showed a trend to be associated with increased risk for clinical endometritis. Furthermore, BoHV-4 and Trueperella pyogenes infections are strongly related.

- Ausscheidung mit dem Nasensekret, zellassoziierte Virämie

- Tropismus zu Gefäßendothelzellen, Mammagewebe, Endometrium, Fetus

- Nachweis im Zusammenhang mit: Metritis, Vulvovaginitis, Endometritis, Aborten und häufiger im Uterus bei umrindernden Tieren

- Zur Krankheitsauslösung Kooperation mit Bakterien notwendig

Diagnostik

- 111 Kühe, vaginale Proben -7., 0, 3., 7. Tag

- später Metritis: Proteobacteria (-7., 0.), Fusobacteria (3., 7.)

- später Endometritis: Bacteroidetes (7.)

Diagnostik

VorführenderPräsentationsnotizenNext generation sequenzing 16 S r RNA and quantitative PCR

Phylum Stamm- Klasse – Ordnung - Familie

- 112 Kühe, wiederholt post partum aus Uterus- Technik, die auf aerober Kultur basiert: 202 verschiedene Spezies

- S. uberis an Tag 3 erhöht das Risiko einer späteren T. pyogenes-Infektionan Tag 9

- S. uberis ist nicht gleich S. uberis- - Unterschiede zwischen Kühen mit unterschiedlichen Ausflußqualitäten

Diagnostik

VorführenderPräsentationsnotizenFourier-Transform-Infarotspektrometrie, Kultiviert Mikroorganismen vergleicht deren Spektren mit Datenbanken – Genus manchmal Speziesdiagnostik

- Nur ein Bruchteil wird mit den Methoden in der „normalen“ Diagnostik erfasst

- sehr dynamisch

- Keimkonstellationen und –populationen

- Statistik: Zuordnung zu „gefährlicher“, „harmloser“, „nützlicher“ Keim

Diagnostik

- Antibiotika

- Hormone

- Schmerzmittel

- Infusionen

- Begleitmaßnahmen: - Aufstallung, Fütterung, Tränke, usw.

Therapie

Selbstheilungsrate bis zu 55 %

- Antibiotika: Reduktion, rechtliche Vorgaben,Es fehlen gute Vergleichsstudien zwischen AB und Alternativen (Haimerl et al., 2017)Kein vollständiger Verzicht auf AB möglich (Pohl et al., 2016)

- Hormone: siehe nächster Vortrag

- Schmerzmittel

- Begleitmaßnahmen: - Aufstallung, Fütterung, Tränke, usw.

Therapie

Was sagen andere?

Antibiotika

Therapie

- Schmerzhafte Erkrankung

Therapie

- Definition: > 39,5 C, geruchlich-abweichender, wässrig-rötlicher Ausfluß, erste zehn Tage post partum

- Sechs Betriebe in Nordostdeutschland (732 – 2244 Milchkühe)

- Randomisierte Gruppenzuteilung:Gruppe 1: Ketoprofen (3 mg/kg KM)Gruppe 2: Ceftiofur (1 mg /kg KM)beide Gruppen wurden über drei Tage behandelt

Therapie

- Randomisierte Gruppenzuteilung:Gruppe 1: Ketoprofen (3 mg/kg KM), 300 Kühe -35Gruppe 2: Ceftiofur (1 mg /kg KM), 310 Kühe -17

- > 39,5 Grad C an Tag 4:

- weitere Behandlung antibiotisch: G1 3 Tage, G2 2 Tage

- Weiteres Fieber: individuelle Behandlung

Therapie

- Randomisierte Gruppenzuteilung:Gruppe 1: Ketoprofen (3 mg/kg KM)Gruppe 2: Ceftiofur (1 mg /kg KM)

Ergebnisse:

Bei 61% der Kühe aus Gruppe 1 musste eine antibiotische Behandlungsverlängerung durchgeführt werden (Gruppe 2: 31 %)

- Gruppe 1: signifikante Einsparung von Antibiotika

- Prävention

- Immunmodulation (Impfung gegen „Metritis“)

- Kombinationsbehandlungen

Wie geht es weiter?

- Kombination von Methoden - Praxisrelevanz

- Automatische Methoden: Vorauswahl gut

- Herausforderung an die frühe Diagnostik

- Therapie: Standards mit individueller Komponente (Kuh und Betrieb)

Zusammenfassung

Update zur Diagnose und Therapie von Uterusinvolutionsstörungen

Axel Wehrend

Klinikum Veterinärmedizin - Klinik für Geburtshilfe, Gynäkologie und Andrologie der Groß- und Kleintiere mit Tierärztlicher Ambulanz der JLU

Gießen

KlinikumVeterinärmedizin

Foliennummer 1Foliennummer 2Foliennummer 3Foliennummer 4Foliennummer 5Foliennummer 6Foliennummer 7Foliennummer 8Foliennummer 9Foliennummer 10Foliennummer 11Foliennummer 12Foliennummer 13Foliennummer 14Foliennummer 15Foliennummer 16Foliennummer 17Foliennummer 18Foliennummer 19Foliennummer 20Foliennummer 21Foliennummer 22Foliennummer 23Foliennummer 24Foliennummer 25Foliennummer 26Foliennummer 27Foliennummer 28Foliennummer 29Foliennummer 30Foliennummer 31Foliennummer 32Foliennummer 33Foliennummer 34Foliennummer 35Foliennummer 36Foliennummer 37Foliennummer 38Foliennummer 39Foliennummer 40Foliennummer 41Foliennummer 42Foliennummer 43Foliennummer 44Foliennummer 45